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Title
Organoids and organ chips in ophthalmology
Authors
Keywords
Organoid, Organ-on-a-chip, Organ chip, Microfluidics, Ophthalmology, Eye, Retina, Cornea, Lens, Lacrimal gland
Journal
Ocular Surface
Volume 19, Issue -, Pages 1-15
Publisher
Elsevier BV
Online
2020-11-19
DOI
10.1016/j.jtos.2020.11.004
References
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- (2020) Dunja Lukovic et al. Scientific Reports
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- (2020) Amelia Lane et al. Stem Cell Reports
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- Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5
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- (2019) Mostafa Heidari et al. Journal of Clinical Medicine
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- (2019) Peter M.J. Quinn et al. Genes
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- (2019) Kang-Chieh Huang et al. Stem Cell Reports
- Invertebrate Retinal Progenitors as Regenerative Models in a Microfluidic System
- (2019) Pena et al. Cells
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- (2019) Muhammad Ali et al. Scientific Reports
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- (2018) Patricia Murphy et al. DEVELOPMENT
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- (2018) Anai Gonzalez-Cordero et al. HUMAN GENE THERAPY
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- (2018) Peter M Quinn et al. HUMAN MOLECULAR GENETICS
- A compartmentalized microfluidic chip with crisscross microgrooves and electrophysiological electrodes for modeling the blood–retinal barrier
- (2018) Jose Yeste et al. LAB ON A CHIP
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- (2018) Devasier Bennet et al. LAB ON A CHIP
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- (2018) Manjit S. Mehat et al. OPHTHALMOLOGY
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- (2018) Wen-Li Deng et al. Stem Cell Reports
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- (2018) Ankush Thakur et al. Journal of Tissue Engineering
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- (2018) Adam M. Miltner et al. DEVELOPMENTAL DYNAMICS
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- (2018) Peter M Quinn et al. HUMAN MOLECULAR GENETICS
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- (2018) Clarisse M. Fligor et al. Scientific Reports
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- (2018) Duangporn Saengwimol et al. Scientific Reports
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- (2017) Qiuli Fu et al. Molecular Therapy-Nucleic Acids
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- Human Lacrimal Gland Gene Expression
- (2017) Vinay Kumar Aakalu et al. PLoS One
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- (2017) James W. Foster et al. Scientific Reports
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- (2017) Karl J. Wahlin et al. Scientific Reports
- Ageing and ocular surface immunity
- (2016) Alireza Mashaghi et al. BRITISH JOURNAL OF OPHTHALMOLOGY
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- (2016) Hans Clevers CELL
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- (2016) Tiago Santos-Ferreira et al. Nature Communications
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- (2016) Mandeep S. Singh et al. Nature Communications
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- (2016) Florencia Marcucci et al. Cell Reports
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- (2015) Lucie P. Pellissier et al. HUMAN MOLECULAR GENETICS
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- (2015) Maria H. Madeira et al. MEDIATORS OF INFLAMMATION
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- (2015) Rossukon Kaewkhaw et al. STEM CELLS
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- (2015) Kristina Spaniol et al. TISSUE ENGINEERING PART A
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- (2015) Atsushi Kuwahara et al. Nature Communications
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- (2015) Briana R Dye et al. eLife
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- (2014) Shin Lin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2014) Celso Henrique Alves et al. PROGRESS IN RETINAL AND EYE RESEARCH
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- (2013) Steven Garnier et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Unknown
- (2013) Yao Li et al. MOLECULAR MEDICINE
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- (2013) Masatoshi Hirayama et al. Nature Communications
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- (2013) Miho Ogawa et al. Nature Communications
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- (2012) Francesco Antonica et al. NATURE
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- (2012) R. A. Pearson et al. NATURE
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- (2012) Koh-ei Toyoshima et al. Nature Communications
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- (2011) Kinga Bujakowska et al. HUMAN MUTATION
- Self-organizing optic-cup morphogenesis in three-dimensional culture
- (2011) Mototsugu Eiraku et al. NATURE
- Mouse embryonic stem cell culture for generation of three-dimensional retinal and cortical tissues
- (2011) Mototsugu Eiraku et al. Nature Protocols
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- (2011) Masamitsu Oshima et al. PLoS One
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- (2011) Patrick M Chen et al. Cell and Bioscience
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- (2010) José Cunha-Vaz et al. EUROPEAN JOURNAL OF OPHTHALMOLOGY
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- (2010) Chunbo Yang et al. FASEB JOURNAL
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- (2010) Nelita T. Elliott et al. JOURNAL OF PHARMACEUTICAL SCIENCES
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- (2010) Jason R. Spence et al. NATURE
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- (2010) Nan-Kai Wang et al. TRANSPLANTATION
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- (2009) S Schrader et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Integration and application of vitrified collagen in multilayered microfluidic devices for corneal microtissue culture
- (2009) Christopher M. Puleo et al. LAB ON A CHIP
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- (2009) E.M. De Robertis MECHANISMS OF DEVELOPMENT
- Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
- (2009) Toshiro Sato et al. NATURE
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- (2009) E. Ikeda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modeling early retinal development with human embryonic and induced pluripotent stem cells
- (2009) J. S. Meyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals
- (2008) Mototsugu Eiraku et al. Cell Stem Cell
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