标题
Organoids and organ chips in ophthalmology
作者
关键词
Organoid, Organ-on-a-chip, Organ chip, Microfluidics, Ophthalmology, Eye, Retina, Cornea, Lens, Lacrimal gland
出版物
Ocular Surface
Volume 19, Issue -, Pages 1-15
出版商
Elsevier BV
发表日期
2020-11-19
DOI
10.1016/j.jtos.2020.11.004
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- AAV-Mediated Gene Delivery to 3D Retinal Organoids Derived from Human Induced Pluripotent Stem Cells
- (2020) Marcela Garita-Hernandez et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Variable Responses to Corneal Grafts: Insights from Immunology and Systems Biology
- (2020) Antonio Di Zazzo et al. Journal of Clinical Medicine
- Patient-Specific Retinal Organoids Recapitulate Disease Features of Late-Onset Retinitis Pigmentosa
- (2020) Mei-Ling Gao et al. Frontiers in Cell and Developmental Biology
- Retinal Organoids derived from hiPSCs of an AIPL1-LCA Patient Maintain Cytoarchitecture despite Reduced levels of Mutant AIPL1
- (2020) Dunja Lukovic et al. Scientific Reports
- Organoids and Microphysiological Systems: New Tools for Ophthalmic Drug Discovery
- (2020) Jing Bai et al. Frontiers in Pharmacology
- A Method for Developing Novel 3D Cornea-on-a-Chip Using Primary Murine Corneal Epithelial and Endothelial Cells
- (2020) Jing Bai et al. Frontiers in Pharmacology
- Role of RB1 in human embryonic stem cell-derived retinal organoids
- (2020) Canbin Zheng et al. DEVELOPMENTAL BIOLOGY
- Precision metabolome reprogramming for imprecision therapeutics in retinitis pigmentosa
- (2020) Salvatore Caruso et al. JOURNAL OF CLINICAL INVESTIGATION
- Human organoids: model systems for human biology and medicine
- (2020) Jihoon Kim et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Human Organs-on-Chips for Virology
- (2020) Huaqi Tang et al. TRENDS IN MICROBIOLOGY
- Retinal Ganglion Cells With a Glaucoma OPTN(E50K) Mutation Exhibit Neurodegenerative Phenotypes when Derived from Three-Dimensional Retinal Organoids
- (2020) Kirstin B. VanderWall et al. Stem Cell Reports
- Modeling and Rescue of RP2 Retinitis Pigmentosa Using iPSC-Derived Retinal Organoids
- (2020) Amelia Lane et al. Stem Cell Reports
- Generation, transcriptome profiling, and functional validation of cone-rich human retinal organoids
- (2019) Sangbae Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5
- (2019) Peter M. Quinn et al. Stem Cell Reports
- A Cleared View on Retinal Organoids
- (2019) Virginia Cora et al. Cells
- Opacification of lentoid bodies derived from human induced pluripotent stem cells is accelerated by hydrogen peroxide and involves protein aggregation
- (2019) Zhenwei Qin et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Collective cell migration: general themes and new paradigms
- (2019) Caren Norden et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- A novel electro-chemotactic approach to impact the directional migration of transplantable retinal progenitor cells
- (2019) Shawn Mishra et al. EXPERIMENTAL EYE RESEARCH
- Multiscale reverse engineering of the human ocular surface
- (2019) Jeongyun Seo et al. NATURE MEDICINE
- Modeling Retinitis Pigmentosa: Retinal Organoids Generated From the iPSCs of a Patient With the USH2A Mutation Show Early Developmental Abnormalities
- (2019) Yonglong Guo et al. Frontiers in Cellular Neuroscience
- Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform
- (2019) Kevin Achberger et al. eLife
- Generation and Characterization of Induced Pluripotent Stem Cells and Retinal Organoids From a Leber’s Congenital Amaurosis Patient With Novel RPE65 Mutations
- (2019) Guilan Li et al. Frontiers in Molecular Neuroscience
- Dry Eye Disease: Emerging Approaches to Disease Analysis and Therapy
- (2019) Mostafa Heidari et al. Journal of Clinical Medicine
- Retinogenesis of the Human Fetal Retina: An Apical Polarity Perspective
- (2019) Peter M.J. Quinn et al. Genes
- Morphological and Molecular Defects in Human Three-Dimensional Retinal Organoid Model of X-Linked Juvenile Retinoschisis
- (2019) Kang-Chieh Huang et al. Stem Cell Reports
- Invertebrate Retinal Progenitors as Regenerative Models in a Microfluidic System
- (2019) Pena et al. Cells
- Comparative transcriptome analysis of hESC- and iPSC-derived lentoid bodies
- (2019) Muhammad Ali et al. Scientific Reports
- Light-focusing human micro-lenses generated from pluripotent stem cells model lens development and drug-induced cataract in vitro
- (2018) Patricia Murphy et al. DEVELOPMENT
- Assessment of AAV Vector Tropisms for Mouse and Human Pluripotent Stem Cell–Derived RPE and Photoreceptor Cells
- (2018) Anai Gonzalez-Cordero et al. HUMAN GENE THERAPY
- CRB2 in immature photoreceptors determines the superior-inferior symmetry of the developing retina to maintain retinal structure and function
- (2018) Peter M Quinn et al. HUMAN MOLECULAR GENETICS
- A compartmentalized microfluidic chip with crisscross microgrooves and electrophysiological electrodes for modeling the blood–retinal barrier
- (2018) Jose Yeste et al. LAB ON A CHIP
- A microengineered human corneal epithelium-on-a-chip for eye drops mass transport evaluation
- (2018) Devasier Bennet et al. LAB ON A CHIP
- Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells in Macular Degeneration
- (2018) Manjit S. Mehat et al. OPHTHALMOLOGY
- Clustered Regularly Interspaced Short Palindromic Repeats-Based Genome Surgery for the Treatment of Autosomal Dominant Retinitis Pigmentosa
- (2018) Yi-Ting Tsai et al. OPHTHALMOLOGY
- Establishment of Immunodeficient Retinal Degeneration Model Mice and Functional Maturation of Human ESC-Derived Retinal Sheets after Transplantation
- (2018) Satoshi Iraha et al. Stem Cell Reports
- Gene Correction Reverses Ciliopathy and Photoreceptor Loss in iPSC-Derived Retinal Organoids from Retinitis Pigmentosa Patients
- (2018) Wen-Li Deng et al. Stem Cell Reports
- Collective adhesion and displacement of retinal progenitor cells upon extracellular matrix substrates of transplantable biomaterials
- (2018) Ankush Thakur et al. Journal of Tissue Engineering
- Retinal Ganglion Cell replacement: current status and challenges ahead
- (2018) Adam M. Miltner et al. DEVELOPMENTAL DYNAMICS
- Loss of CRB2 in Müller glial cells modifies a CRB1-associated retinitis pigmentosa phenotype into a Leber congenital amaurosis phenotype
- (2018) Peter M Quinn et al. HUMAN MOLECULAR GENETICS
- Three-Dimensional Retinal Organoids Facilitate the Investigation of Retinal Ganglion Cell Development, Organization and Neurite Outgrowth from Human Pluripotent Stem Cells
- (2018) Clarisse M. Fligor et al. Scientific Reports
- A three-dimensional organoid model recapitulates tumorigenic aspects and drug responses of advanced human retinoblastoma
- (2018) Duangporn Saengwimol et al. Scientific Reports
- Characterization and Transplantation of CD73-Positive Photoreceptors Isolated from Human iPSC-Derived Retinal Organoids
- (2018) Giuliana Gagliardi et al. Stem Cell Reports
- Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines
- (2018) Elizabeth E. Capowski et al. DEVELOPMENT
- Thyroid hormone signaling specifies cone subtypes in human retinal organoids
- (2018) Kiara C. Eldred et al. SCIENCE
- Deconstructing Retinal Organoids: Single Cell RNA-Seq Reveals the Cellular Components of Human Pluripotent Stem Cell-Derived Retina
- (2018) Joseph Collin et al. STEM CELLS
- Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa
- (2018) Adriana Buskin et al. Nature Communications
- Generation of orthotopically functional salivary gland from embryonic stem cells
- (2018) Junichi Tanaka et al. Nature Communications
- Corneal cell therapy: with iPSCs, it is no more a far-sight
- (2018) Koushik Chakrabarty et al. Stem Cell Research & Therapy
- Revolution in Gene Medicine Therapy and Genome Surgery
- (2018) David J. Jiang et al. Genes
- Medium- to long-term survival and functional examination of human iPSC-derived retinas in rat and primate models of retinal degeneration
- (2018) Hung-Ya Tu et al. EBioMedicine
- Temporal expression of CD184(CXCR4) and CD171(L1CAM) identifies distinct early developmental stages of human retinal ganglion cells in embryonic stem cell derived retina
- (2017) J.G. Aparicio et al. EXPERIMENTAL EYE RESEARCH
- The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis
- (2017) Issam Aldiri et al. NEURON
- Genotypic and Phenotypic Characteristics of CRB1 -Associated Retinal Dystrophies
- (2017) Mays Talib et al. OPHTHALMOLOGY
- Scaling and maintenance of corneal thickness during aging
- (2017) Takenori Inomata et al. PLoS One
- Chemically-induced photoreceptor degeneration and protection in mouse iPSC-derived three-dimensional retinal organoids
- (2017) Shin-ichiro Ito et al. Stem Cell Research
- Generation of Storable Retinal Organoids and Retinal Pigmented Epithelium from Adherent Human iPS Cells in Xeno-Free and Feeder-Free Conditions
- (2017) Sacha Reichman et al. STEM CELLS
- An In Vitro Model for the Ocular Surface and Tear Film System
- (2017) Qiaozhi Lu et al. Scientific Reports
- An Eye Organoid Approach Identifies Six3 Suppression of R-spondin 2 as a Critical Step in Mouse Neuroretina Differentiation
- (2017) Nozomu Takata et al. Cell Reports
- In Vitro Modeling Using Ciliopathy-Patient-Derived Cells Reveals Distinct Cilia Dysfunctions Caused by CEP290 Mutations
- (2017) Hiroko Shimada et al. Cell Reports
- The CRB1 Complex: Following the Trail of Crumbs to a Feasible Gene Therapy Strategy
- (2017) Peter M. Quinn et al. Frontiers in Neuroscience
- A New Long Noncoding RNA ALB Regulates Autophagy by Enhancing the Transformation of LC3BI to LC3BII during Human Lens Development
- (2017) Qiuli Fu et al. Molecular Therapy-Nucleic Acids
- Differentiation and Transplantation of Embryonic Stem Cell-Derived Cone Photoreceptors into a Mouse Model of End-Stage Retinal Degeneration
- (2017) Kamil Kruczek et al. Stem Cell Reports
- Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors
- (2017) Anai Gonzalez-Cordero et al. Stem Cell Reports
- Human Lacrimal Gland Gene Expression
- (2017) Vinay Kumar Aakalu et al. PLoS One
- Cornea organoids from human induced pluripotent stem cells
- (2017) James W. Foster et al. Scientific Reports
- Photoreceptor Outer Segment-like Structures in Long-Term 3D Retinas from Human Pluripotent Stem Cells
- (2017) Karl J. Wahlin et al. Scientific Reports
- Ageing and ocular surface immunity
- (2016) Alireza Mashaghi et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Modeling Development and Disease with Organoids
- (2016) Hans Clevers CELL
- Identification and Correction of Mechanisms Underlying Inherited Blindness in Human iPSC-Derived Optic Cups
- (2016) David A. Parfitt et al. Cell Stem Cell
- Pluripotent Stem Cells and Other Innovative Strategies for the Treatment of Ocular Surface Diseases
- (2016) Johanna Erbani et al. Stem Cell Reviews and Reports
- Three-Dimensional Culture of Functional Adult Rabbit Lacrimal Gland Epithelial Cells on Decellularized Scaffold
- (2016) Hui Lin et al. TISSUE ENGINEERING PART A
- Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors
- (2016) R. A. Pearson et al. Nature Communications
- Retinal transplantation of photoreceptors results in donor–host cytoplasmic exchange
- (2016) Tiago Santos-Ferreira et al. Nature Communications
- Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion
- (2016) Mandeep S. Singh et al. Nature Communications
- The Ciliary Margin Zone of the Mammalian Retina Generates Retinal Ganglion Cells
- (2016) Florencia Marcucci et al. Cell Reports
- Lacrimal Gland Repair Using Progenitor Cells
- (2016) Anastasia Gromova et al. Stem Cells Translational Medicine
- Pluripotent Stem Cells and Other Innovative Strategies for the Treatment of Ocular Surface Diseases
- (2016) Johanna Erbani et al. Stem Cell Reviews and Reports
- Intercellular Adhesion-Dependent Cell Survival and ROCK-Regulated Actomyosin-Driven Forces Mediate Self-Formation of a Retinal Organoid
- (2016) Albert Lowe et al. Stem Cell Reports
- A model microfluidics-based system for the human and mouse retina
- (2015) Shawn Mishra et al. BIOMEDICAL MICRODEVICES
- Gene therapy into photoreceptors and Müller glial cells restores retinal structure and function in CRB1 retinitis pigmentosa mouse models
- (2015) Lucie P. Pellissier et al. HUMAN MOLECULAR GENETICS
- Contribution of Microglia-Mediated Neuroinflammation to Retinal Degenerative Diseases
- (2015) Maria H. Madeira et al. MEDIATORS OF INFLAMMATION
- Transcriptome Dynamics of Developing Photoreceptors in Three-Dimensional Retina Cultures Recapitulates Temporal Sequence of Human Cone and Rod Differentiation Revealing Cell Surface Markers and Gene Networks
- (2015) Rossukon Kaewkhaw et al. STEM CELLS
- Engineering of a Secretory Active Three-Dimensional Lacrimal Gland Construct on the Basis of Decellularized Lacrimal Gland Tissue
- (2015) Kristina Spaniol et al. TISSUE ENGINEERING PART A
- Generation of a ciliary margin-like stem cell niche from self-organizing human retinal tissue
- (2015) Atsushi Kuwahara et al. Nature Communications
- In vitro generation of human pluripotent stem cell derived lung organoids
- (2015) Briana R Dye et al. eLife
- Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation
- (2014) Elizabeth E. Capowski et al. HUMAN MOLECULAR GENETICS
- Correction: AAV9 Targets Cone Photoreceptors in the Nonhuman Primate Retina
- (2014) Luk H. Vandenberghe et al. PLoS One
- Comparison of the transcriptional landscapes between human and mouse tissues
- (2014) Shin Lin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The CRB1 and adherens junction complex proteins in retinal development and maintenance
- (2014) Celso Henrique Alves et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Organogenesis in a dish: Modeling development and disease using organoid technologies
- (2014) M. A. Lancaster et al. SCIENCE
- Daylight Vision Repair by Cell Transplantation
- (2014) Tiago Santos-Ferreira et al. STEM CELLS
- Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs
- (2014) Xiufeng Zhong et al. Nature Communications
- Three hundred and sixty degree retinotomy for retinal detachments with severe proliferative vitreoretinopathy
- (2013) Steven Garnier et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Unknown
- (2013) Yao Li et al. MOLECULAR MEDICINE
- Functional lacrimal gland regeneration by transplantation of a bioengineered organ germ
- (2013) Masatoshi Hirayama et al. Nature Communications
- Functional salivary gland regeneration by transplantation of a bioengineered organ germ
- (2013) Miho Ogawa et al. Nature Communications
- Self-Formation of Optic Cups and Storable Stratified Neural Retina from Human ESCs
- (2012) Tokushige Nakano et al. Cell Stem Cell
- The Human Rhodopsin Kinase Promoter in an AAV5 Vector Confers Rod- and Cone-Specific Expression in the Primate Retina
- (2012) Shannon E. Boye et al. HUMAN GENE THERAPY
- Generation of functional thyroid from embryonic stem cells
- (2012) Francesco Antonica et al. NATURE
- Restoration of vision after transplantation of photoreceptors
- (2012) R. A. Pearson et al. NATURE
- Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches
- (2012) Koh-ei Toyoshima et al. Nature Communications
- CRB1mutations in inherited retinal dystrophies
- (2011) Kinga Bujakowska et al. HUMAN MUTATION
- Self-organizing optic-cup morphogenesis in three-dimensional culture
- (2011) Mototsugu Eiraku et al. NATURE
- Mouse embryonic stem cell culture for generation of three-dimensional retinal and cortical tissues
- (2011) Mototsugu Eiraku et al. Nature Protocols
- Functional Tooth Regeneration Using a Bioengineered Tooth Unit as a Mature Organ Replacement Regenerative Therapy
- (2011) Masamitsu Oshima et al. PLoS One
- Chloroquine treatment of ARPE-19 cells leads to lysosome dilation and intracellular lipid accumulation: possible implications of lysosomal dysfunction in macular degeneration
- (2011) Patrick M Chen et al. Cell and Bioscience
- Blood-Retinal Barrier
- (2010) José Cunha-Vaz et al. EUROPEAN JOURNAL OF OPHTHALMOLOGY
- Efficient generation of lens progenitor cells and lentoid bodies from human embryonic stem cells in chemically defined conditions
- (2010) Chunbo Yang et al. FASEB JOURNAL
- A Review of Three-Dimensional In Vitro Tissue Models for Drug Discovery and Transport Studies
- (2010) Nelita T. Elliott et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro
- (2010) Jason R. Spence et al. NATURE
- Transplantation of Reprogrammed Embryonic Stem Cells Improves Visual Function in a Mouse Model for Retinitis Pigmentosa
- (2010) Nan-Kai Wang et al. TRANSPLANTATION
- Cultivation of lacrimal gland acinar cells in a microgravity environment
- (2009) S Schrader et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Integration and application of vitrified collagen in multilayered microfluidic devices for corneal microtissue culture
- (2009) Christopher M. Puleo et al. LAB ON A CHIP
- Spemann’s organizer and the self-regulation of embryonic fields
- (2009) E.M. De Robertis MECHANISMS OF DEVELOPMENT
- Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
- (2009) Toshiro Sato et al. NATURE
- Fully functional bioengineered tooth replacement as an organ replacement therapy
- (2009) E. Ikeda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modeling early retinal development with human embryonic and induced pluripotent stem cells
- (2009) J. S. Meyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals
- (2008) Mototsugu Eiraku et al. Cell Stem Cell
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