Acetylation and phosphorylation of human TFAM regulate TFAM–DNA interactions via contrasting mechanisms

Unexpected sequences and structures of mtDNA required for efficient transcription from the first heavy-strand promoter

(2017) Akira Uchida et al.   eLife

DNA Twist Stability Changes with Magnesium(2+) Concentration

(2016) Onno D. Broekmans et al.   PHYSICAL REVIEW LETTERS

POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA

(2016) I. Ku hl et al.   Science Advances

A model for transcription initiation in human mitochondria

(2015) Yaroslav I. Morozov et al.   NUCLEIC ACIDS RESEARCH

Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid

(2015) Christian Kukat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allostery through protein-induced DNA bubbles

(2015) Joseph J. Traverso et al.   Scientific Reports

Post-Translational Modifications of Histones That Influence Nucleosome Dynamics

(2014) Gregory D. Bowman et al.   CHEMICAL REVIEWS

ERK-mediated phosphorylation of TFAM downregulates mitochondrial transcription: Implications for Parkinson's disease

(2014) Kent Z.Q. Wang et al.   MITOCHONDRION

Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation

(2014) Huu B. Ngo et al.   Nature Communications

In Vitro-Reconstituted Nucleoids Can Block Mitochondrial DNA Replication and Transcription

(2014) Géraldine Farge et al.   Cell Reports

PICH: A DNA Translocase Specially Adapted for Processing Anaphase Bridge DNA

(2013) Andreas Biebricher et al.   MOLECULAR CELL

Genome-Wide Analysis Reveals Coating of the Mitochondrial Genome by TFAM

(2013) Yun E. Wang et al.   PLoS One

mtDNA makes a U-turn for the mitochondrial nucleoid

(2013) Christian Kukat et al.   TRENDS IN CELL BIOLOGY

Phosphorylation of Human TFAM in Mitochondria Impairs DNA Binding and Promotes Degradation by the AAA+ Lon Protease

(2012) Bin Lu et al.   MOLECULAR CELL

Single-molecule kinetics reveal microscopic mechanism by which High-Mobility Group B proteins alter DNA flexibility

(2012) Micah J. McCauley et al.   NUCLEIC ACIDS RESEARCH

The high mobility group box: the ultimate utility player of a cell

(2012) Christopher S. Malarkey et al.   TRENDS IN BIOCHEMICAL SCIENCES

Protein sliding and DNA denaturation are essential for DNA organization by human mitochondrial transcription factor A

(2012) Géraldine Farge et al.   Nature Communications

Human mitochondrial transcription factor A induces a U-turn structure in the light strand promoter

(2011) Anna Rubio-Cosials et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The mitochondrial transcription and packaging factor Tfam imposes a U-turn on mitochondrial DNA

(2011) Huu B Ngo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Transcriptional activation by mitochondrial transcription factor A involves preferential distortion of promoter DNA

(2011) Christopher S. Malarkey et al.   NUCLEIC ACIDS RESEARCH

Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA

(2011) C. Kukat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human mitochondrial transcription factor A is required for the segregation of mitochondrial DNA in cultured cells

(2010) Katsumi Kasashima et al.   EXPERIMENTAL CELL RESEARCH

Human Mitochondrial Transcription Revisited

(2010) Dmitry Litonin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Core human mitochondrial transcription apparatus is a regulated two-component system in vitro

(2010) T. E. Shutt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein-binding assays in biological liquids using microscale thermophoresis

(2010) Christoph J. Wienken et al.   Nature Communications

TFB2 Is a Transient Component of the Catalytic Site of the Human Mitochondrial RNA Polymerase

(2009) Marina Sologub et al.   CELL

Nonspecifically bound proteins spin while diffusing along DNA

(2009) Paul C Blainey et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53

(2009) Tuck Seng Wong et al.   NUCLEIC ACIDS RESEARCH

Structural analysis and DNA binding of the HMG domains of the human mitochondrial transcription factor A

(2009) Todd A. Gangelhoff et al.   NUCLEIC ACIDS RESEARCH

Alterations in mitochondrial function and cytosolic calcium induced by hyperglycemia are restored by mitochondrial transcription factor A in cardiomyocytes

(2008) Jorge Suarez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Spontaneous NA+transients in individual mitochondria of intact astrocytes

(2007) Guillaume Azarias et al.   GLIA