Systemic and renal oxidative stress in the pathogenesis of hypertension: modulation of long-term control of arterial blood pressure by resveratrol

Sirtuins as Novel Targets for Alzheimer's Disease and Other Neurodegenerative Disorders: Experimental and Genetic Evidence

(2017) Diego Albani et al.   JOURNAL OF ALZHEIMERS DISEASE

The journey of resveratrol from yeast to human

(2016) Silvie Timmers et al.   Aging-US

Resveratrol prevents AngII-induced hypertension via AMPK activation and RhoA/ROCK suppression in mice

(2014) Xia Cao et al.   HYPERTENSION RESEARCH

Antihypertensive effects of the flavonoid quercetin

(2014) Francisco Perez-Vizcaino et al.   Pharmacological Reports

Resveratrol Levels and All-Cause Mortality in Older Community-Dwelling Adults

(2014) Richard D. Semba et al.   JAMA Internal Medicine

Resveratrol: Therapeutic Potential for Improving Cardiometabolic Health

(2013) R. M. Pollack et al.   AMERICAN JOURNAL OF HYPERTENSION

Resveratrol and grape juice differentially ameliorate cardiovascular autonomic modulation in L-NAME-treated rats

(2013) Denise Ruttke Dillenburg et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Resveratrol prevents hypertension and cardiac hypertrophy in hypertensive rats and mice

(2013) Vernon W. Dolinsky et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Role of CNS in Salt-sensitive Hypertension

(2013) Megumi Fujita et al.   CURRENT HYPERTENSION REPORTS

Anti-Inflammatory and Antioxidant Effects of Resveratrol in Healthy Smokers A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Trial

(2013) S. Bo et al.   CURRENT MEDICINAL CHEMISTRY

Calorie restriction and sirtuins revisited

(2013) L. Guarente   GENES & DEVELOPMENT

Renal Dopamine Receptors, Oxidative Stress, and Hypertension

(2013) Santiago Cuevas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Renal Protective Effects of Resveratrol

(2013) Munehiro Kitada et al.   Oxidative Medicine and Cellular Longevity

Therapeutic Roles of Heme Oxygenase-1 in Metabolic Diseases: Curcumin and Resveratrol Analogues as Possible Inducers of Heme Oxygenase-1

(2013) Yong Son et al.   Oxidative Medicine and Cellular Longevity

One-year supplementation with a grape extract containing resveratrol modulates inflammatory-related microRNAs and cytokines expression in peripheral blood mononuclear cells of type 2 diabetes and hypertensive patients with coronary artery disease

(2013) João Tomé-Carneiro et al.   PHARMACOLOGICAL RESEARCH

Resveratrol as a therapeutic agent for renal fibrosis induced by unilateral ureteral obstruction

(2013) Jin Liang et al.   RENAL FAILURE

The 2011 Canadian Hypertension Education Program Recommendations for the Management of Hypertension: Blood Pressure Measurement, Diagnosis, Assessment of Risk, and Therapy

(2012) Doreen M. Rabi et al.   CANADIAN JOURNAL OF CARDIOLOGY

Molecular Mechanisms of Hypertension—Reactive Oxygen Species and Antioxidants: A Basic Science Update for the Clinician

(2012) Augusto C. Montezano et al.   CANADIAN JOURNAL OF CARDIOLOGY

Biochemistry, Physiology, and Pathophysiology of NADPH Oxidases in the Cardiovascular System

(2012) Bernard Lassègue et al.   CIRCULATION RESEARCH

Sirtuins and renal diseases: relationship with aging and diabetic nephropathy

(2012) Munehiro Kitada et al.   CLINICAL SCIENCE

Renal Denervation in Human Hypertension: Mechanisms, Current Findings, and Future Prospects

(2012) Markus P. Schlaich et al.   CURRENT HYPERTENSION REPORTS

High-Dose Resveratrol Supplementation in Obese Men: An Investigator-Initiated, Randomized, Placebo-Controlled Clinical Trial of Substrate Metabolism, Insulin Sensitivity, and Body Composition

