Enteroendocrine cells sense bacterial tryptophan catabolites to activate enteric and vagal neuronal pathways

Gut Microbial Metabolites of Aromatic Amino Acids as Signals in Host–Microbe Interplay

(2020) Yali Liu et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The duodenal microbiome is altered in small intestinal bacterial overgrowth

(2020) Gabriela Leite et al.   PLoS One

Vitamin B12 and folic acid alleviate symptoms of nutritional deficiency by antagonizing aryl hydrocarbon receptor

(2020) Daniel J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intestinal Serum amyloid A suppresses systemic neutrophil activation and bactericidal activity in response to microbiota colonization

(2019) Caitlin C. Murdoch et al.   PLoS Pathogens

Gut Microbe to Brain Signaling: What Happens in Vagus…

(2019) Christine Fülling et al.   NEURON

Comparison of Human and Murine Enteroendocrine Cells by Transcriptomic and Peptidomic Profiling

(2019) Geoffrey P. Roberts et al.   DIABETES

A Cellular-Resolution Atlas of the Larval Zebrafish Brain

(2019) Michael Kunst et al.   NEURON

Epithelial delamination is protective during pharmaceutical-induced enteropathy

(2019) Scott T. Espenschied et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small Intestinal Bacterial Overgrowth in Children: A State-Of-The-Art Review

(2019) David Avelar Rodriguez et al.   Frontiers in Pediatrics

Aryl Hydrocarbon Receptor Modulation by Tuberculosis Drugs Impairs Host Defense and Treatment Outcomes

(2019) Andreas Puyskens et al.   Cell Host & Microbe

The zebrafish as a model for gastrointestinal tract–microbe interactions

(2019) Erika M. Flores et al.   CELLULAR MICROBIOLOGY

Activation of aryl hydrocarbon receptor by dioxin directly shifts gut microbiota in zebrafish

(2019) Yumiao Sun et al.   ENVIRONMENTAL POLLUTION

The Cellular Diversity and Transcription Factor Code of Drosophila Enteroendocrine Cells

(2019) Xingting Guo et al.   Cell Reports

High fat diet induces microbiota-dependent silencing of enteroendocrine cells

(2019) Lihua Ye et al.   eLife

Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion

(2018) Yogesh Bhattarai et al.   Cell Host & Microbe

Deletion of choline acetyltransferase in enteric neurons results in postnatal intestinal dysmotility and dysbiosis

(2018) Carl D. Johnson et al.   FASEB JOURNAL

Image velocimetry and spectral analysis enable quantitative characterization of larval zebrafish gut motility

(2018) J. Ganz et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Genetic studies to re-affiliate Edwardsiella tarda fish isolates to Edwardsiella piscicida and Edwardsiella anguillarum species

(2018) Noemí Buján et al.   SYSTEMATIC AND APPLIED MICROBIOLOGY

Indole, a Signaling Molecule Produced by the Gut Microbiota, Negatively Impacts Emotional Behaviors in Rats

(2018) Mathilde Jaglin et al.   Frontiers in Neuroscience

The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis

(2018) Bruno Bonaz et al.   Frontiers in Neuroscience

Bacterial Signaling at the Intestinal Epithelial Interface in Inflammation and Cancer

(2018) Olivia I. Coleman et al.   Frontiers in Immunology

Brain Aromatase Modulates Serotonergic Neuron by Regulating Serotonin Levels in Zebrafish Embryos and Larvae

(2018) Zulvikar Syambani Ulhaq et al.   Frontiers in Endocrinology

Vagus Nerve as Modulator of the Brain–Gut Axis in Psychiatric and Inflammatory Disorders

(2018) Sigrid Breit et al.   Frontiers in Psychiatry

A Neural Circuit for Gut-Induced Reward

(2018) Wenfei Han et al.   CELL

A gut-brain neural circuit for nutrient sensory transduction

(2018) Melanie Maya Kaelberer et al.   SCIENCE

Protective effects of folic acid on PM2.5-induced cardiac developmental toxicity in zebrafish embryos by targeting AhR and Wnt/β-catenin signal pathways

(2017) Cong Yue et al.   ENVIRONMENTAL TOXICOLOGY

Small Intestinal Bacterial Overgrowth and Irritable Bowel Syndrome: A Bridge between Functional Organic Dichotomy

(2017) Uday C. Ghoshal et al.   Gut and Liver

A single-cell survey of the small intestinal epithelium

(2017) Adam L. Haber et al.   NATURE

The enteric nervous system promotes intestinal health by constraining microbiota composition

(2017) Annah S. Rolig et al.   PLOS BIOLOGY

From Whole-Brain Data to Functional Circuit Models: The Zebrafish Optomotor Response

(2016) Eva A. Naumann et al.   CELL

Multicolor mapping of the cardiomyocyte proliferation dynamics that construct the atrium

(2016) Matthew J. Foglia et al.   DEVELOPMENT

Macrophage Epithelial Reprogramming Underlies Mycobacterial Granuloma Formation and Promotes Infection

(2016) Mark R. Cronan et al.   IMMUNITY

Vagal neurocircuitry and its influence on gastric motility

(2016) R. Alberto Travagli et al.   Nature Reviews Gastroenterology & Hepatology

The Gut Microbial Endocrine Organ: Bacterially Derived Signals Driving Cardiometabolic Diseases

(2015) J. Mark Brown et al.   Annual Review of Medicine

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

(2015) Jessica M. Yano et al.   CELL

The composition of the zebrafish intestinal microbial community varies across development

(2015) W Zac Stephens et al.   ISME Journal

Neuroepithelial circuit formed by innervation of sensory enteroendocrine cells

(2015) Diego V. Bohórquez et al.   JOURNAL OF CLINICAL INVESTIGATION

Whole-brain activity mapping onto a zebrafish brain atlas

(2015) Owen Randlett et al.   NATURE METHODS

Serotonin-secreting enteroendocrine cells respond via diverse mechanisms to acute and chronic changes in glucose availability

(2015) Leah Zelkas et al.   Nutrition & Metabolism

Labeling of active neural circuits in vivo with designed calcium integrators

(2015) B. F. Fosque et al.   SCIENCE

Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles

(2015) Troy D. Hubbard et al.   Scientific Reports

Single continuous lumen formation in the zebrafish gut is mediated by smoothened-dependent tissue remodeling

(2014) A. L. Alvers et al.   DEVELOPMENT

Breath tests in the diagnosis of small intestinal bacterial overgrowth in patients with irritable bowel syndrome in comparison with quantitative upper gut aspirate culture

(2014) Uday C. Ghoshal et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Mechanisms of activation of mouse and human enteroendocrine cells by nutrients

(2014) Erin L Symonds et al.   GUT

Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4

(2014) Madhukumar Venkatesh et al.   IMMUNITY

Host–microbe interactions shaping the gastrointestinal environment

(2014) Gerard E. Kaiko et al.   TRENDS IN IMMUNOLOGY

Enhanced Cell-Specific Ablation in Zebrafish Using a Triple Mutant of Escherichia Coli Nitroreductase

(2014) Jonathan R. Mathias et al.   Zebrafish

TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins

(2014) Victor Meseguer et al.   Nature Communications

Bacterial Metabolite Indole Modulates Incretin Secretion from Intestinal Enteroendocrine L Cells

(2014) Catalin Chimerel et al.   Cell Reports

Comparative genomics reveals that a fish pathogenic bacterium Edwardsiella tarda has acquired the locus of enterocyte effacement (LEE) through horizontal gene transfer

(2013) Yoji Nakamura et al.   BMC GENOMICS

Loss of ascl1a prevents secretory cell differentiation within the zebrafish intestinal epithelium resulting in a loss of distal intestinal motility

(2013) Gillian Roach et al.   DEVELOPMENTAL BIOLOGY

The role of SOX10 during enteric nervous system development

(2013) Nadege Bondurand et al.   DEVELOPMENTAL BIOLOGY

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

(2013) Teresa Zelante et al.   IMMUNITY

Photochemical activation of TRPA1 channels in neurons and animals

(2013) David Kokel et al.   Nature Chemical Biology

Extrinsic primary afferent signalling in the gut

(2013) Simon J. H. Brookes et al.   Nature Reviews Gastroenterology & Hepatology

The gut as a sensory organ

(2013) John B. Furness et al.   Nature Reviews Gastroenterology & Hepatology

5-Hydroxytryptamine (serotonin) in the gastrointestinal tract

(2013) Michael D. Gershon   Current Opinion in Endocrinology Diabetes and Obesity

TRPA1: A Gatekeeper for Inflammation

(2012) Diana M. Bautista et al.   Annual Review of Physiology

The role of TRPA1 in visceral inflammation and pain

(2012) Tamia K. Lapointe et al.   Channels

Edwardsiella piscicida sp. nov.,a novel species pathogenic to fish

(2012) T. Abayneh et al.   JOURNAL OF APPLIED MICROBIOLOGY

Clonally dominant cardiomyocytes direct heart morphogenesis

(2012) Vikas Gupta et al.   NATURE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Postembryonic neuronal addition in Zebrafish dorsal root ganglia is regulated by Notch signaling

(2012) Hillary McGraw et al.   Neural Development

Edwardsiella Comparative Phylogenomics Reveal the New Intra/Inter-Species Taxonomic Relationships, Virulence Evolution and Niche Adaptation Mechanisms

(2012) Minjun Yang et al.   PLoS One

Spatial organization of the extracellular matrix regulates cell-cell junction positioning

(2012) Q. Tseng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ret signalling integrates a craniofacial muscle module during development

(2011) R. D. Knight et al.   DEVELOPMENT

Robo2 determines subtype-specific axonal projections of trigeminal sensory neurons

(2011) Y. A. Pan et al.   DEVELOPMENT

Essential Roles of Enteric Neuronal Serotonin in Gastrointestinal Motility and the Development/Survival of Enteric Dopaminergic Neurons

(2011) Z. Li et al.   JOURNAL OF NEUROSCIENCE

The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication

(2011) P. Bercik et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

(2011) J. A. Bravo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRP Channels in the Digestive System

(2010) Peter Holzer   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Irritating channels: the case of TRPA1

(2010) Bernd Nilius et al.   JOURNAL OF PHYSIOLOGY-LONDON

The nucleus tractus solitarius: a portal for visceral afferent signal processing, energy status assessment and integration of their combined effects on food intake

(2009) H J Grill et al.   INTERNATIONAL JOURNAL OF OBESITY

TRPA1 regulates gastrointestinal motility through serotonin release from enterochromaffin cells

(2009) K. Nozawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunohistochemical analysis of neuron types in the mouse small intestine

(2008) Zheng-Dong Qu et al.   CELL AND TISSUE RESEARCH

Indole and other aromatic compounds activate the yeast TRPY1 channel

(2008) W. John Haynes et al.   FEBS LETTERS

Zebrafish TRPA1 Channels Are Required for Chemosensation But Not for Thermosensation or Mechanosensory Hair Cell Function

(2008) D. A. Prober et al.   JOURNAL OF NEUROSCIENCE

Methods for generating and colonizing gnotobiotic zebrafish

(2008) Linh N Pham et al.   Nature Protocols