Aurora kinase B siRNA-loaded lactoferrin nanoparticles potentiate the efficacy of temozolomide in treating glioblastoma

Receptor-mediated targeted delivery of DNA using Lactoferrin nanoparticles

(2018) Sonali Kumari et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Lactoferrin nanoparticle mediated targeted delivery of 5-fluorouracil for enhanced therapeutic efficacy

(2017) Sonali Kumari et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Biodegradable brain-penetrating DNA nanocomplexes and their use to treat malignant brain tumors

(2017) Panagiotis Mastorakos et al.   JOURNAL OF CONTROLLED RELEASE

siRNA Delivery Strategies: A Comprehensive Review of Recent Developments

(2017) Katyayani Tatiparti et al.   Nanomaterials

Overcoming blood brain barrier with a dual purpose Temozolomide loaded Lactoferrin nanoparticles for combating glioma (SERP-17-12433)

(2017) Sonali Kumari et al.   Scientific Reports

A designed recombinant fusion protein for targeted delivery of siRNA to the mouse brain

(2016) Mohamed Mohamed Haroon et al.   JOURNAL OF CONTROLLED RELEASE

Neuroprotective effect of curcumin-loaded lactoferrin nano particles against rotenone induced neurotoxicity

(2016) V. Satish Bollimpelli et al.   NEUROCHEMISTRY INTERNATIONAL

Triple combination MPT vaginal microbicide using curcumin and efavirenz loaded lactoferrin nanoparticles

(2016) Yeruva Samrajya Lakshmi et al.   Scientific Reports

Encapsulation of temozolomide in a tumor-targeting nanocomplex enhances anti-cancer efficacy and reduces toxicity in a mouse model of glioblastoma

(2015) Sang-Soo Kim et al.   CANCER LETTERS

Hepatocyte-Specific Delivery of siRNAs Conjugated to Novel Non-nucleosidic TrivalentN-Acetylgalactosamine Elicits Robust Gene Silencing in Vivo

(2015) Kallanthottathil G. Rajeev et al.   CHEMBIOCHEM

Systemic Delivery of Stable siRNA-Encapsulating Lipid Vesicles: Optimization, Biodistribution, and Tumor Suppression

(2015) Ghulam Hassan Dar et al.   MOLECULAR PHARMACEUTICS

Knocking down disease: a progress report on siRNA therapeutics

(2015) Anders Wittrup et al.   NATURE REVIEWS GENETICS

Macrophage Ablation Reduces M2-Like Populations and Jeopardizes Tumor Growth in a MAFIA-Based Glioma Model

(2015) Konrad Gabrusiewicz et al.   NEOPLASIA

Advances in systemic siRNA delivery

(2015) Q. Leng et al.   DRUGS OF THE FUTURE

Improved Safety, Bioavailability and Pharmacokinetics of Zidovudine through Lactoferrin Nanoparticles during Oral Administration in Rats

(2015) Prashant Kumar et al.   PLoS One

A Nanoparticle Carrying the p53 Gene Targets Tumors Including Cancer Stem Cells, Sensitizes Glioblastoma to Chemotherapy and Improves Survival

(2014) Sang-Soo Kim et al.   ACS Nano

Anti glioma effect of doxorubicin loaded liposomes modified with angiopep-2

(2014) Mei Danyu   African Journal of Pharmacy and Pharmacology

Tumor-targeting dual peptides-modified cationic liposomes for delivery of siRNA and docetaxel to gliomas

(2014) Zhen-Zhen Yang et al.   BIOMATERIALS

Multivalent N-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing

(2014) Jayaprakash K. Nair et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lactoferrin-Modified Poly(ethylene glycol)-Grafted BSA Nanoparticles as a Dual-Targeting Carrier for Treating Brain Gliomas

(2014) Zhigui Su et al.   MOLECULAR PHARMACEUTICS

Magnetic Core-Shell Nanocapsules with Dual-Targeting Capabilities and Co-Delivery of Multiple Drugs to Treat Brain Gliomas

(2014) Jen-Hung Fang et al.   Advanced Healthcare Materials

Layer-by-Layer Nanoparticles for Systemic Codelivery of an Anticancer Drug and siRNA for Potential Triple-Negative Breast Cancer Treatment

(2013) Zhou J. Deng et al.   ACS Nano

Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics

(2013) Martin A Maier et al.   MOLECULAR THERAPY

Early Assessment of the Efficacy of Temozolomide Chemotherapy in Experimental Glioblastoma Using [18F]FLT-PET Imaging

(2013) Thomas Viel et al.   PLoS One

Targeted Delivery of siRNA-Generating DNA Nanocassettes Using Multifunctional Nanoparticles

(2013) Young-Seok Cho et al.   Small

Small interfering RNA-based molecular therapy of cancers

(2013) Wei Guo et al.   Chinese Journal of Cancer

The six amino acid antimicrobial peptide bLFcin6penetrates cells and delivers siRNA

(2012) Bing Fang et al.   FEBS Journal

Smart multifunctional core–shell nanospheres with drug and gene co-loaded for enhancing the therapeutic effect in a rat intracranial tumor model

(2012) HanJie Wang et al.   Nanoscale

Efficacy, Safety and Anticancer Activity of Protein Nanoparticle-Based Delivery of Doxorubicin through Intravenous Administration in Rats

(2012) Kishore Golla et al.   PLoS One

Aurora B kinase phosphorylates and instigates degradation of p53

(2012) C. P. Gully et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Current Review of in Vivo GBM Rodent Models: Emphasis on the CNS-1 Tumour Model

(2011) Valerie L. Jacobs et al.   ASN Neuro

Focused ultrasound disruption of the blood-brain barrier: a new frontier for therapeutic delivery in molecular neurooncology

(2011) Arnold B. Etame et al.   Neurosurgical Focus

Temozolomide: Mechanisms of Action, Repair and Resistance

(2011) Jihong Zhang et al.   Current Molecular Pharmacology

Molecular diagnostics of gliomas: state of the art

(2010) Markus J. Riemenschneider et al.   ACTA NEUROPATHOLOGICA

Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles

(2010) Chunbai He et al.   BIOMATERIALS

Experimental immunotherapy for malignant glioma: lessons from two decades of research in the GL261 model

(2010) Wim Maes et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Temozolomide: therapeutic limitations in the treatment of adult high-grade gliomas

(2010) Marc C Chamberlain   Expert Review of Neurotherapeutics

Systemic delivery of neutralizing antibody targeting CCL2 for glioma therapy

(2010) Xinmei Zhu et al.   JOURNAL OF NEURO-ONCOLOGY

Extended-schedule dose-dense temozolomide in refractory gliomas

(2009) A. Berrocal et al.   JOURNAL OF NEURO-ONCOLOGY

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

An Efficient Targeted Drug Delivery through Apotransferrin Loaded Nanoparticles

(2009) Athuluri Divakar Sai Krishna et al.   PLoS One

In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(–PEG)/siRNA complexes

(2009) Anastasia Malek et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effect of trastuzumab-modified antisense oligonucleotide-loaded human serum albumin nanoparticles prepared by heat denaturation

(2008) Isabel M. Steinhauser et al.   BIOMATERIALS

An endosomolytic Tat peptide produced by incorporation of histidine and cysteine residues as a nonviral vector for DNA transfection

(2008) Seong Loong Lo et al.   BIOMATERIALS

Engineering and expression of a chimeric transferrin receptor monoclonal antibody for blood-brain barrier delivery in the mouse

(2008) Ruben J. Boado et al.   BIOTECHNOLOGY AND BIOENGINEERING

Temozolomide Preferentially Depletes Cancer Stem Cells in Glioblastoma

(2008) D. Beier et al.   CANCER RESEARCH

DNA repair and cancer stem-like cells – Potential partners in glioma drug resistance?

(2008) Tor-Christian Aase Johannessen et al.   CANCER TREATMENT REVIEWS

Recent Approaches to Improve the Antitumor Efficacy of Temozolomide

(2008) Lucio Tentori et al.   CURRENT MEDICINAL CHEMISTRY

Pharmacokinetics and Biodistribution of Nanoparticles

(2008) Shyh-Dar Li et al.   MOLECULAR PHARMACEUTICS

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

(2008) Akin Akinc et al.   NATURE BIOTECHNOLOGY

Chemical Modification of siRNAs for In Vivo Use

(2008) Mark A. Behlke   OLIGONUCLEOTIDES

The use of lactoferrin as a ligand for targeting the polyamidoamine-based gene delivery system to the brain

(2007) Rongqin Huang et al.   BIOMATERIALS

Solid lipid nanoparticles of temozolomide: Potential reduction of cardial and nephric toxicity

(2007) Guihua Huang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS