Amygdala circuit substrates for stress adaptation and adversity

Endocannabinoid Signaling Collapse Mediates Stress-Induced Amygdalo-Cortical Strengthening

(2020) David J. Marcus et al.   NEURON

Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect

(2020) Guilin Pi et al.   Nature Communications

mRNA and microRNA Profiles in the Amygdala Are Relevant to Susceptibility and Resilience to Psychological Stress Induced in Mice

(2020) Jinyan Sun et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Brain control of humoral immune responses amenable to behavioural modulation

(2020) Xu Zhang et al.   NATURE

Encoding of contextual fear memory in hippocampal–amygdala circuit

(2020) Woong Bin Kim et al.   Nature Communications

Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety

(2020) Wei-Zhu Liu et al.   Nature Communications

Traumatic Stress Induces Prolonged Aggression Increase through Synaptic Potentiation in the Medial Amygdala Circuits

(2020) Jacob Nordman et al.   eNeuro

Neuroinflammation induces anxiety- and depressive-like behavior by modulating neuronal plasticity in the basolateral amygdala

(2020) Zhi-Heng Zheng et al.   BRAIN BEHAVIOR AND IMMUNITY

Cannabinoid CB1 receptors in the amygdalar cholecystokinin glutamatergic afferents to nucleus accumbens modulate depressive-like behavior

(2019) Chen-Jie Shen et al.   NATURE MEDICINE

microRNA and mRNA profiles in the amygdala are associated with stress-induced depression and resilience in juvenile mice

(2019) Mengmeng Shen et al.   PSYCHOPHARMACOLOGY

Divergent medial amygdala projections regulate approach–avoidance conflict behavior

(2019) Samara M. Miller et al.   NATURE NEUROSCIENCE

Single-Prolonged Stress Impairs Prefrontal Cortex Control of Amygdala and Striatum in Rats

(2019) Veronica M. Piggott et al.   Frontiers in Behavioral Neuroscience

Role of the Bed Nucleus of the Stria Terminalis in PTSD: Insights From Preclinical Models

(2019) Olivia W. Miles et al.   Frontiers in Behavioral Neuroscience

microRNA and mRNA profiles in the amygdala are relevant to fear memory induced by physical or psychological stress

(2019) Yan Sun et al.   JOURNAL OF NEUROPHYSIOLOGY

A Discrete Dorsal Raphe to Basal Amygdala 5-HT Circuit Calibrates Aversive Memory

(2019) Ayesha Sengupta et al.   NEURON

A neural circuit for comorbid depressive symptoms in chronic pain

(2019) Wenjie Zhou et al.   NATURE NEUROSCIENCE

A Critical Role of Basolateral Amygdala to Nucleus Accumbens Projection in Sleep Regulation of Reward Seeking

(2019) Yao Wang et al.   BIOLOGICAL PSYCHIATRY

Amygdalar corticotropin-releasing factor mediates stress-induced anxiety

(2019) Ana Paula Ventura-Silva et al.   BRAIN RESEARCH

Moderate maternal separation mitigates the altered synaptic transmission and neuronal activation in amygdala by chronic stress in adult mice

(2019) Xia Qin et al.   Molecular Brain

Amygdala-Based Altered miRNome and Epigenetic Contribution of miR-128-3p in Conferring Susceptibility to Depression-Like Behavior via Wnt Signaling

(2019) Bhaskar Roy et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Role of TLR4 in the Modulation of Central Amygdala GABA Transmission by CRF Following Restraint Stress

(2018) F P Varodayan et al.   ALCOHOL AND ALCOHOLISM

Repeated social stress leads to contrasting patterns of structural plasticity in the amygdala and hippocampus

(2018) D. Patel et al.   BEHAVIOURAL BRAIN RESEARCH

Amygdala Inhibitory Circuits Regulate Associative Fear Conditioning

(2018) Sabine Krabbe et al.   BIOLOGICAL PSYCHIATRY

Chronic stress remodels synapses in an amygdala circuit-specific manner

(2018) Jun-Yu Zhang et al.   BIOLOGICAL PSYCHIATRY

Reduced resting-state functional connectivity of the basolateral amygdala to the medial prefrontal cortex in preweaning rats exposed to chronic early-life stress

(2018) Angela Guadagno et al.   Brain Structure & Function

New perspectives on central amygdala function

(2018) Jonathan P Fadok et al.   CURRENT OPINION IN NEUROBIOLOGY

A central extended amygdala circuit that modulates anxiety

(2018) Sandra Ahrens et al.   JOURNAL OF NEUROSCIENCE

MicroRNA-34 Contributes to the Stress-related Behavior and Affects 5-HT Prefrontal/GABA Amygdalar System through Regulation of Corticotropin-releasing Factor Receptor 1

(2018) Diego Andolina et al.   MOLECULAR NEUROBIOLOGY

Identification of a novel gene regulating amygdala-mediated fear extinction

(2018) Ozge Gunduz-Cinar et al.   MOLECULAR PSYCHIATRY

Amygdala Functional and Structural Connectivity Predicts Individual Risk Tolerance

(2018) Wi Hoon Jung et al.   NEURON

Anxiety Cells in a Hippocampal-Hypothalamic Circuit

(2018) Jessica C. Jimenez et al.   NEURON

Chronic stress dysregulates amygdalar output to the prefrontal cortex

(2018) Emily G. Lowery-Gionta et al.   NEUROPHARMACOLOGY

Anteroventral bed nuclei of the stria terminalis neurocircuitry: Towards an integration of HPA axis modulation with coping behaviors - Curt Richter Award Paper 2017

(2018) Jason J. Radley et al.   PSYCHONEUROENDOCRINOLOGY

Mechanisms of Stress-induced Visceral Pain

(2018) Beverley Greenwood-Van Meerveld et al.   Journal of Neurogastroenterology and Motility

Amygdala hyper-connectivity in a mouse model of unpredictable early life stress

(2018) Frances K. Johnson et al.   Translational Psychiatry

Effects of Peripheral Immune Challenge on In Vivo Firing of Basolateral Amygdala Neurons in Adult Male Rats

(2018) Soumyabrata Munshi et al.   NEUROSCIENCE

Chronic stress causes projection-specific adaptation of amygdala neurons via SK channel downregulation

(2018) Wen-Hua Zhang et al.   BIOLOGICAL PSYCHIATRY

A CORTICOTROPIN RELEASING FACTOR NETWORK IN THE EXTENDED AMYGDALA FOR ANXIETY

(2018) Matthew B. Pomrenze et al.   JOURNAL OF NEUROSCIENCE

Prefrontal–bed nucleus circuit modulation of a passive coping response set

(2018) Shane B. Johnson et al.   JOURNAL OF NEUROSCIENCE

Epigenetics at the crossroads between genes, environment and resilience in anxiety disorders

(2017) M. A. Schiele et al.   GENES BRAIN AND BEHAVIOR

Manipulating fear associations via optogenetic modulation of amygdala inputs to prefrontal cortex

(2017) Oded Klavir et al.   NATURE NEUROSCIENCE

Amygdala inputs to prefrontal cortex guide behavior amid conflicting cues of reward and punishment

(2017) Anthony Burgos-Robles et al.   NATURE NEUROSCIENCE

Sex Differences in Trauma-Related Psychopathology: a Critical Review of Neuroimaging Literature (2014–2017)

(2017) Liat Helpman et al.   Current Psychiatry Reports

Basolateral amygdala and stress-induced hyperexcitability affect motivated behaviors and addiction

(2017) B M Sharp   Translational Psychiatry

Resting-State Neuroimaging Studies: A New Way of Identifying Differences and Similarities among the Anxiety Disorders?

(2017) Andrew Peterson et al.   CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE

Stress-induced remodeling of hippocampal CA3 pyramidal neurons

(2016) Bruce S. McEwen   BRAIN RESEARCH

Distinct Hippocampal Pathways Mediate Dissociable Roles of Context in Memory Retrieval

(2016) Chun Xu et al.   CELL

Defining biotypes for depression and anxiety based on large-scale circuit dysfunction: a theoretical review of the evidence and future directions for clinical translation

(2016) Leanne M Williams   DEPRESSION AND ANXIETY

Functional Heterogeneity in the Bed Nucleus of the Stria Terminalis

(2016) N. Z. Gungor et al.   JOURNAL OF NEUROSCIENCE

Overshadowed by the amygdala: the bed nucleus of the stria terminalis emerges as key to psychiatric disorders

(2016) M A Lebow et al.   MOLECULAR PSYCHIATRY

Antagonistic negative and positive neurons of the basolateral amygdala

(2016) Joshua Kim et al.   NATURE NEUROSCIENCE

Impairment of decision making and disruption of synchrony between basolateral amygdala and anterior cingulate cortex in the maternally separated rat

(2016) Bing Cao et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Divergent Routing of Positive and Negative Information from the Amygdala during Memory Retrieval

(2016) Anna Beyeler et al.   NEURON

Stress increases GABAergic neurotransmission in CRF neurons of the central amygdala and bed nucleus stria terminalis

(2016) John G. Partridge et al.   NEUROPHARMACOLOGY

Bidirectional modulation of anxiety-related and social behaviors by amygdala projections to the medial prefrontal cortex

(2016) A.C. Felix-Ortiz et al.   NEUROSCIENCE

Opposite monosynaptic scaling of BLP–vCA1 inputs governs hopefulness- and helplessness-modulated spatial learning and memory

(2016) Ying Yang et al.   Nature Communications

Sex-specific neural circuits of emotion regulation in the centromedial amygdala

(2016) Yan Wu et al.   Scientific Reports

Amygdalar MicroRNA-15a Is Essential for Coping with Chronic Stress

(2016) Naama Volk et al.   Cell Reports

Identifying Predictors, Moderators, and Mediators of Antidepressant Response in Major Depressive Disorder: Neuroimaging Approaches

(2015) Mary L. Phillips et al.   AMERICAN JOURNAL OF PSYCHIATRY

The Central Amygdala as an Integrative Hub for Anxiety and Alcohol Use Disorders

(2015) Nicholas W. Gilpin et al.   BIOLOGICAL PSYCHIATRY

Behavioral Problems After Early Life Stress: Contributions of the Hippocampus and Amygdala

(2015) Jamie L. Hanson et al.   BIOLOGICAL PSYCHIATRY

Common and disorder-specific neural responses to emotional faces in generalised anxiety, social anxiety and panic disorders

(2015) Gregory A. Fonzo et al.   BRITISH JOURNAL OF PSYCHIATRY

From circuits to behaviour in the amygdala

(2015) Patricia H. Janak et al.   NATURE

Basomedial amygdala mediates top-down control of anxiety and fear

(2015) Avishek Adhikari et al.   NATURE

Resolving the neural circuits of anxiety

(2015) Gwendolyn G Calhoon et al.   NATURE NEUROSCIENCE

Neighborhood matters: divergent patterns of stress-induced plasticity across the brain

(2015) Sumantra Chattarji et al.   NATURE NEUROSCIENCE

CRH Engagement of the Locus Coeruleus Noradrenergic System Mediates Stress-Induced Anxiety

(2015) Jordan G. McCall et al.   NEURON

Sensory Inputs to Intercalated Cells Provide Fear-Learning Modulated Inhibition to the Basolateral Amygdala

(2015) Douglas Asede et al.   NEURON

A Neural Biomarker of Psychological Vulnerability to Future Life Stress

(2015) Johnna R. Swartz et al.   NEURON

Cannabinoids and Glucocorticoids in the Basolateral Amygdala Modulate Hippocampal–Accumbens Plasticity After Stress

(2015) Amir Segev et al.   NEUROPSYCHOPHARMACOLOGY

Stress and Fear Extinction

(2015) Stephen Maren et al.   NEUROPSYCHOPHARMACOLOGY

The Dissociative Subtype of Posttraumatic Stress Disorder: Unique Resting-State Functional Connectivity of Basolateral and Centromedial Amygdala Complexes

(2015) Andrew A Nicholson et al.   NEUROPSYCHOPHARMACOLOGY

Stress Effects on Neuronal Structure: Hippocampus, Amygdala and Prefrontal Cortex

(2015) Bruce S McEwen et al.   NEUROPSYCHOPHARMACOLOGY

FAAH genetic variation enhances fronto-amygdala function in mouse and human

(2015) Iva Dincheva et al.   Nature Communications

Fear learning circuitry is biased toward generalization of fear associations in posttraumatic stress disorder

(2015) R A Morey et al.   Translational Psychiatry

Prefrontal inputs to the amygdala instruct fear extinction memory formation

(2015) O. Bukalo et al.   Science Advances

Restraint Stress Alters Nociceptin/Orphanin FQ and CRF Systems in the Rat Central Amygdala: Significance for Anxiety-Like Behaviors

(2014) R. Ciccocioppo et al.   JOURNAL OF NEUROSCIENCE

Functional Properties and Projections of Neurons in the Medial Amygdala

(2014) S. Keshavarzi et al.   JOURNAL OF NEUROSCIENCE

Encoding of fear learning and memory in distributed neuronal circuits

(2014) Cyril Herry et al.   NATURE NEUROSCIENCE

Long-Range Connectivity Defines Behavioral Specificity of Amygdala Neurons

(2014) Verena Senn et al.   NEURON

Amygdala Microcircuits Controlling Learned Fear

(2014) Sevil Duvarci et al.   NEURON

Glutamatergic mechanisms associated with stress-induced amygdala excitability and anxiety-related behavior

(2014) Sophie Masneuf et al.   NEUROPHARMACOLOGY

Real-Time fMRI Neurofeedback Training of Amygdala Activity in Patients with Major Depressive Disorder

(2014) Kymberly D. Young et al.   PLoS One

Maternal Separation Enhances Conditioned Fear and Decreases the mRNA Levels of the Neurotensin Receptor 1 Gene with Hypermethylation of This Gene in the Rat Amygdala

(2014) Hiroyuki Toda et al.   PLoS One

Fear extinction deficits following acute stress associate with increased spine density and dendritic retraction in basolateral amygdala neurons

(2013) Mouna Maroun et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The impact of anxiety upon cognition: perspectives from human threat of shock studies

(2013) Oliver J. Robinson et al.   Frontiers in Human Neuroscience

The influence of puberty on subcortical brain development

(2013) Anne-Lise Goddings et al.   NEUROIMAGE

BLA to vHPC Inputs Modulate Anxiety-Related Behaviors

(2013) Ada C. Felix-Ortiz et al.   NEURON

Cannabinoid Receptor Activation Prevents the Effects of Chronic Mild Stress on Emotional Learning and LTP in a Rat Model of Depression

(2013) Amir Segev et al.   NEUROPSYCHOPHARMACOLOGY

Childhood maltreatment is associated with altered fear circuitry and increased internalizing symptoms by late adolescence

(2013) R. J. Herringa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early developmental emergence of human amygdala-prefrontal connectivity after maternal deprivation

(2013) D. G. Gee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stress and trauma: BDNF control of dendritic-spine formation and regression

(2013) M.R. Bennett et al.   PROGRESS IN NEUROBIOLOGY

Epigenomic Mechanisms of Early Adversity and HPA Dysfunction: Considerations for PTSD Research

(2013) Patrick O. McGowan   Frontiers in Psychiatry

Impaired prefrontal–amygdala effective connectivity is responsible for the dysfunction of emotion process in major depressive disorder: A dynamic causal modeling study on MEG

(2012) Qing Lu et al.   NEUROSCIENCE LETTERS

Chronic stress induces changes in the structure of interneurons and in the expression of molecules related to neuronal structural plasticity and inhibitory neurotransmission in the amygdala of adult mice

(2011) Javier Gilabert-Juan et al.   EXPERIMENTAL NEUROLOGY

Stereological analysis of the rat and monkey amygdala

(2011) Loïc J. Chareyron et al.   JOURNAL OF COMPARATIVE NEUROLOGY

The adaptive threat bias in anxiety: Amygdala–dorsomedial prefrontal cortex coupling and aversive amplification

(2011) Oliver J. Robinson et al.   NEUROIMAGE

Genetic Sensitivity to the Environment: The Case of the Serotonin Transporter Gene and Its Implications for Studying Complex Diseases and Traits

(2010) Avshalom Caspi et al.   AMERICAN JOURNAL OF PSYCHIATRY

Failure of Anterior Cingulate Activation and Connectivity With the Amygdala During Implicit Regulation of Emotional Processing in Generalized Anxiety Disorder

(2010) Amit Etkin et al.   AMERICAN JOURNAL OF PSYCHIATRY

The Role of the Medial and Central Amygdala in Stress-Induced Suppression of Pulsatile LH Secretion in Female Rats

(2010) Yuanshao Lin et al.   ENDOCRINOLOGY

Strain Differences in Stress Responsivity Are Associated with Divergent Amygdala Gene Expression and Glutamate-Mediated Neuronal Excitability

(2010) K. Mozhui et al.   JOURNAL OF NEUROSCIENCE

Neuroimaging in social anxiety disorder: A systematic review of the literature

(2010) Maria Cecilia Freitas-Ferrari et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Diminished Neural Processing of Aversive and Rewarding Stimuli During Selective Serotonin Reuptake Inhibitor Treatment

(2009) Ciara McCabe et al.   BIOLOGICAL PSYCHIATRY

Stress, memory and the amygdala

(2009) Benno Roozendaal et al.   NATURE REVIEWS NEUROSCIENCE

Neural regulation of endocrine and autonomic stress responses

(2009) Yvonne M. Ulrich-Lai et al.   NATURE REVIEWS NEUROSCIENCE

Addiction related alteration in resting-state brain connectivity

(2009) Ning Ma et al.   NEUROIMAGE

Evidence of biologic epistasis between BDNF and SLC6A4 and implications for depression

(2008) L Pezawas et al.   MOLECULAR PSYCHIATRY

Variation in Mouse Basolateral Amygdala Volume is Associated With Differences in Stress Reactivity and Fear Learning

(2008) Rebecca J Yang et al.   NEUROPSYCHOPHARMACOLOGY

Stress-induced prefrontal reorganization and executive dysfunction in rodents

(2008) Andrew Holmes et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Neonatal isolation stress alters bidirectional long-term synaptic plasticity in amygdalo-hippocampal synapses in freely behaving adult rats

(2007) J. Harry Blaise et al.   BRAIN RESEARCH

Repeated stress alters dendritic spine morphology in the rat medial prefrontal cortex

(2007) Jason J. Radley et al.   JOURNAL OF COMPARATIVE NEUROLOGY