A deficiency in CCR2+ monocytes: the hidden side of Alzheimer's disease

Peripheral Chemokine Receptors, Their Ligands, Cytokines and Alzheimer's Disease

(2017) Marcella Reale et al.   JOURNAL OF ALZHEIMERS DISEASE

GM-CSF Upregulated in Rheumatoid Arthritis Reverses Cognitive Impairment and Amyloidosis in Alzheimer Mice

(2017) Tim D. Boyd et al.   JOURNAL OF ALZHEIMERS DISEASE

Systemic Immune Responses in Alzheimer's Disease: In Vitro Mononuclear Cell Activation and Cytokine Production

(2017) Mariavaleria Pellicanò et al.   JOURNAL OF ALZHEIMERS DISEASE

CCR2 Mediates Homeostatic and Inflammatory Release of Gr1high Monocytes from the Bone Marrow, but Is Dispensable for Bladder Infiltration in Bacterial Urinary Tract Infection

(2014) D. R. Engel et al.   JOURNAL OF IMMUNOLOGY

Proteins in Microglial Activation - Inputs and Outputs by Subsets

(2013) Uwe-Karsten Hanisch   CURRENT PROTEIN & PEPTIDE SCIENCE

Granulocyte Colony-Stimulating Factor Attenuates Chronic Neuroinflammation in the Brain of Amyloid Precursor Protein Transgenic Mice: An Alzheimer's Disease Mouse Model

(2013) H Jiang et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Systemic immune system alterations in early stages of Alzheimer's disease

(2013) Rongzhen Zhang et al.   JOURNAL OF NEUROIMMUNOLOGY

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

(2013) Katrin Kierdorf et al.   NATURE NEUROSCIENCE

Innate Immunity in the CNS: Redefining the Relationship between the CNS and Its Environment

(2013) Antoine Lampron et al.   NEURON

Toll-like receptor 4 stimulation with the detoxified ligand monophosphoryl lipid A improves Alzheimer's disease-related pathology

(2013) J.-P. Michaud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional diversity of microglia – how heterogeneous are they to begin with?

(2013) Uwe-Karsten Hanisch   Frontiers in Cellular Neuroscience

Microglia and monocyte-derived macrophages: functionally distinct populations that act in concert in CNS plasticity and repair

(2013) Anat London et al.   Frontiers in Cellular Neuroscience

Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and function

(2012) Anna C. Hearps et al.   AGING CELL

The Role of Microglial Cell Subsets in Alzheimers Disease

(2012) G. Naert et al.   Current Alzheimer Research

Inflammatory Monocytes Activate Memory CD8+ T and Innate NK Lymphocytes Independent of Cognate Antigen during Microbial Pathogen Invasion

(2012) Saïdi M'Homa Soudja et al.   IMMUNITY

CCL2 disrupts the adherens junction: implications for neuroinflammation

(2012) Toni K Roberts et al.   LABORATORY INVESTIGATION

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(2012) Gaelle Naert et al.   MOLECULAR MEDICINE

Innate Immunity and the Etiology of Late-Onset Alzheimer’s Disease

(2012) Piet Eikelenboom et al.   Neurodegenerative Diseases

Neuroinflammation: A Common Pathway in CNS Diseases as Mediated at the Blood-Brain Barrier

(2012) Michelle A. Erickson et al.   NEUROIMMUNOMODULATION

CCL2 Is Associated with a Faster Rate of Cognitive Decline during Early Stages of Alzheimer's Disease

(2012) Karin Westin et al.   PLoS One

Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells

(2012) N. H. Varvel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leukocyte CCR2 Expression Is Associated with Mini-Mental State Examination Score in Older Adults

(2012) Lorna W. Harries et al.   REJUVENATION RESEARCH

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

Age-related changes in synaptic markers and monocyte subsets link the cognitive decline of APPSwe/PS1 mice

(2012) Gaëlle Naert et al.   Frontiers in Cellular Neuroscience

The Fractalkine Receptor but Not CCR2 Is Present on Microglia from Embryonic Development throughout Adulthood

(2011) M. Mizutani et al.   JOURNAL OF IMMUNOLOGY

Immune profiling of Alzheimer patients

(2011) Mariavaleria Pellicanò et al.   JOURNAL OF NEUROIMMUNOLOGY

CC Chemokine Receptor 2 Deficiency Aggravates Cognitive Impairments and Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease

(2011) G. Naert et al.   JOURNAL OF NEUROSCIENCE

Distinct and Non-Redundant Roles of Microglia and Myeloid Subsets in Mouse Models of Alzheimer's Disease

(2011) A. Mildner et al.   JOURNAL OF NEUROSCIENCE

MyD88-adaptor protein acts as a preventive mechanism for memory deficits in a mouse model of Alzheimer's disease

(2011) Jean-Philippe Michaud et al.   Molecular Neurodegeneration

Stem cell factor and granulocyte colony-stimulating factor reduce β-amyloid deposits in the brains of APP/PS1 transgenic mice

(2011) Bin Li et al.   Alzheimers Research & Therapy

Nomenclature of monocytes and dendritic cells in blood

(2010) L. Ziegler-Heitbrock et al.   BLOOD

Age-dependent alterations of monocyte subsets and monocyte-related chemokine pathways in healthy adults

(2010) Sebastian Seidler et al.   BMC IMMUNOLOGY

Impaired Functions of Peripheral Blood Monocyte Subpopulations in Aged Humans

(2010) Joseph Nyugen et al.   JOURNAL OF CLINICAL IMMUNOLOGY

CCR2 mediates hematopoietic stem and progenitor cell trafficking to sites of inflammation in mice

(2010) Yue Si et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases

(2010) Grégory Conductier et al.   JOURNAL OF NEUROIMMUNOLOGY

Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice

(2010) Noah Saederup et al.   PLoS One

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Blood Monocytes: Development, Heterogeneity, and Relationship with Dendritic Cells

(2009) Cedric Auffray et al.   Annual Review of Immunology

Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease

(2009) I. L. King et al.   BLOOD

Powerful beneficial effects of macrophage colony-stimulating factor on  -amyloid deposition and cognitive impairment in Alzheimer's disease

(2009) V. Boissonneault et al.   BRAIN

CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system

(2009) Alexander Mildner et al.   BRAIN

CX3CR1+CD115+CD135+common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation

(2009) Cedric Auffray et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Monocyte Chemoattractant Protein-1 (MCP-1): An Overview

(2009) Satish L. Deshmane et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Cerebral Microglia Recruit Monocytes into the Brain in Response to Tumor Necrosis Factor  Signaling during Peripheral Organ Inflammation

(2009) C. D'Mello et al.   JOURNAL OF NEUROSCIENCE

AAV1/2-mediated CNS Gene Delivery of Dominant-negative CCL2 Mutant Suppresses Gliosis, β-amyloidosis, and Learning Impairment of APP/PS1 Mice

(2009) Tomomi Kiyota et al.   MOLECULAR THERAPY

Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia

(2009) Stefan A Grathwohl et al.   NATURE NEUROSCIENCE

Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway

(2009) Vanja Vukic et al.   NEUROBIOLOGY OF DISEASE

Granulocyte colony stimulating factor decreases brain amyloid burden and reverses cognitive impairment in Alzheimer's mice

(2009) J. Sanchez-Ramos et al.   NEUROSCIENCE

CCL2 Accelerates Microglia-Mediated Aβ Oligomer Formation and Progression of Neurocognitive Dysfunction

(2009) Tomomi Kiyota et al.   PLoS One

Microglia

(2008) Denis Soulet et al.   CURRENT BIOLOGY

Bone-marrow-derived microglia: myth or reality?

(2008) Denis Soulet et al.   CURRENT OPINION IN PHARMACOLOGY

The granulocyte macrophage colony stimulating factor (GM-CSF) regulates amyloid β (Aβ) production

(2008) Claude-Henry Volmar et al.   CYTOKINE

Blood monocytes: distinct subsets, how they relate to dendritic cells, and their possible roles in the regulation of T-cell responses

(2008) Frederic Geissmann et al.   IMMUNOLOGY AND CELL BIOLOGY

Ly6c+“inflammatory monocytes” are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis

(2008) Daniel R. Getts et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunophenotypes in the circulation of patients with mild cognitive impairment

(2007) Shino Magaki et al.   JOURNAL OF PSYCHIATRIC RESEARCH