Mitochondrial dysfunction induces NLRP3 inflammasome activation during cerebral ischemia/reperfusion injury

Ketamine induces hippocampal apoptosis through a mechanism associated with the caspase-1 dependent pyroptosis

(2018) Zhi Ye et al.   NEUROPHARMACOLOGY

2-Cl-MGV-1 Ameliorates Apoptosis in the Thalamus and Hippocampus and Cognitive Deficits After Cortical Infarct in Rats

(2017) Yicong Chen et al.   STROKE

Mitochondria and the NLRP3 inflammasome: physiological and pathological relevance

(2016) Je-Wook Yu et al.   ARCHIVES OF PHARMACAL RESEARCH

NLRP3 Is Involved in Ischemia/Reperfusion Injury

(2016) Zhiliang Guo et al.   CNS & Neurological Disorders-Drug Targets

NLRP3 inflammasome: a promising target in ischemic stroke

(2016) Li Gao et al.   INFLAMMATION RESEARCH

Initial research on the relationship between let-7 family members in the serum and massive cerebral infarction

(2016) Zhe Gong et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Activating Autophagy in Hippocampal Cells Alleviates the Morphine-Induced Memory Impairment

(2016) Jingrui Pan et al.   MOLECULAR NEUROBIOLOGY

Diazoxide protects L6 skeletal myoblasts from H2O2-induced apoptosis via the phosphatidylinositol-3 kinase/Akt pathway

(2015) Wei Chen et al.   INFLAMMATION RESEARCH

Anti-apoptotic, anti-oxidant, and anti-inflammatory effects of thalidomide on cerebral ischemia/reperfusion injury in rats

(2015) Guadalupe Palencia et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Characteristic Changes of Astrocyte and Microglia in Rat Striatum Induced by 3-NP and MCAO

(2015) Shuhua Mu et al.   NEUROCHEMICAL RESEARCH

Upregulation of NLRP3 Inflammasome in the Tears and Ocular Surface of Dry Eye Patients

(2015) Liangliang Niu et al.   PLoS One

Mitochondria: diversity in the regulation of the NLRP3 inflammasome

(2015) Prajwal Gurung et al.   TRENDS IN MOLECULAR MEDICINE

NLRP3 Inflammasome Is Expressed and Functional in Mouse Brain Microglia but Not in Astrocytes

(2015) Audrey Gustin et al.   PLoS One

Inflammasome activation in response to dead cells and their metabolites

(2014) Hajime Kono et al.   CURRENT OPINION IN IMMUNOLOGY

Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye

(2014) Qinxiang Zheng et al.   EXPERIMENTAL EYE RESEARCH

NLRP3 Deficiency Ameliorates Neurovascular Damage in Experimental Ischemic Stroke

(2014) Fan Yang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mulberroside a protects against ischemic impairment in primary culture of rat cortical neurons after oxygen-glucose deprivation followed by reperfusion

(2014) Cai-Ping Wang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Sevoflurane postconditioning against cerebral ischemic neuronal injury is abolished in diet-induced obesity: Role of brain mitochondrial KATP channels

(2014) ZECHENG YANG et al.   Molecular Medicine Reports

Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke

(2013) D Yang-Wei Fann et al.   Cell Death & Disease

Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

(2012) Kenichi Shimada et al.   IMMUNITY

Redox control of NLRP3 inflammasome activation in health and disease

(2012) Anna Rubartelli   JOURNAL OF LEUKOCYTE BIOLOGY

NLRP3-Inflammasome Activating DAMPs Stimulate an Inflammatory Response in Glia in the Absence of Priming Which Contributes to Brain Inflammation after Injury

(2012) Catherine Diane Savage et al.   Frontiers in Immunology

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Manipulation of Host Cell Death Pathways during Microbial Infections

(2010) Mohamed Lamkanfi et al.   Cell Host & Microbe

The inflammasomes: mechanisms of activation and function

(2010) Eicke Latz   CURRENT OPINION IN IMMUNOLOGY

Critical functions of priming and lysosomal damage for NLRP3 activation

(2010) Veit Hornung et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Hypoxic tissues are associated with microvessel density following brain ischemia–reperfusion

(2010) Jin-rui Pan et al.   NEUROLOGICAL SCIENCES

Inhibition of the Inflammasome Complex Reduces the Inflammatory Response after Thromboembolic Stroke in Mice

(2008) Denise P Abulafia et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE