Epithelial delamination is protective during pharmaceutical-induced enteropathy
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Epithelial delamination is protective during pharmaceutical-induced enteropathy
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 116, Issue 34, Pages 16961-16970
Publisher
Proceedings of the National Academy of Sciences
Online
2019-08-08
DOI
10.1073/pnas.1902596116
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mechanisms of Damage to the Gastrointestinal Tract From Nonsteroidal Anti-Inflammatory Drugs
- (2018) Ingvar Bjarnason et al. GASTROENTEROLOGY
- IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A
- (2018) Hery Urra et al. NATURE CELL BIOLOGY
- How to determine the role of the microbiome in drug disposition
- (2018) Jordan E Bisanz et al. DRUG METABOLISM AND DISPOSITION
- Defective ATG16L1-mediated removal of IRE1α drives Crohn’s disease–like ileitis
- (2017) Markus Tschurtschenthaler et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Interhost dispersal alters microbiome assembly and can overwhelm host innate immunity in an experimental zebrafish model
- (2017) Adam R. Burns et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chemical transformation of xenobiotics by the human gut microbiota
- (2017) Nitzan Koppel et al. SCIENCE
- Epithelial cell extrusion: Pathways and pathologies
- (2017) Swapna Aravind Gudipaty et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Genomic dissection of conserved transcriptional regulation in intestinal epithelial cells
- (2017) Colin R. Lickwar et al. PLOS BIOLOGY
- Structural and Functional Analysis of the Allosteric Inhibition of IRE1α with ATP-Competitive Ligands
- (2016) Hannah C. Feldman et al. ACS Chemical Biology
- NOD1 and NOD2 signalling links ER stress with inflammation
- (2016) A. Marijke Keestra-Gounder et al. NATURE
- The microbial pharmacists within us: a metagenomic view of xenobiotic metabolism
- (2016) Peter Spanogiannopoulos et al. NATURE REVIEWS MICROBIOLOGY
- Identification of new MRP4 inhibitors from a library of FDA approved drugs using a high-throughput bioluminescence screen
- (2015) Leanna Cheung et al. BIOCHEMICAL PHARMACOLOGY
- Cell death at the intestinal epithelial front line
- (2015) Maria Eugenia Delgado et al. FEBS Journal
- Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage
- (2015) Denise N. Bronner et al. IMMUNITY
- A transgenic zebrafish model for monitoring xbp1 splicing and endoplasmic reticulum stress in vivo
- (2015) Junling Li et al. MECHANISMS OF DEVELOPMENT
- Epigenetic control of intestinal barrier function and inflammation in zebrafish
- (2015) Lindsay Marjoram et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ontogenetic Differences in Dietary Fat Influence Microbiota Assembly in the Zebrafish Gut
- (2015) Sandi Wong et al. mBio
- Role of the Breast Cancer Resistance Protein (BCRP/ABCG2) in Drug Transport—an Update
- (2014) Qingcheng Mao et al. AAPS Journal
- Allosteric Inhibition of the IRE1α RNase Preserves Cell Viability and Function during Endoplasmic Reticulum Stress
- (2014) Rajarshi Ghosh et al. CELL
- Role of the Microbiota in Immunity and Inflammation
- (2014) Yasmine Belkaid et al. CELL
- Microbial Determinants of Biochemical Individuality and Their Impact on Toxicology and Pharmacology
- (2014) Andrew D. Patterson et al. Cell Metabolism
- Current advances on ABC drug transporters in fish
- (2014) Till Luckenbach et al. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
- Molecularly defined unfolded protein response subclasses have distinct correlations with fatty liver disease in zebrafish
- (2014) A. M. Vacaru et al. Disease Models & Mechanisms
- Nonsteroidal Anti-inflammatory Drugs, Proton Pump Inhibitors, and Gastrointestinal Injury: Contrasting Interactions in the Stomach and Small Intestine
- (2014) Wojciech Marlicz et al. MAYO CLINIC PROCEEDINGS
- Characterization of Zebrafish Abcc4 as an Efflux Transporter of Organochlorine Pesticides
- (2014) Xing Lu et al. PLoS One
- Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome
- (2013) Corinne Ferrier Maurice et al. CELL
- Paneth cells as a site of origin for intestinal inflammation
- (2013) Timon E. Adolph et al. NATURE
- Predicting and Manipulating Cardiac Drug Inactivation by the Human Gut Bacterium Eggerthella lenta
- (2013) H. J. Haiser et al. SCIENCE
- Bacterial β-glucuronidase inhibition protects mice against enteropathy induced by indomethacin, ketoprofen or diclofenac: mode of action and pharmacokinetics
- (2013) Kyle S. Saitta et al. XENOBIOTICA
- Chemically Induced Intestinal Damage Models in Zebrafish Larvae
- (2013) Stefan H. Oehlers et al. Zebrafish
- Pharmacological brake-release of mRNA translation enhances cognitive memory
- (2013) Carmela Sidrauski et al. eLife
- Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections
- (2012) David M. Tobin et al. CELL
- Endoplasmic Reticulum Stress and Inflammation
- (2012) Timon-Eric Adolph et al. DIGESTIVE DISEASES
- Glafenine-induced intestinal injury in zebrafish is ameliorated by -opioid signaling via enhancement of Atf6-dependent cellular stress responses
- (2012) J. R. Goldsmith et al. Disease Models & Mechanisms
- Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors
- (2012) Likun Wang et al. Nature Chemical Biology
- The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule
- (2012) B. C. S. Cross et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Multiple NSAID-Induced Hits Injure the Small Intestine: Underlying Mechanisms and Novel Strategies
- (2012) Urs A. Boelsterli et al. TOXICOLOGICAL SCIENCES
- Toward a new age of cellular pharmacokinetics in drug discovery
- (2011) Fang Zhou et al. DRUG METABOLISM REVIEWS
- Carboxylesterase inhibitors
- (2011) M. Jason Hatfield et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Microbial Colonization Induces Dynamic Temporal and Spatial Patterns of NF-κB Activation in the Zebrafish Digestive Tract
- (2011) Michelle Kanther et al. GASTROENTEROLOGY
- Interactions Between the Host Innate Immune System and Microbes in Inflammatory Bowel Disease
- (2011) Clara Abraham et al. GASTROENTEROLOGY
- The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
- (2011) P. Walter et al. SCIENCE
- mpeg1 promoter transgenes direct macrophage-lineage expression in zebrafish
- (2010) F. Ellett et al. BLOOD
- Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma
- (2010) I. Papandreou et al. BLOOD
- Topographical distribution of antimicrobial genes in the zebrafish intestine
- (2010) Stefan H. Oehlers et al. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
- A chemical enterocolitis model in zebrafish larvae that is dependent on microbiota and responsive to pharmacological agents
- (2010) Stefan H. Oehlers et al. DEVELOPMENTAL DYNAMICS
- Live imaging of apoptotic cells in zebrafish
- (2010) Tjakko J. van Ham et al. FASEB JOURNAL
- Enzymatic Conversion of Odorants in Nasal Mucus Affects Olfactory Glomerular Activation Patterns and Odor Perception
- (2010) A. Nagashima et al. JOURNAL OF NEUROSCIENCE
- Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme
- (2010) B. D. Wallace et al. SCIENCE
- Small Molecule Screening in Zebrafish
- (2010) David S. Peal et al. Journal of Cardiovascular Translational Research
- Assaying autophagic activity in transgenic GFP-Lc3 and GFP-Gabarap zebrafish embryos
- (2009) Congcong He et al. Autophagy
- Identification of Inhibitors of ABCG2 by a Bioluminescence Imaging-Based High-Throughput Assay
- (2009) Y. Zhang et al. CANCER RESEARCH
- Multidrug efflux pumps: Substrate selection in ATP-binding cassette multidrug efflux pumps - first come, first served?
- (2009) Robert Ernst et al. FEBS Journal
- Differential susceptibility of P-glycoprotein deficient mice to colitis induction by environmental insults
- (2008) Elizabeth M. Staley et al. INFLAMMATORY BOWEL DISEASES
- Methods for generating and colonizing gnotobiotic zebrafish
- (2008) Linh N Pham et al. Nature Protocols
- Antioxidants reduce endoplasmic reticulum stress and improve protein secretion
- (2008) J. D. Malhotra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started