Bardet–Biedl Syndrome ciliopathy is linked to altered hematopoiesis and dysregulated self‐tolerance

Adiposity and the risk of rheumatoid arthritis: a systematic review and meta-analysis of cohort studies

(2020) Tomoya Ohno et al.   Scientific Reports

SCAPER localizes to primary cilia and its mutation affects cilia length, causing Bardet-Biedl syndrome

(2019) Ohad Wormser et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Cell circuits and niches controlling B cell development

(2019) Sandra Zehentmeier et al.   IMMUNOLOGICAL REVIEWS

CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing

(2019) Kornel Labun et al.   NUCLEIC ACIDS RESEARCH

Meta‐analysis of genotype‐phenotype associations in Bardet‐Biedl syndrome uncovers differences among causative genes

(2019) Veronika Niederlova et al.   HUMAN MUTATION

The Impact of Obesity on Thyroid Autoimmunity and Dysfunction: A Systematic Review and Meta-Analysis

(2019) Rong-hua Song et al.   Frontiers in Immunology

Transmembrane adaptor protein WBP1L regulates CXCR4 signalling and murine haematopoiesis

(2019) Simon Borna et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Strong homeostatic TCR signals induce formation of self‐tolerant virtual memory CD8 T cells

(2018) Ales Drobek et al.   EMBO JOURNAL

C/EBPγ is dispensable for steady-state and emergency granulopoiesis

(2018) Miroslava Kardosova et al.   HAEMATOLOGICA

BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone

(2018) Fan Ye et al.   JOURNAL OF CELL BIOLOGY

Global epidemiology of hyperthyroidism and hypothyroidism

(2018) Peter N. Taylor et al.   Nature Reviews Endocrinology

The Bardet–Biedl syndrome protein complex is an adapter expanding the cargo range of intraflagellar transport trains for ciliary export

(2018) Peiwei Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

C/EBPγ is dispensable for steady-state and emergency granulopoiesis

(2018) Miroslava Kardosova et al.   HAEMATOLOGICA

Managing Bardet–Biedl Syndrome—Now and in the Future

(2018) Elizabeth Forsythe et al.   Frontiers in Pediatrics

The Ciliary Machinery Is Repurposed for T Cell Immune Synapse Trafficking of LCK

(2018) Louise A. Stephen et al.   DEVELOPMENTAL CELL

Pro-inflammatory cytokines: The link between obesity and osteoarthritis

(2018) Tiantian Wang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Ciliary protein trafficking mediated by IFT and BBSome complexes with the aid of kinesin-2 and dynein-2 motors

(2017) Kazuhisa Nakayama et al.   JOURNAL OF BIOCHEMISTRY

Compounds of psoriasis with obesity and overweight

(2017) Agnieszka Owczarczyk-Saczonek et al.   Postepy Higieny I Medycyny Doswiadczalnej

Cilia and Obesity

(2017) Christian Vaisse et al.   Cold Spring Harbor Perspectives in Biology

A recombinant BBSome core complex and how it interacts with ciliary cargo

(2017) Björn Udo Klink et al.   eLife

The Meckel syndrome- associated protein MKS1 functionally interacts with components of the BBSome and IFT complexes to mediate ciliary trafficking and hedgehog signaling

(2017) Sarah C. Goetz et al.   PLoS One

Copy-Number Variation Contributes to the Mutational Load of Bardet-Biedl Syndrome

(2016) Anna Lindstrand et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Opposing effects of actin signaling and LFA-1 on establishing the affinity threshold for inducing effector T-cell responses in mice

(2016) Ed Palmer et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Caught in a Wnt storm: Complexities of Wnt signaling in hematopoiesis

(2016) Frank J.T. Staal et al.   EXPERIMENTAL HEMATOLOGY

Highly Efficient Mouse Genome Editing by CRISPR Ribonucleoprotein Electroporation of Zygotes

(2016) Sean Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Obesity in IBD: epidemiology, pathogenesis, disease course and treatment outcomes

(2016) Siddharth Singh et al.   Nature Reviews Gastroenterology & Hepatology

Obesity, Type 1 Diabetes, and Psoriasis: An Autoimmune Triple Flip

(2016) Mariagrazia Granata et al.   PATHOBIOLOGY

The BBSome Controls Energy Homeostasis by Mediating the Transport of the Leptin Receptor to the Plasma Membrane

(2016) Deng-Fu Guo et al.   PLoS Genetics

Osteoarthritis

(2016) Johanne Martel-Pelletier et al.   Nature Reviews Disease Primers

Leptin Receptor Signaling in T Cells Is Required for Th17 Differentiation

(2015) Bernardo S. Reis et al.   JOURNAL OF IMMUNOLOGY

IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo

(2015) Omar I. Vivar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Obesity Is a Positive Modulator of IL-6R and IL-6 Expression in the Subcutaneous Adipose Tissue: Significance for Metabolic Inflammation

(2015) Sardar Sindhu et al.   PLoS One

Recurrent CNVs and SNVs at the NPHP1 Locus Contribute Pathogenic Alleles to Bardet-Biedl Syndrome

(2014) Anna Lindstrand et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Obesity in autoimmune diseases: Not a passive bystander

(2014) Mathilde Versini et al.   AUTOIMMUNITY REVIEWS

Specific recycling receptors are targeted to the immune synapse by the intraflagellar transport system

(2014) F. Finetti et al.   JOURNAL OF CELL SCIENCE

Prdm9 Incompatibility Controls Oligospermia and Delayed Fertility but No Selfish Transmission in Mouse Intersubspecific Hybrids

(2014) Petr Flachs et al.   PLoS One

Direct evidence for BBSome-associated intraflagellar transport reveals distinct properties of native mammalian cilia

(2014) Corey L. Williams et al.   Nature Communications

Obesity as a Risk and Severity Factor in Rheumatic Diseases (Autoimmune Chronic Inflammatory Diseases)

(2014) Elisa Gremese et al.   Frontiers in Immunology

Body Mass Index and the Risk for Crohn's Disease and Ulcerative Colitis: Data From a European Prospective Cohort Study (The IBD in EPIC Study)

(2013) Simon S M Chan et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Leptin: molecular mechanisms, systemic pro-inflammatory effects, and clinical implications

(2013) Gilberto Paz-Filho et al.   Arquivos Brasileiros de Endocrinologia e Metabologia

Tissue-Derived Hedgehog Proteins Modulate Th Differentiation and Disease

(2013) A. L. Furmanski et al.   JOURNAL OF IMMUNOLOGY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

The Hedgehog Receptor Patched1 in T Cells Is Dispensable for Adaptive Immunity in Mice

(2013) Kai D. Michel et al.   PLoS One

Hedgehog Signaling Controls T Cell Killing at the Immunological Synapse

(2013) M. de la Roche et al.   SCIENCE

Updated assessment of the prevalence, spectrum and case definition of autoimmune disease

(2012) Scott M. Hayter et al.   AUTOIMMUNITY REVIEWS

BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes

(2012) Qihong Zhang et al.   HUMAN MOLECULAR GENETICS

T Cell Affinity Regulates Asymmetric Division, Effector Cell Differentiation, and Tissue Pathology

(2012) Carolyn G. King et al.   IMMUNITY

The inflammation highway: metabolism accelerates inflammatory traffic in obesity

(2012) Amy R. Johnson et al.   IMMUNOLOGICAL REVIEWS

Intrinsic Protein-Protein Interaction-mediated and Chaperonin-assisted Sequential Assembly of Stable Bardet-Biedl Syndrome Protein Complex, the BBSome

(2012) Qihong Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The BBSome controls IFT assembly and turnaround in cilia

(2012) Qing Wei et al.   NATURE CELL BIOLOGY

The impact of obesity on the immune response to infection

(2012) J. Justin Milner et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Brain tissue- and region-specific abnormalities on volumetric MRI scans in 21 patients with Bardet-Biedl syndrome (BBS)

(2011) Kim M Keppler-Noreuil et al.   BMC Medical Genetics

Regulation of CXCL12 expression by canonical Wnt signaling in bone marrow stromal cells

(2011) Masato Tamura et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Leptin as an immunomodulator

(2011) Claudio Procaccini et al.   MOLECULAR ASPECTS OF MEDICINE

A conditional knockout resource for the genome-wide study of mouse gene function

(2011) William C. Skarnes et al.   NATURE

Phenotypic variability of Bardet-Biedl syndrome: focusing on the kidney

(2011) Audrey Putoux et al.   PEDIATRIC NEPHROLOGY

Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes

(2011) Q. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intraflagellar transport: a new player at the immune synapse

(2011) Francesca Finetti et al.   TRENDS IN IMMUNOLOGY

The Conserved Bardet-Biedl Syndrome Proteins Assemble a Coat that Traffics Membrane Proteins to Cilia

(2010) Hua Jin et al.   CELL

Repression of Hedgehog signal transduction in T-lineage cells increases TCR-induced activation and proliferation

(2010) Nicola J. Rowbotham et al.   CELL CYCLE

Non-redundant role for the transcription factor Gli1 at multiple stages of thymocyte development

(2010) Ekati Drakopoulou et al.   CELL CYCLE

CNS Leptin Action Modulates Immune Response and Survival in Sepsis

(2010) J. Tschop et al.   JOURNAL OF NEUROSCIENCE

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

(2009) Kazuyo Moro et al.   NATURE

Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse

(2009) Francesca Finetti et al.   NATURE CELL BIOLOGY

Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome

(2008) Kamal Rahmouni et al.   JOURNAL OF CLINICAL INVESTIGATION

Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia

(2008) N. F. Berbari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA