In Vitro and in Vivo Models of Non-Alcoholic Fatty Liver Disease (NAFLD)

Nonalcoholic Fatty Liver Disease in Humans Is Associated with Increased Plasma Endotoxin and Plasminogen Activator Inhibitor 1 Concentrations and with Fructose Intake

(2018) Sabine Thuy et al.   JOURNAL OF NUTRITION

A C. elegans model to study human metabolic regulation

(2013) Sarwar Hashmi et al.   Nutrition & Metabolism

Steatohepatitis in laboratory opossums exhibiting a high lipemic response to dietary cholesterol and fat

(2012) Jeannie Chan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Liver cholesterol: is it playing possum in NASH?

(2012) Geoffrey C. Farrell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Nutrition, Intestinal Permeability, and Blood Ethanol Levels Are Altered in Patients with Nonalcoholic Fatty Liver Disease (NAFLD)

(2012) Valentina Volynets et al.   DIGESTIVE DISEASES AND SCIENCES

The association between adipocytokines and biomarkers for nonalcoholic fatty liver disease-induced liver injury

(2012) Shira Zelber-Sagi et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

An Overview of Stress Response and Hypometabolic Strategies in Caenorhabditis elegans: Conserved and Contrasting Signals with the Mammalian System

(2012) Benjamin Lant et al.   International Journal of Biological Sciences

Association of nonalcoholic fatty liver disease with a single nucleotide polymorphism on the gene encoding leptin receptor

(2012) Menha Swellam et al.   IUBMB LIFE

High-fat, high-fructose diet induces hepatic iron overload via a hepcidin-independent mechanism prior to the onset of liver steatosis and insulin resistance in mice

(2012) Hiroyuki Tsuchiya et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Association between eating out of home and body weight

(2012) Ilana N Bezerra et al.   NUTRITION REVIEWS

Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

(2012) Yoshihisa Takahashi   WORLD JOURNAL OF GASTROENTEROLOGY

Melanocortin 4 Receptor–Deficient Mice as a Novel Mouse Model of Nonalcoholic Steatohepatitis

(2011) Michiko Itoh et al.   AMERICAN JOURNAL OF PATHOLOGY

Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance

(2011) Haihong Zong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition

(2011) Michael Charlton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Nonalcoholic fatty liver disease

(2011) Marcin Krawczyk et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

In Vitro Models for the Study of Non-Alcoholic Fatty Liver Disease

(2011) N. C. Chavez-Tapia et al.   CURRENT MEDICINAL CHEMISTRY

Kupffer cell depletion prevents but has no therapeutic effect on metabolic and inflammatory changes induced by a high-fat diet

(2011) Nicolas Lanthier et al.   FASEB JOURNAL

Human Fatty Liver Disease: Old Questions and New Insights

(2011) J. C. Cohen et al.   SCIENCE

Role of the Inducible Nitric Oxide Synthase in the Onset of Fructose-Induced Steatosis in Mice

(2010) Astrid Spruss et al.   ANTIOXIDANTS & REDOX SIGNALING

Use of three-dimensional spheroids of hepatocyte-derived reporter cells to study the effects of intracellular fat accumulation and subsequent cytokine exposure

(2010) Amol V. Janorkar et al.   BIOTECHNOLOGY AND BIOENGINEERING

Animal Models of Non-Alcoholic Steatohepatitis: Of Mice and Man

(2010) J.M. Schattenberg et al.   DIGESTIVE DISEASES

Tissue Engineering der Leber

(2010) H. C. Fiegel et al.   Handchirurgie Mikrochirurgie Plastische Chirurgie

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: distinct clinicopathologic meanings

(2010) Elizabeth M. Brunt et al.   HEPATOLOGY

Adiponectin and Heme Oxygenase-1 Suppress TLR4/MyD88-Independent Signaling in Rat Kupffer Cells and in Mice after Chronic Ethanol Exposure

(2010) P. Mandal et al.   JOURNAL OF IMMUNOLOGY

Elevated endotoxin levels in non-alcoholic fatty liver disease

(2010) Alison L Harte et al.   Journal of Inflammation-London

Role of tumor necrosis factor α (TNFα) in the onset of fructose-induced nonalcoholic fatty liver disease in mice

(2010) Giridhar Kanuri et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Fructose and metabolic diseases: New findings, new questions

(2010) Luc Tappy et al.   NUTRITION

High levels of dietary stearate promote adiposity and deteriorate hepatic insulin sensitivity

(2010) Sjoerd AA van den Berg et al.   Nutrition & Metabolism

Toll-like receptor 4 is involved in the development of fructose-induced hepatic steatosis in mice

(2009) Astrid Spruss et al.   HEPATOLOGY

Nutritional model of steatohepatitis and metabolic syndrome in the Ossabaw miniature swine

(2009) Lydia Lee et al.   HEPATOLOGY

Diet-induced hepatocellular carcinoma in genetically predisposed mice

(2009) A. E. Hill-Baskin et al.   HUMAN MOLECULAR GENETICS

Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet

(2009) Igor P. Pogribny et al.   JOURNAL OF HEPATOLOGY

Dietary fructose and intestinal barrier: potential risk factor in the pathogenesis of nonalcoholic fatty liver disease

(2009) Astrid Spruss et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Genetic differences in oxidative stress and inflammatory responses to diet-induced obesity do not alter liver fibrosis in mice

(2009) Wing-Kin Syn et al.   LIVER INTERNATIONAL

Evaluation of acoustic radiation force impulse elastography for fibrosis staging of chronic liver disease: a pilot study

(2009) Hirokazu Takahashi et al.   LIVER INTERNATIONAL

Effects of atherogenic diet on hepatic gene expression across mouse strains

(2009) Keith R. Shockley et al.   PHYSIOLOGICAL GENOMICS

The Transition from Fatty Liver to NASH Associates with SAMe Depletion in db/db Mice Fed a Methionine Choline-Deficient Diet

(2008) Matthew Wortham et al.   DIGESTIVE DISEASES AND SCIENCES

Effects of a Long-Term High-Fat Diet and Switching from a High-Fat to Low-Fat, Standard Diet on Hepatic Fat Accumulation in Sprague-Dawley Rats

(2008) Katsuhisa Omagari et al.   DIGESTIVE DISEASES AND SCIENCES

Non-alcoholic steatohepatitis and animal models: Understanding the human disease

(2008) Marta Varela-Rey et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

MCD-induced steatohepatitis is associated with hepatic adiponectin resistance and adipogenic transformation of hepatocytes

(2008) Claire Z. Larter et al.   JOURNAL OF HEPATOLOGY

Antibiotics protect against fructose-induced hepatic lipid accumulation in mice: Role of endotoxin

(2008) Ina Bergheim et al.   JOURNAL OF HEPATOLOGY

Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet

(2008) Mary E. Rinella et al.   JOURNAL OF LIPID RESEARCH

The establishment of a novel non-alcoholic steatohepatitis model accompanied with obesity and insulin resistance in mice

(2008) Wei-Na Cong et al.   LIFE SCIENCES

Interstrain differences in susceptibility to non-alcoholic steatohepatitis

(2007) Yuichi Yamazaki et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY