In vitro hepatic steatosis model based on gut–liver‐on‐a‐chip

Microfluidic oxygen sensor system as a tool to monitor the metabolism of mammalian cells

(2019) Frank Bunge et al.   SENSORS AND ACTUATORS B-CHEMICAL

Paracellular Pathway Enhancement of Metformin Hydrochloride via Molecular Dispersion in Span 60 Microparticles

(2019) Omar Y. Mady et al.   Frontiers in Pharmacology

Gut-liver on a chip towards an in vitro model of hepatic steatosis

(2018) Seung Yeon Lee et al.   BIOTECHNOLOGY AND BIOENGINEERING

Systemic and vascular inflammation in an in-vitro model of central obesity

(2018) Arti Ahluwalia et al.   PLoS One

Three-dimensional perfused human in vitro model of non-alcoholic fatty liver disease

(2017) Tomasz Kostrzewski et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Organ-on-a-Chip Technology for Reproducing Multiorgan Physiology

(2017) Seung Hwan Lee et al.   Advanced Healthcare Materials

A microfluidic optical platform for real-time monitoring of pH and oxygen in microfluidic bioreactors and organ-on-chip devices

(2016) Seyed Ali Mousavi Shaegh et al.   Biomicrofluidics

A pumpless multi-organ-on-a-chip (MOC) combined with a pharmacokinetic-pharmacodynamic (PK-PD) model

(2016) Hyuna Lee et al.   BIOTECHNOLOGY AND BIOENGINEERING

A microfluidics-based in vitro model of the gastrointestinal human–microbe interface

(2016) Pranjul Shah et al.   Nature Communications

Investigating Nonalcoholic Fatty Liver Disease in a Liver-on-a-Chip Microfluidic Device

(2016) Manuele Gori et al.   PLoS One

A microfluidic cell culture device (μFCCD) to culture epithelial cells with physiological and morphological properties that mimic those of the human intestine

(2015) Meiying Chi et al.   BIOMEDICAL MICRODEVICES

Gut–liver axis, nutrition, and non-alcoholic fatty liver disease

(2015) Irina A. Kirpich et al.   CLINICAL BIOCHEMISTRY

Bioreactor technologies to support liver function in vitro

(2014) Mohammad R. Ebrahimkhani et al.   ADVANCED DRUG DELIVERY REVIEWS

Metformin alleviates hepatosteatosis by restoring SIRT1-mediated autophagy induction via an AMP-activated protein kinase-independent pathway

(2014) Young Mi Song et al.   Autophagy

Activation of farnesoid X receptor (FXR) protects against fructose-induced liver steatosis via inflammatory inhibition and ADRP reduction

(2014) Xijun Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation

(2013) Hyun Jung Kim et al.   Integrative Biology

In Vitro and in Vivo Models of Non-Alcoholic Fatty Liver Disease (NAFLD)

(2013) Giridhar Kanuri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Microfluidic Device with 3-D Hydrogel Villi Scaffold to Simulate Intestinal Absorption

(2013) Si Hyeon Kim et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Microfabricated mammalian organ systems and their integration into models of whole animals and humans

(2013) Jong H. Sung et al.   LAB ON A CHIP

Microfabrication of human organs-on-chips

(2013) Dongeun Huh et al.   Nature Protocols

Learning from berberine: Treating chronic diseases through multiple targets

(2013) Jing Yao et al.   Science China-Life Sciences

Farnesoid X receptor targeting to treat nonalcoholic steatohepatitis

(2012) Luciano Adorini et al.   DRUG DISCOVERY TODAY

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow

(2012) Hyun Jung Kim et al.   LAB ON A CHIP

Omega-3 supplementation and non-alcoholic fatty liver disease: A systematic review and meta-analysis

(2011) Helen M. Parker et al.   JOURNAL OF HEPATOLOGY

Postprandial triglyceride-rich lipoproteins induce hepatic insulin resistance in HepG2 cells independently of their receptor-mediated cellular uptake

(2011) Tobias Tatarczyk et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

GLP-1 Analogs Reduce Hepatocyte Steatosis and Improve Survival by Enhancing the Unfolded Protein Response and Promoting Macroautophagy

(2011) Shvetank Sharma et al.   PLoS One

From 3D cell culture to organs-on-chips

(2011) Dongeun Huh et al.   TRENDS IN CELL BIOLOGY

A microfluidic device for a pharmacokinetic–pharmacodynamic (PK–PD) model on a chip

(2010) Jong Hwan Sung et al.   LAB ON A CHIP

Microscale 3-D hydrogel scaffold for biomimetic gastrointestinal (GI) tract model

(2010) Jong Hwan Sung et al.   LAB ON A CHIP

Intestinal lipid absorption

(2009) Jahangir Iqbal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Non-alcoholic fatty liver disease pathogenesis: The present and the future

(2009) S. Petta et al.   DIGESTIVE AND LIVER DISEASE

Effect of fluid flow-induced shear stress on human mesenchymal stem cells: Differential gene expression of IL1B and MAP3K8 in MAPK signaling

(2009) John R. Glossop et al.   GENE EXPRESSION PATTERNS

Differential effect of oleic and palmitic acid on lipid accumulation and apoptosis in cultured hepatocytes

(2009) Matteo Ricchi et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Analysis of Unstirred Water Layer in In Vitro Permeability Experiments

(2009) Timo Korjamo et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Pathogenesis of non-alcoholic fatty liver disease

(2009) J. K. Dowman et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Butyrate modulates oxidative stress in the colonic mucosa of healthy humans

(2008) Henrike M. Hamer et al.   CLINICAL NUTRITION

The lysosomal-mitochondrial axis in free fatty acid-induced hepatic lipotoxicity

(2008) ZhengZheng Li et al.   HEPATOLOGY

Biopharmaceutics Classification System: Validation and Learnings of an in Vitro Permeability Assay

(2008) Victoria E. Thiel-Demby et al.   MOLECULAR PHARMACEUTICS

Incorporation of 3T3-L1 Cells To Mimic Bioaccumulation in a Microscale Cell Culture Analog Device for Toxicity Studies

(2004) Kwanchanok Viravaidya et al.   BIOTECHNOLOGY PROGRESS