Quercetin: Its Main Pharmacological Activity and Potential Application in Clinical Medicine

The Effects and Mechanism of Quercetin Dietary Supplementation in Streptozotocin-Induced Hyperglycemic Arbor Acre Broilers

(2020) Linlin Ying et al.   Oxidative Medicine and Cellular Longevity

Evaluation of Neuroprotective Effects of Quercetin against Aflatoxin B1-Intoxicated Mice

(2020) Enrico Gugliandolo et al.   Animals

Demonstration of bactericidal and synergistic activity of quercetin with meropenem among pathogenic carbapenem resistant Escherichia coli and Klebsiella pneumoniae

(2020) Arijit Pal et al.   MICROBIAL PATHOGENESIS

Quercetin Inhibits the Proliferation and Aflatoxins Biosynthesis of Aspergillus flavus

(2019) Xiu-Mei Li et al.   Toxins

Antioxidant Activities of Quercetin and Its Complexes for Medicinal Application

(2019) Dong Xu et al.   MOLECULES

Anti‐biofilm and cytoprotective activities of quercetin against Pseudomonas aeruginosa isolates

(2019) C. Vipin et al.   LETTERS IN APPLIED MICROBIOLOGY

Quercetin inhibits human metastatic ovarian cancer cell growth and modulates components of the intrinsic apoptotic pathway in PA-1 cell line

(2019) Dhanaraj Teekaraman et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Antifungal effects of the flavonoids kaempferol and quercetin: a possible alternative for the control of fungal biofilms

(2019) Marcos Fábio Gadelha Rocha et al.   BIOFOULING

Precise Modeling of the Protective Effects of Quercetin against Mycotoxin via System Identification with Neural Networks

(2019) Changju Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Quercetin protects rats from catheter‐related Staphylococcus aureus infections by inhibiting coagulase activity

(2019) Lin Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Identification and evaluation of quercetin as a potential inhibitor of naphthoate synthase from Enterococcus faecalis

(2019) Satyajeet Das et al.   JOURNAL OF MOLECULAR RECOGNITION

Modulation of aflatoxin B1 cytotoxicity and aflatoxin M1 synthesis by natural antioxidants in a bovine mammary epithelial cell line

(2019) Shiva Ghadiri et al.   TOXICOLOGY IN VITRO

Preparation of Quercetin Esters and Their Antioxidant Activity

(2019) Won Young Oh et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Quercetin potentiates meropenem activity among pathogenic carbapenem‐resistant Pseudomonas aeruginosa and Acinetobacter baumannii

(2019) A. Pal et al.   JOURNAL OF APPLIED MICROBIOLOGY

Potential Therapeutic Targets of Quercetin and Its Derivatives: Its Role in the Therapy of Cognitive Impairment

(2019) Jakaria et al.   Journal of Clinical Medicine

The Effect of Dihydroquercetin on Catalytic Activity of Iron (II) Ions in the Fenton Reaction

(2018) I. V. Babenkova et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

In vitro effects of diosmin, naringenin, quercetin and indole-3-carbinol on fish hepatic CYP1A1 in the presence of clotrimazole and dexamethasone

(2018) Sidika Sakalli et al.   CHEMOSPHERE

Ochratoxin A: Toxicity, oxidative stress and metabolism

(2018) Yanfei Tao et al.   FOOD AND CHEMICAL TOXICOLOGY

Quercetin reduces adhesion and inhibits biofilm development by Listeria monocytogenes by reducing the amount of extracellular proteins

(2018) F.J. Vazquez-Armenta et al.   FOOD CONTROL

Bacteriostatic Effect of Quercetin as an Antibiotic Alternative In Vivo and Its Antibacterial Mechanism In Vitro

(2018) Shengan Wang et al.   JOURNAL OF FOOD PROTECTION

Quercetin exerts cardiovascular protective effects in LPS-induced dysfunction in vivo by regulating inflammatory cytokine expression, NF-κB phosphorylation, and caspase activity

(2018) Xiqing Wei et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Structure-Dependent Modulation of Aryl Hydrocarbon Receptor-Mediated Activities by Flavonoids

(2018) Un-Ho Jin et al.   TOXICOLOGICAL SCIENCES

Quercetin 3-O-glucoside recovered from the wild Egyptian Sahara plant, Euphorbia paralias L., inhibits glutamine synthetase and has antimycobacterial activity

(2018) Nesreen A. Safwat et al.   TUBERCULOSIS

Quercetin increases the antioxidant capacity of the ovary in menopausal rats and in ovarian granulosa cell culture in vitro

(2018) Jiao Wang et al.   Journal of Ovarian Research

Quercetin from Shallots (Allium cepa L. var. aggregatum) Is More Bioavailable Than Its Glucosides

(2018) Wieslaw Wiczkowski et al.   JOURNAL OF NUTRITION

Abrasive treatment of microtiter plates improves the reproducibility of bacterial biofilm assays

(2018) Emily Bordeleau et al.   RSC Advances

In Vitro Synergism and Anti-biofilm Activity of Quercetin–Pivaloxymethyl Conjugate against Staphylococcus aureus and Enterococcus Species

(2018) Mi Kyoung Kim et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Can plant phenolic compounds reduce Fusarium growth and mycotoxin production in cereals?

(2018) Torsten Schöneberg et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Quercetin impairs Streptococcus pneumoniae biofilm formation by inhibiting sortase A activity

(2018) Jianfeng Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Identification of factors involved in Enterococcus faecalis biofilm under quercetin stress

(2018) Shariq Qayyum et al.   MICROBIAL PATHOGENESIS

Activity of quercetin and kaemferol against Streptococcus mutans biofilm

(2018) Yan Zeng et al.   ARCHIVES OF ORAL BIOLOGY

Quercetin inhibits swarming motility and activates biofilm production of Proteus mirabilis possibly by interacting with central regulators, metabolic status or active pump proteins

(2018) Abdurrahman Aygül et al.   PHYTOMEDICINE

Characterization of the Effects of the Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes), on Severe Gestational Diabetes Mellitus in Rats

(2017) Bianca Hessel Maschio et al.   INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS

Biosynthesis, Characterization of Silver Nanoparticles Using Quercetin from Clitoria ternatea L to Enhance Toxicity Against Bacterial Biofilm

(2017) Sekar Vanaraj et al.   Journal of Inorganic and Organometallic Polymers and Materials

Quercetin loading CdSe/ZnS nanoparticles as efficient antibacterial and anticancer materials

(2017) Xiaofang Yang et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways

(2017) Marisa Granato et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The Beneficial Effects of Quercetin, Curcumin, and Resveratrol in Obesity

(2017) Yueshui Zhao et al.   Oxidative Medicine and Cellular Longevity

High-performance therapeutic quercetin-doped adhesive for adhesive–dentin interfaces

(2017) Hongye Yang et al.   Scientific Reports

The Influence of Quercetin on Maternal Immunity, Oxidative Stress, and Inflammation in Mice with Exposure of Fine Particulate Matter during Gestation

(2017) Wei Liu et al.   International Journal of Environmental Research and Public Health

Hepatoprotective and free radical scavenging actions of quercetin nanoparticles on aflatoxin B1-induced liver damage: in vitro/in vivo studies

(2017) Aziz Eftekhari et al.   Artificial Cells Nanomedicine and Biotechnology

Effect of Naringenin, Quercetin, and Sesamin on Xenobiotica-Metabolizing CYP1A and CYP3A in Mice Offspring after Maternal Exposure to Persistent Organic Pollutants

(2017) Nadezhda Pilipenko et al.   Biomed Research International

Bioactive effects of quercetin in the central nervous system: Focusing on the mechanisms of actions

(2016) Natarajan Suganthy et al.   BIOMEDICINE & PHARMACOTHERAPY

Quercetin and rutin as potential agents antifungal against Cryptococcus spp

(2016) V. M. Oliveira et al.   BRAZILIAN JOURNAL OF BIOLOGY

Quercetin Assists Fluconazole to Inhibit Biofilm Formations of Fluconazole-Resistant Candida Albicans in In Vitro and In Vivo Antifungal Managements of Vulvovaginal Candidiasis

(2016) Mei Gao et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Acute intake of quercetin from onion skin extract does not influence postprandial blood pressure and endothelial function in overweight-to-obese adults with hypertension: a randomized, double-blind, placebo-controlled, crossover trial

(2016) Verena Brüll et al.   EUROPEAN JOURNAL OF NUTRITION

Metabolism of Quercetin and Naringenin by Food-Grade Fungal Inoculum, Rhizopus azygosporus Yuan et Jong (ATCC 48108)

(2016) Gerard Bryan Gonzales et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Synthesis and cardiovascular protective effects of quercetin 7-O-sialic acid

(2016) Hua Tian et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Therapeutic Effects of Quercetin on Inflammation, Obesity, and Type 2 Diabetes

(2016) Shuang Chen et al.   MEDIATORS OF INFLAMMATION

Quercetin and Its Anti-Allergic Immune Response

(2016) Jiri Mlcek et al.   MOLECULES

Activation of ER stress and apoptosis by α- and β-zearalenol in HCT116 cells, protective role of Quercetin

(2016) Intidhar Ben Salem et al.   NEUROTOXICOLOGY

Quercetin induces caspase-dependent extrinsic apoptosis through inhibition of signal transducer and activator of transcription 3 signaling in HER2-overexpressing BT-474 breast cancer cells

(2016) HYE-SOOK SEO et al.   ONCOLOGY REPORTS

Quercetin, Inflammation and Immunity

(2016) Yao Li et al.   Nutrients

Quercetin Sensitizes Fluconazole-Resistant Candida albicans To Induce Apoptotic Cell Death by Modulating Quorum Sensing

(2015) B. N. Singh et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Quercetin-6-C-β-d-glucopyranoside, natural analog of quercetin exhibits anti-prostate cancer activity by inhibiting Akt-mTOR pathway via aryl hydrocarbon receptor

(2015) Hamidullah et al.   BIOCHIMIE

Crocin and Quercetin protect HCT116 and HEK293 cells from Zearalenone-induced apoptosis by reducing endoplasmic reticulum stress

(2015) Intidhar Ben Salem et al.   CELL STRESS & CHAPERONES

Cardiovascular Disease: A Target for the Pharmacological Effects of Quercetin

(2015) Juan Gormaz et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Oxidative stress and brain mitochondria swelling induced by endosulfan and protective role of quercetin in rat

(2015) Zhoura Lakroun et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Natural products as inhibitors of recombinant cathepsin L of Leishmania mexicana

(2015) Lorena R.F. de Sousa et al.   EXPERIMENTAL PARASITOLOGY

Quercetin: A flavonol with multifaceted therapeutic applications?

(2015) Gabriele D'Andrea   FITOTERAPIA

Sodium tungstate induced neurological alterations in rat brain regions and their response to antioxidants

(2015) Sherry Sachdeva et al.   FOOD AND CHEMICAL TOXICOLOGY

The antibiotic activity and mechanisms of sugarcane (Saccharum officinarum L.) bagasse extract against food-borne pathogens

(2015) Yi Zhao et al.   FOOD CHEMISTRY

Synthesis, characterization and study of antioxidant activity of quercetin–magnesium complex

(2015) Nilanjan Ghosh et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Chronic high intake of quercetin reduces oxidative stress and induces expression of the antioxidant enzymes in the liver and visceral adipose tissues in mice

(2015) Masuko Kobori et al.   Journal of Functional Foods

In VitroGender-Dependent Inhibition of Porcine Cytochrome P450 Activity by Selected Flavonoids and Phenolic Acids

