The cell fate: senescence or quiescence

Markers of cellular senescence. Telomere shortening as a marker of cellular senescence

(2016) Alexandra Bernadotte et al.   Aging-US

DNA damaging agents and p53 do not cause senescence in quiescent cells, while consecutive re-activation of mTOR is associated with conversion to senescence

(2016) Olga V. Leontieva et al.   Aging-US

mTOR favors senescence over quiescence in p53-arrested cells

(2016) Thaddeus T. Schug   Aging-US

The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway

(2016) Lioubov G. Korotchkina et al.   Aging-US

Be quiet and you'll keep young: does mTOR underlie p53 action in protecting against senescence by favoring quiescence?

(2016) Vjekoslav Dulic   Aging-US

Cell cycle arrest is not senescence

(2016) Mikhail V. Blagosklonny   Aging-US

Senescence as a general cellular response to stress: A mini-review

(2015) Irina Fridlyanskaya et al.   EXPERIMENTAL GERONTOLOGY

ATM in senescence

(2015) Katherine M. Aird et al.   Oncotarget

MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition

(2015) Marta Kovatcheva et al.   Oncotarget

ATM Couples Replication Stress and Metabolic Reprogramming during Cellular Senescence

(2015) Katherine M. Aird et al.   Cell Reports

DNA-Damage-Induced Type I Interferon Promotes Senescence and Inhibits Stem Cell Function

(2015) Qiujing Yu et al.   Cell Reports

Simultaneous silencing of multiple RB and p53 pathway members induces cell cycle reentry in intact human pancreatic islets

(2014) Stanley Tamaki et al.   BMC BIOTECHNOLOGY

The Heart: Mostly Postmitotic or Mostly Premitotic? Myocyte Cell Cycle, Senescence, and Quiescence

(2014) Sailay Siddiqi et al.   CANADIAN JOURNAL OF CARDIOLOGY

p21 and p27 a shared senescence history

(2014) Juana María Flores et al.   CELL CYCLE

Temporally distinct roles of ATM and ROS in genotoxic-stress-dependent induction and maintenance of cellular senescence

(2014) R. R. Nair et al.   JOURNAL OF CELL SCIENCE

p27 and Leukemia: Cell Cycle and Beyond

(2014) Anita Roy et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Geriatric muscle stem cells switch reversible quiescence into senescence

(2014) Pedro Sousa-Victor et al.   NATURE

Modelling mammalian cellular quiescence

(2014) G. Yao   Interface Focus

Crosstalk between the Rb Pathway and AKT Signaling Forms a Quiescence-Senescence Switch

(2014) Yoshinori Imai et al.   Cell Reports

RB Maintains Quiescence and Prevents Premature Senescence through Upregulation of DNMT1 in Mesenchymal Stromal Cells

(2014) Shih-Pei Lin et al.   Stem Cell Reports

Stressing the cell cycle in senescence and aging

(2013) Hollie Chandler et al.   CURRENT OPINION IN CELL BIOLOGY

Probing the depths of cellular senescence

(2013) Darren J. Baker et al.   JOURNAL OF CELL BIOLOGY

Hypoxia, MTOR and autophagy

(2012) Mikhail V. Blagosklonny   Autophagy

TIGAR induces p53-mediated cell-cycle arrest by regulation of RB–E2F1 complex

(2012) E Madan et al.   BRITISH JOURNAL OF CANCER

Status of mTOR activity may phenotypically differentiate senescence and quiescence

(2012) Sohee Cho et al.   MOLECULES AND CELLS

The ATM–BID pathway regulates quiescence and survival of haematopoietic stem cells

(2012) Maria Maryanovich et al.   NATURE CELL BIOLOGY

Distinct roles for p107 and p130 in Rb-independent cellular senescence

(2011) Brian D. Lehmann et al.   CELL CYCLE

Loss of p21CDKN1Aimpairs entry to quiescence and activates a DNA damage response in normal fibroblasts induced to quiescence

(2011) Paola Perucca et al.   CELL CYCLE

Differential Roles for the Interferon-Inducible IFI16 and AIM2 Innate Immune Sensors for Cytosolic DNA in Cellular Senescence of Human Fibroblasts

(2011) X. Duan et al.   MOLECULAR CANCER RESEARCH

Elimination of Proliferating Cells Unmasks the Shift from Senescence to Quiescence Caused by Rapamycin

(2011) Olga V. Leontieva et al.   PLoS One

Shifting senescence into quiescence by turning up p53

(2010) Manuel Serrano   CELL CYCLE

Weak p53 permits senescence during cell cycle arrest

(2010) Olga V. Leontieva et al.   CELL CYCLE

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Autophagy mediates the mitotic senescence transition

(2009) A. R.J. Young et al.   GENES & DEVELOPMENT

Activation of p53 by Nutlin-3a, an antagonist of MDM2, induces apoptosis and cellular senescence in adult T-cell leukemia cells

(2009) H Hasegawa et al.   LEUKEMIA

Direct cell reprogramming is a stochastic process amenable to acceleration

(2009) Jacob Hanna et al.   NATURE

Rb2/p130 is the dominating pocket protein in the p53–p21 DNA damage response pathway leading to senescence

(2009) H Helmbold et al.   ONCOGENE

Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network

(2008) Thomas Kuilman et al.   CELL

TSC–mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

(2008) Chong Chen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cellular senescence and organismal aging

(2008) Jessie C. Jeyapalan et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Interferon-γ induces cellular senescence through p53-dependent DNA damage signaling in human endothelial cells

(2008) Kwang Seok Kim et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Many roads lead to oncogene-induced senescence

(2008) S Courtois-Cox et al.   ONCOGENE