Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation

Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer

(2020) Nuno Apóstolo et al.   Nature Communications

Hippocampal mossy fibers synapses in CA3 pyramidal cells are altered at an early stage in a mouse model of Alzheimer's disease

(2019) Silvia Viana da Silva et al.   JOURNAL OF NEUROSCIENCE

Elevated synaptic vesicle release probability in synaptophysin/gyrin family quadruple knockouts

(2019) Mathan K Raja et al.   eLife

Intersection of pathological tau and microglia at the synapse

(2019) Thomas Vogels et al.   Acta Neuropathologica Communications

Astroglial contribution to tau-dependent neurodegeneration

(2019) Marta Sidoryk-Węgrzynowicz et al.   BIOCHEMICAL JOURNAL

Tau-mediated synaptic and neuronal dysfunction in neurodegenerative disease

(2018) Tara E Tracy et al.   CURRENT OPINION IN NEUROBIOLOGY

Tau filaments in neurodegenerative diseases

(2018) Michel Goedert   FEBS LETTERS

Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2)

(2018) Li Zhong et al.   Molecular Neurodegeneration

Synaptogyrin-3 Mediates Presynaptic Dysfunction Induced by Tau

(2018) Joseph McInnes et al.   NEURON

Tau and neuroinflammation: What impact for Alzheimer's Disease and Tauopathies?

(2018) Cyril Laurent et al.   Biomedical Journal

Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies

(2018) Borislav Dejanovic et al.   NEURON

Glial contributions to neurodegeneration in tauopathies

(2017) Cheryl E. G. Leyns et al.   Molecular Neurodegeneration

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

(2017) Yang Shi et al.   NATURE

Tau association with synaptic vesicles causes presynaptic dysfunction

(2017) Lujia Zhou et al.   Nature Communications

Altered Synapse Stability in the Early Stages of Tauopathy

(2017) Johanna S. Jackson et al.   Cell Reports

Tau Oligomers Associate with Inflammation in the Brain and Retina of Tauopathy Mice and in Neurodegenerative Diseases

(2016) Ashley N. Nilson et al.   JOURNAL OF ALZHEIMERS DISEASE

Co-immunoprecipitation with Tau Isoform-specific Antibodies Reveals Distinct Protein Interactions and Highlights a Putative Role for 2N Tau in Disease

(2016) Chang Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice

(2016) Jonathan Gilley et al.   NEUROBIOLOGY OF AGING

Tau in physiology and pathology

(2015) Yipeng Wang et al.   NATURE REVIEWS NEUROSCIENCE

The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

(2014) Tara L. Spires-Jones et al.   NEURON

Fractalkine activates NRF2/NFE2L2 and heme oxygenase 1 to restrain tauopathy-induced microgliosis

(2013) Isabel Lastres-Becker et al.   BRAIN

Presence of Reactive Microglia and Neuroinflammatory Mediators in a Case of Frontotemporal Dementia with P301S Mutation

(2011) Arianna Bellucci et al.   Neurodegenerative Diseases

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Synapse loss in dementias

(2010) Ryan Clare et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

(2010) Brian R. Hoover et al.   NEURON