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Title
Unique signatures of stress-induced senescent human astrocytes
Authors
Keywords
Senescence, Reactive astrocyte, Rotenone, Parkinson's disease, iPSC derived neurons, Astrocyte neuron interplay, Alpha synuclein
Journal
EXPERIMENTAL NEUROLOGY
Volume 334, Issue -, Pages 113466
Publisher
Elsevier BV
Online
2020-09-17
DOI
10.1016/j.expneurol.2020.113466
References
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Note: Only part of the references are listed.- Modeling Cell-Cell Interactions in Parkinson’s Disease Using Human Stem Cell-Based Models
- (2020) Katrin Simmnacher et al. Frontiers in Cellular Neuroscience
- Demonstration of brain region-specific neuronal vulnerability in human iPSC-based model of familial Parkinson’s disease
- (2020) Razvan-Marius Brazdis et al. HUMAN MOLECULAR GENETICS
- Patient-Specific iPSC-Derived Astrocytes Contribute to Non-Cell-Autonomous Neurodegeneration in Parkinson's Disease
- (2019) Angelique di Domenico et al. Stem Cell Reports
- Parkinson's Disease and the Environment
- (2019) Nicole Ball et al. Frontiers in Neurology
- Oxidative stress in the aging substantia nigra and the etiology of Parkinson's disease
- (2019) Benjamin G. Trist et al. AGING CELL
- The interplay of aging, genetics and environmental factors in the pathogenesis of Parkinson’s disease
- (2019) Shirley Yin-Yu Pang et al. Translational Neurodegeneration
- Effect of Dickkopf1 on the senescence of melanocytes: in vitro study
- (2018) Seema Rani et al. ARCHIVES OF DERMATOLOGICAL RESEARCH
- Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson’s Disease
- (2018) Annika Sommer et al. Cell Stem Cell
- Early activation of Egr-1 promotes neuroinflammation and dopaminergic neurodegeneration in an experimental model of Parkinson's disease
- (2018) Qing Yu et al. EXPERIMENTAL NEUROLOGY
- Is DNA damage indispensable for stress-induced senescence?
- (2018) Anna Bielak-Zmijewska et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Senolytics improve physical function and increase lifespan in old age
- (2018) Ming Xu et al. NATURE MEDICINE
- α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies
- (2018) Iryna Prots et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Normal aging induces A1-like astrocyte reactivity
- (2018) Laura E. Clarke et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cellular Senescence Is Induced by the Environmental Neurotoxin Paraquat and Contributes to Neuropathology Linked to Parkinson’s Disease
- (2018) Shankar J. Chinta et al. Cell Reports
- The Aging Astrocyte Transcriptome from Multiple Regions of the Mouse Brain
- (2018) Matthew M. Boisvert et al. Cell Reports
- Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline
- (2018) Tyler J. Bussian et al. NATURE
- T-type Calcium Channels Determine the Vulnerability of Dopaminergic Neurons to Mitochondrial Stress in Familial Parkinson Disease
- (2018) Yoshikuni Tabata et al. Stem Cell Reports
- Neurotoxic reactive astrocytes are induced by activated microglia
- (2017) Shane A. Liddelow et al. NATURE
- β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson’s disease
- (2017) Shuchi Mittal et al. SCIENCE
- Astrocyte Senescence and Metabolic Changes in Response to HIV Antiretroviral Therapy Drugs
- (2017) Justin Cohen et al. Frontiers in Aging Neuroscience
- An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells
- (2017) Julia TCW et al. Stem Cell Reports
- Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells
- (2017) Renata Santos et al. Stem Cell Reports
- Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link?
- (2017) Viktor I. Korolchuk et al. EBioMedicine
- Transcriptome Analysis Reveals Neuroprotective aspects of Human Reactive Astrocytes induced by Interleukin 1β
- (2017) Daniel Boon Loong Teh et al. Scientific Reports
- Biomarkers to identify and isolate senescent cells
- (2016) Mantas Matjusaitis et al. AGEING RESEARCH REVIEWS
- Keeping the senescence secretome under control: Molecular reins on the senescence-associated secretory phenotype
- (2016) Nicolas Malaquin et al. EXPERIMENTAL GERONTOLOGY
- Adaptive regulation of the brain’s antioxidant defences by neurons and astrocytes
- (2016) Paul S. Baxter et al. FREE RADICAL BIOLOGY AND MEDICINE
- The cell fate: senescence or quiescence
- (2016) Menderes Yusuf Terzi et al. MOLECULAR BIOLOGY REPORTS
- Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
- (2016) Darren J. Baker et al. NATURE
- mTOR Signaling in Parkinson’s Disease
- (2016) Ai-ping Lan et al. NEUROMOLECULAR MEDICINE
- Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse
- (2016) Ye Zhang et al. NEURON
- Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses
- (2016) Katannya Kapeli et al. Nature Communications
- Mitochondrial Complex 1 Activity Measured by Spectrophotometry Is Reduced across All Brain Regions in Ageing and More Specifically in Neurodegeneration
- (2016) Amelia Kate Pollard et al. PLoS One
- Blockade of metabotropic glutamate receptor 5 protects against DNA damage in a rotenone-induced Parkinson's disease model
- (2015) Ning Xia et al. FREE RADICAL BIOLOGY AND MEDICINE
- Striatal Blood–Brain Barrier Permeability in Parkinson'S Disease
- (2015) Madison T Gray et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Astrocyte-conditioned medium attenuates glutamate-induced apoptotic cell death in primary cultured spinal cord neurons of rats
- (2015) Xiaojian Lu et al. NEUROLOGICAL RESEARCH
- Oxidative stress and Parkinson’s disease
- (2015) Javier Blesa et al. Frontiers in Neuroanatomy
- Sensitive western blotting for detection of endogenous Ser129-phosphorylated α-synuclein in intracellular and extracellular spaces
- (2015) Asuka Sasaki et al. Scientific Reports
- NF-kappaB Signaling Pathways in Neurological Inflammation: A Mini Review
- (2015) Ruey-Horng Shih et al. Frontiers in Molecular Neuroscience
- CLCA2 as a p53-Inducible Senescence Mediator
- (2015) Chizu Tanikawa et al. NEOPLASIA
- Dickkopf-1, the Wnt antagonist, is induced by acidic pH and mediates epithelial cellular senescence in human reflux esophagitis
- (2014) Orestis Lyros et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Cholesterol Homeostasis Failure in the Brain: Implications for Synaptic Dysfunction and Cognitive Decline
- (2014) Marco Segatto et al. CURRENT MEDICINAL CHEMISTRY
- LPS and IL-1 differentially activate mouse and human astrocytes: Role of CD14
- (2014) Leonid Tarassishin et al. GLIA
- Matricellular protein CCN1/CYR61: a new player in inflammation and leukocyte trafficking
- (2014) Yalin Emre et al. Seminars in Immunopathology
- The degeneration and replacement of dopamine cells in Parkinson’s disease: the role of aging
- (2014) Manuel Rodriguez et al. Frontiers in Neuroanatomy
- Astrocyte-Secreted Matricellular Proteins in CNS Remodelling during Development and Disease
- (2014) Emma V. Jones et al. NEURAL PLASTICITY
- MMP-3 Contributes to Nigrostriatal Dopaminergic Neuronal Loss, BBB Damage, and Neuroinflammation in an MPTP Mouse Model of Parkinson’s Disease
- (2013) Young Cheul Chung et al. MEDIATORS OF INFLAMMATION
- A complex secretory program orchestrated by the inflammasome controls paracrine senescence
- (2013) Juan Carlos Acosta et al. NATURE CELL BIOLOGY
- Isradipine prevents rotenone-induced intracellular calcium rise that accelerates senescence in human neuroblastoma SH-SY5Y cells
- (2013) X. Yu et al. NEUROSCIENCE
- Human Stem Cell-Derived Spinal Cord Astrocytes with Defined Mature or Reactive Phenotypes
- (2013) Laurent Roybon et al. Cell Reports
- A phenotypic model recapitulating the neuropathology of Parkinson's disease
- (2013) Craig F. Ferris et al. Brain and Behavior
- Rotenone Inhibits Autophagic Flux Prior to Inducing Cell Death
- (2012) Burton J. Mader et al. ACS Chemical Neuroscience
- Rotenone-induced apoptosis and role of calcium: a study on Neuro-2a cells
- (2012) Supriya Swarnkar et al. ARCHIVES OF TOXICOLOGY
- Astrocyte mediated protection of fetal cerebral cortical neurons from rotenone and paraquat
- (2012) Mary Latha Rathinam et al. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
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- (2012) Judith-Irina Pagel et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- DJ-1 Protects Dopaminergic Neurons against Rotenone-Induced Apoptosis by Enhancing ERK-Dependent Mitophagy
- (2012) H. Gao et al. JOURNAL OF MOLECULAR BIOLOGY
- Increased blood-cerebrospinal fluid transfer of albumin in advanced Parkinson’s disease
- (2012) Valerio Pisani et al. Journal of Neuroinflammation
- NP1 Regulates Neuronal Activity-Dependent Accumulation of BAX in Mitochondria and Mitochondrial Dynamics
- (2012) K. B. Clayton et al. JOURNAL OF NEUROSCIENCE
- The Secreted Wnt Antagonist Dickkopf-1 Is Required for Amyloid -Mediated Synaptic Loss
- (2012) S. A. Purro et al. JOURNAL OF NEUROSCIENCE
- TNFα-Induced Apoptosis Enabled by CCN1/CYR61: Pathways of Reactive Oxygen Species Generation and Cytochrome c Release
- (2012) Vladislava Juric et al. PLoS One
- Astrocyte Senescence as a Component of Alzheimer’s Disease
- (2012) Rekha Bhat et al. PLoS One
- Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson's Disease
- (2012) O. Cooper et al. Science Translational Medicine
- Rotenone, Paraquat, and Parkinson’s Disease
- (2011) Caroline M. Tanner et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Egr-1 Transactivates Bim Gene Expression to Promote Neuronal Apoptosis
- (2011) B. Xie et al. JOURNAL OF NEUROSCIENCE
- Stress-induced senescence in human and rodent astrocytes
- (2010) Alessandro Bitto et al. EXPERIMENTAL CELL RESEARCH
- The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing
- (2010) Joon-Il Jun et al. NATURE CELL BIOLOGY
- A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen
- (2010) Jean-Philippe Coppé et al. PLoS One
- DNA damage response and cellular senescence in tissues of aging mice
- (2009) Chunfang Wang et al. AGING CELL
- Rapid flow cytometric method for measuring senescence associated β-galactosidase activity in human fibroblasts
- (2009) Gerard Noppe et al. CYTOMETRY PART A
- Fas-Mediated Apoptosis Is Regulated by the Extracellular Matrix Protein CCN1 (CYR61) In Vitro and In Vivo
- (2009) V. Juric et al. MOLECULAR AND CELLULAR BIOLOGY
- A highly reproducible rotenone model of Parkinson's disease
- (2009) Jason R. Cannon et al. NEUROBIOLOGY OF DISEASE
- Cell-specific and concentration-dependent actions of interleukin-1 in acute brain inflammation
- (2008) Emmanuel Pinteaux et al. CYTOKINE
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