Can SARS-CoV-2 Virus Use Multiple Receptors to Enter Host Cells?

Development of epitope‐based peptide vaccine against novel coronavirus 2019 (SARS‐COV‐2): Immunoinformatics approach

(2020) Manojit Bhattacharya et al.   JOURNAL OF MEDICAL VIROLOGY

Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS

(2020) Yushun Wan et al.   JOURNAL OF VIROLOGY

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

(2020) Roujian Lu et al.   LANCET

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

(2020) Nanshan Chen et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury

(2020) Yingxia Liu et al.   Science China-Life Sciences

DNGR-1, a Dendritic Cell-Specific Sensor of Tissue Damage That Dually Modulates Immunity and Inflammation

(2020) Francisco J. Cueto et al.   Frontiers in Immunology

Continuing versus suspending angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: Impact on adverse outcomes in hospitalized patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

(2020) Renato D. Lopes et al.   AMERICAN HEART JOURNAL

Toll-like Receptors and the Control of Immunity

(2020) Katherine A. Fitzgerald et al.   CELL

Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2

(2020) Qihui Wang et al.   CELL

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Clinical characteristics of asymptomatic and symptomatic patients with mild COVID-19

(2020) G.-u. Kim et al.   CLINICAL MICROBIOLOGY AND INFECTION

SARS-CoV-2 and DPP4 inhibition: Is it time to pray for Janus Bifrons?

(2020) Dario Pitocco et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

DPP4 inhibition: preventing SARS‐CoV ‐2 infection and/or progression of COVID ‐19?

(2020) Rocky Strollo et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

The pivotal link between ACE2 deficiency and SARS-CoV-2 infection

(2020) Paolo Verdecchia et al.   European Journal of Internal Medicine

Nasal Gene Expression of Angiotensin-Converting Enzyme 2 in Children and Adults

(2020) Supinda Bunyavanich et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Suppressed T cell-mediated immunity in patients with COVID-19: A clinical retrospective study in Wuhan, China

(2020) Bo XU et al.   JOURNAL OF INFECTION

COVID-19 spike-host cell receptor GRP78 binding site prediction

(2020) Ibrahim M. Ibrahim et al.   JOURNAL OF INFECTION

DC/L‐SIGNs of Hope in the COVID‐19 Pandemic

(2020) Adam Brufsky et al.   JOURNAL OF MEDICAL VIROLOGY

In silico studies on the comparative characterization of the interactions of SARS‐CoV‐2 spike glycoprotein with ACE‐2 receptor homologs and human TLRs

(2020) Abhigyan Choudhury et al.   JOURNAL OF MEDICAL VIROLOGY

Hypothesis: angiotensin-converting enzyme inhibitors and angiotensin receptor blockers may increase the risk of severe COVID-19

(2020) James H Diaz   JOURNAL OF TRAVEL MEDICINE

Bioinformatic analysis and identification of single-stranded RNA sequences recognized by TLR7/8 in the SARS-CoV-2, SARS-CoV, and MERS-CoV genomes

(2020) Mario Adán Moreno-Eutimio et al.   MICROBES AND INFECTION

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

(2020) Jun Lan et al.   NATURE

If the world fails to protect the economy, COVID-19 will damage health not just now but also in the future

(2020) Martin McKee et al.   NATURE MEDICINE

Prediction of severe illness due to COVID-19 based on an analysis of initial Fibrinogen to Albumin Ratio and Platelet count

(2020) Xiaojie Bi et al.   PLATELETS

Cell entry mechanisms of SARS-CoV-2

(2020) Jian Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coronavirus Disease 2019 (COVID‐19): Do Angiotensin‐Converting Enzyme Inhibitors/Angiotensin Receptor Blockers Have a Biphasic Effect?

(2020) Rami Sommerstein et al.   Journal of the American Heart Association

Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development

(2020) Eun Kim et al.   EBioMedicine

Dipeptidyl peptidase-4 (DPP4) inhibition in COVID-19

(2020) Sebastiano Bruno Solerte et al.   ACTA DIABETOLOGICA

COVID-19 Severity Correlates with Weaker T Cell Immunity, Hypercytokinemia and Lung Epithelium Injury

(2020) Zhongfang Wang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Presence of antiphospholipid antibodies in COVID-19: case series study

(2020) Luis M Amezcua-Guerra et al.   ANNALS OF THE RHEUMATIC DISEASES

Antiviral activities of type I interferons to SARS-CoV-2 infection

(2020) Emily Mantlo et al.   ANTIVIRAL RESEARCH

Making Sense of Mutation: What D614G Means for the COVID-19 Pandemic Remains Unclear

(2020) Nathan D. Grubaugh et al.   CELL

Elevated calprotectin and abnormal myeloid cell subsets discriminate severe from mild COVID-19

(2020) Aymeric Silvin et al.   CELL

Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis

(2020) Ana Campos Codo et al.   Cell Metabolism

Elevated serum levels of S100A8/A9 and HMGB1 at hospital admission are correlated with inferior clinical outcomes in COVID-19 patients

(2020) Liting Chen et al.   Cellular & Molecular Immunology

COVID‐19—Associated dyslipidemia: Implications for mechanism of impaired resolution and novel therapeutic approaches

(2020) Alexander V. Sorokin et al.   FASEB JOURNAL

Effects of Renin-Angiotensin Inhibition on ACE2 and TMPRSS2 Expression: Insights into COVID-19

(2020) Congqing Wu et al.   HYPERTENSION

Acute SARS-CoV-2 Infection Impairs Dendritic Cell and T Cell Responses

(2020) Runhong Zhou et al.   IMMUNITY

COVID 19: a clue from innate immunity

(2020) Domenico Birra et al.   IMMUNOLOGIC RESEARCH

Presence of Genetic Variants Among Young Men With Severe COVID-19

(2020) Caspar I. van der Made et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Chilblain-like acral lesions during the COVID-19 pandemic (“COVID toes”): Histologic, immunofluorescence, and immunohistochemical study of 17 cases

(2020) Jean Kanitakis et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Cardiovascular disease and COVID ‐19: Australian and New Zealand consensus statement

(2020) Sarah Zaman et al.   MEDICAL JOURNAL OF AUSTRALIA

Different Hypercoagulable Profiles in Patients with COVID-19 Admitted to the Internal Medicine Ward and the Intensive Care Unit

(2020) Luca Spiezia et al.   THROMBOSIS AND HAEMOSTASIS

TLR2 on blood monocytes senses dengue virus infection and its expression correlates with disease pathogenesis

(2020) José A. Aguilar-Briseño et al.   Nature Communications

SARS-CoV-2 is transmitted via contact and via the air between ferrets

(2020) Mathilde Richard et al.   Nature Communications

Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein

(2020) Andrew D. Davidson et al.   Genome Medicine

DPP-4 Inhibitors in the Prevention/Treatment of Pulmonary Fibrosis, Heart and Kidney Injury Caused by COVID-19—A Therapeutic Approach of Choice in Type 2 Diabetic Patients?

(2020) Andrija Smelcerovic et al.   Frontiers in Pharmacology

Possible role of vitamin D in Covid-19 infection in pediatric population

(2020) F. M. Panfili et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Preliminary Virtual Screening Studies to Identify GRP78 Inhibitors Which May Interfere with SARS-CoV-2 Infection

(2020) Andreia Palmeira et al.   Pharmaceuticals

Imiquimod - A toll like receptor 7 agonist - Is an ideal option for management of COVID 19

(2020) Athina Angelopoulou et al.   ENVIRONMENTAL RESEARCH

Type I interferon susceptibility distinguishes SARS-CoV-2 from SARS-CoV.

(2020) Kumari G. Lokugamage et al.   JOURNAL OF VIROLOGY

Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates

(2020) Joana Damas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuropilin-1 is a host factor for SARS-CoV-2 infection

(2020) James L. Daly et al.   SCIENCE

Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity

(2020) Ludovico Cantuti-Castelvetri et al.   SCIENCE

The sequence at Spike S1/S2 site enables cleavage by furin and phospho-regulation in SARS-CoV2 but not in SARS-CoV1 or MERS-CoV

(2020) Mihkel Örd et al.   Scientific Reports

Anti-Phospholipid Antibodies in COVID-19 Are Different From Those Detectable in the Anti-Phospholipid Syndrome

(2020) Maria Orietta Borghi et al.   Frontiers in Immunology

Beyond Shielding: The Roles of Glycans in the SARS-CoV-2 Spike Protein

(2020) Lorenzo Casalino et al.   ACS Central Science

Nicotine Modulates MyD88-Dependent Signaling Pathway in Macrophages during Mycobacterial Infection

(2020) Dania AlQasrawi et al.   Microorganisms

Intranasal and epicutaneous administration of Toll-like receptor 7 (TLR7) agonists provides protection against influenza A virus-induced morbidity in mice

(2019) Eunice E. To et al.   Scientific Reports

The coexistence of hypertension and angiotensin II on the risk of coronary heart disease: a population-based prospective cohort study among Inner Mongolians in China

(2019) Yiting Zhou et al.   CURRENT MEDICAL RESEARCH AND OPINION

Exploitation of glycosylation in enveloped virus pathobiology

(2019) Yasunori Watanabe et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes

(2019) Rudragouda Channappanavar et al.   JOURNAL OF CLINICAL INVESTIGATION

Protection against influenza infection requires early recognition by inflammatory dendritic cells through C-type lectin receptor SIGN-R1

(2019) Miguel Palomino-Segura et al.   Nature Microbiology

Toll-like receptor 5 agonist flagellin reduces influenza A virus replication independently of type I interferon and interleukin 22 and improves antiviral efficacy of oseltamivir

(2019) Anne-France Georgel et al.   ANTIVIRAL RESEARCH

Activation of C-type lectin receptor and (RIG)-I-like receptors contributes to proinflammatory response in MERS coronavirus infected macrophages

(2019) Xiaoyu Zhao et al.   JOURNAL OF INFECTIOUS DISEASES

The immunogenic potential of bacterial flagella for Salmonella ‐mediated tumor therapy

(2019) Sebastian Felgner et al.   INTERNATIONAL JOURNAL OF CANCER

N-glycosylation-defective splice variants of neuropilin-1 promote metastasis by activating endosomal signals

(2019) Xiuping Huang et al.   Nature Communications

The novel small-molecule antagonist MMG-11 preferentially inhibits TLR2/1 signaling

(2019) Maria Grabowski et al.   BIOCHEMICAL PHARMACOLOGY

CLEC2 and CLEC5A: Pathogenic Host Factors in Acute Viral Infections

(2019) Pei-Shan Sung et al.   Frontiers in Immunology

Synthetic glycan-based TLR4 agonists targeting caspase-4/11 for the development of adjuvants and immunotherapeutics

(2018) Florian Adanitsch et al.   Chemical Science

C-Type Lectin Receptors in Antiviral Immunity and Viral Escape

(2018) Marta Bermejo-Jambrina et al.   Frontiers in Immunology

Toll-like Receptor 3 is a Therapeutic Target for Pulmonary Hypertension

(2018) Daniela Farkas et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Danger-Associated Molecular Patterns (DAMPs): the Derivatives and Triggers of Inflammation

(2018) Seema Patel   CURRENT ALLERGY AND ASTHMA REPORTS

The fungal ligand chitin directly binds TLR2 and triggers inflammation dependent on oligomer size

(2018) Katharina Fuchs et al.   EMBO REPORTS

Expression of the axon-guidance protein receptor Neuropilin 1 is increased in the spinal cord and decreased in muscle of a mouse model of amyotrophic lateral sclerosis

(2018) Sonja Körner et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The Role of Toll-Like Receptors in the Production of Cytokines by Human Lung Macrophages

(2018) Stanislas Grassin-Delyle et al.   Journal of Innate Immunity

C-type lectin receptor LSECtin-mediated apoptotic cell clearance by macrophages directs intestinal repair in experimental colitis

(2018) Zaopeng Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Analyses of Toll-like Receptor 7 Reveal Detailed RNA Sequence Specificity and Recognition Mechanism of Agonistic Ligands

(2018) Zhikuan Zhang et al.   Cell Reports

The levels of DNGR-1 and its ligand-bearing cells were altered after human and simian immunodeficiency virus infection

(2017) Wen-Rong Yao et al.   IMMUNOLOGIC RESEARCH

Role of scavenger receptors as damage-associated molecular pattern receptors in Toll-like receptor activation

(2017) Kyoko Komai et al.   INTERNATIONAL IMMUNOLOGY

Mechanism of pathogen recognition by human dectin-2

(2017) Hadar Feinberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small-molecule inhibition of TLR8 through stabilization of its resting state

(2017) Shuting Zhang et al.   Nature Chemical Biology

Candida albicans-derived mannoproteins activate NF-κB in reporter cells expressing TLR4, MD2 and CD14

(2017) Traci Ness et al.   PLoS One

Renin-Angiotensin System in Diabetes

(2017) Johannes Rein et al.   PROTEIN AND PEPTIDE LETTERS

Inhibition of Toll-Like Receptor Signaling as a Promising Therapy for Inflammatory Diseases: A Journey from Molecular to Nano Therapeutics

(2017) Wei Gao et al.   Frontiers in Physiology

A conserved TLR5 binding and activation hot spot on flagellin

(2017) Wan Seok Song et al.   Scientific Reports

Bioorthogonal Copper Free Click Chemistry for Labeling and Tracking of Chondrocytes In Vivo

(2016) Hwa In Yoon et al.   BIOCONJUGATE CHEMISTRY

Pulmonary vascular inflammation: effect of TLR signalling on angiopoietin/TIE regulation

(2016) Tobias Hilbert et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Double-Stranded RNA Interacts With Toll-Like Receptor 3 in Driving the Acute Inflammatory Response Following Lung Contusion

(2016) Madathilparambil V. Suresh et al.   CRITICAL CARE MEDICINE

The Molecular Chaperone GRP78 Contributes to Toll-like Receptor 3-mediated Innate Immune Response to Hepatitis C Virus in Hepatocytes

(2016) Dahai Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Particulate β-glucans synergistically activate TLR4 and Dectin-1 in human dendritic cells

(2016) Neha M. Sahasrabudhe et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Neuropilin-1 mediates vascular permeability independently of vascular endothelial growth factor receptor-2 activation

(2016) Lise Roth et al.   Science Signaling

Neuropilin-1 mediates vascular permeability independently of vascular endothelial growth factor receptor-2 activation

(2016) Lise Roth et al.   Science Signaling

IκBζ Regulates Human Monocyte Pro-Inflammatory Responses Induced by Streptococcus pneumoniae

(2016) Kruthika Sundaram et al.   PLoS One

House Dust Mite Allergens and the Induction of Monocyte Interleukin 1β Production That Triggers an IκBζ-Dependent Granulocyte Macrophage Colony-Stimulating Factor Release from Human Lung Epithelial Cells

(2015) Kruthika Sundaram et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Anti-BDCA2 monoclonal antibody inhibits plasmacytoid dendritic cell activation through Fc-dependent and Fc-independent mechanisms

(2015) A. Pellerin et al.   EMBO Molecular Medicine

Protective effects of polydatin on lipopolysaccharide-induced acute lung injury through TLR4-MyD88-NF-κB pathway

(2015) Qi Jiang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cutting Edge: Ezrin Regulates Inflammation by Limiting B Cell IL-10 Production

(2015) Debasis Pore et al.   JOURNAL OF IMMUNOLOGY

Inclusion of Flagellin during Vaccination against Influenza Enhances Recall Responses in Nonhuman Primate Neonates

(2015) Jong R. Kim et al.   JOURNAL OF VIROLOGY

Toll-like receptor 8 senses degradation products of single-stranded RNA

(2015) Hiromi Tanji et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance

(2015) Rajesh Rajaiah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Indirect Toll-like receptor 5-mediated activation of conventional dendritic cells promotes the mucosal adjuvant activity of flagellin in the respiratory tract

(2015) Delphine Fougeron et al.   VACCINE

Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection

(2015) Allison L. Totura et al.   mBio

Toll-like receptor 8 senses degradation products of single-stranded RNA

(2015) Hiromi Tanji et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Expression profiling and functional analysis of Toll-like receptors in primary healthy human nasal epithelial cells shows no correlation and a refractory LPS response

(2015) J. van Tongeren et al.   Clinical and Translational Allergy

Toll-Like Receptor 7 Agonist Imiquimod in Combination with Influenza Vaccine Expedites and Augments Humoral Immune Responses against Influenza A(H1N1)pdm09 Virus Infection in BALB/c Mice

(2014) Anna J. X. Zhang et al.   Clinical and Vaccine Immunology

C-Type Lectin-like Receptor LOX-1 Promotes Dendritic Cell-Mediated Class-Switched B Cell Responses

(2014) HyeMee Joo et al.   IMMUNITY

Lipopeptides are signaled by Toll-like receptor 1, 2 and 6 in endolysosomes

(2014) Y. Motoi et al.   INTERNATIONAL IMMUNOLOGY

The Adjuvanticity of a Mannosylated Antigen Reveals TLR4 Functionality Essential for Subset Specialization and Functional Maturation of Mouse Dendritic Cells

(2014) K.-C. Sheng et al.   JOURNAL OF IMMUNOLOGY

TLR Expression on Neutrophils at the Pulmonary Site of Infection: TLR1/TLR2-Mediated Up-Regulation of TLR5 Expression in Cystic Fibrosis Lung Disease

(2014) B. Koller et al.   JOURNAL OF IMMUNOLOGY

Ezrin Is a Component of the HIV-1 Virological Presynapse and Contributes to the Inhibition of Cell-Cell Fusion

(2014) N. H. Roy et al.   JOURNAL OF VIROLOGY

Toll-Like Receptor 2-Mediated Innate Immune Responses against Junín Virus in Mice Lead to Antiviral Adaptive Immune Responses during Systemic Infection and Do Not Affect Viral Replication in the Brain

(2014) Christian D. Cuevas et al.   JOURNAL OF VIROLOGY

The role of TLR8 signaling in acute myeloid leukemia differentiation

(2014) J J Ignatz-Hoover et al.   LEUKEMIA

Functional Effects of Toll-Like Receptor (TLR)3, 7, 9, RIG-I and MDA-5 Stimulation in Nasal Epithelial Cells

(2014) Lotta Tengroth et al.   PLoS One

Discovery and Characterization of Alamandine

(2013) Roberto Queiroga Lautner et al.   CIRCULATION RESEARCH

Mapping of TLR5 and TLR7 in central and distal human airways and identification of reduced TLR expression in severe asthma

(2013) M. M. Shikhagaie et al.   CLINICAL AND EXPERIMENTAL ALLERGY

NMR study of short β(1-3)-glucans provides insights into the structure and interaction with Dectin-1

(2013) Shinya Hanashima et al.   GLYCOCONJUGATE JOURNAL

Spatial Coupling of JNK Activation to the B Cell Antigen Receptor by Tyrosine-Phosphorylated Ezrin

(2013) N. Parameswaran et al.   JOURNAL OF IMMUNOLOGY

Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26

(2013) Guangwen Lu et al.   NATURE

Key roles of adjuvants in modern vaccines

(2013) Steven G Reed et al.   NATURE MEDICINE

Binding of DC-SIGN to the Hemagglutinin of Influenza A Viruses Supports Virus Replication in DC-SIGN Expressing Cells

(2013) Marine L. B. Hillaire et al.   PLoS One

Ligand Binding and Signaling of Dendritic Cell Immunoreceptor (DCIR) Is Modulated by the Glycosylation of the Carbohydrate Recognition Domain

(2013) Karien Bloem et al.   PLoS One

Roles for Treg Expansion and HMGB1 Signaling through the TLR1-2-6 Axis in Determining the Magnitude of the Antigen-Specific Immune Response to MVA85A

(2013) Magali Matsumiya et al.   PLoS One

TLR2 Ligands Induce NF-κB Activation from Endosomal Compartments of Human Monocytes

(2013) Karim J. Brandt et al.   PLoS One

Lung CD8+ T cells in COPD have increased expression of bacterial TLRs

(2013) Christine M Freeman et al.   RESPIRATORY RESEARCH

Involvement of TLR7 MyD88-dependent signaling pathway in the pathogenesis of adult-onset Still's disease

(2013) Der-Yuan Chen et al.   ARTHRITIS RESEARCH & THERAPY

Toll-like receptor 3 recognizes incomplete stem structures in single-stranded viral RNA

(2013) Megumi Tatematsu et al.   Nature Communications

Viral Toll Like Receptor activation of pulmonary vascular smooth muscle cells results in endothelin-1 generation; relevance to pathogenesis of pulmonary arterial hypertension

(2012) Peter M. George et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The C-type lectin receptor CLEC9A mediates antigen uptake and (cross-)presentation by human blood BDCA3+ myeloid dendritic cells

(2012) G. Schreibelt et al.   BLOOD

HCV glycoprotein E2 is a novel BDCA-2 ligand and acts as an inhibitor of IFN production by plasmacytoid dendritic cells

(2012) J. Florentin et al.   BLOOD

NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system

(2012) Charlotte H. Maden et al.   DEVELOPMENTAL BIOLOGY

Direct Interactions between Calcitonin-Like Receptor (CLR) and CGRP-Receptor Component Protein (RCP) Regulate CGRP Receptor Signaling

(2012) Sophie C. Egea et al.   ENDOCRINOLOGY

Role of human TLR4 in respiratory syncytial virus-induced NF-κB activation, viral entry and replication

(2012) Nico Marr et al.   Innate Immunity

High Mobility Group Box 1 Inhibits Human Pulmonary Artery Endothelial Cell Migration via a Toll-like Receptor 4- and Interferon Response Factor 3-dependent Mechanism(s)

(2012) Eileen M. Bauer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intranasal Treatment with Poly(I{middle dot}C) Protects Aged Mice from Lethal Respiratory Virus Infections

(2012) J. Zhao et al.   JOURNAL OF VIROLOGY

Isolated Toll-like Receptor Transmembrane Domains Are Capable of Oligomerization

(2012) James I. Godfroy et al.   PLoS One

Ezrin Interacts with the SARS Coronavirus Spike Protein and Restrains Infection at the Entry Stage

(2012) Jean Kaoru Millet et al.   PLoS One

Interactions Between Commensal Fungi and the C-Type Lectin Receptor Dectin-1 Influence Colitis

(2012) I. D. Iliev et al.   SCIENCE

The role of dendritic cells in the innate recognition of pathogenic fungi (A. fumigatus,C. neoformansandC. albicans)

(2012) Zaida G. Ramirez-Ortiz et al.   Virulence

Antiphospholipid antibodies induce translocation of TLR7 and TLR8 to the endosome in human monocytes and plasmacytoid dendritic cells

(2011) N. Prinz et al.   BLOOD

CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

(2011) Ivan Zanoni et al.   CELL

Innate Immune Responses to Bacterial Ligands in the Peripheral Human Lung – Role of Alveolar Epithelial TLR Expression and Signalling

(2011) Andrew J. Thorley et al.   PLoS One

Fungal recognition is mediated by the association of dectin-1 and galectin-3 in macrophages

(2011) A. Esteban et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endoplasmic reticulum stress increases the expression and function of toll-like receptor-2 in epithelial cells

(2010) Shogo Shimasaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Legionella pneumophila-induced I B -dependent expression of interleukin-6 in lung epithelium

(2010) J. Lorenz et al.   EUROPEAN RESPIRATORY JOURNAL

Survey of immune-related, mannose/fucose-binding C-type lectin receptors reveals widely divergent sugar-binding specificities

(2010) R. T. Lee et al.   GLYCOBIOLOGY

Use of defined TLR ligands as adjuvants within human vaccines

(2010) Malcolm S. Duthie et al.   IMMUNOLOGICAL REVIEWS

Macrophage Receptors for Influenza A Virus: Role of the Macrophage Galactose-Type Lectin and Mannose Receptor in Viral Entry

(2010) J. P. Upham et al.   JOURNAL OF VIROLOGY

Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses

(2010) M. Ritter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of ovine TLR7 and TLR8 protein coding regions, detection of mutations and Maedi Visna virus infection

(2010) Ivan Mikula et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

A Recombinant Flagellin-Poxvirus Fusion Protein Vaccine Elicits Complement-Dependent Protection Against Respiratory Challenge with Vaccinia Virus in Mice

(2010) Kristen N. Delaney et al.   VIRAL IMMUNOLOGY

Role of the Unfolded Protein Response Regulator GRP78/BiP in Development, Cancer, and Neurological Disorders

(2009) Miao Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

CLEC-2 is an essential platelet-activating receptor in hemostasis and thrombosis

(2009) F. May et al.   BLOOD

TLR7 and TLR8 ligands and antiphospholipid antibodies show synergistic effects on the induction of IL-1β and caspase-1 in monocytes and dendritic cells

(2009) Julia Hurst et al.   IMMUNOBIOLOGY

Human antiphospholipid antibodies induce TNFα in monocytes via Toll-like receptor 8

(2009) Yvonne Döring et al.   IMMUNOBIOLOGY

Interaction between Ebola Virus Glycoprotein and Host Toll-Like Receptor 4 Leads to Induction of Proinflammatory Cytokines and SOCS1

(2009) A. Okumura et al.   JOURNAL OF VIROLOGY

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells

(2009) Giuseppe Mancuso et al.   NATURE IMMUNOLOGY

Homology modeling of human Toll-like receptors TLR7, 8, and 9 ligand-binding domains

(2009) Tiandi Wei et al.   PROTEIN SCIENCE

Characterization of the Interferon-Producing Cell in Mice Infected with Listeria monocytogenes

(2009) Silvia Stockinger et al.   PLoS Pathogens

The C-type lectin surface receptor DCIR acts as a new attachment factor for HIV-1 in dendritic cells and contributes to trans- and cis-infection pathways

(2008) A. A. Lambert et al.   BLOOD

Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-  production

(2008) F. Meyer-Wentrup et al.   BLOOD

Delivery of antigen using a novel mannosylated dendrimer potentiates immunogenicityin vitro andin vivo

(2008) Kuo-Ching Sheng et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Oxidised LDL internalisation by the LOX-1 scavenger receptor is dependent on a novel cytoplasmic motif and is regulated by dynamin-2

(2008) J. E. Murphy et al.   JOURNAL OF CELL SCIENCE

DCIR is endocytosed into human dendritic cells and inhibits TLR8-mediated cytokine production

(2008) Friederike Meyer-Wentrup et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Respiratory Syncytial Virus Activates Innate Immunity through Toll-Like Receptor 2

(2008) M. R. Murawski et al.   JOURNAL OF VIROLOGY

Human TLR1 Deficiency Is Associated with Impaired Mycobacterial Signaling and Protection from Leprosy Reversal Reaction

(2008) Elizabeth A. Misch et al.   PLoS Neglected Tropical Diseases