Structure, mechanism, and regulation of mitochondrial DNA transcription initiation

The C-terminal tail of the yeast mitochondrial transcription factor Mtf1 coordinates template strand alignment, DNA scrunching and timely transition into elongation

(2020) Urmimala Basu et al.   NUCLEIC ACIDS RESEARCH

Hypermethylation of mitochondrial DNA in vascular smooth muscle cells impairs cell contractility

(2020) Yue-Feng Liu et al.   Cell Death & Disease

Estrogenic control of mitochondrial function

(2020) Carolyn M. Klinge   Redox Biology

Mitochondrial function in immune cells in health and disease

(2020) M.M. Faas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial Dysfunctions: A Red Thread across Neurodegenerative Diseases

(2020) Serena Stanga et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The C-terminal tails of the mitochondrial transcription factors Mtf1 and TFB2M are part of an autoinhibitory mechanism that regulates DNA binding

(2020) Urmimala Basu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N6-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA

(2020) Ziyang Hao et al.   MOLECULAR CELL

Mitochondria dysfunction in the pathogenesis of Alzheimer’s disease: recent advances

(2020) Wenzhang Wang et al.   Molecular Neurodegeneration

The Mitochondrial Protein VDAC1 at the Crossroads of Cancer Cell Metabolism: The Epigenetic Link

(2020) Zohar Amsalem et al.   Cancers

Phosphorylation of mitochondrial transcription factor B2 controls mitochondrial DNA binding and transcription

(2020) Alicia M. Bostwick et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Alzheimer’s and Parkinson’s brain tissues have reduced expression of genes for mtDNA OXPHOS Proteins, mitobiogenesis regulator PGC-1α protein and mtRNA stabilizing protein LRPPRC (LRP130)

(2020) James P. Bennett et al.   MITOCHONDRION

Mitochondrial dysfunction in metabolic syndrome

(2020) Pankaj Prasun   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The dynamic landscape of transcription initiation in yeast mitochondria

(2020) Byeong-Kwon Sohn et al.   Nature Communications

The mitochondrial retrograde signaling regulates Wnt signaling to promote tumorigenesis in colon cancer

(2019) Yang-An Wen et al.   CELL DEATH AND DIFFERENTIATION

RNase H1 directs origin-specific initiation of DNA replication in human mitochondria

(2019) Viktor Posse et al.   PLoS Genetics

Mitochondrial localization, import and mitochondrial function of the androgen receptor

(2019) Prachi Bajpai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytosine methylation of mitochondrial DNA at CpG sequences impacts transcription factor A DNA binding and transcription

(2019) Vishantie Dostal et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

TEFM regulates both transcription elongation and RNA processing in mitochondria

(2019) Shan Jiang et al.   EMBO REPORTS

LRPPRC: A Multifunctional Protein Involved in Energy Metabolism and Human Disease

(2019) Jie Cui et al.   Frontiers in Physiology

The Mechanisms of Substrate Selection, Catalysis, and Translocation by the Elongating RNA Polymerase

(2019) Georgiy A. Belogurov et al.   JOURNAL OF MOLECULAR BIOLOGY

FoxO1 localizes to mitochondria of adipose tissue and is affected by nutrient stress

(2019) Daniele Lettieri-Barbato et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy

(2019) Piotr K. Kopinski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Mitochondrion as an Emerging Therapeutic Target in Cancer

(2019) Katherine G. Roth et al.   TRENDS IN MOLECULAR MEDICINE

G-quadruplex dynamics contribute to regulation of mitochondrial gene expression

(2019) M. Falabella et al.   Scientific Reports

Hypoxia induces rapid, STAT3 and ROS dependent, mitochondrial translocation of RelA(p65) and IκBα

(2019) Iglika G. Ivanova et al.   BIOSCIENCE REPORTS

Mitochondrial DNA: Epigenetics and environment

(2019) Nidhi Sharma et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

The strand-biased mitochondrial DNA methylome and its regulation by DNMT3A

(2019) Xiaoyang Dou et al.   GENOME RESEARCH

Human mitochondrial DNA is extensively methylated in a non-CpG context

(2019) Vibha Patil et al.   NUCLEIC ACIDS RESEARCH

Testosterone induces up-regulation of mitochondrial gene expression in murine C2C12 skeletal muscle cells accompanied by an increase of nuclear respiratory factor-1 and its downstream effectors

(2019) Lucía Pronsato et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Emerging Role of Mitochondrial DNA as a Major Driver of Inflammation and Disease Progression

(2019) Fei Zhong et al.   TRENDS IN IMMUNOLOGY

The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress

(2018) Kyung Hwa Kim et al.   Cell Metabolism

Potential roles for G-quadruplexes in mitochondria

(2018) Micol Falabella et al.   CURRENT MEDICINAL CHEMISTRY

A common pattern of DNase I footprinting throughout the human mtDNA unveils clues for a chromatin-like organization

(2018) Amit Blumberg et al.   GENOME RESEARCH

Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53

(2018) Giuseppe Arena et al.   MOLECULAR CELL

Acetylation and phosphorylation of human TFAM regulate TFAM–DNA interactions via contrasting mechanisms

(2018) Graeme A King et al.   NUCLEIC ACIDS RESEARCH

Intracellular and Intercellular Signalling Mechanisms following DNA Damage Are Modulated By PINK1

(2018) Mihaela Temelie et al.   Oxidative Medicine and Cellular Longevity

Mitochondrial DNA Transcription and Its Regulation: An Evolutionary Perspective

(2018) Gilad Barshad et al.   TRENDS IN GENETICS

Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy

(2018) Valentina Celestini et al.   Cell Death & Disease

Accurate estimation of 5-methylcytosine in mammalian mitochondrial DNA

(2018) Shigeru Matsuda et al.   Scientific Reports

Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation

(2018) Oswaldo A. Lozoya et al.   PLOS BIOLOGY

Regulation of energy metabolism during early mammalian development: TEAD4 controls mitochondrial transcription

(2018) Ram P. Kumar et al.   DEVELOPMENT

Structural basis of mitochondrial transcription

(2018) Hauke S. Hillen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Modulation of mitochondrial DNA copy number in a model of glioblastoma induces changes to DNA methylation and gene expression of the nuclear genome in tumours

(2018) Xin Sun et al.   Epigenetics & Chromatin

TEFM Enhances Transcription Elongation by Modifying mtRNAP Pausing Dynamics

(2018) Hongwu Yu et al.   BIOPHYSICAL JOURNAL

Highly efficient 5' capping of mitochondrial RNA with NAD+ and NADH by yeast and human mitochondrial RNA polymerase

(2018) Jeremy G Bird et al.   eLife

Cause or casualty: The role of mitochondrial DNA in aging and age-associated disease

(2018) E. Sandra Chocron et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Regulation of mitochondrial gene expression the epigenetic enigma

(2017) Marianne G Rots   Frontiers in Bioscience-Landmark

Differentially expressed mitochondrial genes in breast cancer cells: Potential new targets for anti-cancer therapies

(2017) Qinglin Zhang et al.   GENE

Initiation of mtDNA transcription is followed by pausing, and diverges across human cell types and during evolution

(2017) Amit Blumberg et al.   GENOME RESEARCH

Transcriptional fidelities of human mitochondrial POLRMT, yeast mitochondrial Rpo41, and phage T7 single-subunit RNA polymerases

(2017) Shemaila Sultana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unexpected sequences and structures of mtDNA required for efficient transcription from the first heavy-strand promoter

(2017) Akira Uchida et al.   eLife

Experimental mitochondria-targeted DNA methylation identifies GpC methylation, not CpG methylation, as potential regulator of mitochondrial gene expression

(2017) Monique G. P. van der Wijst et al.   Scientific Reports

Maintenance and Expression of Mammalian Mitochondrial DNA

(2016) Claes M. Gustafsson et al.   Annual Review of Biochemistry

MOF Acetyl Transferase Regulates Transcription and Respiration in Mitochondria

(2016) Aindrila Chatterjee et al.   CELL

Human Mitochondrial Transcription Initiation Complexes Have Similar Topology on the Light and Heavy Strand Promoters

(2016) Yaroslav I. Morozov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Yeast Mitochondrial RNA Polymerase and Transcription Factor Complex Catalyzes Efficient Priming of DNA Synthesis on Single-stranded DNA

(2016) Aparna Ramachandran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Mitochondrial Transcription Factor B2 Is Required for Promoter Melting during Initiation of Transcription

(2016) Viktor Posse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The rise of mitochondria in medicine

(2016) Martin Picard et al.   MITOCHONDRION

Methylation profiling by bisulfite sequencing analysis of the mtDNA Non-Coding Region in replicative and senescent Endothelial Cells

(2016) Valentina Bianchessi et al.   MITOCHONDRION

Mitochondria and Cancer

(2016) Wei-Xing Zong et al.   MOLECULAR CELL

Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53

(2016) Romain Riscal et al.   MOLECULAR CELL

DNA structure directs positioning of the mitochondrial genome packaging protein Abf2p

(2016) Arka Chakraborty et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial transcription termination factor 1 directs polar replication fork pausing

(2016) Yonghong Shi et al.   NUCLEIC ACIDS RESEARCH

Human mitochondrial transcription factors TFAM and TFB2M work synergistically in promoter melting during transcription initiation

(2016) Aparna Ramachandran et al.   NUCLEIC ACIDS RESEARCH

Re-evaluation of G-quadruplex propensity with G4Hunter

(2016) Amina Bedrat et al.   NUCLEIC ACIDS RESEARCH

Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer

(2016) Amanda R. Oran et al.   Oncotarget

Increased Hepatic Fatty Acids Uptake and Oxidation by LRPPRC-Driven Oxidative Phosphorylation Reduces Blood Lipid Levels

(2016) Shi Lei et al.   Frontiers in Physiology

STAT3 Undergoes Acetylation-dependent Mitochondrial Translocation to Regulate Pyruvate Metabolism

(2016) Yan S. Xu et al.   Scientific Reports

SIRT3 Mediates Multi-Tissue Coupling for Metabolic Fuel Switching

(2015) Kristin E. Dittenhafer-Reed et al.   Cell Metabolism

Mitochondrial disorders: Challenges in diagnosis & treatment

(2015) Kumarasamy Thangaraj et al.   INDIAN JOURNAL OF MEDICAL RESEARCH

Mitochondrial Ribosomal Protein L12 Is Required for POLRMT Stability and Exists as Two Forms Generated by Alternative Proteolysis during Import

(2015) Jessica Nouws et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Yeast mitochondrial RNA polymerase primes mitochondrial DNA polymerase at origins of replication and promoter sequences

(2015) Eugenia Sanchez-Sandoval et al.   MITOCHONDRION

Two mechanisms coordinate replication termination by theEscherichia coliTus–Tercomplex

(2015) Manjula Pandey et al.   NUCLEIC ACIDS RESEARCH

TEFM is a potent stimulator of mitochondrial transcription elongation in vitro

(2015) Viktor Posse et al.   NUCLEIC ACIDS RESEARCH

Regulation of DNA replication at the end of the mitochondrial D-loop involves the helicase TWINKLE and a conserved sequence element

(2015) Elisabeth Jemt et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial Retrograde Signaling: Triggers, Pathways, and Outcomes

(2015) Fernanda Marques da Cunha et al.   Oxidative Medicine and Cellular Longevity

Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid

(2015) Christian Kukat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maternal stress predicts altered biogenesis and the profile of mitochondrial proteins in the frontal cortex and hippocampus of adult offspring rats

(2015) Katarzyna Głombik et al.   PSYCHONEUROENDOCRINOLOGY

The thumb subdomain of yeast mitochondrial RNA polymerase is involved in processivity, transcript fidelity and mitochondrial transcription factor binding

(2015) Gilberto Velazquez et al.   RNA Biology

Replication-transcription switch in human mitochondria

(2015) K. Agaronyan et al.   SCIENCE

Negative transcriptional regulation of mitochondrial transcription factor A (TFAM) by nuclear TFAM

(2014) Eun Jin Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Association of G-quadruplex forming sequences with human mtDNA deletion breakpoints

(2014) Dawei W Dong et al.   BMC GENOMICS

In D-loop: 40years of mitochondrial 7S DNA

(2014) Thomas J. Nicholls et al.   EXPERIMENTAL GERONTOLOGY

Replication Intermediates of the Linear Mitochondrial DNA ofCandida parapsilosisSuggest a Common Recombination Based Mechanism for Yeast Mitochondria

(2014) Joachim M. Gerhold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stat3 Binds to mtDNA and Regulates Mitochondrial Gene Expression in Keratinocytes

(2014) Everardo Macias et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

ERK-mediated phosphorylation of TFAM downregulates mitochondrial transcription: Implications for Parkinson's disease

(2014) Kent Z.Q. Wang et al.   MITOCHONDRION

Yeast DEAD Box Protein Mss116p Is a Transcription Elongation Factor That Modulates the Activity of Mitochondrial RNA Polymerase

(2014) D. A. Markov et al.   MOLECULAR AND CELLULAR BIOLOGY

Organization of the human mitochondrial transcription initiation complex

(2014) Elena Yakubovskaya et al.   NUCLEIC ACIDS RESEARCH

Interactions of the yeast mitochondrial RNA polymerase with the +1 and +2 promoter bases dictate transcription initiation efficiency

(2014) Aishwarya P. Deshpande et al.   NUCLEIC ACIDS RESEARCH

Yeast mitochondrial RNAP conformational changes are regulated by interactions with the mitochondrial transcription factor

(2014) Srdja Drakulic et al.   NUCLEIC ACIDS RESEARCH

PhosphoSitePlus, 2014: mutations, PTMs and recalibrations

(2014) Peter V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

A novel intermediate in transcription initiation by human mitochondrial RNA polymerase

(2014) Yaroslav I. Morozov et al.   NUCLEIC ACIDS RESEARCH

Distinct functions of the RNA polymerase σ subunit region 3.2 in RNA priming and promoter escape

(2014) Danil Pupov et al.   NUCLEIC ACIDS RESEARCH

Evidence for Site-Specific Occupancy of the Mitochondrial Genome by Nuclear Transcription Factors

(2014) Georgi K. Marinov et al.   PLoS One

Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation

(2014) Huu B. Ngo et al.   Nature Communications

Mutations in mitochondrial ribosomal protein MRPL12 leads to growth retardation, neurological deterioration and mitochondrial translation deficiency

(2013) Valérie Serre et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

MTERF1 Binds mtDNA to Prevent Transcriptional Interference at the Light-Strand Promoter but Is Dispensable for rRNA Gene Transcription Regulation

(2013) Mügen Terzioglu et al.   Cell Metabolism

TEAD4 establishes the energy homeostasis essential for blastocoel formation

(2013) K. J. Kaneko et al.   DEVELOPMENT

The Control Region of Mitochondrial DNA Shows an Unusual CpG and Non-CpG Methylation Pattern

(2013) D. Bellizzi et al.   DNA RESEARCH

Insights into the Mechanism of Initial Transcription inEscherichia coliRNA Polymerase

(2013) Satamita Samanta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of human mitochondrial RNA polymerase elongation complex

(2013) Kathrin Schwinghammer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Mitochondrial RNA Landscape of Saccharomyces cerevisiae

(2013) Edward M. Turk et al.   PLoS One

Conservation of Promoter Melting Mechanisms in Divergent Regions of the Single-Subunit RNA Polymerases

(2012) Gilberto Velazquez et al.   BIOCHEMISTRY

Mechanism of transcription initiation by the yeast mitochondrial RNA polymerase

(2012) Aishwarya P. Deshpande et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

A Quantitative Map of the Liver Mitochondrial Phosphoproteome Reveals Posttranslational Control of Ketogenesis

(2012) Paul A. Grimsrud et al.   Cell Metabolism

Phosphorylation of Human TFAM in Mitochondria Impairs DNA Binding and Promotes Degradation by the AAA+ Lon Protease

(2012) Bin Lu et al.   MOLECULAR CELL

Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome

(2012) Alexander S. Hebert et al.   MOLECULAR CELL

Structure and function of the initially transcribing RNA polymerase II–TFIIB complex

(2012) Sarah Sainsbury et al.   NATURE

Transcription from the second heavy-strand promoter of human mtDNA is repressed by transcription factor A in vitro

(2012) M. F. Lodeiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional requirements of the distal heavy-strand promoter of mtDNA

(2012) O. Zollo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of Transcription Initiation

(2012) Y. Zhang et al.   SCIENCE

Human mitochondrial transcription factor A functions in both nuclei and mitochondria and regulates cancer cell growth

(2011) Bin Han et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hitting the brakes: Termination of mitochondrial transcription

(2011) Kip E. Guja et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

p53-Dependent Regulation of Mitochondrial Energy Production by the RelA Subunit of NF- B

(2011) R. F. Johnson et al.   CANCER RESEARCH

LRP130 Protein Remodels Mitochondria and Stimulates Fatty Acid Oxidation

(2011) Lijun Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The N-terminal Domain of the Yeast Mitochondrial RNA Polymerase Regulates Multiple Steps of Transcription

(2011) Swaroopa Paratkar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcription Factor-dependent DNA Bending Governs Promoter Recognition by the Mitochondrial RNA Polymerase

(2011) Guo-Qing Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct regulation of complex I by mitochondrial MEF2D is disrupted in a mouse model of Parkinson disease and in human patients

(2011) Hua She et al.   JOURNAL OF CLINICAL INVESTIGATION

Structure of human mitochondrial RNA polymerase

(2011) Rieke Ringel et al.   NATURE

Human mitochondrial transcription factor A induces a U-turn structure in the light strand promoter

(2011) Anna Rubio-Cosials et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The mitochondrial transcription and packaging factor Tfam imposes a U-turn on mitochondrial DNA

(2011) Huu B Ngo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Opening–closing dynamics of the mitochondrial transcription pre-initiation complex

(2011) Hajin Kim et al.   NUCLEIC ACIDS RESEARCH

Transcriptional activation by mitochondrial transcription factor A involves preferential distortion of promoter DNA

(2011) Christopher S. Malarkey et al.   NUCLEIC ACIDS RESEARCH

TEFM (c17orf42) is necessary for transcription of human mtDNA

(2011) Michal Minczuk et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial Ribosomal Protein L12 selectively associates with human mitochondrial RNA polymerase to activate transcription

(2011) Y. V. Surovtseva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maintenance and expression of the S. cerevisiae mitochondrial genome—From genetics to evolution and systems biology

(2010) Kamil A. Lipinski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Helix Unwinding and Base Flipping Enable Human MTERF1 to Terminate Mitochondrial Transcription

(2010) Elena Yakubovskaya et al.   CELL

Human Mitochondrial Transcription Revisited

(2010) Dmitry Litonin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fluorescence-Based Assay to Measure the Real-time Kinetics of Nucleotide Incorporation during Transcription Elongation

(2010) Guo-Qing Tang et al.   JOURNAL OF MOLECULAR BIOLOGY

The End of the Circle for Yeast Mitochondrial DNA

(2010) Arnold J. Bendich   MOLECULAR CELL

Strand Invasion Structures in the Inverted Repeat of Candida albicans Mitochondrial DNA Reveal a Role for Homologous Recombination in Replication

(2010) Joachim M. Gerhold et al.   MOLECULAR CELL

Core human mitochondrial transcription apparatus is a regulated two-component system in vitro

(2010) T. E. Shutt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Lon protease regulates mitochondrial DNA copy number and transcription by selective degradation of mitochondrial transcription factor A (TFAM)

(2010) Y. Matsushima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

(2010) F. Weinberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear transcription factors in mammalian mitochondria

(2010) Sarah Leigh-Brown et al.   GENOME BIOLOGY

Mitochondrial Transcription Factor Mtf1 Traps the Unwound Non-template Strand to Facilitate Open Complex Formation

(2009) Swaroopa Paratkar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Respiratory Factor 2 Induces the Expression of Many but Not All Human Proteins Acting in Mitochondrial DNA Transcription and Replication

(2009) Francesco Bruni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple Functions of Yeast Mitochondrial Transcription Factor Mtf1p during Initiation

(2009) Maria Savkina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53

(2009) Tuck Seng Wong et al.   NUCLEIC ACIDS RESEARCH

Real-time observation of the transition from transcription initiation to elongation of the RNA polymerase

(2009) Guo-Qing Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of proteins associated with the yeast mitochondrial RNA polymerase by tandem affinity purification

(2009) Dmitriy A. Markov et al.   YEAST

The NF- B Family of Transcription Factors and Its Regulation

(2009) A. Oeckinghaus et al.   Cold Spring Harbor Perspectives in Biology

The A3243G tRNALeu(UUR) MELAS mutation causes amino acid misincorporation and a combined respiratory chain assembly defect partially suppressed by overexpression of EFTu and EFG2

(2008) F. Sasarman et al.   HUMAN MOLECULAR GENETICS

Fluorescence Mapping of the Open Complex of Yeast Mitochondrial RNA Polymerase

(2008) Guo-Qing Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcription Initiation in a Single-Subunit RNA Polymerase Proceeds through DNA Scrunching and Rotation of the N-Terminal Subdomains

(2008) Guo-Qing Tang et al.   MOLECULAR CELL

Human mitochondrial RNA polymerase primes lagging-strand DNA synthesis in vitro

(2008) S. Wanrooij et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Structure of a Transcribing T7 RNA Polymerase in Transition from Initiation to Elongation

(2008) K. J. Durniak et al.   SCIENCE