Endoplasmic reticulum stress and oxidative stress contribute to neuronal pyroptosis caused by cerebral venous sinus thrombosis in rats: Involvement of TXNIP/peroxynitrite-NLRP3 inflammasome activation

Valproic acid attenuates global cerebral ischemia/reperfusion injury in gerbils via anti-pyroptosis pathways

(2019) Shu Zhu et al.   NEUROCHEMISTRY INTERNATIONAL

Caspase-1 inhibitor exerts brain-protective effects against sepsis-associated encephalopathy and cognitive impairments in a mouse model of sepsis

(2019) Xi-e Xu et al.   BRAIN BEHAVIOR AND IMMUNITY

Cilostazol ameliorates ischemia/reperfusion-induced tight junction disruption in brain endothelial cells by inhibiting endoplasmic reticulum stress

(2019) Ding Nan et al.   FASEB JOURNAL

NLRP3 inflammasome as a potential treatment in ischemic stroke concomitant with diabetes

(2019) Pu Hong et al.   Journal of Neuroinflammation

Cerebral Venous Thrombosis: an Update

(2019) José M. Ferro et al.   Current Neurology and Neuroscience Reports

Endoplasmic reticulum stress may activate NLRP3 inflammasomes via TXNIP in preeclampsia

(2019) Yong Yang et al.   CELL AND TISSUE RESEARCH

EPO and TMBIM3/GRINA Promote the Activation of the Adaptive Arm and Counteract the Terminal Arm of the Unfolded Protein Response after Murine Transient Cerebral Ischemia

(2019) Pardes Habib et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Txnip mediates glucocorticoid-activated NLRP3 inflammatory signaling in mouse microglia

(2019) Veni Bharti et al.   NEUROCHEMISTRY INTERNATIONAL

Pyroptosis is a critical inflammatory pathway in the placenta from early onset preeclampsia and in human trophoblasts exposed to hypoxia and endoplasmic reticulum stressors

(2019) Shi-Bin Cheng et al.   Cell Death & Disease

Early BBB breakdown and subacute inflammasome activation and pyroptosis as a result of cerebral venous thrombosis

(2018) Sherif Rashad et al.   BRAIN RESEARCH

IRE1α inhibition decreased TXNIP/NLRP3 inflammasome activation through miR-17-5p after neonatal hypoxic–ischemic brain injury in rats

(2018) Di Chen et al.   Journal of Neuroinflammation

Ketamine induces hippocampal apoptosis through a mechanism associated with the caspase-1 dependent pyroptosis

(2018) Zhi Ye et al.   NEUROPHARMACOLOGY

Mitochondrial dysfunction induces NLRP3 inflammasome activation during cerebral ischemia/reperfusion injury

(2018) Zhe Gong et al.   Journal of Neuroinflammation

Thioredoxin-interacting protein links endoplasmic reticulum stress to inflammatory brain injury and apoptosis after subarachnoid haemorrhage

(2017) Qing Zhao et al.   Journal of Neuroinflammation

Peroxynitrite Activates the NLRP3 Inflammasome Cascade in SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis

(2017) Ilaria Bellezza et al.   MOLECULAR NEUROBIOLOGY

Cerebral venous thrombosis

(2017) Suzanne M. Silvis et al.   Nature Reviews Neurology

Time courses of post-injury mitochondrial oxidative damage and respiratory dysfunction and neuronal cytoskeletal degradation in a rat model of focal traumatic brain injury

(2017) Rachel L. Hill et al.   NEUROCHEMISTRY INTERNATIONAL

Oxidative stress and glutamate excitotoxicity contribute to apoptosis in cerebral venous sinus thrombosis

(2016) Hari Shanker Tiwari et al.   NEUROCHEMISTRY INTERNATIONAL

Reactive Oxygen Species-Induced TXNIP Drives Fructose-Mediated Hepatic Inflammation and Lipid Accumulation Through NLRP3 Inflammasome Activation

(2015) Xian Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

P2X7R blockade prevents NLRP3 inflammasome activation and brain injury in a rat model of intracerebral hemorrhage: involvement of peroxynitrite

(2015) Liang Feng et al.   Journal of Neuroinflammation

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Peroxynitrite decomposition catalyst prevents matrix metalloproteinase-9 activation and neurovascular injury after hemoglobin injection into the caudate nucleus of rats

(2015) R. Ding et al.   NEUROSCIENCE

Photothrombosis combined with thrombin injection establishes a rat model of cerebral venous sinus thrombosis

(2015) C. Chen et al.   NEUROSCIENCE

A study of ER stress in rat model of cerebral venous sinus thrombosis

(2015) Hari Shanker Tiwari et al.   NEUROSCIENCE LETTERS

Curcumin attenuates glutamate neurotoxicity in the hippocampus by suppression of ER stress-associated TXNIP/NLRP3 inflammasome activation in a manner dependent on AMPK

(2015) Ying Li et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Blood–brain barrier disruption induced by hemoglobin in vivo: Involvement of up-regulation of nitric oxide synthase and peroxynitrite formation

(2014) Rui Ding et al.   BRAIN RESEARCH

Thioredoxin-Interacting Protein: a Novel Target for Neuroprotection in Experimental Thromboembolic Stroke in Mice

(2014) Tauheed Ishrat et al.   MOLECULAR NEUROBIOLOGY

Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome

(2012) Christine M. Oslowski et al.   Cell Metabolism

IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

(2012) Alana G. Lerner et al.   Cell Metabolism

Induction of thioredoxin-interacting protein is mediated by oxidative stress, calcium, and glucose after brain injury in mice

(2012) Gab Seok Kim et al.   NEUROBIOLOGY OF DISEASE

Establishing a new rat model of central venous sinus thrombosis and analyzing its pathophysiological and apoptotic changes

(2011) Hui Yang et al.   JOURNAL OF NEUROSCIENCE METHODS

Neurovascular Protective Effect of FeTPPs in N-Methyl-D-Aspartate Model

(2010) Mohammed M.H. Al-Gayyar et al.   AMERICAN JOURNAL OF PATHOLOGY

NLRP3 has a sweet tooth

(2010) Beckley K Davis et al.   NATURE IMMUNOLOGY

Cerebral Venous Sinus Thrombosis Risk Factors

(2009) Mohammad Saadatnia et al.   International Journal of Stroke

Development of a new model of transvenous thrombosis in the pig superior sagittal sinus using thrombin injection and balloon occlusion

(2009) J. Wang et al.   JOURNAL OF NEURORADIOLOGY

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

Studies of free radical generation by neurons in a rat model of cerebral venous sinus thrombosis

(2008) Amit Kumar Srivastava et al.   NEUROSCIENCE LETTERS