Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination

Atypical Teratoid/Rhabdoid Tumor of the Spinal Cord in a Child: Case Report and Comprehensive Review of the Literature

(2018) Mohammed Babgi et al.   PEDIATRIC NEUROSURGERY

Postnatal overnutrition alters the orexigenic effects of melanin-concentrating hormone (MCH) and reduces MCHR1 hypothalamic expression on spontaneous feeding and fasting

(2018) Marcel Pérez-Morales et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation

(2018) Brittany C. Michel et al.   NATURE CELL BIOLOGY

A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells

(2018) Jovylyn Gatchalian et al.   Nature Communications

SMARCB1 is required for widespread BAF complex–mediated activation of enhancers and bivalent promoters

(2017) Robert T Nakayama et al.   NATURE GENETICS

Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers

(2017) H. Courtney Hodges et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Myc target gene, long intergenic noncoding RNA, Linc00176 in hepatocellular carcinoma regulates cell cycle and cell survival by titrating tumor suppressor microRNAs

(2017) D D H Tran et al.   ONCOGENE

SMARCB1-deficient Tumors of Childhood: A Practical Guide

(2017) Bruce R Pawel   PEDIATRIC AND DEVELOPMENTAL PATHOLOGY

The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers

(2017) Burak H. Alver et al.   Nature Communications

Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers

(2017) H. Courtney Hodges et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The pioneer factor OCT4 requires the chromatin remodeller BRG1 to support gene regulatory element function in mouse embryonic stem cells

(2017) Hamish W King et al.   eLife

Comprehensive profiling reveals mechanisms of SOX2-mediated cell fate specification in human ESCs and NPCs

(2016) Chenlin Zhou et al.   CELL RESEARCH

Neuronal Dysfunction in iPSC-Derived Medium Spiny Neurons from Chorea-Acanthocytosis Patients Is Reversed by Src Kinase Inhibition and F-Actin Stabilization

(2016) Nancy Stanslowsky et al.   JOURNAL OF NEUROSCIENCE

Dynamics of BAF–Polycomb complex opposition on heterochromatin in normal and oncogenic states

(2016) Cigall Kadoch et al.   NATURE GENETICS

SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation

(2016) Xiaofeng Wang et al.   NATURE GENETICS

The occurrence of intracranial rhabdoid tumours in mice depends on temporal control of Smarcb1 inactivation

(2016) Zhi-Yan Han et al.   Nature Communications

Brg1 modulates enhancer activation in mesoderm lineage commitment

(2015) J. M. Alexander et al.   DEVELOPMENT

Chromatin architecture reorganization during stem cell differentiation

(2015) Jesse R. Dixon et al.   NATURE

Orchestrating high-throughput genomic analysis with Bioconductor

(2015) Wolfgang Huber et al.   NATURE METHODS

dbSUPER: a database of super-enhancers in mouse and human genome

(2015) Aziz Khan et al.   NUCLEIC ACIDS RESEARCH

MiRNA-Mediated Regulation of the SWI/SNF Chromatin Remodeling Complex Controls Pluripotency and Endodermal Differentiation in Human ESCs

(2015) Staton L. Wade et al.   STEM CELLS

Transcriptional Repression by the BRG1-SWI/SNF Complex Affects the Pluripotency of Human Embryonic Stem Cells

(2014) Xiaoli Zhang et al.   Stem Cell Reports

Super-Enhancers in the Control of Cell Identity and Disease

(2013) Denes Hnisz et al.   CELL

The DLK signalling pathway—a double-edged sword in neural development and regeneration

(2013) Andrea Tedeschi et al.   EMBO REPORTS

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

Software for Computing and Annotating Genomic Ranges

(2013) Michael Lawrence et al.   PLoS Computational Biology

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Human PIH1 associates with histone H4 to mediate the glucose-dependent enhancement of pre-rRNA synthesis

(2012) Niu Zhai et al.   Journal of Molecular Cell Biology

False positive peaks in ChIP-seq and other sequencing-based functional assays caused by unannotated high copy number regions

(2011) Joseph K. Pickrell et al.   BIOINFORMATICS

Intrinsic transition of embryonic stem-cell differentiation into neural progenitors

(2011) Daisuke Kamiya et al.   NATURE

The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo

(2011) Kristen L. Meerbrey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lnx-2b restricts gsc expression to the dorsal mesoderm by limiting Nodal and Bozozok activity

(2010) Hyunju Ro et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Epigenetic Antagonism between Polycomb and SWI/SNF Complexes during Oncogenic Transformation

(2010) Boris G. Wilson et al.   CANCER CELL

Analysis of the Hand1 cell lineage reveals novel contributions to cardiovascular, neural crest, extra-embryonic, and lateral mesoderm derivatives

(2010) Ralston M. Barnes et al.   DEVELOPMENTAL DYNAMICS

Ubiquitin-dependent and Ubiquitin-independent Control of Subunit Stoichiometry in the SWI/SNF Complex

(2010) Brian R. Keppler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prenatal Presentation of a Metastasizing Rhabdoid Tumor With Homozygous Deletion of the SMARCB1 Gene

(2010) Shahrzad Negahban et al.   JOURNAL OF CLINICAL ONCOLOGY

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

A unique chromatin signature uncovers early developmental enhancers in humans

(2010) Alvaro Rada-Iglesias et al.   NATURE

Srg3, a mouse homolog of BAF155, is a novel p53 target and acts as a tumor suppressor by modulating p21WAF1/CIP1 expression

(2010) J Ahn et al.   ONCOGENE

rtracklayer: an R package for interfacing with genome browsers

(2009) M. Lawrence et al.   BIOINFORMATICS

An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency

(2009) L. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Smarcc1/Baf155 Couples Self-Renewal Gene Repression with Changes in Chromatin Structure in Mouse Embryonic Stem Cells

(2009) Christoph Schaniel et al.   STEM CELLS

Cohesins Functionally Associate with CTCF on Mammalian Chromosome Arms

(2008) Vania Parelho et al.   CELL