Recent Strategies and Applications for l-Asparaginase Confinement

Immobilization of L-Asparaginase on Magnetic Nanoparticles for Cancer Treatment

(2020) Hande Orhan et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

A comprehensive review on microbial l ‐asparaginase: Bioprocessing, characterization, and industrial applications

(2020) Subhash Chand et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Critical overview of the main features and techniques used for the evaluation of the clinical applicability of L-asparaginase as a biopharmaceutical to treat blood cancer

(2020) T.A. Costa-Silva et al.   BLOOD REVIEWS

Asparagine Synthetase in Cancer: Beyond Acute Lymphoblastic Leukemia

(2020) Martina Chiu et al.   Frontiers in Oncology

Enzyme co-immobilization: Always the biocatalyst designers' choice…or not?

(2020) Sara Arana-Peña et al.   BIOTECHNOLOGY ADVANCES

Insertion of carbon nanotubes in Langmuir-Blodgett films of stearic acid and asparaginase enhancing the catalytic performance

(2020) Luiz Henrique Rodrigues Rola Possarle et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Anticancer activity of gelatin-asparaginase nanobiocomposite against cervical and brain cancer cell lines

(2020) G. Baskar et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Immobilization of Naringinase from Aspergillus Niger on a Magnetic Polysaccharide Carrier

(2020) Joanna Bodakowska-Boczniewicz et al.   MOLECULES

Immobilization in Ionogel: A New Way to Improve the Activity and Stability of Candida antarctica Lipase B

(2020) Alfonso Escudero et al.   MOLECULES

Immobilization of Low-Cost Alternative Vegetable Peroxidase (Raphanus sativus L. peroxidase): Choice of Support/Technique and Characterization

(2020) Gabrielle Souza da Silva Barbosa et al.   MOLECULES

Overview of Carbon Nanotubes for Biomedical Applications

(2019) Juliette Simon et al.   Materials

Poly (lactic-co-glycolic acid) nanospheres allow for high l-asparaginase encapsulation yield and activity

(2019) Anna Emmanuela Medeiros de Brito et al.   Materials Science & Engineering C-Materials for Biological Applications

Acrylamide levels and dietary exposure from foods in the United States, an update based on 2011-2015 data

(2019) Eileen Abt et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Glutaminase activity of L-asparaginase contributes to durable preclinical activity against acute lymphoblastic leukemia

(2019) Wai Kin Chan et al.   MOLECULAR CANCER THERAPEUTICS

Development and catalytic characterization of L-asparaginase nano-bioconjugates

(2019) Sarika Agrawal et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

l-Asparaginase production in rotating bed reactor from Rhizopus microsporus IBBL-2 using immobilized Ca-alginate beads

(2019) Anup Ashok et al.   3 Biotech

Maltose functionalized magnetic core/shell Fe3O4@Au nanoparticles for an efficient l-asparaginase immobilization

(2019) Tuba Tarhan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The Carboxylated Multi-walled Carbon Nanotubes/l-Asparaginase Doped Calcium-Alginate Beads: Structural and Biocatalytic Characterization

(2019) Ahmet Ulu et al.   CATALYSIS LETTERS

Synthesis, characterization and anticancer activity of β-cyclodextrin-Asparaginase nanobiocomposite on prostate and lymphoma cancer cells

(2019) G. Baskar et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Enzymes immobilized in Langmuir-Blodgett films: Why determining the surface properties in Langmuir monolayer is important?

(2018) LUCIANO CASELI   ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS

Biodegradation of acrylamide by a novel isolate, Cupriavidus oxalaticus ICTDB921: Identification and characterization of the acrylamidase produced

(2018) Dattatray K. Bedade et al.   BIORESOURCE TECHNOLOGY

Integrating enzyme immobilization and protein engineering: An alternative path for the development of novel and improved industrial biocatalysts

(2018) Claudia Bernal et al.   BIOTECHNOLOGY ADVANCES

Glutaminase free l -asparaginase from Vibrio cholerae : Heterologous expression, purification and biochemical characterization

(2018) Remya Radha et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Catalytic characteristics and application of l -asparaginase immobilized on aluminum oxide pellets

(2018) Sarika Agrawal et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Design of epoxy-functionalized Fe 3 O 4 @MCM-41 core–shell nanoparticles for enzyme immobilization

(2018) Ahmet Ulu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Gold nanoparticle mediated delivery of fungal asparaginase against cancer cells

(2018) G. Baskar et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Graphene oxide: An efficient material and recent approach for biotechnological and biomedical applications

(2018) Dinesh Pratap Singh et al.   Materials Science & Engineering C-Materials for Biological Applications

Tubular and Spherical SiO2 Obtained by Sol Gel Method for Lipase Immobilization and Enzymatic Activity

(2018) Crina Anastasescu et al.   MOLECULES

Enhancement in Biological Activity of L-Asparginase by its Conjugation on Silica Nanoparticles

(2018) Dorsa Golestaneh et al.   Recent Patents on Nanotechnology

A General Overview of Support Materials for Enzyme Immobilization: Characteristics, Properties, Practical Utility

(2018) Jakub Zdarta et al.   Catalysts

Chloro-Modified Magnetic Fe3O4@MCM-41 Core–Shell Nanoparticles for L-Asparaginase Immobilization with Improved Catalytic Activity, Reusability, and Storage Stability

(2018) Ahmet Ulu et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Asparaginase conjugated magnetic nanoparticles used for reducing acrylamide formation in food model system

(2018) Shahenvaz Alam et al.   BIORESOURCE TECHNOLOGY

Immobilization of -asparaginase on aspartic acid functionalized graphene oxide nanosheet: Enzyme kinetics and stability studies

(2018) Maryam Monajati et al.   CHEMICAL ENGINEERING JOURNAL

Perspectives and applications of immobilised β-galactosidase in food industry – a review

(2018) Z. Grosová et al.   CZECH JOURNAL OF FOOD SCIENCES

Synthesis, characterization and synergistic activity of cerium-selenium nanobiocomposite of fungal l-asparaginase against lung cancer

(2018) G. Baskar et al.   Materials Science & Engineering C-Materials for Biological Applications

BSA/ASN/Pol407 nanoparticles for acute lymphoblastic leukemia treatment

(2018) Ana Tinoco et al.   BIOCHEMICAL ENGINEERING JOURNAL

Enhanced biocatalytic sustainability of laccase by immobilization on functionalized carbon nanotubes/polysulfone membranes

(2018) João B. Costa et al.   CHEMICAL ENGINEERING JOURNAL

Nanotechnology in Enzyme Immobilization: An overview on enzyme immobilization with nanoparticle matrix

(2018) Kushagri Singh et al.   Current Nanoscience

Further Stabilization of Alcalase Immobilized on Glyoxyl Supports: Amination Plus Modification with Glutaraldehyde

(2018) Fouzia Hussain et al.   MOLECULES

Biochemical characterization of a novel L-asparaginase from Paenibacillus barengoltzii being suitable for acrylamide reduction in potato chips and mooncakes

(2017) Ran Shi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Enzymatic mitigation of acrylamide in fried potato chips using asparaginase from Aspergillus terreus

(2017) Ravi Aiswarya et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY

Different Covalent Immobilizations Modulate Lipase Activities of Hypocrea pseudokoningii

(2017) Marita Pereira et al.   MOLECULES

Enhanced Performance of Magnetic Graphene Oxide-Immobilized Laccase and Its Application for the Decolorization of Dyes

(2017) Jing Chen et al.   MOLECULES

Current applications and different approaches for microbial l-asparaginase production

(2016) Jorge Javier Muso Cachumba et al.   BRAZILIAN JOURNAL OF MICROBIOLOGY

Recent developments in l-asparaginase discovery and its potential as anticancer agent

(2016) Abhinav Shrivastava et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Biochemical characterization and immobilization of Erwinia carotovora l -asparaginase in a microplate for high-throughput biosensing of l -asparagine

(2016) Nikolaos E. Labrou et al.   ENZYME AND MICROBIAL TECHNOLOGY

The use of asparaginase to reduce acrylamide levels in cooked food

(2016) Fei Xu et al.   FOOD CHEMISTRY

Consensus expert recommendations for identification and management of asparaginase hypersensitivity and silent inactivation

(2016) I. M. van der Sluis et al.   HAEMATOLOGICA

Polymeric nanobiocomposites for biomedical applications

(2016) Mohammad Sayem Mozumder et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Metabolic reprogramming of glioblastoma cells by L-asparaginase sensitizes for apoptosis in vitro and in vivo

(2016) Georg Karpel-Massler et al.   Oncotarget

Consensus expert recommendations for identification and management of asparaginase hypersensitivity and silent inactivation

(2016) I. M. van der Sluis et al.   HAEMATOLOGICA

Gold Nanoparticles: Synthesis and Applications in Drug Delivery

(2016) AK Khan et al.   TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH

Impact of polyethylene glycol as additive on the formation and extraction behavior of ionic-liquid based aqueous two-phase system

(2015) Mohammad Vahidnia et al.   AICHE JOURNAL

Applications of commercial biosensors in clinical, food, environmental, and biothreat/biowarfare analyses

(2015) Elif Burcu Bahadır et al.   ANALYTICAL BIOCHEMISTRY

A Comprehensive Review on l-Asparaginase and Its Applications

(2015) Tahira Batool et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

An overview of technologies for immobilization of enzymes and surface analysis techniques for immobilized enzymes

(2015) Nur Royhaila Mohamad et al.   BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT

Strategies for the one-step immobilization–purification of enzymes as industrial biocatalysts

(2015) Oveimar Barbosa et al.   BIOTECHNOLOGY ADVANCES

Nanodevices for the immobilization of therapeutic enzymes

(2015) Valeria E. Bosio et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Reduction of acrylamide level through blanching with treatment by an extremely thermostable l-asparaginase during French fries processing

(2015) Shaohua Zuo et al.   EXTREMOPHILES

A strategy for improving peroxidase stability via immobilization on surface modified multi-walled carbon nanotubes

(2015) Renato M Azevedo et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Laccase immobilization over multi-walled carbon nanotubes: Kinetic, thermodynamic and stability studies

(2015) Ana P.M. Tavares et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Anticancer activity of fungal l-asparaginase conjugated with zinc oxide nanoparticles

(2015) G. Baskar et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Acrylamide: inhibition of formation in processed food and mitigation of toxicity in cells, animals, and humans

(2015) Mendel Friedman   Food & Function

Recent research progress on microbial l-asparaginases

(2014) Shaohua Zuo et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The glutaminase activity of L-asparaginase is not required for anticancer activity against ASNS-negative cells

(2014) W. K. Chan et al.   BLOOD

Asparaginase in the treatment of non-ALL hematologic malignancies

(2014) Ashkan Emadi et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Microbial L-asparaginase as a Potential Therapeutic Agent for the Treatment of Acute Lymphoblastic Leukemia: The Pros and Cons

(2014) Noura El-Ahmady El-Nagga et al.   International Journal of Pharmacology

Nutritionally enhanced wheat-oat bread with reduced acrylamide level

(2014) Z. Ciesarová et al.   Quality Assurance and Safety of Crops & Foods

Novel Epoxy Activated Hydrogels for Solving Lactose Intolerance

(2014) Magdy M. M. Elnashar et al.   Biomed Research International

Asparaginase Erwinia chrysanthemi (Erwinaze®): A Guide to Its Use in Acute Lymphoblastic Leukemia in the USA

(2013) Gillian M. Keating   BIODRUGS

Asparagine synthetase is an independent predictor of surgical survival and a potential therapeutic target in hepatocellular carcinoma

(2013) B Zhang et al.   BRITISH JOURNAL OF CANCER

Reduction of Acrylamide Formation in Sweet Bread with l-Asparaginase Treatment

(2013) N. S. Mohan Kumar et al.   Food and Bioprocess Technology

Nonporous silica nanoparticles for nanomedicine application

(2013) Li Tang et al.   Nano Today

Efficient production of l-asparaginase from Bacillus licheniformis with low-glutaminase activity: Optimization, scale up and acrylamide degradation studies

(2012) Richi V. Mahajan et al.   BIORESOURCE TECHNOLOGY

Gold nanoparticles: Emerging paradigm for targeted drug delivery system

(2012) Anil Kumar et al.   BIOTECHNOLOGY ADVANCES

Kinetic Model for the Formation of Acrylamide during the Finish-Frying of Commercial French Fries

(2012) Jane K. Parker et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

PLGA-based nanoparticles: An overview of biomedical applications

(2012) Fabienne Danhier et al.   JOURNAL OF CONTROLLED RELEASE

Design of double-walled carbon nanotubes for biomedical applications

(2012) V Neves et al.   NANOTECHNOLOGY

Immobilization of commercial laccase on spent grain

(2012) Andreia Machado da Silva et al.   PROCESS BIOCHEMISTRY

Green coconut fiber: a novel carrier for the immobilization of commercial laccase by covalent attachment for textile dyes decolourization

(2012) Raquel O. Cristóvão et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Plant asparaginase-based asparagine biosensor for leukemia

(2012) Kuldeep Kumar et al.   Artificial Cells Nanomedicine and Biotechnology

Gold nanoparticles functionalized with therapeutic and targeted peptides for cancer treatment

(2011) Anil Kumar et al.   BIOMATERIALS

Potential applications of enzymes immobilized on/in nano materials: A review

(2011) Shakeel Ahmed Ansari et al.   BIOTECHNOLOGY ADVANCES

L-Asparaginase and Inhibitors of Glutamine Synthetase Disclose Glutamine Addiction of β-Catenin-Mutated Human Hepatocellular Carcinoma Cells

(2011)   CURRENT CANCER DRUG TARGETS

Gold nanoparticle-based biosensors

(2011) Yuanyuang Li et al.   GOLD BULLETIN

l-Asparaginase Production by Moderate Halophilic Bacteria Isolated from Maharloo Salt Lake

(2011) Alireza Ebrahiminezhad et al.   INDIAN JOURNAL OF MICROBIOLOGY

Engineering substrate specificity of E. carotovora l-asparaginase for the development of biosensor

(2011) Georgia A. Kotzia et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Immobilization of commercial laccase onto green coconut fiber by adsorption and its application for reactive textile dyes degradation

(2011) Raquel O. Cristóvão et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Expanding Targets for a Metabolic Therapy of Cancer: L-Asparaginase

(2011) Daniele Covini et al.   Recent Patents on Anti-Cancer Drug Discovery

Functionalized Gold Nanoparticles and Their Biomedical Applications

(2011) Pooja Tiwari et al.   Nanomaterials

Immobilization of chloroperoxidase onto highly hydrophilic polyethylene chains via bio-conjugation: Catalytic properties and stabilities

(2010) Gulay Bayramoglu et al.   BIORESOURCE TECHNOLOGY

Improved production of l-asparaginase by Bacillus brevis cultivated in the presence of oxygen-vectors

(2010) Umesh Narta et al.   BIORESOURCE TECHNOLOGY

Purification and characterization of glutaminase-free l-asparaginase from Pectobacterium carotovorum MTCC 1428

(2010) Sanjay Kumar et al.   BIORESOURCE TECHNOLOGY

The first characterized asparaginase from a basidiomycete, Flammulina velutipes

(2010) Nadine Eisele et al.   BIORESOURCE TECHNOLOGY

Interfacing Carbon Nanotubes with Living Mammalian Cells and Cytotoxicity Issues

(2010) Hui-Fang Cui et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Production of l-asparaginase from Escherichia coli ATCC 11303: Optimization by response surface methodology

(2010) Seyedeh Laleh Dashtban Kenari et al.   FOOD AND BIOPRODUCTS PROCESSING

Graphene Oxide as a Matrix for Enzyme Immobilization

(2010) Jiali Zhang et al.   LANGMUIR

Cellular Uptake and Nanoscale Localization of Gold Nanoparticles in Cancer Using Label-Free Confocal Raman Microscopy

(2010) Neha B. Shah et al.   MOLECULAR PHARMACEUTICS

Cell-Cycle Inhibition by Helicobacter pylori L-Asparaginase

(2010) Claudia Scotti et al.   PLoS One

Evaluating the Potential for Enzymatic Acrylamide Mitigation in a Range of Food Products Using an Asparaginase from Aspergillus oryzae

(2009) Hanne V. Hendriksen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Mitigation Strategies to Reduce Acrylamide Formation in Fried Potato Products

(2008) Francisco Morales et al.   Annals of the New York Academy of Sciences

Helicobacter pyloril-asparaginase: A promising chemotherapeutic agent

(2008) Donata Cappelletti et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The effect of asparaginase on acrylamide formation in French fries

(2008) Franco Pedreschi et al.   FOOD CHEMISTRY

Bioinspired enzyme encapsulation for biocatalysis

(2008) Lorena Betancor et al.   TRENDS IN BIOTECHNOLOGY