Retinal Ganglion Cells With a Glaucoma OPTN(E50K) Mutation Exhibit Neurodegenerative Phenotypes when Derived from Three-Dimensional Retinal Organoids

Published 2020 View Full Article

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Title
Retinal Ganglion Cells With a Glaucoma OPTN(E50K) Mutation Exhibit Neurodegenerative Phenotypes when Derived from Three-Dimensional Retinal Organoids
Authors
Keywords
stem cell, iPSC, retina, glaucoma, autophagy, differentiation, disease, modeling, CRISPR, gene editing, neurodegeneration
Journal
Stem Cell Reports
Volume 15, Issue 1, Pages 52-66
Publisher
Elsevier BV
Online
2020-06-11
DOI
10.1016/j.stemcr.2020.05.009

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