Clinically approved IVIg delivered to the hippocampus with focused ultrasound promotes neurogenesis in a model of Alzheimer’s disease
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Clinically approved IVIg delivered to the hippocampus with focused ultrasound promotes neurogenesis in a model of Alzheimer’s disease
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 117, Issue 51, Pages 32691-32700
Publisher
Proceedings of the National Academy of Sciences
Online
2020-12-08
DOI
10.1073/pnas.1908658117
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Focused ultrasound delivery of a selective TrkA agonist rescues cholinergic function in a mouse model of Alzheimer’s disease
- (2020) K. Xhima et al. Science Advances
- Noninvasive hippocampal blood−brain barrier opening in Alzheimer’s disease with focused ultrasound
- (2020) Ali R. Rezai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Applications of focused ultrasound in the brain: from thermoablation to drug delivery
- (2020) Ying Meng et al. Nature Reviews Neurology
- Evaluating the safety profile of focused ultrasound and microbubble-mediated treatments to increase blood-brain barrier permeability
- (2019) Dallan McMahon et al. Expert Opinion on Drug Delivery
- Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease
- (2019) Elena P. Moreno-Jiménez et al. NATURE MEDICINE
- Intravenous Immunoglobulin for Patients With Alzheimer’s Disease: A Systematic Review and Meta-Analysis
- (2019) Apostolos Manolopoulos et al. American Journal of Alzheimers Disease and Other Dementias
- Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer’s Disease Patients
- (2019) Matthew K. Tobin et al. Cell Stem Cell
- Ultrasound-mediated blood-brain barrier opening enhances delivery of therapeutically relevant formats of a tau-specific antibody
- (2019) Phillip W. Janowicz et al. Scientific Reports
- Glymphatics visualization after focused ultrasound induced blood‐brain barrier opening in humans
- (2019) Ying Meng et al. ANNALS OF NEUROLOGY
- Safety and efficacy of focused ultrasound induced blood-brain barrier opening, an integrative review of animal and human studies
- (2019) Ying Meng et al. JOURNAL OF CONTROLLED RELEASE
- Tau-Reactive Endogenous Antibodies: Origin, Functionality, and Implications for the Pathophysiology of Alzheimer’s Disease
- (2019) Lenka Hromadkova et al. Journal of Immunology Research
- Next-generation Fc receptor–targeting biologics for autoimmune diseases
- (2019) Adrian W. Zuercher et al. AUTOIMMUNITY REVIEWS
- Scanning ultrasound in the absence of blood-brain barrier opening is not sufficient to clear β-amyloid plaques in the APP23 mouse model of Alzheimer's disease
- (2019) Gerhard Leinenga et al. BRAIN RESEARCH BULLETIN
- First-in-human trial of blood–brain barrier opening in amyotrophic lateral sclerosis using MR-guided focused ultrasound
- (2019) Agessandro Abrahao et al. Nature Communications
- Focused ultrasound-induced blood-brain barrier opening improves adult hippocampal neurogenesis and cognitive function in a cholinergic degeneration dementia rat model
- (2019) Jaewoo Shin et al. Alzheimers Research & Therapy
- 2018 Alzheimer's disease facts and figures
- (2018) Alzheimers & Dementia
- A Novel Therapeutic Approach to Treat Alzheimer’s Disease by Neurotrophic Support During the Period of Synaptic Compensation
- (2018) Narjes Baazaoui et al. JOURNAL OF ALZHEIMERS DISEASE
- Passive Serum Therapy to Immunomodulation by IVIG: A Fascinating Journey of Antibodies
- (2018) Cristina João et al. JOURNAL OF IMMUNOLOGY
- Blood–brain barrier opening in Alzheimer’s disease using MR-guided focused ultrasound
- (2018) Nir Lipsman et al. Nature Communications
- Safety and Efficacy of Scanning Ultrasound Treatment of Aged APP23 Mice
- (2018) Gerhard Leinenga et al. Frontiers in Neuroscience
- Hippocampal GABAergic Neurons are Susceptible to Amyloid-β Toxicity in vitro and are Decreased in Number in the Alzheimer's Disease TgCRND8 Mouse Model
- (2018) Slavica Krantic et al. JOURNAL OF ALZHEIMERS DISEASE
- βCTF-Correlated Burst of Hippocampal TNFα Occurs at a Very Early, Pre-Plaque Stage in the TgCRND8 Mouse Model of Alzheimer's Disease
- (2018) Chelsea Cavanagh et al. JOURNAL OF ALZHEIMERS DISEASE
- MRI and histological evaluation of pulsed focused ultrasound and microbubbles treatment effects in the brain
- (2018) Zsofia I Kovacs et al. Theranostics
- Association of blood IgG with tumor necrosis factor-alpha and clinical course of chronic lymphocytic leukemia
- (2018) David E. Spaner et al. EBioMedicine
- Update on the use of immunoglobulin in human disease: A review of evidence
- (2017) Elena E. Perez et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Amyloid β Plaque Reduction With Antibodies Crossing the Blood-Brain Barrier, Which Was Opened in 3 Sessions of Focused Ultrasound in a Rabbit Model
- (2017) Tereza Alecou et al. JOURNAL OF ULTRASOUND IN MEDICINE
- Blood-Brain Barrier Closure Time After Controlled Ultrasound-Induced Opening Is Independent of Opening Volume
- (2017) Meaghan A. O'Reilly et al. JOURNAL OF ULTRASOUND IN MEDICINE
- A phase 3 trial of IV immunoglobulin for Alzheimer disease
- (2017) Norman R. Relkin et al. NEUROLOGY
- Disrupting the blood–brain barrier with focused ultrasound: Perspectives on inflammation and regeneration
- (2017) Joseph Silburt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Acute Inflammatory Response Following Increased Blood-Brain Barrier Permeability Induced by Focused Ultrasound is Dependent on Microbubble Dose
- (2017) Dallan McMahon et al. Theranostics
- Investigation of the Safety of Focused Ultrasound-Induced Blood-Brain Barrier Opening in a Natural Canine Model of Aging
- (2017) Meaghan Anne O'Reilly et al. Theranostics
- On the Run for Hippocampal Plasticity
- (2017) C’iana Cooper et al. Cold Spring Harbor Perspectives in Medicine
- Phenotypic Alterations in Hippocampal NPY- and PV-Expressing Interneurons in a Presymptomatic Transgenic Mouse Model of Alzheimer’s Disease
- (2017) Ian Mahar et al. Frontiers in Aging Neuroscience
- Acute effects of focused ultrasound-induced increases in blood-brain barrier permeability on rat microvascular transcriptome
- (2017) Dallan McMahon et al. Scientific Reports
- Editorial (Thematic Issue: From Current Diagnostic Tools and Therapeutics for Alzheimer's Disease Towards Earlier Diagnostic Markers and Treatment Targets)
- (2016) Slavica Krantic Current Alzheimer Research
- A Comparative Study Evaluating the Impact of Physical Exercise on Disease Progression in a Mouse Model of Alzheimer’s Disease
- (2016) Ewelina Maliszewska-Cyna et al. JOURNAL OF ALZHEIMERS DISEASE
- From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery
- (2016) William A. Banks NATURE REVIEWS DRUG DISCOVERY
- Inhibiting tumor necrosis factor-α before amyloidosis prevents synaptic deficits in an Alzheimer's disease model
- (2016) Chelsea Cavanagh et al. NEUROBIOLOGY OF AGING
- Early alterations in blood and brain RANTES and MCP-1 expression and the effect of exercise frequency in the 3xTg-AD mouse model of Alzheimer’s disease
- (2016) Morgan Haskins et al. NEUROSCIENCE LETTERS
- Disrupting the blood–brain barrier by focused ultrasound induces sterile inflammation
- (2016) Zsofia I. Kovacs et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Focused Ultrasound-Induced Neurogenesis Requires an Increase in Blood-Brain Barrier Permeability
- (2016) Skyler J. Mooney et al. PLoS One
- Immunotherapies in Alzheimer’s disease: Too much, too little, too late or off-target?
- (2015) Isabelle St-Amour et al. ACTA NEUROPATHOLOGICA
- IVIG treatment of mild cognitive impairment due to Alzheimer's disease: a randomised double-blinded exploratory study of the effect on brain atrophy, cognition and conversion to dementia
- (2015) Shawn Kile et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Intravenous immunoglobulin in neurology—mode of action and clinical efficacy
- (2015) Jan D. Lünemann et al. Nature Reviews Neurology
- Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer’s disease mouse model
- (2015) Gerhard Leinenga et al. Science Translational Medicine
- The role of inflammatory cytokines as key modulators of neurogenesis
- (2015) Alessandra Borsini et al. TRENDS IN NEUROSCIENCES
- Peripheral Administration of Tumor Necrosis Factor-Alpha Induces Neuroinflammation and Sickness but Not Depressive-Like Behavior in Mice
- (2015) Steven Biesmans et al. Biomed Research International
- The targeting accuracy of a preclinical MRI-guided focused ultrasound system
- (2015) N. P. K. Ellens et al. MEDICAL PHYSICS
- Stimulation of Hippocampal Neurogenesis by Transcranial Focused Ultrasound and Microbubbles in Adult Mice
- (2014) Tiffany Scarcelli et al. Brain Stimulation
- Intravenous Immunoglobulin Reduces Tau Pathology and Preserves Neuroplastic Gene Expression in the 3xTg Mouse Model of Alzheimer’s Disease
- (2014) Scott Counts et al. Current Alzheimer Research
- Clinical Trials of Intravenous Immunoglobulin for Alzheimer’s Disease
- (2014) Norman Relkin JOURNAL OF CLINICAL IMMUNOLOGY
- Analysis of focused ultrasound-induced blood–brain barrier permeability in a mouse model of Alzheimer's disease using two-photon microscopy
- (2014) Alison Burgess et al. JOURNAL OF CONTROLLED RELEASE
- Predicting therapeutic efficacy of intravenous immunoglobulin (IVIG) in individual patients with relapsing remitting multiple sclerosis (RRMS) by functional genomics
- (2014) Thomas Berger et al. JOURNAL OF NEUROIMMUNOLOGY
- IVIg protects the 3xTg-AD mouse model of Alzheimer’s disease from memory deficit and Aβ pathology
- (2014) Isabelle St-Amour et al. Journal of Neuroinflammation
- Alzheimer Disease in a Mouse Model: MR Imaging–guided Focused Ultrasound Targeted to the Hippocampus Opens the Blood-Brain Barrier and Improves Pathologic Abnormalities and Behavior
- (2014) Alison Burgess et al. RADIOLOGY
- Distinguishing between Exploratory and Confirmatory Preclinical Research Will Improve Translation
- (2014) Jonathan Kimmelman et al. PLOS BIOLOGY
- Dynamics of Hippocampal Neurogenesis in Adult Humans
- (2013) Kirsty L. Spalding et al. CELL
- Amyloid-β plaque reduction, endogenous antibody delivery and glial activation by brain-targeted, transcranial focused ultrasound
- (2013) Jessica F. Jordão et al. EXPERIMENTAL NEUROLOGY
- Brain Bioavailability of Human Intravenous Immunoglobulin and its Transport through the Murine Blood–Brain Barrier
- (2013) Isabelle St-Amour et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Intracranial Injection of Gammagard, a Human IVIg, Modulates the Inflammatory Response of the Brain and Lowers A in APP/PS1 Mice Along a Different Time Course than Anti-A Antibodies
- (2013) T. L. Sudduth et al. JOURNAL OF NEUROSCIENCE
- Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer's disease: a phase 2, randomised, double-blind, placebo-controlled, dose-finding trial
- (2013) Richard Dodel et al. LANCET NEUROLOGY
- IVIG immunotherapy protects against synaptic dysfunction in Alzheimer's disease through complement anaphylatoxin C5a-mediated AMPA-CREB-C/EBP signaling pathway
- (2013) Bing Gong et al. MOLECULAR IMMUNOLOGY
- A deficiency in CCR2+ monocytes: the hidden side of Alzheimer's disease
- (2013) Gaëlle Naert et al. Journal of Molecular Cell Biology
- Effects of human intravenous immunoglobulin on amyloid pathology and neuroinflammation in a mouse model of Alzheimer’s disease
- (2012) Lakshman Puli et al. Journal of Neuroinflammation
- Blood-Brain Barrier: Real-time Feedback-controlled Focused Ultrasound Disruption by Using an Acoustic Emissions–based Controller
- (2012) Meaghan A. O’Reilly et al. RADIOLOGY
- Age-related increase in amyloid plaque burden is associated with impairment in conditioned fear memory in CRND8 mouse model of amyloidosis
- (2012) Amanda Hanna et al. Alzheimers Research & Therapy
- Clearance of albumin following ultrasound-induced blood–brain barrier opening is mediated by glial but not neuronal cells
- (2011) Angelika Alonso et al. BRAIN RESEARCH
- Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo
- (2011) Paramita Chakrabarty et al. Molecular Neurodegeneration
- Intravenous Immunoglobulins as a Treatment for Alzheimerʼs Disease
- (2010) Richard Dodel et al. DRUGS
- Human intravenous immunoglobulin provides protection against Aβ toxicity by multiple mechanisms in a mouse model of Alzheimer's disease
- (2010) Johanna Magga et al. Journal of Neuroinflammation
- Object recognition memory and BDNF expression are reduced in young TgCRND8 mice
- (2010) Beverly M. Francis et al. NEUROBIOLOGY OF AGING
- Antibodies Targeted to the Brain with Image-Guided Focused Ultrasound Reduces Amyloid-β Plaque Load in the TgCRND8 Mouse Model of Alzheimer's Disease
- (2010) Jessica F. Jordão et al. PLoS One
- When neurogenesis encounters aging and disease
- (2010) Orly Lazarov et al. TRENDS IN NEUROSCIENCES
- A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation
- (2009) C. D. Clelland et al. SCIENCE
- Ultrasound Enhanced Delivery of Molecular Imaging and Therapeutic Agents in Alzheimer's Disease Mouse Models
- (2008) Scott B. Raymond et al. PLoS One
- Blood-Brain Barrier Disruption Induced by Focused Ultrasound and Circulating Preformed Microbubbles Appears to Be Characterized by the Mechanical Index
- (2008) Nathan McDannold et al. ULTRASOUND IN MEDICINE AND BIOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started