(2015) Bo Ekstrand et al.   Biomed Research International

Plant-derived immunomodulators: an insight on their preclinical evaluation and clinical trials

(2015) Ibrahim Jantan et al.   Frontiers in Plant Science

Red wines and flavonoids diminishStaphylococcus aureusvirulence with anti-biofilm and anti-hemolytic activities

(2014) Hyun Seob Cho et al.   BIOFOULING

Improvement of quercetin protective effect against oxidative stress skin damages by incorporation in nanovesicles

(2014) Maria Letizia Manca et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Quercetin protects human peripheral blood mononuclear cells from OTA-induced oxidative stress, genotoxicity, and inflammation

(2014) Ramyaa Periasamy et al.   ENVIRONMENTAL TOXICOLOGY

Quercetin attenuates chronic ethanol hepatotoxicity: Implication of “free” iron uptake and release

(2014) Yuhan Tang et al.   FOOD AND CHEMICAL TOXICOLOGY

Quercetin Protects against Obesity-Induced Skeletal Muscle Inflammation and Atrophy

(2014) Ngoc Hoan Le et al.   MEDIATORS OF INFLAMMATION

Effects of dietary supplementation of quercetin on performance, egg quality, cecal microflora populations, and antioxidant status in laying hens

(2014) H. N. Liu et al.   POULTRY SCIENCE

Quercetin-3-glucoside increases low-density lipoprotein receptor (LDLR) expression, attenuates proprotein convertase subtilisin/kexin 9 (PCSK9) secretion, and stimulates LDL uptake by Huh7 human hepatocytes in culture

(2014) Majambu Mbikay et al.   FEBS Open Bio

Synergistic Effect of the Flavonoid Catechin, Quercetin, or Epigallocatechin Gallate with Fluconazole Induces Apoptosis in Candida tropicalis Resistant to Fluconazole

(2013) Cecília Rocha da Silva et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Quercetin modulates OTA-induced oxidative stress and redox signalling in HepG2 cells — up regulation of Nrf2 expression and down regulation of NF-κB and COX-2

(2013) Periasamy Ramyaa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Anti-biofilm activities of quercetin and tannic acid againstStaphylococcus aureus

(2013) Jin-Hyung Lee et al.   BIOFOULING

Ochratoxin-induced toxicity, oxidative stress and apoptosis ameliorated by quercetin – Modulation by Nrf2

(2013) Periasamy Ramyaa et al.   FOOD AND CHEMICAL TOXICOLOGY

Dietary quercetin attenuates oxidant-induced endothelial dysfunction and atherosclerosis in apolipoprotein E knockout mice fed a high-fat diet: A critical role for heme oxygenase-1

(2013) Yu Shen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of quercetin on the proliferation of breast cancer cells and expression of survivin in vitro

(2013) XIAO-HUI DENG et al.   Experimental and Therapeutic Medicine

Effect of Quercetin in the 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-Induced Mouse Model of Parkinson's Disease

(2012) Chuanfeng Lv et al.   Evidence-based Complementary and Alternative Medicine

Quercetin in Cancer Prevention and Therapy

(2012) Salvatore Chirumbolo   INTEGRATIVE CANCER THERAPIES

Antiplasmodial activity of flavonol quercetin and its analogues in Plasmodium falciparum: evidence from clinical isolates in Bangladesh and standardized parasite clones

(2012) Deepa Ganesh et al.   PARASITOLOGY RESEARCH

Protective properties of quercetin against DNA damage and oxidative stress induced by methylmercury in rats

(2011) Gustavo Rafael Mazzaron Barcelos et al.   ARCHIVES OF TOXICOLOGY

Anti-inflammatory, anti-proliferative and anti-atherosclerotic effects of quercetin in human in vitro and in vivo models

(2011) Robert Kleemann et al.   ATHEROSCLEROSIS

Quercetin modulates Nrf2 and glutathione-related defenses in HepG2 cells: Involvement of p38

(2011) Ana Belén Granado-Serrano et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Cognitive-Enhancing Effect of Quercetin in a Rat Model of Parkinson's Disease Induced by 6-Hydroxydopamine

(2011) Napatr Sriraksa et al.   Evidence-based Complementary and Alternative Medicine

Accumulation of orally administered quercetin in brain tissue and its antioxidative effects in rats

(2011) Akari Ishisaka et al.   FREE RADICAL BIOLOGY AND MEDICINE

Flavonoid Analyses and Antimicrobial Activity of Various Parts of Phaleria macrocarpa (Scheff.) Boerl Fruit

(2011) Rudi Hendra et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Assessment of the Antibacterial Activity and the Antidiarrheal Function of Flavonoids from Bayberry Fruit

(2011) Wei Rong Yao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Quercetin Diacylglycoside Analogues Showing Dual Inhibition of DNA Gyrase and Topoisomerase IV as Novel Antibacterial Agents

(2011) Abugafar M. L. Hossion et al.   JOURNAL OF MEDICINAL CHEMISTRY

Maternal quercetin intake during pregnancy results in an adapted iron homeostasis at adulthood

(2011) Kimberly Vanhees et al.   TOXICOLOGY

Induction of G1/S phase arrest and apoptosis by quercetin in human osteosarcoma cells

(2010) Doo Kyo Suh et al.   ARCHIVES OF PHARMACAL RESEARCH

Quercetin-mediated cell cycle arrest and apoptosis involving activation of a caspase cascade through the mitochondrial pathway in human breast cancer MCF-7 cells

(2010) Chu-Chung Chou et al.   ARCHIVES OF PHARMACAL RESEARCH

Pretreatment with quercetin ameliorates lipids, lipoproteins and marker enzymes of lipid metabolism in isoproterenol treated cardiotoxic male Wistar rats

(2010) Ponnian Stanely Mainzen Prince et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Effect of quercetin and its metabolites isorhamnetin and quercetin-3-glucuronide on inflammatory gene expression: role of miR-155☆

(2010) Christine Boesch-Saadatmandi et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Diverse Effects on Mitochondrial and Nuclear Functions Elicited by Drugs and Genetic Knockdowns in Bloodstream Stage Trypanosoma brucei

(2010) Christal Worthen et al.   PLoS Neglected Tropical Diseases

Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: a double-blinded, placebo-controlled cross-over study

(2009) Sarah Egert et al.   BRITISH JOURNAL OF NUTRITION

Quercetin inhibits fatty acid and triacylglycerol synthesis in rat-liver cells

(2009) G. V. Gnoni et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

The multiple faces of quercetin in neuroprotection

(2009) Bernardino Ossola et al.   Expert Opinion On Drug Safety

Effects of Quercetin and EGCG on Mitochondrial Biogenesis and Immunity

(2009) DAVID C. NIEMAN et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Isoenzyme-specific up-regulation of glutathione transferase and aldo-keto reductase mRNA expression by dietary quercetin in rat liver

(2009) Tseye-Oidov Odbayar et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Inhibitory effect of quercetin on periodontal pathogensin vitro

(2009) F. Geoghegan et al.   PHYTOTHERAPY RESEARCH

Quercetin improves cognitive deficits in rats with chronic cerebral ischemia and inhibits voltage-dependent sodium channels in hippocampal CA1 pyramidal neurons

(2009) Y. Yao et al.   PHYTOTHERAPY RESEARCH

Possible use of quercetin, an antioxidant, for protection of cells suffering from overload of intracellular Ca2+: A model experiment

(2008) Yoko Sakanashi et al.   LIFE SCIENCES

Quercetin relieves chronic lead exposure-induced impairment of synaptic plasticity in rat dentate gyrus in vivo

(2008) Pu Hu et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Resveratrol and quercetin, two natural polyphenols, reduce apoptotic neuronal cell death induced by neuroinflammation

(2007) Genevieve Bureau et al.   JOURNAL OF NEUROSCIENCE RESEARCH