C-Type Lectin Receptors in Antiviral Immunity and Viral Escape

C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells

(2017) Anthony Troegeler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myeloid C-Type Lectin Receptors in Viral Recognition and Antiviral Immunity

(2017) João Monteiro et al.   Viruses-Basel

Human macrophages differentiated in the presence of vitamin D3 restrict dengue virus infection and innate responses by downregulating mannose receptor expression

(2017) John F. Arboleda Alzate et al.   PLoS Neglected Tropical Diseases

A pH‐ and ionic strength‐dependent conformational change in the neck region regulates DNGR‐1 function in dendritic cells

(2016) Pavel Hanč et al.   EMBO JOURNAL

The mannose receptor negatively modulates the Toll-like receptor 4–aryl hydrocarbon receptor–indoleamine 2,3-dioxygenase axis in dendritic cells affecting T helper cell polarization

(2016) Fabián Salazar et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CLEC5A-Mediated Enhancement of the Inflammatory Response in Myeloid Cells Contributes to Influenza Virus Pathogenicity In Vivo

(2016) Ooiean Teng et al.   JOURNAL OF VIROLOGY

Receptor usage dictates HIV-1 restriction by human TRIM5α in dendritic cell subsets

(2016) Carla M. S. Ribeiro et al.   NATURE

HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3

(2016) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Langerin-mediated internalization of a modified peptide routes antigens to early endosomes and enhances cross-presentation by human Langerhans cells

(2015) Cynthia M Fehres et al.   Cellular & Molecular Immunology

Cross-presentation through langerin and DC-SIGN targeting requires different formulations of glycan-modified antigens

(2015) Cynthia M. Fehres et al.   JOURNAL OF CONTROLLED RELEASE

Dermal CD14 + Dendritic Cell and Macrophage Infection by Dengue Virus Is Stimulated by Interleukin-4

(2015) Evelyne Schaeffer et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The C-type Lectin Langerin Functions as a Receptor for Attachment and Infectious Entry of Influenza A Virus

(2015) Wy Ching Ng et al.   JOURNAL OF VIROLOGY

DCIR negatively regulates CpG-ODN-induced IL-1β and IL-6 production

(2015) Xibao Zhao et al.   MOLECULAR IMMUNOLOGY

HIV-1 immune activation induces Siglec-1 expression and enhances viral trans-infection in blood and tissue myeloid cells

(2015) Maria Pino et al.   Retrovirology

Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination

(2015) P. Robert Beatty et al.   Science Translational Medicine

Complement-Opsonized HIV-1 Overcomes Restriction in Dendritic Cells

(2015) Wilfried Posch et al.   PLoS Pathogens

Complement System Part II: Role in Immunity

(2015) Nicolas S. Merle et al.   Frontiers in Immunology

Measles Virus Suppresses RIG-I-like Receptor Activation in Dendritic Cells via DC-SIGN-Mediated Inhibition of PP1 Phosphatases

(2014) Annelies W. Mesman et al.   Cell Host & Microbe

C-type lectin receptor SIGNR1 expressed on peritoneal phagocytic cells with an immature dendritic cell-like phenotype is involved in uptake of oligomannose-coated liposomes and subsequent cell maturation

(2014) Yoko Kawauchi et al.   CELLULAR IMMUNOLOGY

T Follicular Helper Cell Differentiation, Function, and Roles in Disease

(2014) Shane Crotty   IMMUNITY

Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression

(2014) Netanya G. Sandler et al.   NATURE

Fucose-specific DC-SIGN signalling directs T helper cell type-2 responses via IKKε- and CYLD-dependent Bcl3 activation

(2014) Sonja I. Gringhuis et al.   Nature Communications

Fucose-based PAMPs prime dendritic cells for follicular T helper cell polarization via DC-SIGN-dependent IL-27 production

(2014) Sonja I. Gringhuis et al.   Nature Communications

The ins-and-outs of endosomal antigens for cross-presentation

(2013) Verena Schuette et al.   CURRENT OPINION IN IMMUNOLOGY

Toll-Like Receptors in Antiviral Innate Immunity

(2013) Sandra N. Lester et al.   JOURNAL OF MOLECULAR BIOLOGY

Dendritic Cell Immunoreceptor Regulates Chikungunya Virus Pathogenesis in Mice

(2013) K. M. Long et al.   JOURNAL OF VIROLOGY

Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

(2013) Caroline Goujon et al.   NATURE

MX2 is an interferon-induced inhibitor of HIV-1 infection

(2013) Melissa Kane et al.   NATURE

The C-type lectin receptor CLEC9A mediates antigen uptake and (cross-)presentation by human blood BDCA3+ myeloid dendritic cells

(2012) G. Schreibelt et al.   BLOOD

HCV glycoprotein E2 is a novel BDCA-2 ligand and acts as an inhibitor of IFN production by plasmacytoid dendritic cells

(2012) J. Florentin et al.   BLOOD

Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells

(2012) B. Chatterjee et al.   BLOOD

Increasing the efficacy of tumor cell vaccines by enhancing cross priming

(2012) Brian M. Andersen et al.   CANCER LETTERS

Intraendosomal flow cytometry: A novel approach to analyze the protein composition of antigen-loaded endosomes

(2012) Matthias Zehner et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice

(2012) Santiago Zelenay et al.   JOURNAL OF CLINICAL INVESTIGATION

The DC receptor DNGR-1 mediates cross-priming of CTLs during vaccinia virus infection in mice

(2012) Salvador Iborra et al.   JOURNAL OF CLINICAL INVESTIGATION

Glycan-modified liposomes boost CD4+ and CD8+ T-cell responses by targeting DC-SIGN on dendritic cells

(2012) Wendy W.J. Unger et al.   JOURNAL OF CONTROLLED RELEASE

Mosquito Bite Delivery of Dengue Virus Enhances Immunogenicity and Pathogenesis in Humanized Mice

(2012) J. Cox et al.   JOURNAL OF VIROLOGY

Regulation of antigen transport into the cytosol for cross-presentation by ubiquitination of the mannose receptor

(2012) Matthias Zehner et al.   MOLECULAR IMMUNOLOGY

Multivalent glycopeptide dendrimers for the targeted delivery of antigens to dendritic cells

(2012) Juan J. García-Vallejo et al.   MOLECULAR IMMUNOLOGY

Glycan-based DC-SIGN targeting vaccines to enhance antigen cross-presentation

(2012) Yvette van Kooyk et al.   MOLECULAR IMMUNOLOGY

Intrinsic antiviral immunity

(2012) Nan Yan et al.   NATURE IMMUNOLOGY

Siglec-1 Is a Novel Dendritic Cell Receptor That Mediates HIV-1 Trans-Infection Through Recognition of Viral Membrane Gangliosides

(2012) Nuria Izquierdo-Useros et al.   PLOS BIOLOGY

CLEC5A Regulates Japanese Encephalitis Virus-Induced Neuroinflammation and Lethality

(2012) Szu-Ting Chen et al.   PLoS Pathogens

DEC-205 mediates antigen uptake and presentation by both resting and activated human plasmacytoid dendritic cells

(2011) Jurjen Tel et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human Langerhans cells capture measles virus through Langerin and present viral antigens to CD4+ T cells but are incapable of cross-presentation

(2011) Michiel van der Vlist et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mannose receptor polyubiquitination regulates endosomal recruitment of p97 and cytosolic antigen translocation for cross-presentation

(2011) M. Zehner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pattern Recognition Receptors and the Innate Immune Response to Viral Infection

(2011) Mikayla R. Thompson et al.   Viruses-Basel

Cross-priming CD8+ T cells by targeting antigens to human dendritic cells through DCIR

(2010) E. Klechevsky et al.   BLOOD

The good and evil of complement activation in HIV-1 infection

(2010) Qigui Yu et al.   Cellular & Molecular Immunology

C-type lectin DC-SIGN: An adhesion, signalling and antigen-uptake molecule that guides dendritic cells in immunity

(2010) Urban Švajger et al.   CELLULAR SIGNALLING

Glycans as receptors for influenza pathogenesis

(2010) Karthik Viswanathan et al.   GLYCOCONJUGATE JOURNAL

Mechanisms by which HIV envelope minimizes immunogenicity

(2010) Haixiang Jiang et al.   IMMUNOLOGIC RESEARCH

Human CD141+(BDCA-3)+dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens

(2010) Sarah L. Jongbloed et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+cells as homologues of mouse CD8+dendritic cells

(2010) Annabell Bachem et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of human DNGR-1+BDCA3+leukocytes as putative equivalents of mouse CD8α+dendritic cells

(2010) Lionel Franz Poulin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Fundamental Difference in the Content of High-Mannose Carbohydrate in the HIV-1 and HIV-2 Lineages

(2010) E. Stansell et al.   JOURNAL OF VIROLOGY

HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells

(2010) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

HIV gp41 Engages gC1qR on CD4+ T Cells to Induce the Expression of an NK Ligand through the PIP3/H2O2 Pathway

(2010) Hugues Fausther-Bovendo et al.   PLoS Pathogens

HIV-1 Induces DCIR Expression in CD4+ T Cells

(2010) Alexandra A. Lambert et al.   PLoS Pathogens

Dusting the sugar fingerprint: C-type lectin signaling in adaptive immunity

(2009) Jeroen den Dunnen et al.   IMMUNOLOGY LETTERS

Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori

(2009) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

The IRF Family Transcription Factors in Immunity and Oncogenesis

(2008) Tomohiko Tamura et al.   Annual Review of Immunology

C-type lectins on dendritic cells: key modulators for the induction of immune responses

(2008) Yvette van Kooyk   BIOCHEMICAL SOCIETY TRANSACTIONS

Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses

(2008) C. Gurer et al.   BLOOD

The C-type lectin surface receptor DCIR acts as a new attachment factor for HIV-1 in dendritic cells and contributes to trans- and cis-infection pathways

(2008) A. A. Lambert et al.   BLOOD

Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-  production

(2008) F. Meyer-Wentrup et al.   BLOOD

DCIR is endocytosed into human dendritic cells and inhibits TLR8-mediated cytokine production

(2008) Friederike Meyer-Wentrup et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation

(2008) Sven Burgdorf et al.   NATURE IMMUNOLOGY

The Mannose Receptor Mediates Dengue Virus Infection of Macrophages

(2008) Joanna L. Miller et al.   PLoS Pathogens

IFN regulation and functions in myeloid dendritic cells

(2007) E COCCIA   CYTOKINE & GROWTH FACTOR REVIEWS