Dihydrotanshinone, a Natural Diterpenoid, Preserves Blood-Retinal Barrier Integrity via P2X7 Receptor
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Dihydrotanshinone, a Natural Diterpenoid, Preserves Blood-Retinal Barrier Integrity via P2X7 Receptor
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 23, Pages 9305
Publisher
MDPI AG
Online
2020-12-08
DOI
10.3390/ijms21239305
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A New Human Blood–Retinal Barrier Model Based on Endothelial Cells, Pericytes, and Astrocytes
- (2020) Claudia G. Fresta et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Dihydrotanshinone I Alleviates Spinal Cord Injury via Suppressing Inflammatory Response, Oxidative Stress and Apoptosis in Rats
- (2020) Liuqian Yu et al. MEDICAL SCIENCE MONITOR
- Novel indole derivatives targeting HuR-mRNA complex to counteract high glucose damage in retinal endothelial cells
- (2020) Chiara Bianca Maria Platania et al. BIOCHEMICAL PHARMACOLOGY
- Effects of protein-protein interface disruptors at the ligand of the glucocorticoid-induced tumor necrosis factor receptor-related gene (GITR)
- (2020) Chiara Bianca Maria Platania et al. BIOCHEMICAL PHARMACOLOGY
- P2X7 receptor antagonism preserves retinal ganglion cells in glaucomatous mice
- (2020) Giovanni Luca Romano et al. BIOCHEMICAL PHARMACOLOGY
- Microfluidics as a Novel Tool for Biological and Toxicological Assays in Drug Discovery Processes: Focus on Microchip Electrophoresis
- (2020) Giuseppe Caruso et al. Micromachines
- Highly‐expressed P2X7 receptor promotes growth and metastasis of human HOS/MNNG osteosarcoma cells via PI3K/Akt/GSK3β/β‐catenin and mTOR/HIF1α/VEGF signaling
- (2019) Yingchi Zhang et al. INTERNATIONAL JOURNAL OF CANCER
- Pharmacological blockade of the P2X7 receptor reverses retinal damage in a rat model of type 1 diabetes
- (2019) Carmen Clapp et al. ACTA DIABETOLOGICA
- Organ-On-A-Chip Technologies for Advanced Blood–Retinal Barrier Models
- (2019) Héloïse Ragelle et al. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
- Dihydrotanshinone exhibits an anti-inflammatory effect in vitro and in vivo through blocking TLR4 dimerization
- (2019) Renyikun Yuan et al. PHARMACOLOGICAL RESEARCH
- Fluoxetine and Vortioxetine Reverse Depressive-Like Phenotype and Memory Deficits Induced by Aβ1-42 Oligomers in Mice: A Key Role of Transforming Growth Factor-β1
- (2019) Sebastiano Alfio Torrisi et al. Frontiers in Pharmacology
- Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents
- (2019) Valeria Pittalà et al. Future Medicinal Chemistry
- Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology
- (2019) Olvera-Montaño Cecilia et al. Journal of Diabetes Research
- Blood-retinal barrier protection against high glucose damage: The role of P2X7 receptor
- (2019) Chiara Bianca Maria Platania et al. BIOCHEMICAL PHARMACOLOGY
- Full-Length P2X7 Structures Reveal How Palmitoylation Prevents Channel Desensitization
- (2019) Alanna E. McCarthy et al. CELL
- Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase
- (2019) Yasumitsu Sakamoto et al. Scientific Reports
- Carnosine Decreases PMA-Induced Oxidative Stress and Inflammation in Murine Macrophages
- (2019) Giuseppe Caruso et al. Antioxidants
- Discovery of Ganoderma lucidum triterpenoids as potential inhibitors against Dengue virus NS2B-NS3 protease
- (2019) Shiv Bharadwaj et al. Scientific Reports
- Diabetic retinopathy and endothelin system: microangiopathy versus endothelial dysfunction
- (2018) Francesco Saverio Sorrentino et al. EYE
- Recent Advances in CNS P2X7 Physiology and Pharmacology: Focus on Neuropsychiatric Disorders
- (2018) Anindya Bhattacharya Frontiers in Pharmacology
- Non-nucleotide Agonists Triggering P2X7 Receptor Activation and Pore Formation
- (2018) Francesco Di Virgilio et al. Frontiers in Pharmacology
- Importance of integrity of cell-cell junctions for the mechanics of confluent MDCK II cells
- (2018) Bastian Rouven Brückner et al. Scientific Reports
- Long-term efficacy and safety profile of multiple injections of intravitreal dexamethasone implant to manage diabetic macular edema: A systematic review of real-world studies
- (2018) Claudio Bucolo et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Hypoxic expression of NLRP3 and VEGF in cultured retinal pigment epithelial cells: contribution of P2Y2 receptor signaling
- (2018) Fabian Doktor et al. Purinergic Signalling
- Neuroinflammatory targets and treatments for epilepsy validated in experimental models
- (2017) Eleonora Aronica et al. EPILEPSIA
- Interplay between tight junctions & adherens junctions
- (2017) Hannah K. Campbell et al. EXPERIMENTAL CELL RESEARCH
- Ischemic Retinopathies: Oxidative Stress and Inflammation
- (2017) José Carlos Rivera et al. Oxidative Medicine and Cellular Longevity
- The inner blood-retinal barrier: Cellular basis and development
- (2017) Mónica Díaz-Coránguez et al. VISION RESEARCH
- Association between Aqueous Cytokines and Diabetic Retinopathy Stage
- (2017) Hailiang Wu et al. Journal of Ophthalmology
- The P2X7 Receptor-Interleukin-1 Liaison
- (2017) Anna Lisa Giuliani et al. Frontiers in Pharmacology
- Diabetic retinopathy: global prevalence, major risk factors, screening practices and public health challenges: a review
- (2016) Daniel Shu Wei Ting et al. CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- VIP Family Members Prevent Outer Blood Retinal Barrier Damage in a Model of Diabetic Macular Edema
- (2016) Grazia Maugeri et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Claudins in cancer: bench to bedside
- (2016) Makoto Osanai et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP
- (2016) Mausita Karmakar et al. Nature Communications
- Dipeptidyl Peptidase-4 Inhibitor Increases Vascular Leakage in Retina through VE-cadherin Phosphorylation
- (2016) Choon-Soo Lee et al. Scientific Reports
- P2X7 receptor activation regulates rapid unconventional export of transglutaminase-2
- (2015) M. Adamczyk et al. JOURNAL OF CELL SCIENCE
- Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function
- (2015) Vito Giuseppe D’Agostino et al. Scientific Reports
- Blockade of Vascular Endothelial Growth Factor Receptor 1 Prevents Inflammation and Vascular Leakage in Diabetic Retinopathy
- (2015) Jianbo He et al. Journal of Ophthalmology
- Hyperglycemia Induces Toll-Like Receptor-2 and -4 Expression and Activity in Human Microvascular Retinal Endothelial Cells: Implications for Diabetic Retinopathy
- (2015) Uthra Rajamani et al. Journal of Diabetes Research
- Purines in the eye: Recent evidence for the physiological and pathological role of purines in the RPE, retinal neurons, astrocytes, Müller cells, lens, trabecular meshwork, cornea and lacrimal gland
- (2014) Julie Sanderson et al. EXPERIMENTAL EYE RESEARCH
- Mechanosensitive release of adenosine 5′-triphosphate through pannexin channels and mechanosensitive upregulation of pannexin channels in optic nerve head astrocytes: A mechanism for purinergic involvement in chronic strain
- (2014) Jonathan M. Beckel et al. GLIA
- Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ-47965567
- (2013) Anindya Bhattacharya et al. BRITISH JOURNAL OF PHARMACOLOGY
- From Mechanosensitivity to Inflammatory Responses: New Players in the Pathology of Glaucoma
- (2013) David Križaj et al. CURRENT EYE RESEARCH
- VEGF but not PlGF disturbs the barrier of retinal endothelial cells
- (2013) Heidrun L. Deissler et al. EXPERIMENTAL EYE RESEARCH
- Purinergic regulation of high-glucose-induced caspase-1 activation in the rat retinal Müller cell line rMC-1
- (2011) Katherine E. Trueblood et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- A novel co-culture model of the blood-retinal barrier based on primary retinal endothelial cells, pericytes and astrocytes
- (2011) Joanna Wisniewska-Kruk et al. EXPERIMENTAL EYE RESEARCH
- A potential therapeutic role for P2X7 receptor (P2X7R) antagonists in the treatment of inflammatory diseases
- (2011) Nishkantha Arulkumaran et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Blood-Retinal Barrier
- (2010) José Cunha-Vaz et al. EUROPEAN JOURNAL OF OPHTHALMOLOGY
- Peroxynitrite Mediates Diabetes-Induced Endothelial Dysfunction: Possible Role of Rho Kinase Activation
- (2010) Azza B. El-Remessy et al. Experimental Diabetes Research
- Linking oxidative stress to inflammation: Toll-like receptors
- (2010) Roop Gill et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mammalian Mitochondrial Complex I: Biogenesis, Regulation, and Reactive Oxygen Species Generation
- (2009) Werner J.H. Koopman et al. ANTIOXIDANTS & REDOX SIGNALING
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now