- Home
- Publications
- Publication Search
- Publication Details
Title
Inhibiting ferroptosis: A novel approach for stroke therapeutics
Authors
Keywords
-
Journal
DRUG DISCOVERY TODAY
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-01-10
DOI
10.1016/j.drudis.2020.12.020
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Energy-stress-mediated AMPK activation inhibits ferroptosis
- (2020) Hyemin Lee et al. NATURE CELL BIOLOGY
- Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis
- (2020) Yilong Zou et al. Nature Chemical Biology
- Polyunsaturated Fatty Acid Deuteration against Neurodegeneration
- (2020) Mikhail S. Shchepinov TRENDS IN PHARMACOLOGICAL SCIENCES
- Ferroptosis: past, present and future
- (2020) Jie Li et al. Cell Death & Disease
- Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers
- (2020) Mariluz Soula et al. Nature Chemical Biology
- Ferroptosis in Neurological Diseases
- (2020) Jia-Xin Ren et al. Frontiers in Cellular Neuroscience
- Targeting Ferroptosis: New Hope for As-Yet-Incurable Diseases
- (2020) Marcus Conrad et al. TRENDS IN MOLECULAR MEDICINE
- Structure-activity relationship studies of phenothiazine derivatives as a new class of ferroptosis inhibitors together with the therapeutic effect in an ischemic stroke model
- (2020) Wei Yang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Ferroptosis as a target for protection against cardiomyopathy
- (2019) Xuexian Fang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Threshold protective effect of deuterated polyunsaturated fatty acids on peroxidation of lipid bilayers
- (2019) Alexander M. Firsov et al. FEBS Journal
- Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion
- (2019) Yang Li et al. CELL DEATH AND DIFFERENTIATION
- Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke
- (2019) Ishraq Alim et al. CELL
- ESCRT-III–dependent membrane repair blocks ferroptosis
- (2019) Enyong Dai et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cu II (atsm) inhibits ferroptosis: implications for treatment of neurodegenerative disease
- (2019) Authors Adam Southon et al. BRITISH JOURNAL OF PHARMACOLOGY
- FSP1 is a glutathione-independent ferroptosis suppressor
- (2019) Sebastian Doll et al. NATURE
- The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
- (2019) Kirill Bersuker et al. NATURE
- The chemical basis of ferroptosis
- (2019) Marcus Conrad et al. Nature Chemical Biology
- GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling
- (2019) Vanessa A. N. Kraft et al. ACS Central Science
- Role of dopamine on functional recovery in the contralateral hemisphere after focal stroke in the somatosensory cortex
- (2018) Kisho Obi et al. BRAIN RESEARCH
- Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis
- (2018) Irina Ingold et al. CELL
- Design, synthesis, and evaluation of NDGA analogues as potential anti-ischemic stroke agents
- (2018) Lili Huang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Selenium and GPX4, a vital symbiosis
- (2018) José Pedro Friedmann Angeli et al. FREE RADICAL BIOLOGY AND MEDICINE
- Cell growth potential drives ferroptosis susceptibility in rhabdomyosarcoma and myoblast cell lines
- (2018) Silvia Codenotti et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Randomized, clinical trial of RT001: Early signals of efficacy in Friedreich's ataxia
- (2018) Theresa Zesiewicz et al. MOVEMENT DISORDERS
- O-Phenylenediamine: a privileged pharmacophore of ferrostatins for radical-trapping reactivity in blocking ferroptosis
- (2018) Xie-Huang Sheng et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Synergistic neuroprotective effect of rasagiline and idebenone against retinal ischemia-reperfusion injury via the Lin28-let-7-Dicer pathway
- (2018) Dawei Lei et al. Oncotarget
- Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis
- (2018) Ron Shah et al. ACS Central Science
- Glutathione peroxidase 4 participates in secondary brain injury through mediating ferroptosis in a rat model of intracerebral hemorrhage
- (2018) Zhuwei Zhang et al. BRAIN RESEARCH
- AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity
- (2018) Xinxin Song et al. CURRENT BIOLOGY
- AMPK: Potential Therapeutic Target for Ischemic Stroke
- (2018) Shuai Jiang et al. Theranostics
- N-acetylcysteine targets 5 lipoxygenase-derived, toxic lipids and can synergize with prostaglandin E2 to inhibit ferroptosis and improve outcomes following hemorrhagic stroke in mice
- (2018) Saravanan S. Karuppagounder et al. ANNALS OF NEUROLOGY
- Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy
- (2018) Lars Devisscher et al. JOURNAL OF MEDICINAL CHEMISTRY
- Tau-mediated iron export prevents ferroptotic damage after ischemic stroke
- (2017) Q-z Tuo et al. MOLECULAR PSYCHIATRY
- 12/15-Lipoxygenase Inhibition or Knockout Reduces Warfarin-Associated Hemorrhagic Transformation After Experimental Stroke
- (2017) Yu Liu et al. STROKE
- Neuronal Death After Hemorrhagic Stroke In Vitro and In Vivo Shares Features of Ferroptosis and Necroptosis
- (2017) Marietta Zille et al. STROKE
- Ferroptosis Inhibition: Mechanisms and Opportunities
- (2017) Jose Pedro Friedmann Angeli et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity
- (2017) Yangchun Xie et al. Cell Reports
- Treatment with the PPARγ Agonist Pioglitazone in the Early Post-ischemia Phase Inhibits Pro-inflammatory Responses and Promotes Neurogenesis Via the Activation of Innate- and Bone Marrow-Derived Stem Cells in Rats
- (2017) Tomoya Kinouchi et al. Translational Stroke Research
- On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death
- (2017) Omkar Zilka et al. ACS Central Science
- Autophagy promotes ferroptosis by degradation of ferritin
- (2016) Wen Hou et al. Autophagy
- Antiferroptotic activity of non-oxidative dopamine
- (2016) Ding Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Therapies targeting lipid peroxidation in traumatic brain injury
- (2016) Tamil Selvan Anthonymuthu et al. BRAIN RESEARCH
- Deferoxamine inhibits microglial activation, attenuates blood-brain barrier disruption, rescues dendritic damage, and improves spatial memory in a mouse model of microhemorrhages
- (2016) Xiao-fei He et al. JOURNAL OF NEUROCHEMISTRY
- Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
- (2016) Valerian E Kagan et al. Nature Chemical Biology
- ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
- (2016) Sebastian Doll et al. Nature Chemical Biology
- Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis
- (2016) Kenichi Shimada et al. Nature Chemical Biology
- 5-LOX Inhibitor Zileuton Reduces Inflammatory Reaction and Ischemic Brain Damage Through the Activation of PI3K/Akt Signaling Pathway
- (2016) Xian-kun Tu et al. NEUROCHEMICAL RESEARCH
- Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
- (2016) Wan Seok Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ferroptosis: Death by Lipid Peroxidation
- (2016) Wan Seok Yang et al. TRENDS IN CELL BIOLOGY
- Acute Ischemic Stroke Severity, Progression, and Outcome Relate to Changes in Dipeptidyl Peptidase IV and Fibroblast Activation Protein Activity
- (2016) Lesley Baerts et al. Translational Stroke Research
- A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis
- (2016) Tanja Krainz et al. ACS Central Science
- Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death
- (2015) Scott J. Dixon et al. ACS Chemical Biology
- Expression of Inactive Glutathione Peroxidase 4 Leads to Embryonic Lethality, and Inactivation of the Alox15 Gene Does Not Rescue Such Knock-In Mice
- (2015) Simone Hanna Brütsch et al. ANTIOXIDANTS & REDOX SIGNALING
- The 5-lipoxygenase (5-LOX) Inhibitor Zileuton Reduces Inflammation and Infarct Size with Improvement in Neurological Outcome Following Cerebral Ischemia
- (2015) Bruno Silva et al. CURRENT NEUROVASCULAR RESEARCH
- Isotope-reinforced polyunsaturated fatty acids protect mitochondria from oxidative stress
- (2015) Alexander Y. Andreyev et al. FREE RADICAL BIOLOGY AND MEDICINE
- Glucagon-Like Receptor 1 Agonists and DPP-4 Inhibitors: Potential Therapies for the Treatment of Stroke
- (2015) Vladimer Darsalia et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Novel Stroke Therapeutics: Unraveling Stroke Pathophysiology and Its Impact on Clinical Treatments
- (2015) Paul M. George et al. NEURON
- Guidelines for the Management of Spontaneous Intracerebral Hemorrhage
- (2015) J. Claude Hemphill et al. STROKE
- Advances in Radical-Trapping Antioxidant Chemistry in the 21st Century: A Kinetics and Mechanisms Perspective
- (2014) Keith U. Ingold et al. CHEMICAL REVIEWS
- Deciphering of Mitochondrial Cardiolipin Oxidative Signaling in Cerebral Ischemia-Reperfusion
- (2014) Jing Ji et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Potent and Selective Inhibitors of Human Reticulocyte 12/15-Lipoxygenase as Anti-Stroke Therapies
- (2014) Ganesha Rai et al. JOURNAL OF MEDICINAL CHEMISTRY
- Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials
- (2014) Jonathan Emberson et al. LANCET
- Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
- (2014) Jose Pedro Friedmann Angeli et al. NATURE CELL BIOLOGY
- Oxidative Stress in Alzheimer’s Disease: Why Did Antioxidant Therapy Fail?
- (2014) Torbjörn Persson et al. Oxidative Medicine and Cellular Longevity
- Linagliptin enhances neural stem cell proliferation after stroke in type 2 diabetic mice
- (2014) Vladimer Darsalia et al. REGULATORY PEPTIDES
- KLF11 mediates PPARγ cerebrovascular protection in ischaemic stroke
- (2013) Ke-Jie Yin et al. BRAIN
- A Perspective on Free Radical Autoxidation: The Physical Organic Chemistry of Polyunsaturated Fatty Acid and Sterol Peroxidation
- (2013) Ned A. Porter JOURNAL OF ORGANIC CHEMISTRY
- Evaluation of Selenite Effects on Selenoproteins and Cytokinome in Human Hepatoma Cell Lines
- (2013) Fabiola Rusolo et al. MOLECULES
- Inhibition of 12/15-lipoxygenase as therapeutic strategy to treat stroke
- (2012) Kazim Yigitkanli et al. ANNALS OF NEUROLOGY
- Glutathione synthesis
- (2012) Shelly C. Lu BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia
- (2012) Peter Röhnert et al. Journal of Neuroinflammation
- Incorporation of Ring Nitrogens into Diphenylamine Antioxidants: Striking a Balance between Reactivity and Stability
- (2012) Jason J. Hanthorn et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- AMPK: a nutrient and energy sensor that maintains energy homeostasis
- (2012) D. Grahame Hardie et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Free Radical Lipid Peroxidation: Mechanisms and Analysis
- (2011) Huiyong Yin et al. CHEMICAL REVIEWS
- Blood-derived iron mediates free radical production and neuronal death in the hippocampal CA1 area following transient forebrain ischemia in rat
- (2010) Ui Jin Park et al. ACTA NEUROPATHOLOGICA
- Isotope-reinforced polyunsaturated fatty acids protect yeast cells from oxidative stress
- (2010) Shauna Hill et al. FREE RADICAL BIOLOGY AND MEDICINE
- Hemoglobin and Iron Handling in Brain after Subarachnoid Hemorrhage and the Effect of Deferoxamine on Early Brain Injury
- (2010) Jin-Yul Lee et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Peroxisome-proliferator-activated receptors γ and peroxisome-proliferator-activated receptors β/δ and the regulation of interleukin 1 receptor antagonist expression by pioglitazone in ischaemic brain
- (2010) Torben Glatz et al. JOURNAL OF HYPERTENSION
- Effects of tetrahydrobiopterin on cerebral infarction after transient focal ischemia in rats
- (2010) Ling-Ling Tang et al. NEUROLOGICAL RESEARCH
- The Science of Stroke: Mechanisms in Search of Treatments
- (2010) Michael A. Moskowitz et al. NEURON
- Deferoxamine Treatment for Intracerebral Hemorrhage in Aged Rats
- (2010) Masanobu Okauchi et al. STROKE
- Effects of deferoxamine on brain injury after transient focal cerebral ischemia in rats with hyperglycemia
- (2009) Yingqi Xing et al. BRAIN RESEARCH
- Binding of arachidonic acid and two flavonoid inhibitors to human 12- and 15-lipoxygenases: a steered molecular dynamics study
- (2009) Carolina Mascayano et al. JOURNAL OF MOLECULAR MODELING
- Arachidonyl Trifluoromethyl Ketone Is Neuroprotective after Spinal Cord Injury
- (2009) Wenlong Huang et al. JOURNAL OF NEUROTRAUMA
- Intracerebral haemorrhage
- (2009) Adnan I Qureshi et al. LANCET
- Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death
- (2008) Alexander Seiler et al. Cell Metabolism
- Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells
- (2008) Wan Seok Yang et al. CHEMISTRY & BIOLOGY
- Peroxisome proliferator-activated receptorsγ (PPARγ) differently modulate the interleukin-6 expression in the peri-infarct cortical tissue in the acute and delayed phases of cerebral ischaemia
- (2008) Andreas Patzer et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Protecting Against Cerebrovascular Injury
- (2008) Guang Jin et al. STROKE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now