Enhanced immune memory through a constant Photothermal-Metabolism regulation for Cancer Prevention and Treatment

Targeting photodynamic and photothermal therapy to the endoplasmic reticulum enhances immunogenic cancer cell death

(2019) Wei Li et al.   Nature Communications

Near-Infrared II Phototherapy Induces Deep Tissue Immunogenic Cell Death and Potentiates Cancer Immunotherapy

(2019) Yinchu Ma et al.   ACS Nano

PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity

(2019) Martin W. LaFleur et al.   NATURE IMMUNOLOGY

Immunotherapy: Artificial Engineered Natural Killer Cells Combined with Antiheat Endurance as a Powerful Strategy for Enhancing Photothermal‐Immunotherapy Efficiency of Solid Tumors (Small 42/2019)

(2019) Da Zhang et al.   Small

Laser Immunotherapy in Combination with Perdurable PD-1 Blocking for Treatment of Metastatic Tumor

(2018) Lihua Luo et al.   ACS Nano

Etomoxir Actions on Regulatory and Memory T Cells Are Independent of Cpt1a-Mediated Fatty Acid Oxidation

(2018) Brenda Raud et al.   Cell Metabolism

Fatty acid metabolism in CD8+ T cell memory: Challenging current concepts

(2018) Brenda Raud et al.   IMMUNOLOGICAL REVIEWS

Therapeutic cancer vaccines: From initial findings to prospects

(2018) Qian Song et al.   IMMUNOLOGY LETTERS

Sustained release of anti-PD-1 peptide for perdurable immunotherapy together with photothermal ablation against primary and distant tumors

(2018) Lihua Luo et al.   JOURNAL OF CONTROLLED RELEASE

Potential of memory T cells in bridging preoperative chemoradiation and immunotherapy in rectal cancer

(2018) Sven de Mey et al.   RADIOTHERAPY AND ONCOLOGY

Metformin exerts antitumor activity via induction of multiple death pathways in tumor cells and activation of a protective immune response

(2018) Felipe V. Pereira et al.   Oncotarget

Lipid-Based Particles: Versatile Delivery Systems for Mucosal Vaccination against Infection

(2018) Blaise Corthésy et al.   Frontiers in Immunology

Diverse Roles of Mitochondria in Immune Responses: Novel Insights Into Immuno-Metabolism

(2018) Anusha Angajala et al.   Frontiers in Immunology

Autoimmune sialadenitis is associated with the upregulation of chemokine/chemokine receptor pairs in T cell-specific TRAF6-deficient mice

(2018) Kaori Noguchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ERADicate Tumor Progression with Metformin

(2018) Lena-Sophie Dreher et al.   MOLECULAR CELL

Fatty Acid Oxidation in Macrophages and T Cells: Time for Reassessment?

(2018) Jan Van den Bossche et al.   Cell Metabolism

Transcription Factor IRF4 Promotes CD8 + T Cell Exhaustion and Limits the Development of Memory-like T Cells during Chronic Infection

(2017) Kevin Man et al.   IMMUNITY

Early Inhibition of Fatty Acid Synthesis Reduces Generation of Memory Precursor Effector T Cells in Chronic Infection

(2017) Samad A. Ibitokou et al.   JOURNAL OF IMMUNOLOGY

Effector CD8 T cells dedifferentiate into long-lived memory cells

(2017) Ben Youngblood et al.   NATURE

AMPK: guardian of metabolism and mitochondrial homeostasis

(2017) Sébastien Herzig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cervical Cancer: Prevention and Early Detection

(2017) Theresa A. Kessler   Seminars in Oncology Nursing

T Cell Fate at the Single-Cell Level

(2016) Veit R. Buchholz et al.   Annual Review of Immunology

Mitochondrial Networking in T Cell Memory

(2016) Marc Liesa et al.   CELL

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming

(2016) Michael D. Buck et al.   CELL

High antigen levels induce an exhausted phenotype in a chronic infection without impairing T cell expansion and survival

(2016) Daniel T. Utzschneider et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tethered IL-15 augments antitumor activity and promotes a stem-cell memory subset in tumor-specific T cells

(2016) Lenka V. Hurton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fatty acid metabolic reprogramming via mTOR-mediated inductions of PPARγ directs early activation of T cells

(2016) Mulki Angela et al.   Nature Communications

Efficacy of PD-1 Blockade Is Potentiated by Metformin-Induced Reduction of Tumor Hypoxia

(2016) Nicole E. Scharping et al.   Cancer Immunology Research

SnapShot: T Cell Exhaustion

(2015) Kristen E. Pauken et al.   CELL

Immune-mediated antitumor effect by type 2 diabetes drug, metformin

(2015) Shingo Eikawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting T cell metabolism for therapy

(2015) David O'Sullivan et al.   TRENDS IN IMMUNOLOGY

Combinatorial Photothermal and Immuno Cancer Therapy Using Chitosan-Coated Hollow Copper Sulfide Nanoparticles

(2014) Liangran Guo et al.   ACS Nano

Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development

(2014) David O’Sullivan et al.   IMMUNITY

AMPK in Lymphocyte Metabolism and Function

(2014) Fabienne Andris et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Differential Kinetics of Antigen Dependency of CD4+ and CD8+ T Cells

(2014) H. Rabenstein et al.   JOURNAL OF IMMUNOLOGY

Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

(2013) Chih-Hao Chang et al.   CELL

AMPKα1: A glucose sensor that controls CD8 T-cell memory

(2013) Julia Rolf et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Preexisting High Frequencies of Memory CD8+ T Cells Favor Rapid Memory Differentiation and Preservation of Proliferative Potential upon Boosting

(2013) Kathryn A. Fraser et al.   IMMUNITY

Whole tumor antigen vaccines

(2010) Cheryl Lai-Lai Chiang et al.   SEMINARS IN IMMUNOLOGY

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

(2009) Erika L. Pearce et al.   NATURE

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE