Three-dimensional perfused human in vitro model of non-alcoholic fatty liver disease

IL-6 pathway in the liver: From physiopathology to therapy

(2016) Dirk Schmidt-Arras et al.   JOURNAL OF HEPATOLOGY

A concise review of non-alcoholic fatty liver disease

(2015) Nwe Ni Than et al.   ATHEROSCLEROSIS

Nonalcoholic fatty liver disease

(2015) Timothy Hardy et al.   CURRENT OPINION IN GASTROENTEROLOGY

The application of engineered liver tissues for novel drug discovery

(2015) Christine Lin et al.   Expert Opinion on Drug Discovery

Organs-on-chips at the frontiers of drug discovery

(2015) Eric W. Esch et al.   NATURE REVIEWS DRUG DISCOVERY

Strategies, models and biomarkers in experimental non-alcoholic fatty liver disease research

(2015) Joost Willebrords et al.   PROGRESS IN LIPID RESEARCH

Nonalcoholic Steatohepatitis: A Search for Factual Animal Models

(2015) Sheila Cristina L. Sanches et al.   Biomed Research International

Role of Macrophage Migration Inhibitory Factor in Obesity, Insulin Resistance, Type 2 Diabetes, and Associated Hepatic Co-Morbidities: A Comprehensive Review of Human and Rodent Studies

(2015) Martine C. Morrison et al.   Frontiers in Immunology

Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes

(2015) Wasco Wruck et al.   Scientific Data

Bioreactor technologies to support liver function in vitro

(2014) Mohammad R. Ebrahimkhani et al.   ADVANCED DRUG DELIVERY REVIEWS

Focus on emerging drugs for the treatment of patients with non-alcoholic fatty liver disease

(2014) Alessandro Federico   WORLD JOURNAL OF GASTROENTEROLOGY

Noninvasive biomarkers in non-alcoholic fatty liver disease: Current status and a glimpse of the future

(2014) Emer Fitzpatrick   WORLD JOURNAL OF GASTROENTEROLOGY

Morphological behaviour and metabolic capacity of cryopreserved human primary hepatocytes cultivated in a perfused multiwell device

(2014) Aurelie Vivares et al.   XENOBIOTICA

Metformin prevents hepatic steatosis by regulating the expression of adipose differentiation-related protein

(2013) FANG LIU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Identification of serum insulin-like growth factor binding protein 1 as diagnostic biomarker for early-stage alcohol-induced liver disease

(2013) Heng-Hong Li et al.   Journal of Translational Medicine

The genetics of NAFLD

(2013) Quentin M. Anstee et al.   Nature Reviews Gastroenterology & Hepatology

Genetic Inactivation of Pyruvate Dehydrogenase Kinases Improves Hepatic Insulin Resistance Induced Diabetes

(2013) Rongya Tao et al.   PLoS One

Effect of intracellular lipid accumulation in a new model of non-alcoholic fatty liver disease

(2012) Norberto C Chavez-Tapia et al.   BMC GASTROENTEROLOGY

Increased Hepatic Synthesis and Dysregulation of Cholesterol Metabolism Is Associated with the Severity of Nonalcoholic Fatty Liver Disease

(2012) Hae-Ki Min et al.   Cell Metabolism

CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease

(2012) Tung-Ming Leung et al.   JOURNAL OF HEPATOLOGY

Liv.52 up-regulates cellular antioxidants and increase glucose uptake to circumvent oleic acid induced hepatic steatosis in HepG2 cells

(2012) Satyakumar Vidyashankar et al.   PHYTOMEDICINE

Role of cytokines and chemokines in non-alcoholic fatty liver disease

(2012) Vincent Braunersreuther   WORLD JOURNAL OF GASTROENTEROLOGY

A novel 3D liver organoid system for elucidation of hepatic glucose metabolism

(2011) Yanhua Lu et al.   BIOTECHNOLOGY AND BIOENGINEERING

Analysis of Global and Absorption, Distribution, Metabolism, and Elimination Gene Expression in the Progressive Stages of Human Nonalcoholic Fatty Liver Disease

(2011) A. D. Lake et al.   DRUG METABOLISM AND DISPOSITION

From 3D cell culture to organs-on-chips

(2011) Dongeun Huh et al.   TRENDS IN CELL BIOLOGY

Increased expression of cytochrome P450 2E1 in nonalcoholic fatty liver disease: Mechanisms and pathophysiological role

(2011) J. Aubert et al.   Clinics and Research in Hepatology and Gastroenterology

Use of three-dimensional spheroids of hepatocyte-derived reporter cells to study the effects of intracellular fat accumulation and subsequent cytokine exposure

(2010) Amol V. Janorkar et al.   BIOTECHNOLOGY AND BIOENGINEERING

Macrophage migration inhibitory factor expression and MIF gene −173 G/C polymorphism in nonalcoholic fatty liver disease

(2010) Murat Akyildiz et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Dissociation Between Intrahepatic Triglyceride Content and Insulin Resistance in Familial Hypobetalipoproteinemia

(2010) Anastassia Amaro et al.   GASTROENTEROLOGY

Networks Inferred from Biochemical Data Reveal Profound Differences in Toll-like Receptor and Inflammatory Signaling between Normal and Transformed Hepatocytes

(2010) Leonidas G. Alexopoulos et al.   MOLECULAR & CELLULAR PROTEOMICS

Non-alcoholic fatty liver disease: the hepatic consequence of obesity and the metabolic syndrome

(2010) J. Bernadette Moore   PROCEEDINGS OF THE NUTRITION SOCIETY

Liver tissue engineering in the evaluation of drug safety

(2009) Ajit Dash et al.   Expert Opinion on Drug Metabolism & Toxicology

Perfused multiwell plate for 3D liver tissue engineering

(2009) Karel Domansky et al.   LAB ON A CHIP

Randomized, Placebo-Controlled Trial of Pioglitazone in Nondiabetic Subjects With Nonalcoholic Steatohepatitis

(2008) Guruprasad P. Aithal et al.   GASTROENTEROLOGY