(2012) M. M. Poulsen et al.   DIABETES

Angiotensin-converting enzyme 2 antagonizes angiotensin II-induced pressor response and NADPH oxidase activation in Wistar-Kyoto rats and spontaneously hypertensive rats

(2012) Jennifer Lo et al.   EXPERIMENTAL PHYSIOLOGY

Asymmetric Dimethylarginine and Reactive Oxygen Species

(2012) Christopher S. Wilcox   HYPERTENSION

The Effect of Pressure-Induced Mechanical Stretch on Vascular Wall Differential Gene Expression

(2012) M.A. Anwar et al.   JOURNAL OF VASCULAR RESEARCH

Resveratrol-poor Red Wines Modulate SIRT1 in Human Renal Cells

(2012) Giulia Stiaccini et al.   PLANT FOODS FOR HUMAN NUTRITION

Resveratrol as a calorie restriction mimetic: therapeutic implications

(2012) Jay H. Chung et al.   TRENDS IN CELL BIOLOGY

Resveratrol: French Paradox Revisited

(2012) Betul Catalgol et al.   Frontiers in Pharmacology

From form to function: the role of Nox4 in the cardiovascular system

(2012) Feng Chen et al.   Frontiers in Physiology

The differential effect of resveratrol on the renal artery of normal and diabetic rats

(2012) Ljiljana C Gojković-Bukarica et al.   BMC Pharmacology & Toxicology

ROS-induced ROS release in vascular biology: redox-redox signaling

(2011) Natalya S. Zinkevich et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Chronic estradiol-17β exposure increases superoxide production in the rostral ventrolateral medulla and causes hypertension: reversal by resveratrol

(2011) Madhan Subramanian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Renal oxidative stress, oxygenation, and hypertension

(2011) Fredrik Palm et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Oxidative stress contributes to sex differences in angiotensin II-mediated hypertension in spontaneously hypertensive rats

(2011) Kanchan Bhatia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Chronic exercise modulates RAS components and improves balance between pro- and anti-inflammatory cytokines in the brain of SHR

(2011) Deepmala Agarwal et al.   BASIC RESEARCH IN CARDIOLOGY

Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2–Keap1 signaling

(2011) P. Palsamy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients

(2011) Pál Brasnyó et al.   BRITISH JOURNAL OF NUTRITION

Resveratrol: A multitargeted agent for age-associated chronic diseases

(2011) Kuzhuvelil B. Harikumar et al.   CELL CYCLE

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

(2011) Silvie Timmers et al.   Cell Metabolism

G Protein Coupled Receptor Kinases as Therapeutic Targets in Cardiovascular Disease

(2011) Stephen L. Belmonte et al.   CIRCULATION RESEARCH

Immune-related effects in hypertension and target-organ damage

(2011) Dominik N Muller et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Resveratrol Improves Cardiovascular Function in DOCA-Salt Hypertensive Rats

(2011) Vincent Chan et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

The Role of Nitric Oxide on Endothelial Function

(2011) Dimitris Tousoulis et al.   Current Vascular Pharmacology

Resveratrol prevents endothelial nitric oxide synthase uncoupling and attenuates development of hypertension in spontaneously hypertensive rats

(2011) Siddhartha R. Bhatt et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Angiotensin II and the vascular phenotype in hypertension

(2011) Carmine Savoia et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Increased oxidative stress, the renin–angiotensin system, and sympathetic overactivation induce hypertension in kidney androgen-regulated protein transgenic mice

(2011) María T. Grande et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive oxygen species in cardiovascular disease

(2011) Koichi Sugamura et al.   FREE RADICAL BIOLOGY AND MEDICINE

Vitamins C and E: Beneficial effects from a mechanistic perspective

(2011) Maret G. Traber et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidases and peroxidases in cardiovascular and lung disease: New concepts in reactive oxygen species signaling

(2011) Imad Al Ghouleh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Autonomic-Immune-Vascular Interaction

(2011) Jasenka Zubcevic et al.   HYPERTENSION

Mixed Messages on Blood Pressure Goals

(2011) Aram V. Chobanian   HYPERTENSION

Role of Vascular Extracellular Superoxide Dismutase in Hypertension

(2011) Heinrich E. Lob et al.   HYPERTENSION

Superoxide Modulates Myogenic Contractions of Mouse Afferent Arterioles

(2011) En Yin Lai et al.   HYPERTENSION

Sympathoexcitation by Brain Oxidative Stress Mediates Arterial Pressure Elevation in Salt-Induced Chronic Kidney Disease

(2011) Megumi Fujita et al.   HYPERTENSION

A Resveratrol and Polyphenol Preparation Suppresses Oxidative and Inflammatory Stress Response to a High-Fat, High-Carbohydrate Meal

(2011) Husam Ghanim et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Baroreflex Activation Therapy Lowers Blood Pressure in Patients With Resistant Hypertension

(2011) John D. Bisognano et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Resveratrol improves renal microcirculation, protects the tubular epithelium, and prolongs survival in a mouse model of sepsis-induced acute kidney injury

(2011) Joseph H. Holthoff et al.   KIDNEY INTERNATIONAL

Temporal relation of cardiac hypertrophy, oxidative stress, and fatty acid metabolism in spontaneously hypertensive rat

(2011) Sreeja Purushothaman et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Resveratrol Improves Survival, Hemodynamics and Energetics in a Rat Model of Hypertension Leading to Heart Failure

(2011) Stéphanie Rimbaud et al.   PLoS One

High Salt Intake Delayed Angiotensin II-Induced Hypertension in Mice With a Genetic Variant of NADPH Oxidase

(2010) M. Z. Haque et al.   AMERICAN JOURNAL OF HYPERTENSION

Enhanced myogenic response in the afferent arteriole of spontaneously hypertensive rats

(2010) YiLin Ren et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Dietary salt enhances angiotensin-II-induced superoxide formation in the rostral ventrolateral medulla

(2010) Valdir A. Braga   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Resveratrol, a dietary polyphenolic phytoalexin, is a functional scavenger of peroxynitrite

(2010) Joseph H. Holthoff et al.   BIOCHEMICAL PHARMACOLOGY

Pathogenesis and Clinical Physiology of Hypertension

(2010) Mukesh Singh et al.   CARDIOLOGY CLINICS

Natural Antioxidants and Hypertension: Promise and Challenges

(2010) Tinoy J. Kizhakekuttu et al.   Cardiovascular Therapeutics

Emerging roles of SIRT1 in vascular endothelial homeostasis

(2010) Michael Potente et al.   CELL CYCLE

Therapeutic Targeting of Mitochondrial Superoxide in Hypertension

(2010) Anna E. Dikalova et al.   CIRCULATION RESEARCH

Serum Bilirubin and Genes Controlling Bilirubin Concentrations as Biomarkers for Cardiovascular Disease

(2010) J.-P. Lin et al.   CLINICAL CHEMISTRY

Oxidative Stress and Vascular Function: Implications for Pharmacologic Treatments

(2010) Antje R. Weseler et al.   CURRENT HYPERTENSION REPORTS

The Cardiovascular Nutrapharmacology of Resveratrol: Pharmacokinetics, Molecular Mechanisms and Therapeutic Potential

(2010) Paul A. Kroon et al.   CURRENT MEDICINAL CHEMISTRY

Redox active secondary metabolites

(2010) Claus Jacob et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Dopamine D1 receptor-mediated inhibition of NADPH oxidase activity in human kidney cells occurs via protein kinase A–protein kinase C cross talk

(2010) Peiying Yu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Calorie Restriction Prevents Hypertension and Cardiac Hypertrophy in the Spontaneously Hypertensive Rat

(2010) Vernon W. Dolinsky et al.   HYPERTENSION

Oxidative Stress and Endothelial Dysfunction in Aortas of Aged Spontaneously Hypertensive Rats by NOX1/2 Is Reversed by NADPH Oxidase Inhibition

(2010) Sven Wind et al.   HYPERTENSION

mPGES-1 Protects Against DOCA-Salt Hypertension via Inhibition of Oxidative Stress or Stimulation of NO/cGMP

(2010) Zhanjun Jia et al.   HYPERTENSION

Kidney-Induced Hypertension Depends on Superoxide Signaling in the Rostral Ventrolateral Medulla

(2010) Elizabeth B. Oliveira-Sales et al.   HYPERTENSION

Reactive oxygen species and vascular biology: implications in human hypertension

(2010) Rhian M Touyz et al.   HYPERTENSION RESEARCH

Think locally: evaluation of the microcirculation in sepsis

(2010) Steve M. Hollenberg   INTENSIVE CARE MEDICINE

An Antiinflammatory and Reactive Oxygen Species Suppressive Effects of an Extract ofPolygonum CuspidatumContaining Resveratrol

(2010) Husam Ghanim et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

High-sodium diet promotes a profibrogenic reaction in normal rat kidneys: effects of Tempol administration

(2010) María Inés Rosón et al.   JOURNAL OF NEPHROLOGY

Resveratrol improves cardiovascular function and reduces oxidative organ damage in the renal, cardiovascular and cerebral tissues of two-kidney, one-clip hypertensive rats

(2010) Hale Z. Toklu et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure

(2010) R.H.X. Wong et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Actinonin, a Meprin a Inhibitor, Protects the Renal Microcirculation During Sepsis

(2010) Zhen Wang et al.   SHOCK

Human catalase: looking for complete identity

(2010) Madhur M. Goyal et al.   Protein & Cell

Resveratrol Prevents the Development of Pathological Cardiac Hypertrophy and Contractile Dysfunction in the SHR Without Lowering Blood Pressure

(2009) S. J. Thandapilly et al.   AMERICAN JOURNAL OF HYPERTENSION

Nebivolol Reduces Proteinuria and Renal NADPH Oxidase-Generated Reactive Oxygen Species in the Transgenic Ren2 Rat

(2009) Adam Whaley-Connell et al.   AMERICAN JOURNAL OF NEPHROLOGY

Resveratrol: Its Biologic Targets and Functional Activity

(2009) Shazib Pervaiz et al.   ANTIOXIDANTS & REDOX SIGNALING

Resveratrol Prevents the Prohypertrophic Effects of Oxidative Stress on LKB1

(2009) Vernon W. Dolinsky et al.   CIRCULATION

Sympathoexcitation by Oxidative Stress in the Brain Mediates Arterial Pressure Elevation in Obesity-Induced Hypertension

(2009) Ai Nagae et al.   CIRCULATION

Microcirculatory Dysfunction in Sepsis

(2009) David J. Lundy et al.   CRITICAL CARE CLINICS

Molecular mechanisms of hypertension: role of Nox family NADPH oxidases

(2009) Mona Sedeek et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Current computational models do not reveal the importance of the nervous system in long-term control of arterial pressure

(2009) John W. Osborn et al.   EXPERIMENTAL PHYSIOLOGY

Attenuation of Angiotensin II–Induced Vascular Dysfunction and Hypertension by Overexpression of Thioredoxin 2

(2009) Julian D. Widder et al.   HYPERTENSION

Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study

(2009) Henry Krum et al.   LANCET

Microinjection of resveratrol into rostral ventrolateral medulla decreases sympathetic vasomotor tone through nitric oxide and intracellular Ca2+in anesthetized male rats1

(2008) Hui-juan MA et al.   ACTA PHARMACOLOGICA SINICA

Asymmetric dimethylarginine, oxidative stress, and vascular nitric oxide synthase in essential hypertension

(2008) Dan Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Redox Signaling, Vascular Function, and Hypertension

(2008) Moo Yeol Lee et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Control of Endothelial Function and Dysfunction: Molecular Mechanisms and Therapeutic Opportunities

(2008) Shane R. Thomas et al.   ANTIOXIDANTS & REDOX SIGNALING

The chemistry of cell signaling by reactive oxygen and nitrogen species and 4-hydroxynonenal

(2008) Henry Jay Forman et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

SIRT1, a Longevity Gene, Downregulates Angiotensin II Type 1 Receptor Expression in Vascular Smooth Muscle Cells

(2008) Ryohei Miyazaki et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The role of arterial smooth muscle in vasorelaxation

(2008) Igor B. Buchwalow et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Emerging potential of thioredoxin and thioredoxin interacting proteins in various disease conditions

(2008) Nilanjana Maulik et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The molecular sources of reactive oxygen species in hypertension

(2008) Paolo Puddu et al.   BLOOD PRESSURE

Resveratrol reduces endothelial progenitor cells senescence through augmentation of telomerase activity by Akt-dependent mechanisms

(2008) L Xia et al.   BRITISH JOURNAL OF PHARMACOLOGY

NADPH oxidaseCYBApolymorphisms, oxidative stress and cardiovascular diseases

(2008) Gorka San José et al.   CLINICAL SCIENCE

Mammalian xanthine oxidoreductase - mechanism of transition from xanthine dehydrogenase to xanthine oxidase

(2008) Tomoko Nishino et al.   FEBS Journal

Renal Medullary Oxidative Stress, Pressure-Natriuresis, and Hypertension

(2008) Allen W. Cowley   HYPERTENSION

Resistant Hypertension: Diagnosis, Evaluation, and Treatment

(2008) David A. Calhoun et al.   HYPERTENSION

High Salt Intake Enhances Blood Pressure Increase during Development of Hypertension via Oxidative Stress in Rostral Ventrolateral Medulla of Spontaneously Hypertensive Rats

(2008) Yasuaki Koga et al.   HYPERTENSION RESEARCH

Resveratrol: One molecule, many targets

(2008) Luciano Pirola et al.   IUBMB LIFE

Resveratrol enhances GLUT-4 translocation to the caveolar lipid raft fractions through AMPK/Akt/eNOS signalling pathway in diabetic myocardium

(2008) S. Varma Penumathsa et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

RETRACTED: Resveratrol, a unique phytoalexin present in red wine, delivers either survival signal or death signal to the ischemic myocardium depending on dose

(2008) Jocelyn Dudley et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

A Role of Ion Channels in the Endothelium-Independent Relaxation of Rat Mesenteric Artery Induced by Resveratrol

(2008) Ljiljana Gojkovic-Bukarica et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Female Rats Fed a High-Fat Diet Were Associated with Vascular Dysfunction and Cardiac Fibrosis in the Absence of Overt Obesity and Hyperlipidemia: Therapeutic Potential of Resveratrol

(2008) M.-C. Aubin et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Candesartan suppresses chronic renal inflammation by a novel antioxidant action independent of AT1R blockade

(2008) Shan Chen et al.   KIDNEY INTERNATIONAL

Global burden of blood-pressure-related disease, 2001

(2008) Carlene MM Lawes et al.   LANCET

Endothelin-1 and F2-isoprostane relate to and predict renal dysfunction in hypertensive patients

(2008) S. Cottone et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Effects of dietary polyphenols on gene expression in human vascular endothelial cells

(2008) Sonja K. Nicholson et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Oxidative stress in vascular disease: causes, defense mechanisms and potential therapies

(2008) Ulrich Förstermann   Nature clinical practice. Cardiovascular medicine

Dose-related effects of red wine and alcohol on hemodynamics, sympathetic nerve activity, and arterial diameter

(2007) Jonas Spaak et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Resveratrol Reverses Hydrogen Peroxide-induced Proliferative Effects in Human Coronary Smooth Muscle Cells: A Novel Signaling Mechanism

(2007) Abdalla M. El-Mowafy et al.   ARCHIVES OF MEDICAL RESEARCH

Molecular Mechanisms of Angiotensin II–Mediated Mitochondrial Dysfunction

(2007) Abdulrahman K. Doughan et al.   CIRCULATION RESEARCH

RETRACTED: Redox regulation of resveratrol-mediated switching of death signal into survival signal

(2007) Samarjit Das et al.   FREE RADICAL BIOLOGY AND MEDICINE

New insights into mechanism for the effect of resveratrol preconditioning against cerebral ischemic stroke: Possible role of matrix metalloprotease-9

(2007) Wenpeng Dong et al.   MEDICAL HYPOTHESES