The Meckel syndrome- associated protein MKS1 functionally interacts with components of the BBSome and IFT complexes to mediate ciliary trafficking and hedgehog signaling
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Meckel syndrome- associated protein MKS1 functionally interacts with components of the BBSome and IFT complexes to mediate ciliary trafficking and hedgehog signaling
Authors
Keywords
-
Journal
PLoS One
Volume 12, Issue 3, Pages e0173399
Publisher
Public Library of Science (PLoS)
Online
2017-03-15
DOI
10.1371/journal.pone.0173399
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A Screen for Modifiers of Cilia Phenotypes Reveals Novel MKS Alleles and Uncovers a Specific Genetic Interaction between osm-3 and nphp-4
- (2016) Svetlana V. Masyukova et al. PLoS Genetics
- A Potential Contributory Role for Ciliary Dysfunction in the 16p11.2 600 kb BP4-BP5 Pathology
- (2015) Eugenia Migliavacca et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Modulation of Ciliary Phosphoinositide Content Regulates Trafficking and Sonic Hedgehog Signaling Output
- (2015) Marcelo Chávez et al. DEVELOPMENTAL CELL
- Exploring genotype-phenotype relationships in Bardet-Biedl syndrome families
- (2015) Sheila Castro-Sánchez et al. JOURNAL OF MEDICAL GENETICS
- IFT81, encoding an IFT-B core protein, as a very rare cause of a ciliopathy phenotype
- (2015) Isabelle Perrault et al. JOURNAL OF MEDICAL GENETICS
- Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary Signaling
- (2015) Laura E. Yee et al. PLoS Genetics
- Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly
- (2014) Michael Taschner et al. JOURNAL OF CELL BIOLOGY
- The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment
- (2014) Mu He et al. NATURE CELL BIOLOGY
- Defects in the IFT-B Component IFT172 Cause Jeune and Mainzer-Saldino Syndromes in Humans
- (2013) Jan Halbritter et al. AMERICAN JOURNAL OF HUMAN GENETICS
- BBS7 is required for BBSome formation and its absence in mice results in Bardet-Biedl syndrome phenotypes and selective abnormalities in membrane protein trafficking
- (2013) Q. Zhang et al. JOURNAL OF CELL SCIENCE
- Molecular Basis of Tubulin Transport Within the Cilium by IFT74 and IFT81
- (2013) S. Bhogaraju et al. SCIENCE
- The Spinocerebellar Ataxia-Associated Gene Tau Tubulin Kinase 2 Controls the Initiation of Ciliogenesis
- (2012) Sarah C. Goetz et al. CELL
- The ciliopathies: a transitional model into systems biology of human genetic disease
- (2012) Erica E Davis et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes
- (2012) Qihong Zhang et al. HUMAN MOLECULAR GENETICS
- A Simple Cell-Based Assay Reveals That Diverse Neuropsychiatric Risk Genes Converge on Primary Cilia
- (2012) Aaron Marley et al. PLoS One
- ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting
- (2012) M. C. Humbert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Architecture and function of IFT complex proteins in ciliogenesis
- (2011) Michael Taschner et al. DIFFERENTIATION
- A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus
- (2011) J. M. Friedland-Little et al. HUMAN MOLECULAR GENETICS
- A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain
- (2011) Ben Chih et al. NATURE CELL BIOLOGY
- TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum
- (2011) Erica E Davis et al. NATURE GENETICS
- A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition
- (2011) Francesc R Garcia-Gonzalo et al. NATURE GENETICS
- Complex interactions between genes controlling trafficking in primary cilia
- (2011) Polloneal Jymmiel R Ocbina et al. NATURE GENETICS
- A Novel Protein LZTFL1 Regulates Ciliary Trafficking of the BBSome and Smoothened
- (2011) Seongjin Seo et al. PLoS Genetics
- The Conserved Bardet-Biedl Syndrome Proteins Assemble a Coat that Traffics Membrane Proteins to Cilia
- (2010) Hua Jin et al. CELL
- Dopamine receptor 1 localizes to neuronal cilia in a dynamic process that requires the Bardet-Biedl syndrome proteins
- (2010) Jacqueline S. Domire et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Neuronal ciliary signaling in homeostasis and disease
- (2010) Jill A. Green et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The primary cilium: a signalling centre during vertebrate development
- (2010) Sarah C. Goetz et al. NATURE REVIEWS GENETICS
- BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly
- (2010) S. Seo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Making sense of cilia in disease: The human ciliopathies
- (2009) Kate Baker et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS
- The Vertebrate Primary Cilium in Development, Homeostasis, and Disease
- (2009) Jantje M. Gerdes et al. CELL
- A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling
- (2009) Scott D. Weatherbee et al. HUMAN MOLECULAR GENETICS
- TheChlamydomonas reinhardtiiBBSome is an IFT cargo required for export of specific signaling proteins from flagella
- (2009) Karl-Ferdinand Lechtreck et al. JOURNAL OF CELL BIOLOGY
- Functional interactions between the ciliopathy-associated Meckel syndrome 1 (MKS1) protein and two novel MKS1-related (MKSR) proteins
- (2009) N. J. Bialas et al. JOURNAL OF CELL SCIENCE
- INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse
- (2009) Monique Jacoby et al. NATURE GENETICS
- Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies
- (2009) Stephanie L Bielas et al. NATURE GENETICS
- Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling
- (2009) K. F. Liem et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Joubert Syndrome: Insights Into Brain Development, Cilium Biology, and Complex Disease
- (2009) Dan Doherty Seminars in Pediatric Neurology
- FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism
- (2008) Ahryon Cho et al. DEVELOPMENTAL BIOLOGY
- The homodimeric kinesin, Kif17, is essential for vertebrate photoreceptor sensory outer segment development
- (2008) Christine Insinna et al. DEVELOPMENTAL BIOLOGY
- Intraflagellar transport, cilia, and mammalian Hedgehog signaling: Analysis in mouse embryonic fibroblasts
- (2008) Polloneal Jymmiel R. Ocbina et al. DEVELOPMENTAL DYNAMICS
- Assembly of primary cilia
- (2008) Lotte B. Pedersen et al. DEVELOPMENTAL DYNAMICS
- Association of common variants in the Joubert syndrome gene (AHI1) with autism
- (2008) Ana I. Alvarez Retuerto et al. HUMAN MOLECULAR GENETICS
- Intraflagellar transport motors in cilia: moving along the cell's antenna
- (2008) Jonathan M. Scholey JOURNAL OF CELL BIOLOGY
- Hypomorphic mutations in syndromic encephalocele genes are associated with Bardet-Biedl syndrome
- (2008) Carmen C Leitch et al. NATURE GENETICS
- THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia
- (2008) Pamela V Tran et al. NATURE GENETICS
- Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia
- (2008) N. F. Berbari et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search