Generation, transcriptome profiling, and functional validation of cone-rich human retinal organoids
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Generation, transcriptome profiling, and functional validation of cone-rich human retinal organoids
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 116, Issue 22, Pages 10824-10833
Publisher
Proceedings of the National Academy of Sciences
Online
2019-05-10
DOI
10.1073/pnas.1901572116
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Molecular Classification and Comparative Taxonomics of Foveal and Peripheral Cells in Primate Retina
- (2019) Yi-Rong Peng et al. CELL
- Regenerating Eye Tissues to Preserve and Restore Vision
- (2018) Jeffrey H. Stern et al. Cell Stem Cell
- Human induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient dependent efficiency
- (2018) Dean Hallam et al. STEM CELLS
- RNA Biology in Retinal Development and Disease
- (2018) Lina Zelinger et al. TRENDS IN GENETICS
- Generation of Retinal Organoids with Mature Rods and Cones from Urine-Derived Human Induced Pluripotent Stem Cells
- (2018) Guilan Li et al. Stem Cells International
- Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines
- (2018) Elizabeth E. Capowski et al. DEVELOPMENT
- Thyroid hormone signaling specifies cone subtypes in human retinal organoids
- (2018) Kiara C. Eldred et al. SCIENCE
- Deconstructing Retinal Organoids: Single Cell RNA-Seq Reveals the Cellular Components of Human Pluripotent Stem Cell-Derived Retina
- (2018) Joseph Collin et al. STEM CELLS
- REEP6 deficiency leads to retinal degeneration through disruption of ER homeostasis and protein trafficking
- (2017) Smriti A. Agrawal et al. HUMAN MOLECULAR GENETICS
- The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis
- (2017) Issam Aldiri et al. NEURON
- A Novel Approach to Single Cell RNA-Sequence Analysis Facilitates In Silico Gene Reporting of Human Pluripotent Stem Cell-Derived Retinal Cell Types
- (2017) M. Joseph Phillips et al. STEM CELLS
- Isolation and Comparative Transcriptome Analysis of Human Fetal and iPSC-Derived Cone Photoreceptor Cells
- (2017) Emily Welby et al. Stem Cell Reports
- Photoreceptor Outer Segment-like Structures in Long-Term 3D Retinas from Human Pluripotent Stem Cells
- (2017) Karl J. Wahlin et al. Scientific Reports
- Mutations in REEP6 Cause Autosomal-Recessive Retinitis Pigmentosa
- (2016) Gavin Arno et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Comprehensive Classification of Retinal Bipolar Neurons by Single-Cell Transcriptomics
- (2016) Karthik Shekhar et al. CELL
- Identification and Correction of Mechanisms Underlying Inherited Blindness in Human iPSC-Derived Optic Cups
- (2016) David A. Parfitt et al. Cell Stem Cell
- Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown
- (2016) Mihaela Pertea et al. Nature Protocols
- Segregated Glycine-Glutamate Co-transmission from vGluT3 Amacrine Cells to Contrast-Suppressed and Contrast-Enhanced Retinal Circuits
- (2016) Seunghoon Lee et al. NEURON
- An atlas of gene expression and gene co-regulation in the human retina
- (2016) Michele Pinelli et al. NUCLEIC ACIDS RESEARCH
- Intercellular Adhesion-Dependent Cell Survival and ROCK-Regulated Actomyosin-Driven Forces Mediate Self-Formation of a Retinal Organoid
- (2016) Albert Lowe et al. Stem Cell Reports
- Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
- (2015) Evan Z. Macosko et al. CELL
- Quantification of Retinogenesis in 3D Cultures Reveals Epigenetic Memory and Higher Efficiency in iPSCs Derived from Rod Photoreceptors
- (2015) Daniel Hiler et al. Cell Stem Cell
- Photoreceptor cell fate specification in vertebrates
- (2015) Joseph A. Brzezinski et al. DEVELOPMENT
- Biology and therapy of inherited retinal degenerative disease: insights from mouse models
- (2015) Shobi Veleri et al. Disease Models & Mechanisms
- HISAT: a fast spliced aligner with low memory requirements
- (2015) Daehwan Kim et al. NATURE METHODS
- Transcriptome Dynamics of Developing Photoreceptors in Three-Dimensional Retina Cultures Recapitulates Temporal Sequence of Human Cone and Rod Differentiation Revealing Cell Surface Markers and Gene Networks
- (2015) Rossukon Kaewkhaw et al. STEM CELLS
- Regulation of a novel isoform of Receptor Expression Enhancing Protein REEP6 in rod photoreceptors by bZIP transcription factor NRL
- (2014) Hong Hao et al. HUMAN MOLECULAR GENETICS
- Comprehensive analysis of gene expression in human retina and supporting tissues
- (2014) Mingyao Li et al. HUMAN MOLECULAR GENETICS
- Intrinsically different retinal progenitor cells produce specific types of progeny
- (2014) Connie Cepko NATURE REVIEWS NEUROSCIENCE
- From confluent human iPS cells to self-forming neural retina and retinal pigmented epithelium
- (2014) S. Reichman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Organogenesis in a dish: Modeling development and disease using organoid technologies
- (2014) M. A. Lancaster et al. SCIENCE
- Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs
- (2014) Xiufeng Zhong et al. Nature Communications
- Transcriptome analyses of the human retina identify unprecedented transcript diversity and 3.5 Mb of novel transcribed sequence via significant alternative splicing and novel genes
- (2013) Michael H Farkas et al. BMC GENOMICS
- RNA-sequencing from single nuclei
- (2013) R. V. Grindberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
- (2013) Daehwan Kim et al. GENOME BIOLOGY
- Histologic Development of the Human Fovea From Midgestation to Maturity
- (2012) Anita Hendrickson et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Self-Formation of Optic Cups and Storable Stratified Neural Retina from Human ESCs
- (2012) Tokushige Nakano et al. Cell Stem Cell
- Transcriptional code and disease map for adult retinal cell types
- (2012) Sandra Siegert et al. NATURE NEUROSCIENCE
- Evolutionary Dynamics of Gene and Isoform Regulation in Mammalian Tissues
- (2012) J. Merkin et al. SCIENCE
- Self-organizing optic-cup morphogenesis in three-dimensional culture
- (2011) Mototsugu Eiraku et al. NATURE
- Optic Vesicle-like Structures Derived from Human Pluripotent Stem Cells Facilitate a Customized Approach to Retinal Disease Treatment
- (2011) Jason S. Meyer et al. STEM CELLS
- Neuroretina specification in mouse embryos requires Six3-mediated suppression of Wnt8b in the anterior neural plate
- (2010) Wei Liu et al. JOURNAL OF CLINICAL INVESTIGATION
- Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
- (2010) Cole Trapnell et al. NATURE BIOTECHNOLOGY
- Analysis and design of RNA sequencing experiments for identifying isoform regulation
- (2010) Yarden Katz et al. NATURE METHODS
- Transcriptional regulation of photoreceptor development and homeostasis in the mammalian retina
- (2010) Anand Swaroop et al. NATURE REVIEWS NEUROSCIENCE
- Low-Conductance HCN1 Ion Channels Augment the Frequency Response of Rod and Cone Photoreceptors
- (2009) A. J. Barrow et al. JOURNAL OF NEUROSCIENCE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started