Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein
Authors
Keywords
-
Journal
Genome Medicine
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-07-29
DOI
10.1186/s13073-020-00763-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR
- (2020) Victor M Corman et al. Eurosurveillance
- An interactive web-based dashboard to track COVID-19 in real time
- (2020) Ensheng Dong et al. LANCET INFECTIOUS DISEASES
- A new coronavirus associated with human respiratory disease in China
- (2020) Fan Wu et al. NATURE
- A pneumonia outbreak associated with a new coronavirus of probable bat origin
- (2020) Peng Zhou et al. NATURE
- Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
- (2020) Daniel Wrapp et al. SCIENCE
- Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses
- (2020) Michael Letko et al. Nature Microbiology
- The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade
- (2020) B. Coutard et al. ANTIVIRAL RESEARCH
- The Architecture of SARS-CoV-2 Transcriptome
- (2020) Dongwan Kim et al. CELL
- Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
- (2020) Alexandra C. Walls et al. CELL
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- The proximal origin of SARS-CoV-2
- (2020) Kristian G. Andersen et al. NATURE MEDICINE
- SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology
- (2020) Natacha S. Ogando et al. JOURNAL OF GENERAL VIROLOGY
- Direct RNA sequencing on nanopore arrays redefines the transcriptional complexity of a viral pathogen
- (2019) Daniel P. Depledge et al. Nature Communications
- Direct RNA nanopore sequencing of full-length coronavirus genomes provides novel insights into structural variants and enables modification analysis
- (2019) Adrian Viehweger et al. GENOME RESEARCH
- Nanopore native RNA sequencing of a human poly(A) transcriptome
- (2019) Rachael E. Workman et al. NATURE METHODS
- High Resolution Analysis of Respiratory Syncytial Virus Infection In Vivo
- (2019) Waleed Aljabr et al. Viruses-Basel
- Human Coronavirus NL63 Molecular Epidemiology and Evolutionary Patterns in Rural Coastal Kenya
- (2018) Patience K Kiyuka et al. JOURNAL OF INFECTIOUS DISEASES
- Highly parallel direct RNA sequencing on an array of nanopores
- (2018) Daniel R Garalde et al. NATURE METHODS
- Pre-fusion structure of a human coronavirus spike protein
- (2016) Robert N. Kirchdoerfer et al. NATURE
- High-Resolution Analysis of Coronavirus Gene Expression by RNA Sequencing and Ribosome Profiling
- (2016) Nerea Irigoyen et al. PLoS Pathogens
- Structure, Function, and Evolution of Coronavirus Spike Proteins
- (2016) Fang Li Annual Review of Virology
- Host cell proteases: Critical determinants of coronavirus tropism and pathogenesis
- (2015) Jean Kaoru Millet et al. VIRUS RESEARCH
- Nucleocapsid Phosphorylation and RNA Helicase DDX1 Recruitment Enables Coronavirus Transition from Discontinuous to Continuous Transcription
- (2014) Chia-Hsin Wu et al. Cell Host & Microbe
- The Coronavirus Nucleocapsid Is a Multifunctional Protein
- (2014) Ruth McBride et al. Viruses-Basel
- Proteomics informed by transcriptomics reveals Hendra virus sensitizes bat cells to TRAIL mediated apoptosis
- (2014) James W Wynne et al. GENOME BIOLOGY
- Regulation of Coronaviral Poly(A) Tail Length during Infection
- (2013) Hung-Yi Wu et al. PLoS One
- De novo derivation of proteomes from transcriptomes for transcript and protein identification
- (2012) Vanessa C Evans et al. NATURE METHODS
- Cleavage and Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein by Human Airway Trypsin-Like Protease
- (2011) S. Bertram et al. JOURNAL OF VIROLOGY
- Elastase-mediated Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein at Discrete Sites within the S2 Domain
- (2010) Sandrine Belouzard et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterization of a Highly Conserved Domain within the Severe Acute Respiratory Syndrome Coronavirus Spike Protein S2 Domain with Characteristics of a Viral Fusion Peptide
- (2009) I. G. Madu et al. JOURNAL OF VIROLOGY
- Coronaviruses post-SARS: update on replication and pathogenesis
- (2009) Stanley Perlman et al. NATURE REVIEWS MICROBIOLOGY
- Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites
- (2009) S. Belouzard et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylation of the arginine/serine dipeptide-rich motif of the severe acute respiratory syndrome coronavirus nucleocapsid protein modulates its multimerization, translation inhibitory activity and cellular localization
- (2008) Tsui-Yi Peng et al. FEBS Journal
- Glycogen Synthase Kinase-3 Regulates the Phosphorylation of Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Protein and Viral Replication
- (2008) Chia-Hsin Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cathepsin L Functionally Cleaves the Severe Acute Respiratory Syndrome Coronavirus Class I Fusion Protein Upstream of Rather than Adjacent to the Fusion Peptide
- (2008) B. J. Bosch et al. JOURNAL OF VIROLOGY
- Role of phosphorylation clusters in the biology of the coronavirus infectious bronchitis virus nucleocapsid protein
- (2007) Kelly-Anne Spencer et al. VIROLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started