ACE inhibitory peptide KYIPIQ derived from yak milk casein induces nitric oxide production in HUVECs and diffuses via a transcellular mechanism in Caco-2 monolayers

Potential Precursor of Angiotensin-I Converting Enzyme (ACE) Inhibitory Activity and Structural Properties of Peptide from Peptic Hydrolysate of Cutlassfish Muscle

(2020) Hyun-Soo Kim et al.   Journal of Aquatic Food Product Technology

Low-molecular weight peptides isolated from seahorse (Hippocampus abdominalis) improve vasodilation via inhibition of angiotensin-converting enzyme in vivo and in vitro

(2020) Jun-Geon Je et al.   PROCESS BIOCHEMISTRY

Rice bran-derived tripeptide exhibits vasorelaxant and anti-hypertensive effects dependent on the endothelial NO system

(2019) naohisa shobako et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Eight antihypertensive peptides from the protein hydrolysate of Antarctic krill (Euphausia superba): Isolation, identification, and activity evaluation on human umbilical vein endothelial cells (HUVECs)

(2019) Yu-Qin Zhao et al.   FOOD RESEARCH INTERNATIONAL

Yak milk casein as potential precursor of angiotensin I-converting enzyme inhibitory peptides based on in silico proteolysis

(2018) Kai Lin et al.   FOOD CHEMISTRY

The antioxidant activity and transcellular pathway of Asp-Leu-Glu-Glu in a Caco-2 cell monolayer

(2018) Lujuan Xing et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY

Quantitative Structure–Activity Relationship Modeling Coupled with Molecular Docking Analysis in Screening of Angiotensin I-Converting Enzyme Inhibitory Peptides from Qula Casein Hydrolysates Obtained by Two-Enzyme Combination Hydrolysis

(2018) Kai Lin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Conformational stabilization of a β-hairpin through a triazole–tryptophan interaction

(2018) Donatella Diana et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Vasodilator and hypotensive effects of the spider peptide Lycosin-I in vitro and in vivo

(2018) Binbin Ma et al.   PEPTIDES

Whey protein hydrolysate induced modulation of endothelial cell gene expression

(2018) Martina B. O'Keeffe et al.   Journal of Functional Foods

Angiotensin-converting enzyme inhibitory peptides from goats' milk released by in vitro gastro-intestinal digestion

(2017) Davide Tagliazucchi et al.   INTERNATIONAL DAIRY JOURNAL

Transepithelial Transport of YWDHNNPQIR and Its Metabolic Fate with Cytoprotection against Oxidative Stress in Human Intestinal Caco-2 Cells

(2017) Feiran Xu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Transepithelial transport of milk-derived angiotensin I-converting enzyme inhibitory peptide with the RLSFNP sequence

(2017) Yuxing Guo et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Effect of angiotensin I-converting enzyme (ACE) inhibition and nitric oxide (NO) production of 6,6′-bieckol, a marine algal polyphenol and its anti-hypertensive effect in spontaneously hypertensive rats

(2017) Seok-Chun Ko et al.   PROCESS BIOCHEMISTRY

Purification and molecular docking study of angiotensin I-converting enzyme (ACE) inhibitory peptides from hydrolysates of marine sponge Stylotella aurantium

(2017) Seok-Chun Ko et al.   PROCESS BIOCHEMISTRY

Revisiting the mechanisms of ACE inhibitory peptides from food proteins

(2017) Jianping Wu et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Transport of angiotensin converting enzyme and renin dual inhibitory peptides LY, RALP and TF across Caco-2 cell monolayers

(2017) Yi-Jie Yang et al.   Journal of Functional Foods

Transport of soybean protein-derived antihypertensive peptide LSW across Caco-2 monolayers

(2017) Qinlu Lin et al.   Journal of Functional Foods

Novel angiotensin I-converting enzyme inhibitory peptides from protease hydrolysates of Qula casein: Quantitative structure-activity relationship modeling and molecular docking study

(2017) Kai Lin et al.   Journal of Functional Foods

ACE- inhibitory and radical scavenging activities of bioactive peptides obtained from camel milk casein hydrolysis with proteinase K

(2016) Mahmood Rahimi et al.   Dairy Science & Technology

Transepithelial transport of milk derived bioactive peptide VLPVPQK

(2016) Rishika Vij et al.   FOOD CHEMISTRY

Angiotensin I–converting enzyme–inhibitory peptides from bovine collagen: insights into inhibitory mechanism and transepithelial transport

(2016) Yu Fu et al.   FOOD RESEARCH INTERNATIONAL

Vasorelaxant effects of camel and bovine casein tryptic hydrolysates in rat thoracic aorta and their antihypertensive effect in awake spontaneously hypertensive rats

(2016) Hassan Kanso et al.   INTERNATIONAL DAIRY JOURNAL

Generation of Bioactive Hydrolysates and Peptides from Bovine Hemoglobin withIn VitroRenin, Angiotensin-I-Converting Enzyme and Dipeptidyl Peptidase-IV Inhibitory Activities

(2016) Tomas Lafarga et al.   JOURNAL OF FOOD BIOCHEMISTRY

Transport of Antihypertensive Peptide RVPSL, Ovotransferrin 328–332, in Human Intestinal Caco-2 Cell Monolayers

(2015) Long Ding et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

An antihypertensive lactoferrin hydrolysate inhibits angiotensin I-converting enzyme, modifies expression of hypertension-related genes and enhances nitric oxide production in cultured human endothelial cells

(2015) Aurora García-Tejedor et al.   Journal of Functional Foods

Angiotensin I-converting enzyme (ACE) inhibition and nitric oxide (NO)-mediated antihypertensive effect of octaphlorethol A isolated from Ishige sinicola: In vitro molecular mechanism and in vivo SHR model

(2015) Seok-Chun Ko et al.   Journal of Functional Foods

Are intact peptides absorbed from the healthy gut in the adult human?

(2015) Warren M. Miner-Williams et al.   NUTRITION RESEARCH REVIEWS

Transport of Egg White ACE-Inhibitory Peptide, Gln-Ile-Gly-Leu-Phe, in Human Intestinal Caco-2 Cell Monolayers with Cytoprotective Effect

(2014) Long Ding et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Mechanisms of food protein-derived antihypertensive peptides other than ACE inhibition

(2014) Chibuike C. Udenigwe et al.   Journal of Functional Foods

In vitro transport and satiety of a beta-lactoglobulin dipeptide and beta-casomorphin-7 and its metabolites

(2014) Simone Osborne et al.   Food & Function

Systemic and renal oxidative stress in the pathogenesis of hypertension: modulation of long-term control of arterial blood pressure by resveratrol

(2014) Shereen M. Hamza et al.   Frontiers in Physiology

Bioavailability of antihypertensive lactoferricin B-derived peptides: Transepithelial transport and resistance to intestinal and plasma peptidases

(2013) Ricardo Fernández-Musoles et al.   INTERNATIONAL DAIRY JOURNAL

Effect of pH on heat stability of yak milk protein

(2013) Qiming Li et al.   INTERNATIONAL DAIRY JOURNAL

Transport of IRW, an Ovotransferrin-Derived Antihypertensive Peptide, in Human Intestinal Epithelial Caco-2 Cells

(2013) Satyanarayana Bejjani et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Purification and identification of novel angiotensin-I converting enzyme (ACE) inhibitory peptides from cultured marine microalgae (Nannochloropsis oculata) protein hydrolysate

(2013) Kalpa Wishvajith Samarakoon et al.   JOURNAL OF APPLIED PHYCOLOGY

The Kallikrein-Kinin system

(2012) P. Hillmeister et al.   Acta Physiologica

Models to Predict Intestinal Absorption of Therapeutic Peptides and Proteins

(2012) Filipa Antunes et al.   CURRENT DRUG METABOLISM

Nitric oxide-mediated vasorelaxation effects of anti-angiotensin I-converting enzyme (ACE) peptide from Styela clava flesh tissue and its anti-hypertensive effect in spontaneously hypertensive rats

(2012) Seok-Chun Ko et al.   FOOD CHEMISTRY

Gomisin J from Schisandra chinensis induces vascular relaxation via activation of endothelial nitric oxide synthase

(2012) Ji Young Park et al.   VASCULAR PHARMACOLOGY

Long-term intake of a milk casein hydrolysate attenuates the development of hypertension and involves cardiovascular benefits

(2011) David Sánchez et al.   PHARMACOLOGICAL RESEARCH

Casein-derived bioactive peptides: Biological effects, industrial uses, safety aspects and regulatory status

(2009) Martha Phelan et al.   INTERNATIONAL DAIRY JOURNAL

Modulation of endothelial nitric oxide by plant-derived products

(2009) Christoph A. Schmitt et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Transepithelial transport across Caco-2 cell monolayers of antihypertensive egg-derived peptides. PepT1-mediated flux of Tyr-Pro-Ile

(2008) Marta Miguel et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Bioavailability of the antihypertensive peptide LHLPLP: Transepithelial flux of HLPLP

(2007) Ana Quirós et al.   INTERNATIONAL DAIRY JOURNAL