Lactoferrin, a unique molecule with diverse therapeutical and nanotechnological applications

Lactoferrin’s Anti-Cancer Properties: Safety, Selectivity, and Wide Range of Action

(2020) Antimo Cutone et al.   Biomolecules

Sulfonate modified Lactoferrin nanoparticles as drug carriers with dual activity against HIV-1

(2020) Jagadeesh Senapathi et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Reprogramming Tumor Immune Microenvironment (TIME) and Metabolism via Biomimetic Targeting Codelivery of Shikonin/JQ1

(2019) Hairui Wang et al.   NANO LETTERS

On-Chip Preparation of Amphiphilic Nano-micelles-in-Sodium Alginate Spheroids (ANMs-in-SASs) as a Novel Platform Against Triple Negative Human Breast Cancer Cells: Fabrication, Study of Microfluidics Flow Hydrodynamics and Proof of Concept for Anticancer and Drug Delivery Applications

(2019) Doaa Ragab et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Starch-based nanocarriers as cutting-edge natural cargos for nutraceutical delivery

(2019) Hadis Rostamabadi et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Emerging Strategies in Stimuli-Responsive Nanocarriers as the Drug Delivery System for Enhanced Cancer Therapy

(2019) Kandasamy Saravanakumar et al.   CURRENT PHARMACEUTICAL DESIGN

Self-assembled amphiphilic zein-lactoferrin micelles for tumor targeted co-delivery of rapamycin and wogonin to breast cancer

(2018) Sally A. Sabra et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Receptor-mediated targeted delivery of DNA using Lactoferrin nanoparticles

(2018) Sonali Kumari et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Evaluation of Antiproliferative Activity, Safety and Biodistribution of Oxaliplatin and 5-Fluorouracil Loaded Lactoferrin Nanoparticles for the Management of Colon Adenocarcinoma: an In Vitro and an In Vivo Study

(2018) Farhan Ahmed et al.   PHARMACEUTICAL RESEARCH

Bovine Milk Lactoferrin Selectively Kills Highly Metastatic Prostate Cancer PC-3 and Osteosarcoma MG-63 Cells In Vitro

(2018) Joana P. Guedes et al.   Frontiers in Oncology

Antiglioma via regulating oxidative stress and remodeling tumor-associated macrophage using lactoferrin-mediated biomimetic codelivery of simvastatin/fenretinide

(2018) Xiaopeng Mo et al.   JOURNAL OF CONTROLLED RELEASE

Evaluation of the reproductive toxicity of antiretroviral drug loaded lactoferrin nanoparticles

(2018) Lavanya Madugulla et al.   Systems Biology in Reproductive Medicine

A Paradigm Shift in Cancer Immunotherapy: From Enhancement to Normalization

(2018) Miguel F. Sanmamed et al.   CELL

Magnetically Guided Self-Assembled Protein Micelles for Enhanced Delivery of Dasatinib to Human Triple-Negative Breast Cancer Cells

(2018) Sally A. Sabra et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Preservation of Cichoric Acid Antioxidant Properties Loaded in Heat Treated Lactoferrin Nanoparticles

(2018) Junyi Li et al.   MOLECULES

Aurora kinase B siRNA-loaded lactoferrin nanoparticles potentiate the efficacy of temozolomide in treating glioblastoma

(2018) Sonali Kumari et al.   Nanomedicine

Biocompatible Polyelectrolyte Complex Nanoparticles from Lactoferrin and Pectin as Potential Vehicles for Antioxidative Curcumin

(2017) Jing-Kun Yan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Preparation, characterization, and in vitro/vivo studies of oleanolic acid-loaded lactoferrin nanoparticles

(2017) Xiaojing Xia et al.   Drug Design Development and Therapy

Chlorin e6 loaded lactoferrin nanoparticles for enhanced photodynamic therapy

(2017) Mahesh G. Adimoolam et al.   Journal of Materials Chemistry B

Overcoming blood brain barrier with a dual purpose Temozolomide loaded Lactoferrin nanoparticles for combating glioma (SERP-17-12433)

(2017) Sonali Kumari et al.   Scientific Reports

Blood–Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglioma Therapy

(2016) Tingting Lin et al.   ACS Nano

Regulation of V-ATPase assembly and function of V-ATPases in tumor cell invasiveness

(2016) Christina McGuire et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Shikonin regulates C-MYC and GLUT1 expression through the MST1-YAP1-TEAD1 axis

(2016) Karel Vališ et al.   EXPERIMENTAL CELL RESEARCH

Lactoferrin-based nanoparticles as a vehicle for iron in food applications – Development and release profile

(2016) Joana T. Martins et al.   FOOD RESEARCH INTERNATIONAL

An oral formulation of efavirenz-loaded lactoferrin nanoparticles with improved biodistribution and pharmacokinetic profile

(2016) P Kumar et al.   HIV MEDICINE

Triple Drug Combination of Zidovudine, Efavirenz and Lamivudine Loaded Lactoferrin Nanoparticles: an Effective Nano First-Line Regimen for HIV Therapy

(2016) Prashant Kumar et al.   PHARMACEUTICAL RESEARCH

Triple combination MPT vaginal microbicide using curcumin and efavirenz loaded lactoferrin nanoparticles

(2016) Yeruva Samrajya Lakshmi et al.   Scientific Reports

BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression

(2016) Hengrui Zhu et al.   Cell Reports

Liposomal simvastatin inhibits tumor growth via targeting tumor-associated macrophages-mediated oxidative stress

(2015) Marius Costel Alupei et al.   CANCER LETTERS

In vitro and in vivo effect of human lactoferrin on glioblastoma growth

(2015) Antonietta Arcella et al.   JOURNAL OF NEUROSURGERY

Shikonin-enhanced cell immunogenicity of tumor vaccine is mediated by the differential effects of DAMP components

(2015) Tien-Jen Lin et al.   Molecular Cancer

Multifunctional Iron Bound Lactoferrin and Nanomedicinal Approaches to Enhance Its Bioactive Functions

(2015) Jagat Kanwar et al.   MOLECULES

Improved Safety, Bioavailability and Pharmacokinetics of Zidovudine through Lactoferrin Nanoparticles during Oral Administration in Rats

(2015) Prashant Kumar et al.   PLoS One

A lovastatin-elicited genetic program inhibits M2 macrophage polarization and enhances T cell infiltration into spontaneous mouse mammary tumors

(2015) Emilia Mira et al.   Oncotarget

Clerodendrum serratum (L.) Moon. – A review on traditional uses, phytochemistry and pharmacological activities

(2014) Jagruti J. Patel et al.   JOURNAL OF ETHNOPHARMACOLOGY

Lactoferrin-Modified Poly(ethylene glycol)-Grafted BSA Nanoparticles as a Dual-Targeting Carrier for Treating Brain Gliomas

(2014) Zhigui Su et al.   MOLECULAR PHARMACEUTICS

Colocalized Delivery of Rapamycin and Paclitaxel to Tumors Enhances Synergistic Targeting of the PI3K/Akt/mTOR Pathway

(2014) Elvin Blanco et al.   MOLECULAR THERAPY

Oleanane triterpenoids in the prevention and therapy of breast cancer: current evidence and future perspectives

(2014) Nisha R. Parikh et al.   PHYTOCHEMISTRY REVIEWS

Iron homeostasis and tumorigenesis: molecular mechanisms and therapeutic opportunities

(2014) Caiguo Zhang et al.   Protein & Cell

Studies on lactoferrin nanoparticles of gambogic acid for oral delivery

(2013) Zhen-Hai Zhang et al.   DRUG DELIVERY

Nanoencapsulation of bovine lactoferrin for food and biopharmaceutical applications

(2013) Victor M. Balcão et al.   FOOD HYDROCOLLOIDS

Bovine lactoferrin inhibits lung cancer growth through suppression of both inflammation and expression of vascular endothelial growth factor

(2013) Yu-Tang Tung et al.   JOURNAL OF DAIRY SCIENCE

Pharmacological Properties of Shikonin – A Review of Literature since 2002

(2013) Isabel Andújar et al.   PLANTA MEDICA

A Target-Specific Oral Formulation of Doxorubicin-Protein Nanoparticles: Efficacy and Safety in Hepatocellular Cancer

(2013) Kishore Golla et al.   Journal of Cancer

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

Surface-modified protein nanospheres as potential antiviral agents

(2012) Dana Baram-Pinto et al.   CHEMICAL COMMUNICATIONS

Micelle-like nanoassemblies based on polymer–drug conjugates as an emerging platform for drug delivery

(2012) Zhihong Liu et al.   Expert Opinion on Drug Delivery

Novel alginate-enclosed chitosan–calcium phosphate-loaded iron-saturated bovine lactoferrin nanocarriers for oral delivery in colon cancer therapy

(2012) Jagat R Kanwar et al.   Nanomedicine

Efficacy, Safety and Anticancer Activity of Protein Nanoparticle-Based Delivery of Doxorubicin through Intravenous Administration in Rats

(2012) Kishore Golla et al.   PLoS One

Formation of protein nanoparticles by controlled heat treatment of lactoferrin: Factors affecting particle characteristics

(2011) Carlos Bengoechea et al.   FOOD HYDROCOLLOIDS

CYP716A Subfamily Members are Multifunctional Oxidases in Triterpenoid Biosynthesis

(2011) Ery O. Fukushima et al.   PLANT AND CELL PHYSIOLOGY

Nanoparticle albumin-bound (nab™)-paclitaxel: improving efficacy and tolerability by targeted drug delivery in metastatic breast cancer

(2010) Javier Cortes et al.   EJC SUPPLEMENTS

PLAB induction in fenretinide-induced apoptosis of ovarian cancer cells occurs via a ROS-dependent mechanism involving ER stress and JNK activation

(2009) V. Appierto et al.   CARCINOGENESIS

Nanoparticle Albumin - Bound (NAB) Technology is a Promising Method for Anti-Cancer Drug Delivery

(2009) Qiang Fu et al.   Recent Patents on Anti-Cancer Drug Discovery

Lactoferrin: structure, function and applications

(2008) Susana A. González-Chávez et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

New Aspects of Nanopharmaceutical Delivery Systems

(2008) Priscyla D. Marcato et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY