The gut as a sensory organ

Activation of FFA1 mediates GLP-1 secretion in mice. Evidence for allosterism at FFA1

(2013) Yumei Xiong et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Proton-coupled oligopeptide transporter family SLC15: Physiological, pharmacological and pathological implications

(2013) David E. Smith et al.   MOLECULAR ASPECTS OF MEDICINE

Extrinsic primary afferent signalling in the gut

(2013) Simon J. H. Brookes et al.   Nature Reviews Gastroenterology & Hepatology

Role of fatty acid transport protein 4 in oleic acid-induced glucagon-like peptide-1 secretion from murine intestinal L cells

(2012) M. A. Poreba et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Irritable Bowel Syndrome: Methods, Mechanisms, and Pathophysiology. Neural and neuro-immune mechanisms of visceral hypersensitivity in irritable bowel syndrome

(2012) Bin Feng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Sensing of amino acids by the gut-expressed taste receptor T1R1-T1R3 stimulates CCK secretion

(2012) Kristian Daly et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Enhancement of CGRP sensory afferent innervation in the gut during the development of food allergy in an experimental murine model

(2012) Jaemin Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Peripheral neural targets in obesity

(2012) Amanda J Page et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effects of JNJ-38431055, a novel GPR119 receptor agonist, in randomized, double-blind, placebo-controlled studies in subjects with type 2 diabetes

(2012) L. B. Katz et al.   DIABETES OBESITY & METABOLISM

Disruption of the MurineGlp2rImpairs Paneth Cell Function and Increases Susceptibility to Small Bowel Enteritis

(2012) Seung-Jun Lee et al.   ENDOCRINOLOGY

A Beautiful Cell (or Two or Three?)

(2012) Patricia L. Brubaker   ENDOCRINOLOGY

Intestinotrophic Glucagon-Like Peptide-2 (GLP-2) Activates Intestinal Gene Expression and Growth Factor-Dependent Pathways Independent of the Vasoactive Intestinal Peptide Gene in Mice

(2012) Bernardo Yusta et al.   ENDOCRINOLOGY

The vagal innervation of the gut and immune homeostasis

(2012) Gianluca Matteoli et al.   GUT

Gastrointestinal chemosensation: chemosensory cells in the alimentary tract

(2012) H. Breer et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Unraveling oxyntomodulin, GLP1's enigmatic brother

(2012) Alessandro Pocai   JOURNAL OF ENDOCRINOLOGY

Sense of Taste in the Gastrointestinal Tract

(2012) Ken Iwatsuki et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Intestinal fatty acid infusion modulates food preference as well as calorie intake via the vagal nerve and midbrain–hypothalamic neural pathways in rats

(2012) Nobuya Ogawa et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Vitamins prime immunity

(2012) Wei-Jen Chua et al.   NATURE

The enteric nervous system and neurogastroenterology

(2012) John B. Furness   Nature Reviews Gastroenterology & Hepatology

Co-dependents: MR1-restricted MAIT cells and their antimicrobial function

(2012) Marielle C. Gold et al.   NATURE REVIEWS MICROBIOLOGY

The Glucagon Receptor Is Involved in Mediating the Body Weight-Lowering Effects of Oxyntomodulin

(2012) Jennifer R. Kosinski et al.   Obesity

Mechanosensitive Enteric Neurons in the Myenteric Plexus of the Mouse Intestine

(2012) Gemma Mazzuoli et al.   PLoS One

Therapeutic potential of anamorelin, a novel, oral ghrelin mimetic, in patients with cancer-related cachexia: a multicenter, randomized, double-blind, crossover, pilot study

(2012) José M. Garcia et al.   SUPPORTIVE CARE IN CANCER

Nutrient sensing in the gut: new roads to therapeutics?

(2012) Sara Janssen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Receptors Responsive to Protein Breakdown Products in G-Cells and D-Cells of Mouse, Swine and Human

(2012) Désirée Christine Haid et al.   Frontiers in Physiology

Detecting sweet and umami tastes in the gastrointestinal tract

(2011) K. Iwatsuki et al.   Acta Physiologica

Standard magnetic resonance-based measurements of the Pi→ATP rate do not index the rate of oxidative phosphorylation in cardiac and skeletal muscles

(2011) Arthur H. L. From et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

l-Mimosine blocks cell proliferation via upregulation of B-cell translocation gene 2 and N-myc downstream regulated gene 1 in prostate carcinoma cells

(2011) Li-Chuan Chung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Na+-D-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion

(2011) V. Gorboulev et al.   DIABETES

Efficacy and Safety of Exenatide Once Weekly Versus Metformin, Pioglitazone, and Sitagliptin Used as Monotherapy in Drug-Naive Patients With Type 2 Diabetes (DURATION-4): A 26-week double-blind study

(2011) D. Russell-Jones et al.   DIABETES CARE

Up-Regulated Expression of Advanced Glycation End-Products and Their Receptor in the Small Intestine and Colon of Diabetic Rats

(2011) Pengmin Chen et al.   DIGESTIVE DISEASES AND SCIENCES

Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and/or intravenous fluid requirements in patients with short bowel syndrome

(2011) P. B. Jeppesen et al.   GUT

Nutrient sensing receptors in gastric endocrine cells

(2011) Désirée Haid et al.   JOURNAL OF MOLECULAR HISTOLOGY

Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis

(2011) Charles L. Bevins et al.   NATURE REVIEWS MICROBIOLOGY

Vagal intramuscular array afferents form complexes with interstitial cells of Cajal in gastrointestinal smooth muscle: analogues of muscle spindle organs?

(2011) T.L. Powley et al.   NEUROSCIENCE

Nutrient detection by incretin hormone secreting cells

(2011) Eleftheria Diakogiannaki et al.   PHYSIOLOGY & BEHAVIOR

Bitter taste receptors and α-gustducin regulate the secretion of ghrelin with functional effects on food intake and gastric emptying

(2011) Sara Janssen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucose sensing and signalling; regulation of intestinal glucose transport

(2011) S. P. Shirazi-Beechey et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

A diet based on high-heat-treated foods promotes risk factors for diabetes mellitus and cardiovascular diseases

(2010) Inès Birlouez-Aragon et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Amino acids stimulate cholecystokinin release through the Ca2+-sensing receptor

(2010) Yu Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Rapid Upregulation of Sodium-Glucose Transporter SGLT1 in Response to Intestinal Sweet Taste Stimulation

(2010) Adam T. Stearns et al.   ANNALS OF SURGERY

Adaptive Immune Regulation in the Gut: T Cell–Dependent and T Cell–Independent IgA Synthesis

(2010) Sidonia Fagarasan et al.   Annual Review of Immunology

Homeostasis and Inflammation in the Intestine

(2010) Wendy S. Garrett et al.   CELL

T1R3 is expressed in brush cells and ghrelin-producing cells of murine stomach

(2010) Nicole Hass et al.   CELL AND TISSUE RESEARCH

Peptide YY Is Critical for Acylethanolamine Receptor Gpr119-Induced Activation of Gastrointestinal Mucosal Responses

(2010) Helen M. Cox et al.   Cell Metabolism

Paneth cells and innate mucosal immunity

(2010) André J Ouellette   CURRENT OPINION IN GASTROENTEROLOGY

TRP Channels in the Digestive System

(2010) Peter Holzer   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Homodimerization Is Essential for the Receptor for Advanced Glycation End Products (RAGE)-mediated Signal Transduction

(2010) Hongliang Zong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The cell biology of taste

(2010) Nirupa Chaudhari et al.   JOURNAL OF CELL BIOLOGY

Cytochrome P450-mediated metabolism in the human gut wall

(2010) Kirstin Thelen et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

The effects of glucagon-like peptide 2 on enteric neurons in intestinal inflammation

(2010) D. L. Sigalet et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Differential incretin effects of GIP and GLP-1 on gastric emptying, appetite, and insulin-glucose homeostasis

(2010) T. Edholm et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Review article: new receptor targets for medical therapy in irritable bowel syndrome

(2009) M. CAMILLERI   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Visceral afferents — Determinants and modulation of excitability

(2009) Michael J. Beyak   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

(2009) Charles Thomas et al.   Cell Metabolism

Ingestion of Diet Soda Before a Glucose Load Augments Glucagon-Like Peptide-1 Secretion

(2009) R. J. Brown et al.   DIABETES CARE

Essential oils and aromatic plants in animal feeding - a European perspective. A review.

(2009) C. Franz et al.   FLAVOUR AND FRAGRANCE JOURNAL

Glucagon-Like Peptide-2 Increases Intestinal Lipid Absorption and Chylomicron Production via CD36

(2009) Joanne Hsieh et al.   GASTROENTEROLOGY

TRPV1-expressing sensory fibres and IBS: links with immune function

(2009) P A Hughes et al.   GUT

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

Teduglutide, a novel mucosally active analog of glucagon-like peptide-2 (GLP-2) for the treatment of moderate to severe Crohnʼs disease

(2009) Alan L. Buchman et al.   INFLAMMATORY BOWEL DISEASES

Gastrointestinal satiety signals

(2009) O B Chaudhri et al.   INTERNATIONAL JOURNAL OF OBESITY

Plasticity of enteric nerve functions in the inflamed and postinflamed gut

(2009) g. m. mawe et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Receptor-mediated activation of gastric vagal afferents by glucagon-like peptide-1 in the rat

(2009) v. bucinskaite et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Inflammatory Bowel Disease

(2009) Clara Abraham et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ghrelin, des-acyl ghrelin and nesfatin-1 in gastric X/A-like cells: Role as regulators of food intake and body weight

(2009) Andreas Stengel et al.   PEPTIDES

TRPA1 regulates gastrointestinal motility through serotonin release from enterochromaffin cells

(2009) K. Nozawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Gut Feeling for Obesity: 7TM Sensors on Enteroendocrine Cells

(2008) Maja S. Engelstoft et al.   Cell Metabolism

Glucose Sensing in L Cells: A Primary Cell Study

(2008) Frank Reimann et al.   Cell Metabolism

Gpr40 Is Expressed in Enteroendocrine Cells and Mediates Free Fatty Acid Stimulation of Incretin Secretion

(2008) S. Edfalk et al.   DIABETES

A Role for Intestinal Endocrine Cell-Expressed G Protein-Coupled Receptor 119 in Glycemic Control by Enhancing Glucagon-Like Peptide-1 and Glucose-Dependent Insulinotropic Peptide Release

(2008) Zhi-Liang Chu et al.   ENDOCRINOLOGY

Induction of pro-inflammatory programs in enteroendocrine cells by the Toll-like receptor agonists flagellin and bacterial LPS

(2008) Silvia Selleri et al.   INTERNATIONAL IMMUNOLOGY

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

(2008) S. Vaishnava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucagon-like peptide-2 increases mesenteric blood flow in humans

(2008) Lasse Bremholm et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Functional differences between M cells and enterocytes in sampling luminal antigens

(2008) Jennelle M. Kyd et al.   VACCINE

Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family

(2008) B. Hagenbuch et al.   XENOBIOTICA

Peptide transporters and their roles in physiological processes and drug disposition

(2008) I. Rubio-Aliaga et al.   XENOBIOTICA

Inhibitors of advanced glycation end-products prevent loss of enteric neuronal nitric oxide synthase in diabetic rats

(2007) p. v. s. jeyabal et al.   NEUROGASTROENTEROLOGY AND MOTILITY