Iron homeostasis and tumorigenesis: molecular mechanisms and therapeutic opportunities
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Title
Iron homeostasis and tumorigenesis: molecular mechanisms and therapeutic opportunities
Authors
Keywords
Iron tumorigenesis, p53, Wnt, DNA repair, cell cycle
Journal
Protein & Cell
Volume 6, Issue 2, Pages 88-100
Publisher
Springer Nature
Online
2014-12-05
DOI
10.1007/s13238-014-0119-z
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Note: Only part of the references are listed.- Proteomic study reveals a functional network of cancer markers in the G1-Stage of the breast cancer cell cycle
- (2014) Milagros J Tenga et al. BMC CANCER
- Iron oxide nanoparticles mediated cytotoxicity via PI3K/AKT pathway: Role of quercetin
- (2014) Abhijit Sarkar et al. FOOD AND CHEMICAL TOXICOLOGY
- Regulatory effect of iron regulatory protein-2 on iron metabolism in lung cancer
- (2014) Z. Cheng et al. GENETICS AND MOLECULAR RESEARCH
- A review of metal-catalyzed molecular damage: protection by melatonin
- (2014) Alejandro Romero et al. JOURNAL OF PINEAL RESEARCH
- Regulation of cellular iron metabolism and its implications in lung cancer progression
- (2014) Wei Xiong et al. MEDICAL ONCOLOGY
- Systemic and tumor level iron regulation in men with colorectal cancer: a case control study
- (2014) Cenk K Pusatcioglu et al. Nutrition & Metabolism
- Myeloid zinc-finger 1 (MZF-1) suppresses prostate tumor growth through enforcing ferroportin-conducted iron egress
- (2014) Y Chen et al. ONCOGENE
- Ribonucleotide reductase and cancer: biological mechanisms and targeted therapies
- (2014) Y Aye et al. ONCOGENE
- Perioperative anemia management in colorectal cancer patients: A pragmatic approach
- (2014) Manuel Muñoz WORLD JOURNAL OF GASTROENTEROLOGY
- Cyclin D1 gene amplification is highly homogeneous in breast cancer
- (2014) Eike Burandt et al. Breast Cancer
- Iron Metabolism Regulates p53 Signaling through Direct Heme-p53 Interaction and Modulation of p53 Localization, Stability, and Function
- (2014) Jia Shen et al. Cell Reports
- Essential functions of iron-requiring proteins in DNA replication, repair and cell cycle control
- (2014) Caiguo Zhang Protein & Cell
- Role of AMP-Activated Protein Kinase in Ferritin H Gene Expression by Resveratrol in Human T Cells
- (2013) Kenta Iwasaki et al. BIOCHEMISTRY
- Hypoxia upregulates the gene expression of mitochondrial aconitase in prostate carcinoma cells
- (2013) Ke-Hung Tsui et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Therapeutic efficacy of intravenously administered transferrin-conjugated dendriplexes on prostate carcinomas
- (2013) Majed Al Robaian et al. Nanomedicine
- Inhibition of β2-Microglobulin/Hemochromatosis Enhances Radiation Sensitivity by Induction of Iron Overload in Prostate Cancer Cells
- (2013) Sajni Josson et al. PLoS One
- Intestinal Iron Homeostasis and Colon Tumorigenesis
- (2013) Xiang Xue et al. Nutrients
- Iron Deficiency Anemia: A Common and Curable Disease
- (2013) J. L. Miller Cold Spring Harbor Perspectives in Medicine
- Pharmacological ascorbate and ionizing radiation (IR) increase labile iron in pancreatic cancer
- (2013) Justin C. Moser et al. Redox Biology
- Mechanisms of Mammalian Iron Homeostasis
- (2012) Kostas Pantopoulos et al. BIOCHEMISTRY
- The role of mitochondria in cellular iron–sulfur protein biogenesis and iron metabolism
- (2012) Roland Lill et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Lipocalin 2 expression is associated with aggressive features of endometrial cancer
- (2012) Monica Mannelqvist et al. BMC CANCER
- Nitrosamines and Heme Iron and Risk of Prostate Cancer in the European Prospective Investigation into Cancer and Nutrition
- (2012) P. G. Jakszyn et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Hypoxia-Inducible Factor-2 Activation Promotes Colorectal Cancer Progression by Dysregulating Iron Homeostasis
- (2012) X. Xue et al. CANCER RESEARCH
- Erythropoietin, ferritin, haptoglobin, hemoglobin and transferrin receptor in metabolic syndrome: a case control study
- (2012) Päivi Hämäläinen et al. Cardiovascular Diabetology
- Lipocalin 2 is a novel regulator of angiogenesis in human breast cancer
- (2012) Jiang Yang et al. FASEB JOURNAL
- Estrogen regulates iron homeostasis through governing hepatic hepcidin expression via an estrogen response element
- (2012) Yanli Hou et al. GENE
- Metalloreductase Steap3 coordinates the regulation of iron homeostasis and inflammatory responses
- (2012) F. Zhang et al. HAEMATOLOGICA
- Dietary intake of iron, heme-iron and magnesium and pancreatic cancer risk in the European prospective investigation into cancer and nutrition cohort
- (2012) Esther Molina-Montes et al. INTERNATIONAL JOURNAL OF CANCER
- DNA helicase and helicase-nuclease enzymes with a conserved iron-sulfur cluster
- (2012) Y. Wu et al. NUCLEIC ACIDS RESEARCH
- Lipocalin2 Promotes Invasion, Tumorigenicity and Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma
- (2012) Lisa Leung et al. PLoS One
- Wnt signaling in myogenesis
- (2012) Julia von Maltzahn et al. TRENDS IN CELL BIOLOGY
- Ferritin as an independent mortality predictor in patients with pancreas cancer. Results of a pilot study
- (2012) Marta Kalousová et al. TUMOR BIOLOGY
- Luminal Iron Levels Govern Intestinal Tumorigenesis after Apc Loss In Vivo
- (2012) Sorina Radulescu et al. Cell Reports
- Inhibition of tumor growth by recombinant adenovirus containing human lactoferrin through inducing tumor cell apoptosis in mice bearing EMT6 breast cancer
- (2011) Jianjie Wang et al. ARCHIVES OF PHARMACAL RESEARCH
- The transferrin receptor and the targeted delivery of therapeutic agents against cancer
- (2011) Tracy R. Daniels et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Regulation of iron transport and the role of transferrin
- (2011) Konstantinos Gkouvatsos et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Wnt Inhibitor Screen Reveals Iron Dependence of -Catenin Signaling in Cancers
- (2011) S. Song et al. CANCER RESEARCH
- Interaction of Triapine and related thiosemicarbazones with iron(iii)/(ii) and gallium(iii): a comparative solution equilibrium study
- (2011) Éva A. Enyedy et al. DALTON TRANSACTIONS
- Could exhaled ferritin and SOD be used as markers for lung cancer and prognosis prediction purposes?
- (2011) Giovanna E. Carpagnano et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Nrf2-dependent induction of NQO1 in mouse aortic endothelial cells overexpressing catalase
- (2011) Xinghua Lin et al. FREE RADICAL BIOLOGY AND MEDICINE
- Obesity and pancreatic cancer: Overview of epidemiologic evidence and biologic mechanisms
- (2011) Paige M. Bracci MOLECULAR CARCINOGENESIS
- The Major Roles of DNA Polymerases Epsilon and Delta at the Eukaryotic Replication Fork Are Evolutionarily Conserved
- (2011) Izumi Miyabe et al. PLoS Genetics
- In anemia of multiple myeloma, hepcidin is induced by increased bone morphogenetic protein 2
- (2010) K. Maes et al. BLOOD
- Role of ferritin alterations in human breast cancer cells
- (2010) Svitlana I. Shpyleva et al. BREAST CANCER RESEARCH AND TREATMENT
- Development of Human Single-Chain Antibodies to the Transferrin Receptor that Effectively Antagonize the Growth of Leukemias and Lymphomas
- (2010) R. Crepin et al. CANCER RESEARCH
- Iron overload in hematologic malignancies and outcome of allogeneic hematopoietic stem cell transplantation
- (2010) J. Koreth et al. HAEMATOLOGICA
- ZRT/IRT-like Protein 14 (ZIP14) Promotes the Cellular Assimilation of Iron from Transferrin
- (2010) Ningning Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Relationships of lipocalin 2 with breast tumorigenesis and metastasis
- (2010) Xiaohong Leng et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Anemia in Hodgkin's Lymphoma: The Role of Interleukin-6 and Hepcidin
- (2010) Stefan Hohaus et al. JOURNAL OF CLINICAL ONCOLOGY
- The effect of bovine milk lactoferrin on human breast cancer cell lines
- (2010) D.C. Duarte et al. JOURNAL OF DAIRY SCIENCE
- Mouse models for unraveling the importance of diet in colon cancer prevention
- (2010) Alexandra E. Tammariello et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Highly mutagenic and severely imbalanced dNTP pools can escape detection by the S-phase checkpoint
- (2010) Dinesh Kumar et al. NUCLEIC ACIDS RESEARCH
- Disruption of the Lcn2 gene in mice suppresses primary mammary tumor formation but does not decrease lung metastasis
- (2010) T. Berger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DNA replication fidelity and cancer
- (2010) Bradley D. Preston et al. SEMINARS IN CANCER BIOLOGY
- Cell Death Mechanisms and Their Implications in Toxicology
- (2010) Sten Orrenius et al. TOXICOLOGICAL SCIENCES
- Iron-Dependent Regulation of MDM2 Influences p53 Activity and Hepatic Carcinogenesis
- (2009) Paola Dongiovanni et al. AMERICAN JOURNAL OF PATHOLOGY
- Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells
- (2009) Y. Eberhard et al. BLOOD
- Inhibition of Lipocalin 2 Impairs Breast Tumorigenesis and Metastasis
- (2009) X. Leng et al. CANCER RESEARCH
- Mammalian iron transport
- (2009) Gregory Jon Anderson et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Iron Acquisition and Transcriptional Regulation
- (2009) Craig D. Kaplan et al. CHEMICAL REVIEWS
- Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
- (2009) Bryan T. MacDonald et al. DEVELOPMENTAL CELL
- Modulation of Iron-Regulatory Genes in Human Hepatocellular Carcinoma and Its Physiological Consequences
- (2009) Michelle Guet Khim Tan et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- HFE C282Y homozygotes are at increased risk of breast and colorectal cancer
- (2009) Nicholas J. Osborne et al. HEPATOLOGY
- Lipocalin 2 Expressions Correlate Significantly With Tumor Differentiation in Epithelial Ovarian Cancer
- (2009) HanByoul Cho et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- 2-Acetylpyridine Thiosemicarbazones are Potent Iron Chelators and Antiproliferative Agents: Redox Activity, Iron Complexation and Characterization of their Antitumor Activity
- (2009) Des R. Richardson et al. JOURNAL OF MEDICINAL CHEMISTRY
- Altered iron metabolism, inflammation, transferrin receptors, and ferritin expression in non-small-cell lung cancer
- (2009) Suzana Kukulj et al. MEDICAL ONCOLOGY
- Iron-saturated lactoferrin stimulates cell cycle progression through PI3K/Akt pathway
- (2009) Shin-Hee Lee et al. MOLECULES AND CELLS
- Lipocalin 2 promotes breast cancer progression
- (2009) J. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hydroxyl radical is produced via the Fenton reaction in submitochondrial particles under oxidative stress: implications for diseases associated with iron accumulation
- (2009) Carin Thomas et al. REDOX REPORT
- Systemic Iron Homeostasis and the Iron-Responsive Element/Iron-Regulatory Protein (IRE/IRP) Regulatory Network
- (2008) Martina U. Muckenthaler et al. Annual Review of Nutrition
- Intracellular Iron Transport and Storage: From Molecular Mechanisms to Health Implications
- (2008) Elizabeth L. Mackenzie et al. ANTIOXIDANTS & REDOX SIGNALING
- Redox Regulation of Cell Survival
- (2008) Dunyaporn Trachootham et al. ANTIOXIDANTS & REDOX SIGNALING
- Cancer related inflammation: The macrophage connection
- (2008) Antonio Sica et al. CANCER LETTERS
- Post-transcriptional Modulation of Iron Homeostasis during p53-dependent Growth Arrest
- (2008) Fan Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cancer-related inflammation
- (2008) Alberto Mantovani et al. NATURE
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