Mechanisms of Stress-induced Visceral Pain

Amygdala-mediated mechanisms regulate visceral hypersensitivity in adult females following early life stress

(2017) Dawn K. Prusator et al.   PAIN

Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features, and Rome IV

(2016) Douglas A. Drossman   GASTROENTEROLOGY

Bowel Disorders

(2016) Brian E. Lacy et al.   GASTROENTEROLOGY

The impact of abuse and mood on bowel symptoms and health-related quality of life in irritable bowel syndrome (IBS)

(2016) N. Kanuri et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Sex differences in stress-induced visceral hypersensitivity following early life adversity: a two hit model

(2016) D. K. Prusator et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Neurobiology of early life stress and visceral pain: translational relevance from animal models to patient care

(2016) D. K. Prusator et al.   NEUROGASTROENTEROLOGY AND MOTILITY

The Role of Visceral Hypersensitivity in Irritable Bowel Syndrome: Pharmacological Targets and Novel Treatments

(2016) Mohammad H Farzaei et al.   Journal of Neurogastroenterology and Motility

Sex-related differences in pain behaviors following three early life stress paradigms

(2016) Dawn K. Prusator et al.   Biology of Sex Differences

Animal models of gastrointestinal and liver diseases. Animal models of visceral pain: pathophysiology, translational relevance, and challenges

(2015) Beverley Greenwood-Van Meerveld et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Epigenetic Regulation of Genes That Modulate Chronic Stress-Induced Visceral Pain in the Peripheral Nervous System

(2015) Shuangsong Hong et al.   GASTROENTEROLOGY

MicroRNA 29 Targets Nuclear Factor-κB–Repressing Factor and Claudin 1 to Increase Intestinal Permeability

(2015) QiQi Zhou et al.   GASTROENTEROLOGY

The role of mast cells in functional GI disorders

(2015) Mira M Wouters et al.   GUT

The joint power of sex and stress to modulate brain-gut-microbiota axis and intestinal barrier homeostasis: implications for irritable bowel syndrome

(2015) M. Pigrau et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Increased attentional network functioning related to symptom severity measures in females with irritable bowel syndrome

(2015) C. S. Hubbard et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Estradiol modulates visceral hyperalgesia by increasing thoracolumbar spinal GluN2B subunit activity in female rats

(2015) Y. Ji et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Early-life stress-induced visceral hypersensitivity and anxiety behavior is reversed by histone deacetylase inhibition

(2015) R. D. Moloney et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Knockdown of steroid receptors in the central nucleus of the amygdala induces heightened pain behaviors in the rat

(2015) Anthony C. Johnson et al.   NEUROPHARMACOLOGY

Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders

(2015) John R. Kelly et al.   Frontiers in Cellular Neuroscience

Role of MicroRNA in Visceral Pain

(2015) Jian Zhang et al.   Journal of Neurogastroenterology and Motility

Knockdown of corticotropin-releasing factor in the central amygdala reverses persistent viscerosomatic hyperalgesia

(2015) A C Johnson et al.   Translational Psychiatry

Epigenetic upregulation of metabotropic glutamate receptor 2 in the spinal cord attenuates oestrogen-induced visceral hypersensitivity

(2014) Dong-Yuan Cao et al.   GUT

Epigenetic modulation of chronic anxiety and pain by histone deacetylation

(2014) L Tran et al.   MOLECULAR PSYCHIATRY

Gender specific effects of neonatal limited nesting on viscerosomatic sensitivity and anxiety-like behavior in adult rats

(2014) D. K. Prusator et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Acute estrogen surge enhances inflammatory nociception without altering spinal Fos expression

(2014) Andrew Ralya et al.   NEUROSCIENCE LETTERS

Sex hormones in the modulation of irritable bowel syndrome

(2014) Agata Mulak   WORLD JOURNAL OF GASTROENTEROLOGY

Gender-related differences in irritable bowel syndrome: Potential mechanisms of sex hormones

(2014) Mathieu Meleine   WORLD JOURNAL OF GASTROENTEROLOGY

ASSOCIATION OF MENTAL HEALTH PROBLEMS WITH GASTROINTESTINAL DISORDERS IN IRAQ AND AFGHANISTAN VETERANS

(2013) Shira Maguen et al.   DEPRESSION AND ANXIETY

Sexually Dimorphic Effects of Unpredictable Early Life Adversity on Visceral Pain Behavior in a Rodent Model

(2013) Aaron Chaloner et al.   JOURNAL OF PAIN

Irritable Bowel Syndrome: Methods, Mechanisms, and Pathophysiology. Methods to assess visceral hypersensitivity in irritable bowel syndrome

(2012) D. Keszthelyi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Altered expression of glucocorticoid receptor and corticotropin-releasing factor in the central amygdala in response to elevated corticosterone

(2012) Lee Tran et al.   BEHAVIOURAL BRAIN RESEARCH

Identifying and testing candidate genetic polymorphisms in the irritable bowel syndrome (IBS): association with TNFSF15 and TNFα

(2012) Caroline Swan et al.   GUT

Sensory neuro-immune interactions differ between Irritable Bowel Syndrome subtypes

(2012) Patrick A Hughes et al.   GUT

Beyond Neurovascular: Migraine as a Dysfunctional Neurolimbic Pain Network

(2012) Morris Maizels et al.   HEADACHE

Intestinal barrier function in health and gastrointestinal disease

(2012) M. Camilleri et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Rectal hypersensitivity as hallmark for irritable bowel syndrome: defining the optimal cutoff

(2012) S. Ludidi et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Importance of stress receptor-mediated mechanisms in the amygdala on visceral pain perception in an intrinsically anxious rat

(2012) A. C. Johnson et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Sex differences in spinal processing of transient and inflammatory colorectal stimuli in the rat

(2012) Yaping Ji et al.   PAIN

A systematic literature review of 10 years of research on sex/gender and pain perception – Part 2: Do biopsychosocial factors alter pain sensitivity differently in women and men?

(2012) Mélanie Racine et al.   PAIN

MicroRNA-mediated GABAAα-1 receptor subunit down-regulation in adult spinal cord following neonatal cystitis-induced chronic visceral pain in rats

(2012) Jyoti N. Sengupta et al.   PAIN

Importance of epigenetic mechanisms in visceral pain induced by chronic water avoidance stress

(2012) L. Tran et al.   PSYCHONEUROENDOCRINOLOGY

Severity in Irritable Bowel Syndrome: A Rome Foundation Working Team Report

(2011) Douglas A Drossman et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Amygdala activation by corticosterone alters visceral and somatic pain in cycling female rats

(2011) Jenny K. Gustafsson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Differential involvement of amygdala corticosteroid receptors in visceral hyperalgesia following acute or repeated stress

(2011) Brent Myers et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Priming of adult pain responses by neonatal pain experience: maintenance by central neuroimmune activity

(2011) Simon Beggs et al.   BRAIN

Do interactions between stress and immune responses lead to symptom exacerbations in irritable bowel syndrome?

(2011) Dervla O’Malley et al.   BRAIN BEHAVIOR AND IMMUNITY

Association Between Early Adverse Life Events and Irritable Bowel Syndrome

(2011) Kara Bradford et al.   Clinical Gastroenterology and Hepatology

Epidemiology of IBS

(2011) Rok Seon Choung et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

The balancing act: endogenous modulation of pain in functional gastrointestinal disorders

(2011) C. H. Wilder-Smith   GUT

New insights into visceral hypersensitivity—clinical implications in IBS

(2011) QiQi Zhou et al.   Nature Reviews Gastroenterology & Hepatology

The Immune System in Irritable Bowel Syndrome

(2011) Giovanni Barbara et al.   Journal of Neurogastroenterology and Motility

Trauma history and risk of the irritable bowel syndrome in women veterans

(2010) D. L. White et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Meta-analysis: do irritable bowel syndrome symptoms vary between men and women?

(2010) M. A. Adeyemo et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Elevated corticosterone in the amygdala leads to persistant increases in anxiety-like behavior and pain sensitivity

(2010) Brent Myers et al.   BEHAVIOURAL BRAIN RESEARCH

Patients With Irritable Bowel Syndrome Have Altered Emotional Modulation of Neural Responses to Visceral Stimuli

(2010) Sigrid Elsenbruch et al.   GASTROENTEROLOGY

Quantitative Meta-analysis Identifies Brain Regions Activated During Rectal Distension in Irritable Bowel Syndrome

(2010) Kirsten Tillisch et al.   GASTROENTEROLOGY

Gender distribution in irritable bowel syndrome is proportional to the severity of constipation relative to diarrhea

(2010) Jeremy Herman et al.   Gender Medicine

Eight year prognosis of postinfectious irritable bowel syndrome following waterborne bacterial dysentery

(2010) J. K. Marshall et al.   GUT

Alterations in the central CRF system of two different rat models of comorbid depression and functional gastrointestinal disorders

(2010) Javier A. Bravo et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Irritable bowel syndrome: Epidemiology, diagnosis and treatment: An update for health-care practitioners

(2010) Oliver Grundmann et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Sex Steroids Localized to the Amygdala Increase Pain Responses to Visceral Stimulation in Rats

(2010) Brent Myers et al.   JOURNAL OF PAIN

Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions

(2010) Lena Öhman et al.   Nature Reviews Gastroenterology & Hepatology

Heightened central affective response to visceral sensations of pain and discomfort in IBS

(2010) g. b. c. hall et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Adrenergic Stimulation Mediates Visceral Hypersensitivity to Colorectal Distension Following Heterotypic Chronic Stress

(2009) John H. Winston et al.   GASTROENTEROLOGY

Do fluctuations in ovarian hormones affect gastrointestinal symptoms in women with irritable bowel syndrome?

(2009) Margaret M. Heitkemper et al.   Gender Medicine

Colorectal distension-induced prefrontal cortex activation in the Wistar–Kyoto rat: implications for irritable bowel syndrome

(2009) S.M. Gibney et al.   NEUROSCIENCE

Intestinal membrane permeability and hypersensitivity in the irritable bowel syndrome

(2009) QiQi Zhou et al.   PAIN

Contributions of Pain Sensitivity and Colonic Motility to IBS Symptom Severity and Predominant Bowel Habits

(2008) Motoyori Kanazawa et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Symptom Severity but Not Psychopathology Predicts Visceral Hypersensitivity in Irritable Bowel Syndrome

(2008) Patrick P.J. van der Veek et al.   Clinical Gastroenterology and Hepatology

Reciprocal changes in vanilloid (TRPV1) and endocannabinoid (CB1) receptors contribute to visceral hyperalgesia in the water avoidance stressed rat

(2008) S Hong et al.   GUT

Irritable bowel syndrome: Does gender matter?

(2008) Margaret Heitkemper et al.   JOURNAL OF PSYCHOSOMATIC RESEARCH

Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis in irritable bowel syndrome

(2008) l. chang et al.   NEUROGASTROENTEROLOGY AND MOTILITY

The visceromotor response to colorectal distention fluctuates with the estrous cycle in rats

(2008) Y. Ji et al.   NEUROSCIENCE

Estrogen alters spinal NMDA receptor activity via a PKA signaling pathway in a visceral pain model in the rat

(2008) Bin Tang et al.   PAIN

Gender differences in corticotropin and corticosterone secretion and corticotropin-releasing factor mRNA expression in the paraventricular nucleus of the hypothalamus and the central nucleus of the amygdala in response to footshock stress or psychological stress in rats

(2008) Azusa Iwasaki-Sekino et al.   PSYCHONEUROENDOCRINOLOGY