Thioredoxin-Interacting Protein: a Novel Target for Neuroprotection in Experimental Thromboembolic Stroke in Mice

Neuroprotective Properties and Mechanisms of Resveratrol in in Vitro and in Vivo Experimental Cerebral Stroke Models

(2013) Nilendra Singh et al.   ACS Chemical Neuroscience

Thioredoxin-Interacting Protein Expression Is Required for VEGF-Mediated Angiogenic Signal in Endothelial Cells

(2013) Mohammed A. Abdelsaid et al.   ANTIOXIDANTS & REDOX SIGNALING

Deletion of thioredoxin-interacting protein preserves retinal neuronal function by preventing inflammation and vascular injury

(2013) M F El-Azab et al.   BRITISH JOURNAL OF PHARMACOLOGY

AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC

(2013) V Sagulenko et al.   CELL DEATH AND DIFFERENTIATION

Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet

(2013) Islam N. Mohamed et al.   DIABETOLOGIA

Candesartan Reduces the Hemorrhage Associated with Delayed Tissue Plasminogen Activator Treatment in Rat Embolic Stroke

(2013) Tauheed Ishrat et al.   NEUROCHEMICAL RESEARCH

TXNIP Deficiency Exacerbates Endotoxic Shock via the Induction of Excessive Nitric Oxide Synthesis

(2013) Young-Jun Park et al.   PLoS Pathogens

Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome

(2012) Christine M. Oslowski et al.   Cell Metabolism

Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction

(2012) Kate Schroder et al.   IMMUNOBIOLOGY

Induction of thioredoxin-interacting protein is mediated by oxidative stress, calcium, and glucose after brain injury in mice

(2012) Gab Seok Kim et al.   NEUROBIOLOGY OF DISEASE

Remote Ischemic Perconditioning Is Effective Alone and in Combination With Intravenous Tissue-Type Plasminogen Activator in Murine Model of Embolic Stroke

(2012) Md Nasrul Hoda et al.   STROKE

NLRP3-Inflammasome Activating DAMPs Stimulate an Inflammatory Response in Glia in the Absence of Priming Which Contributes to Brain Inflammation after Injury

(2012) Catherine Diane Savage et al.   Frontiers in Immunology

Amino-Functionalized Polystyrene Nanoparticles Activate the NLRP3 Inflammasome in Human Macrophages

(2011) Oleg Lunov et al.   ACS Nano

Thioredoxin interacting protein is a novel mediator of retinal inflammation and neurotoxicity

(2011) Mohammed MH Al-Gayyar et al.   BRITISH JOURNAL OF PHARMACOLOGY

Heart Disease and Stroke Statistics—2012 Update

(2011) et al.   CIRCULATION

Caspase-1 Promiscuity Is Counterbalanced by Rapid Inactivation of Processed Enzyme

(2011) John G. Walsh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quercetin Protects Against Oxidative Stress Associated Damages in a Rat Model of Transient Focal Cerebral Ischemia and Reperfusion

(2011) Ajmal Ahmad et al.   NEUROCHEMICAL RESEARCH

The Emerging Role of the Thioredoxin System in Angiogenesis

(2010) Louise L. Dunn et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Thioredoxin and glutaredoxin system proteins—immunolocalization in the rat central nervous system

(2010) Maria Laura Aon-Bertolino et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

trans-Resveratrol downregulates Txnip overexpression occurring during liver ischemia-reperfusion

(2010) Valérie Nivet-Antoine et al.   BIOCHIMIE

Resveratrol attenuates 6-hydroxydopamine-induced oxidative damage and dopamine depletion in rat model of Parkinson's disease

(2010) Mohd.Moshahid Khan et al.   BRAIN RESEARCH

Inflammasomes: current understanding and open questions

(2010) Franz Bauernfeind et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Therapeutic effects of resveratrol during acute periods following experimental ischemic stroke

(2010) Jin A. Shin et al.   JOURNAL OF NEUROIMMUNOLOGY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

The NLRP3 Inflammasome: A Sensor for Metabolic Danger?

(2010) K. Schroder et al.   SCIENCE

Inhibition of TXNIP expression in vivo blocks early pathologies of diabetic retinopathy

(2010) L Perrone et al.   Cell Death & Disease

Diabetes induces and calcium channel blockers prevent cardiac expression of proapoptotic thioredoxin-interacting protein

(2009) Junqin Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions

(2009) Lorena Perrone et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cutting Edge: TNF-  Mediates Sensitization to ATP and Silica via the NLRP3 Inflammasome in the Absence of Microbial Stimulation

(2009) L. Franchi et al.   JOURNAL OF IMMUNOLOGY

Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway

(2008) C.-L. Chen et al.   BLOOD

Resveratrol exerts its neuroprotective effect by modulating mitochondrial dysfunctions and associated cell death during cerebral ischemia

(2008) Seema Yousuf et al.   BRAIN RESEARCH

Diabetes impairs exercise training-associated thioredoxin response and glutathione status in rat brain

(2008) Zekine Lappalainen et al.   JOURNAL OF APPLIED PHYSIOLOGY

Inhibition of the Inflammasome Complex Reduces the Inflammatory Response after Thromboembolic Stroke in Mice

(2008) Denise P Abulafia et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Txnip balances metabolic and growth signaling via PTEN disulfide reduction

(2008) S. T. Y. Hui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative Stress and Matrix Metalloproteinase-9 in Acute Ischemic Stroke

(2007) Peter J. Kelly et al.   STROKE