RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences

Impact of the Protein Data Bank on antineoplastic approvals

(2020) John D. Westbrook et al.   DRUG DISCOVERY TODAY

Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2

(2020) Renhong Yan et al.   SCIENCE

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

(2020) David E. Gordon et al.   NATURE

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors

(2020) Zhenming Jin et al.   NATURE

Crystal structure of Nsp15 endoribonuclease NendoU from SARS‐CoV ‐2

(2020) Youngchang Kim et al.   PROTEIN SCIENCE

Structure of the RNA-dependent RNA polymerase from COVID-19 virus

(2020) Yan Gao et al.   SCIENCE

A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV

(2020) Meng Yuan et al.   SCIENCE

Insights from 20 years of the Molecule of the Month

(2020) David S. Goodsell et al.   BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION

3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice

(2020) Athri D. Rathnayake et al.   Science Translational Medicine

Integrative illustration for coronavirus outreach

(2020) David S. Goodsell et al.   PLOS BIOLOGY

Real time structural search of the Protein Data Bank

(2020) Dmytro Guzenko et al.   PLoS Computational Biology

The GTEx Consortium atlas of genetic regulatory effects across human tissues

(2020)   SCIENCE

BinaryCIF and CIFTools—Lightweight, efficient and extensible macromolecular data management

(2020) David Sehnal et al.   PLoS Computational Biology

CellPAINT: Interactive Illustration of Dynamic Mesoscale Cellular Environments

(2019) Adam Gardner et al.   IEEE COMPUTER GRAPHICS AND APPLICATIONS

Delicate structural coordination of the Severe Acute Respiratory Syndrome coronavirus Nsp13 upon ATP hydrolysis

(2019) Zhihui Jia et al.   NUCLEIC ACIDS RESEARCH

RCSB Protein Data Bank: Enabling biomedical research and drug discovery

(2019) David S. Goodsell et al.   PROTEIN SCIENCE

Worldwide Protein Data Bank biocuration supporting open access to high-quality 3D structural biology data

(2018) Jasmine Y Young et al.   Database-The Journal of Biological Databases and Curation

Protein Data Bank: the single global archive for 3D macromolecular structure data

(2018) et al.   NUCLEIC ACIDS RESEARCH

UniProt: a worldwide hub of protein knowledge

(2018)   NUCLEIC ACIDS RESEARCH

RCSB Protein Data Bank: biological macromolecular structures enabling research and education in fundamental biology, biomedicine, biotechnology and energy

(2018) Stephen K Burley et al.   NUCLEIC ACIDS RESEARCH

The Gene Ontology Resource: 20 years and still GOing strong

(2018)   NUCLEIC ACIDS RESEARCH

How Structural Biologists and the Protein Data Bank Contributed to Recent FDA New Drug Approvals

(2018) John D. Westbrook et al.   STRUCTURE

Analysis of impact metrics for the Protein Data Bank

(2018) Christopher Markosian et al.   Scientific Data

Data management: A global coalition to sustain core data

(2017) Warwick P. Anderson   NATURE

MMseqs2 enables sensitive protein sequence searching for the analysis of massive data sets

(2017) Martin Steinegger et al.   NATURE BIOTECHNOLOGY

PDBe: towards reusable data delivery infrastructure at protein data bank in Europe

(2017) Saqib Mir et al.   NUCLEIC ACIDS RESEARCH

DrugBank 5.0: a major update to the DrugBank database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

New tools and functions in data-out activities at Protein Data Bank Japan (PDBj)

(2017) Akira R. Kinjo et al.   PROTEIN SCIENCE

OneDep: Unified wwPDB System for Deposition, Biocuration, and Validation of Macromolecular Structures in the PDB Archive

(2017) Jasmine Y. Young et al.   STRUCTURE

Validation of Structures in the Protein Data Bank

(2017) Swanand Gore et al.   STRUCTURE

Pharos: Collating protein information to shed light on the druggable genome

(2016) Dac-Trung Nguyen et al.   NUCLEIC ACIDS RESEARCH

CATH: an expanded resource to predict protein function through structure and sequence

(2016) Natalie L. Dawson et al.   NUCLEIC ACIDS RESEARCH

Structure of faustovirus, a large dsDNA virus

(2016) Thomas Klose et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The FAIR Guiding Principles for scientific data management and stewardship

(2016) Mark D. Wilkinson et al.   Scientific Data

Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation

(2015) Nuala A. O'Leary et al.   NUCLEIC ACIDS RESEARCH

The Pfam protein families database: towards a more sustainable future

(2015) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

The RCSB PDB “Molecule of the Month”: Inspiring a Molecular View of Biology

(2015) David S. Goodsell et al.   PLOS BIOLOGY

The chemical component dictionary: complete descriptions of constituent molecules in experimentally determined 3D macromolecules in the Protein Data Bank

(2014) John D. Westbrook et al.   BIOINFORMATICS

The RCSB Protein Data Bank: views of structural biology for basic and applied research and education

(2014) Peter W. Rose et al.   NUCLEIC ACIDS RESEARCH

Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics

(2013) Gongpu Zhao et al.   NATURE

SCOP2 prototype: a new approach to protein structure mining

(2013) Antonina Andreeva et al.   NUCLEIC ACIDS RESEARCH

SCOPe: Structural Classification of Proteins—extended, integrating SCOP and ASTRAL data and classification of new structures

(2013) Naomi K. Fox et al.   NUCLEIC ACIDS RESEARCH

The RCSB Protein Data Bank: new resources for research and education

(2012) Peter W. Rose et al.   NUCLEIC ACIDS RESEARCH

A conditional knockout resource for the genome-wide study of mouse gene function

(2011) William C. Skarnes et al.   NATURE

The RCSB Protein Data Bank: redesigned web site and web services

(2010) P. W. Rose et al.   NUCLEIC ACIDS RESEARCH

BioMagResBank (BMRB) as a partner in the Worldwide Protein Data Bank (wwPDB): new policies affecting biomolecular NMR depositions

(2008) John L. Markley et al.   JOURNAL OF BIOMOLECULAR NMR