Distinguishing between Exploratory and Confirmatory Preclinical Research Will Improve Translation

Bringing rigour to translational medicine

(2013) David W. Howells et al.   Nature Reviews Neurology

Power failure: why small sample size undermines the reliability of neuroscience

(2013) Katherine S. Button et al.   NATURE REVIEWS NEUROSCIENCE

A Concerted Appeal for International Cooperation in Preclinical Stroke Research

(2013) Ulrich Dirnagl et al.   STROKE

Threats to Validity in the Design and Conduct of Preclinical Efficacy Studies: A Systematic Review of Guidelines for In Vivo Animal Experiments

(2013) Valerie C. Henderson et al.   PLOS MEDICINE

Registered Reports: A new publishing initiative at Cortex

(2012) Christopher D. Chambers   CORTEX

A call for transparent reporting to optimize the predictive value of preclinical research

(2012) Story C. Landis et al.   NATURE

Should preclinical studies be registered?

(2012) Jonathan Kimmelman et al.   NATURE BIOTECHNOLOGY

Replication and reproducibility in spinal cord injury research

(2011) Oswald Steward et al.   EXPERIMENTAL NEUROLOGY

Enhancing translation: Guidelines for standard pre-clinical experiments in mdx mice

(2011) Raffaella Willmann et al.   NEUROMUSCULAR DISORDERS

Publication Bias in Reports of Animal Stroke Studies Leads to Major Overstatement of Efficacy

(2010) Emily S. Sena et al.   PLOS BIOLOGY

Can Animal Models of Disease Reliably Inform Human Studies?

(2010) H. Bart van der Worp et al.   PLOS MEDICINE

Heterogeneity in Cancer: Cancer Stem Cells versus Clonal Evolution

(2009) Mark Shackleton et al.   CELL

Pain research from 1975 to 2007: A categorical and bibliometric meta-trend analysis of every Research Paper published in the journal, Pain

(2008) Jeffrey S. Mogil et al.   PAIN