Meningiomas from a developmental perspective: exploring the crossroads between meningeal embryology and tumorigenesis

Merlin regulates signaling events at the nexus of development and cancer

(2020) Mateus Mota et al.   Cell Communication and Signaling

Landscape of immune cell gene expression is unique in predominantly WHO grade 1 skull base meningiomas when compared to convexity

(2020) Zsolt Zador et al.   Scientific Reports

Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination

(2019) Lee F Langer et al.   eLife

Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling

(2019) Krishnakali Dasgupta et al.   DEVELOPMENTAL BIOLOGY

Correlations between genomic subgroup and clinical features in a cohort of more than 3000 meningiomas

(2019) Mark W. Youngblood et al.   JOURNAL OF NEUROSURGERY

Molecular profiling predicts meningioma recurrence and reveals loss of DREAM complex repression in aggressive tumors

(2019) Akash J. Patel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gorlin-Goltz Syndrome with Intracranial Meningioma: Case Report and Review of Literature

(2019) Amit Narang et al.   World Neurosurgery

The meninges as barriers and facilitators for the movement of fluid, cells and pathogens related to the rodent and human CNS

(2018) Roy O. Weller et al.   ACTA NEUROPATHOLOGICA

Advances in meningioma genetics: novel therapeutic opportunities

(2018) Matthias Preusser et al.   Nature Reviews Neurology

Comprehensive Molecular Profiling Identifies FOXM1 as a Key Transcription Factor for Meningioma Proliferation

(2018) Harish N. Vasudevan et al.   Cell Reports

CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2011–2015

(2018) Quinn T Ostrom et al.   NEURO-ONCOLOGY

First evidence of genotype–phenotype correlations in Gorlin syndrome

(2017) D Gareth Evans et al.   JOURNAL OF MEDICAL GENETICS

DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis

(2017) Felix Sahm et al.   LANCET ONCOLOGY

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

SomaticAKT1mutations cause meningiomas colocalizing with a characteristic pattern of cranial hyperostosis

(2016) Kim M. Keppler-Noreuil et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Cerebrovascular defects in Foxc1 mutants correlate with aberrant WNT and VEGF—A pathways downstream of retinoic acid from the meninges

(2016) Swati Mishra et al.   DEVELOPMENTAL BIOLOGY

Hedgehog receptor function during craniofacial development

(2016) Guilherme M. Xavier et al.   DEVELOPMENTAL BIOLOGY

Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas

(2016) Victoria E Clark et al.   NATURE GENETICS

Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI Inhibitors

(2016) Tadas Rimkus et al.   Cancers

The Hippo pathway member YAP enhances human neural crest cell fate and migration

(2016) Christopher J. Hindley et al.   Scientific Reports

Meningiomas: knowledge base, treatment outcomes, and uncertainties. A RANO review

(2015) Leland Rogers et al.   JOURNAL OF NEUROSURGERY

Neural Crest-Derived Mesenchymal Cells Require Wnt Signaling for Their Development and Drive Invagination of the Telencephalic Midline

(2014) Youngshik Choe et al.   PLoS One

Targeting PI3K/Akt/mTOR Signaling in Cancer

(2014) Camillo Porta et al.   Frontiers in Oncology

Loss-of-function mutations in SMARCE1 cause an inherited disorder of multiple spinal meningiomas

(2013) Miriam J Smith et al.   NATURE GENETICS

Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations

(2013) Priscilla K Brastianos et al.   NATURE GENETICS

Genomic Analysis of Non-NF2 Meningiomas Reveals Mutations in TRAF7, KLF4, AKT1, and SMO

(2013) V. E. Clark et al.   SCIENCE

Loss of SUFU Function in Familial Multiple Meningioma

(2012) Mervi Aavikko et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The cranial dura mater: a review of its history, embryology, and anatomy

(2012) Nimer Adeeb et al.   CHILDS NERVOUS SYSTEM

A Cascade of Morphogenic Signaling Initiated by the Meninges Controls Corpus Callosum Formation

(2012) Youngshik Choe et al.   NEURON

We have got you ‘covered’: how the meninges control brain development

(2011) Julie A Siegenthaler et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Cranial meningiomas in 411 neurofibromatosis type 2 (NF2) patients with proven gene mutations: clear positional effect of mutations, but absence of female severity effect on age at onset

(2011) M. J. Smith et al.   JOURNAL OF MEDICAL GENETICS

Germline SMARCB1 mutation predisposes to multiple meningiomas and schwannomas with preferential location of cranial meningiomas at the falx cerebri

(2011) Pepijn van den Munckhof et al.   NEUROGENETICS

A Mosaic Activating Mutation inAKT1Associated with the Proteus Syndrome

(2011) Marjorie J. Lindhurst et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes

(2011) M Kalamarides et al.   ONCOGENE

Genomic Profiling Reveals Alternative Genetic Pathways of Meningioma Malignant Progression Dependent on the Underlying NF2 Status

(2010) S. Goutagny et al.   CLINICAL CANCER RESEARCH

The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals

(2010) Nailing Zhang et al.   DEVELOPMENTAL CELL

Meningioma mouse models

(2010) Michel Kalamarides et al.   JOURNAL OF NEURO-ONCOLOGY

Pathological classification and molecular genetics of meningiomas

(2010) Christian Mawrin et al.   JOURNAL OF NEURO-ONCOLOGY

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(2010) Ingrid Laurendeau et al.   MOLECULAR MEDICINE

CORRESPONDENCE OF TUMOR LOCALIZATION WITH TUMOR RECURRENCE AND CYTOGENETIC PROGRESSION IN MENINGIOMAS

(2009) Ralf Ketter et al.   NEUROSURGERY

Development and tissue origins of the mammalian cranial base

(2008) B. McBratney-Owen et al.   DEVELOPMENTAL BIOLOGY

Impaired meningeal development in association with apical expansion of calvarial bone osteogenesis in the Foxc1 mutant

(2008) Philaiporn Vivatbutsiri et al.   JOURNAL OF ANATOMY

Zic Deficiency in the Cortical Marginal Zone and Meninges Results in Cortical Lamination Defects Resembling Those in Type II Lissencephaly

(2008) T. Inoue et al.   JOURNAL OF NEUROSCIENCE

Cell lineage in mammalian craniofacial mesenchyme

(2008) Toshiyuki Yoshida et al.   MECHANISMS OF DEVELOPMENT

Natural History of Meningioma Development in Mice Reveals: A Synergy of Nf2 and p16Ink4aMutations

(2007) Michel Kalamarides et al.   BRAIN PATHOLOGY