Risk to human health related to the presence of perfluoroalkyl substances in food
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Title
Risk to human health related to the presence of perfluoroalkyl substances in food
Authors
Keywords
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Journal
EFSA Journal
Volume 18, Issue 9, Pages -
Publisher
Wiley
Online
2020-09-17
DOI
10.2903/j.efsa.2020.6223
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- Toxicological evaluation of ammonium perfluorobutyrate in rats: Twenty-eight-day and ninety-day oral gavage studies
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- Promotion of Hepatocarcinogenesis by Perfluoroalkyl Acids in Rainbow Trout
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- Impact of perfluorooctanesulfonate and perfluorooctanoic acid on human peripheral leukocytes
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- Ammonium perfluorooctanoate may cause testosterone reduction by adversely affecting testis in relation to PPARα
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- Perfluoroalkyl and polyfluoroalkyl substances in the environment: Terminology, classification, and origins
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- Development of a Fluorescence Model for the Binding of Medium- to Long-Chain Perfluoroalkyl Acids to Human Serum Albumin Through a Mechanistic Evaluation of Spectroscopic Evidence
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- Levels in food and beverages and daily intake of perfluorinated compounds in Norway
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- Perfluorooctanesulfonate and perfluorooctanoic acid exposures of the Italian general population
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- Diet and particularly seafood are major sources of perfluorinated compounds in humans
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- Use of simple pharmacokinetic modeling to characterize exposure of Australians to perfluorooctanoic acid and perfluorooctane sulfonic acid
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- Exposure to polyfluoroalkyl chemicals during pregnancy is not associated with offspring age at menarche in a contemporary British cohort
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- Exploring Indirect Sources of Human Exposure to Perfluoroalkyl Carboxylates (PFCAs): Evaluating Uptake, Elimination, and Biotransformation of Polyfluoroalkyl Phosphate Esters (PAPs) in the Rat
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- Accumulation and Clearance of Perfluorooctanoic Acid (PFOA) in Current and Former Residents of an Exposed Community
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- Distribution and sources of polyfluoroalkyl substances (PFAS) in the River Rhine watershed
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- Noncovalent Interactions of Long-Chain Perfluoroalkyl Acids with Serum Albumin
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- Temporal Trends of Perfluorinated Surfactants in Swedish Peregrine Falcon Eggs (Falco peregrinus), 1974−2007
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- Changes in Concentrations of Perfluorinated Compounds, Polybrominated Diphenyl Ethers, and Polychlorinated Biphenyls in Norwegian Breast-Milk during Twelve Months of Lactation
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- Pre- and Postnatal Exposure to Perfluorinated Compounds (PFCs)
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- Indoor Contamination with Hexabromocyclododecanes, Polybrominated Diphenyl Ethers, and Perfluoroalkyl Compounds: An Important Exposure Pathway for People?
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- Determinants of Plasma PFOA and PFOS Levels Among 652 Danish Men
- (2010) Kirsten T. Eriksen et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Role of Peroxisome Proliferator-activated Receptor-α in Hepatobiliary Injury Induced by Ammonium Perfluorooctanoate in Mouse Liver
- (2010) Mutsuko MINATA et al. INDUSTRIAL HEALTH
- PFOS or PreFOS? Are perfluorooctane sulfonate precursors (PreFOS) important determinants of human and environmental perfluorooctane sulfonate (PFOS) exposure?
- (2010) Jonathan W. Martin et al. JOURNAL OF ENVIRONMENTAL MONITORING
- An assessment of the exposure of Americans to perfluorooctane sulfonate: A comparison of estimated intake with values inferred from NHANES data
- (2010) Peter P Egeghy et al. Journal of Exposure Science and Environmental Epidemiology
- Effects of perfluorooctanoic acid (PFOA) exposure to pregnant mice on reproduction
- (2010) Doha Yahia et al. JOURNAL OF TOXICOLOGICAL SCIENCES
- Genotoxic potential of the perfluorinated chemicals PFOA, PFOS, PFBS, PFNA and PFHxA in human HepG2 cells
- (2010) Kirsten Thorup Eriksen et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- Evaluation and prediction of pharmacokinetics of PFOA and PFOS in the monkey and human using a PBPK model
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- Perfluorooctanoic Acid Effects on Steroid Hormone and Growth Factor Levels Mediate Stimulation of Peripubertal Mammary Gland Development in C57Bl/6 Mice
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- Characterization of Cellular Uptake of Perfluorooctanoate via Organic Anion-Transporting Polypeptide 1A2, Organic Anion Transporter 4, and Urate Transporter 1 for Their Potential Roles in Mediating Human Renal Reabsorption of Perfluorocarboxylates
- (2010) Ching-Hui Yang et al. TOXICOLOGICAL SCIENCES
- In vitro evaluation of the immunotoxic potential of perfluorinated compounds (PFCs)
- (2010) Emanuela Corsini et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Investigation of the Associations Between Low-Dose Serum Perfluorinated Chemicals and Liver Enzymes in US Adults
- (2009) Chien-Yu Lin et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Carryover of Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonate (PFOS) from Soil to Plants
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- Subacute exposure to N-ethyl perfluorooctanesulfonamidoethanol results in the formation of perfluorooctanesulfonate and alters superoxide dismutase activity in female rats
- (2009) Wei Xie et al. ARCHIVES OF TOXICOLOGY
- Chronic effects of perfluorooctanesulfonate exposure on immunotoxicity in adult male C57BL/6 mice
- (2009) Guang-Hui Dong et al. ARCHIVES OF TOXICOLOGY
- Kinetics of 8-2 fluorotelomer alcohol and its metabolites, and liver glutathione status following daily oral dosing for 45 days in male and female rats
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- Temporal trends of polyfluoroalkyl compounds in harbor seals (Phoca vitulina) from the German Bight, 1999–2008
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- 8-2 Fluorotelomer alcohol aerobic soil biodegradation: Pathways, metabolites, and metabolite yields
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- Do Perfluoroalkyl Compounds Impair Human Semen Quality?
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- The C8 Health Project: Design, Methods, and Participants
- (2009) Stephanie J. Frisbee et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Rate of Decline in Serum PFOA Concentrations after Granular Activated Carbon Filtration at Two Public Water Systems in Ohio and West Virginia
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- Exposure to Polyfluoroalkyl Chemicals and Cholesterol, Body Weight, and Insulin Resistance in the General U.S. Population
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- Branched Perfluorooctane Sulfonate Isomer Quantification and Characterization in Blood Serum Samples by HPLC/ESI-MS(/MS)
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- Polyfluorinated Compounds in the Atmosphere of the Atlantic and Southern Oceans: Evidence for a Global Distribution
- (2009) Annekatrin Dreyer et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Time Trends and the Influence of Age and Gender on Serum Concentrations of Perfluorinated Compounds in Archived Human Samples
- (2009) Line S. Haug et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Occurrence of Perfluoroalkyl Carboxylates and Sulfonates in Drinking Water Utilities and Related Waters from the United States
- (2009) Oscar Quiñones et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Perfluoroalkyl Contaminants in an Arctic Marine Food Web: Trophic Magnification and Wildlife Exposure
- (2009) Barry C. Kelly et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Exposure to perfluorinated compounds in Catalonia, Spain, through consumption of various raw and cooked foodstuffs, including packaged food
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- Perfluorinated compounds in delivering women from south central Vietnam
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- Congener-specific organic carbon-normalized soil and sediment-water partitioning coefficients for the C1through C8perfluoroalkyl carboxylic and sulfonic acids
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- Maternal exposure to perfluorinated acids and fetal growth
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- Systems Biological Responses to Chronic Perfluorododecanoic Acid Exposure by Integrated Metabonomic and Transcriptomic Studies
- (2009) Lina Ding et al. JOURNAL OF PROTEOME RESEARCH
- Effect of perfluorooctane sulfonate (PFOS) on influenza A virus-induced mortality in female B6C3F1 mice
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- Phenotypic dichotomy following developmental exposure to perfluorooctanoic acid (PFOA) in female CD-1 mice: Low doses induce elevated serum leptin and insulin, and overweight in mid-life☆
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- Exploratory assessment of perfluorinated compounds and human thyroid function
- (2009) Michael S. Bloom et al. PHYSIOLOGY & BEHAVIOR
- The effect of perfluorododecanonic acid on endocrine status, sex hormones and expression of steroidogenic genes in pubertal female rats
- (2009) Zhimin Shi et al. REPRODUCTIVE TOXICOLOGY
- Evaluation of potential reproductive and developmental toxicity of potassium perfluorohexanesulfonate in Sprague Dawley rats
- (2009) John L. Butenhoff et al. REPRODUCTIVE TOXICOLOGY
- Perfluoroalkyl chemicals and human fetal development: An epidemiologic review with clinical and toxicological perspectives
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- A 90-day repeated dose oral (gavage) toxicity study of perfluorohexanoic acid (PFHxA) in rats (with functional observational battery and motor activity determinations)
- (2009) Christopher P. Chengelis et al. REPRODUCTIVE TOXICOLOGY
- Suppression of Humoral Immunity by Perfluorooctanoic Acid is Independent of Elevated Serum Corticosterone Concentration in Mice
- (2009) Jamie C. DeWitt et al. TOXICOLOGICAL SCIENCES
- Structure-Activity Relationships and Human Relevance for Perfluoroalkyl Acid–Induced Transcriptional Activation of Peroxisome Proliferation in Liver Cell Cultures
- (2009) James A. Bjork et al. TOXICOLOGICAL SCIENCES
- Roles of Rat Renal Organic Anion Transporters in Transporting Perfluorinated Carboxylates with Different Chain Lengths
- (2009) Yi M. Weaver et al. TOXICOLOGICAL SCIENCES
- Alterations of Cytokines and MAPK Signaling Pathways are Related to the Immunotoxic Effect of Perfluorononanoic Acid
- (2009) Xuemei Fang et al. TOXICOLOGICAL SCIENCES
- Competitive Binding of Poly- and Perfluorinated Compounds to the Thyroid Hormone Transport Protein Transthyretin
- (2009) Jana M. Weiss et al. TOXICOLOGICAL SCIENCES
- Differential Hepatic Effects of Perfluorobutyrate Mediated by Mouse and Human PPAR-α
- (2009) Jennifer E. Foreman et al. TOXICOLOGICAL SCIENCES
- A two-generation oral gavage reproduction study with potassium perfluorobutanesulfonate (K+PFBS) in Sprague Dawley rats
- (2009) Paul H. Lieder et al. TOXICOLOGY
- The atrophy and changes in the cellular compositions of the thymus and spleen observed in mice subjected to short-term exposure to perfluorooctanesulfonate are high-dose phenomena mediated in part by peroxisome proliferator-activated receptor-alpha (PPARα)
- (2009) Mousumi Rahman Qazi et al. TOXICOLOGY
- High-dose, short-term exposure of mice to perfluorooctanesulfonate (PFOS) or perfluorooctanoate (PFOA) affects the number of circulating neutrophils differently, but enhances the inflammatory responses of macrophages to lipopolysaccharide (LPS) in a similar fashion
- (2009) Mousumi R. Qazi et al. TOXICOLOGY
- Toxicological evaluation of sodium perfluorohexanoate
- (2009) Scott E. Loveless et al. TOXICOLOGY
- Microgram-order ammonium perfluorooctanoate may activate mouse peroxisome proliferator-activated receptor α, but not human PPARα
- (2009) Toshiki Nakamura et al. TOXICOLOGY
- 28-Day dietary exposure of mice to a low total dose (7mg/kg) of perfluorooctanesulfonate (PFOS) alters neither the cellular compositions of the thymus and spleen nor humoral immune responses: Does the route of administration play a pivotal role in PFOS-induced immunotoxicity?
- (2009) Mousumi Rahman Qazi et al. TOXICOLOGY
- Chronic exposure to perfluorododecanoic acid disrupts testicular steroidogenesis and the expression of related genes in male rats
- (2009) Zhimin Shi et al. TOXICOLOGY LETTERS
- Environment and endocrinology: The case of thyroidology
- (2008) J. Köhrle ANNALES D ENDOCRINOLOGIE
- Immunotoxic changes associated with a 7-day oral exposure to perfluorooctanesulfonate (PFOS) in adult male C57BL/6 mice
- (2008) Li Zheng et al. ARCHIVES OF TOXICOLOGY
- Spatial trends of polyfluorinated compounds in guillemot (Uria aalge) eggs from North-Western Europe
- (2008) Karin Löfstrand et al. CHEMOSPHERE
- Association Among Serum Perfluoroalkyl Chemicals, Glucose Homeostasis, and Metabolic Syndrome in Adolescents and Adults
- (2008) C.-Y. Lin et al. DIABETES CARE
- 90-Day Oral Gavage Toxicity Study of 8-2 Fluorotelomer Alcohol in Rats
- (2008) Gregory S. Ladics et al. DRUG AND CHEMICAL TOXICOLOGY
- Perfluorooctanoic Acid–Induced Immunomodulation in Adult C57BL/6J or C57BL/6N Female Mice
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- Biomonitoring of Perfluorinated Compounds in Children and Adults Exposed to Perfluorooctanoate-Contaminated Drinking Water
- (2008) Jürgen Hölzer et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Biomonitoring of Perfluorochemicals in Plasma of New York State Personnel Responding to the World Trade Center Disaster
- (2008) Lin Tao et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Dietary Predictors of Perfluorinated Chemicals: A Study from the Danish National Birth Cohort
- (2008) Thorhallur I. Halldorsson et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Perfluorooctanoic acid alters T lymphocyte phenotypes and cytokine expression in mice
- (2008) Hee-Young Son et al. ENVIRONMENTAL TOXICOLOGY
- DISPOSITION OF PERFLUORINATED ACID ISOMERS IN SPRAGUE-DAWLEY RATS; PART 1: SINGLE DOSE
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- DISPOSITION OF PERFLUORINATED ACID ISOMERS IN SPRAGUE-DAWLEY RATS; PART 2: SUBCHRONIC DOSE
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- EFFECTS OF PERFLUOROOCTANE SULFONATE ON RAT THYROID HORMONE BIOSYNTHESIS AND METABOLISM
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- Preliminary observations on perfluorinated compounds in plasma samples (1977–2004) of young German adults from an area with perfluorooctanoate-contaminated drinking water
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- Perfluorinated compounds – Exposure assessment for the general population in western countries
- (2008) Hermann Fromme et al. INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
- Trace analysis of per- and polyfluorinated alkyl substances in various matrices—How do current methods perform?
- (2008) Annika Jahnke et al. JOURNAL OF CHROMATOGRAPHY A
- Neonatal death of mice treated with perfluorooctane sulfonate
- (2008) Doha Yahia et al. JOURNAL OF TOXICOLOGICAL SCIENCES
- Immunomodulatory Effects of Dietary Potassium Perfluorooctane Sulfonate (PFOS) Exposure in Adult Sprague-Dawley Rats
- (2008) David E. Lefebvre et al. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES
- Differential effects of peripubertal exposure to perfluorooctanoic acid on mammary gland development in C57Bl/6 and Balb/c mouse strains
- (2008) Chengfeng Yang et al. REPRODUCTIVE TOXICOLOGY
- Effects of perfluorooctanoic acid on mouse mammary gland development and differentiation resulting from cross-foster and restricted gestational exposures
- (2008) Sally S. White et al. REPRODUCTIVE TOXICOLOGY
- Developmental toxicity of perfluorooctane sulfonate (PFOS) is not dependent on expression of peroxisome proliferator activated receptor-alpha (PPARα) in the mouse
- (2008) Barbara D. Abbott et al. REPRODUCTIVE TOXICOLOGY
- Estimating Consumer Exposure to PFOS and PFOA
- (2008) David Trudel et al. RISK ANALYSIS
- Comparative Hepatic Effects of Perfluorooctanoic Acid and WY 14,643 in PPAR-α Knockout and Wild-type Mice
- (2008) Douglas C. Wolf et al. TOXICOLOGIC PATHOLOGY
- Critical Role of PPAR-α in Perfluorooctanoic Acid– and Perfluorodecanoic Acid–Induced Downregulation of Oatp Uptake Transporters in Mouse Livers
- (2008) Xingguo Cheng et al. TOXICOLOGICAL SCIENCES
- Evaluation of the Immune System in Rats and Mice Administered Linear Ammonium Perfluorooctanoate
- (2008) Scott E. Loveless et al. TOXICOLOGICAL SCIENCES
- Nrf2- and PPARα-Mediated Regulation of Hepatic Mrp Transporters after Exposure to Perfluorooctanoic Acid and Perfluorodecanoic Acid
- (2008) Jonathan M. Maher et al. TOXICOLOGICAL SCIENCES
- Effects of Perfluorobutyrate Exposure during Pregnancy in the Mouse
- (2008) Kaberi P. Das et al. TOXICOLOGICAL SCIENCES
- Gestational Exposure to Perfluorooctane Sulfonate Suppresses Immune Function in B6C3F1 Mice
- (2008) Deborah E. Keil et al. TOXICOLOGICAL SCIENCES
- Perfluorocarboxylic Acids Induce Cytochrome P450 Enzymes in Mouse Liver through Activation of PPAR-α and CAR Transcription Factors
- (2008) Xingguo Cheng et al. TOXICOLOGICAL SCIENCES
- Toxicogenomic Dissection of the Perfluorooctanoic Acid Transcript Profile in Mouse Liver: Evidence for the Involvement of Nuclear Receptors PPARα and CAR
- (2008) Mitchell B. Rosen et al. TOXICOLOGICAL SCIENCES
- Immunotoxic Effects of Perfluorononanoic Acid on BALB/c Mice
- (2008) Xuemei Fang et al. TOXICOLOGICAL SCIENCES
- Suppression of Humoral Immunity in Mice following Exposure to Perfluorooctane Sulfonate
- (2008) Margie M. Peden-Adams et al. TOXICOLOGICAL SCIENCES
- Cleft palate caused by perfluorooctane sulfonate is caused mainly by extrinsic factors
- (2008) Saho Era et al. TOXICOLOGY
- Toxicological evaluation of potassium perfluorobutanesulfonate in a 90-day oral gavage study with Sprague–Dawley rats
- (2008) Paul H. Lieder et al. TOXICOLOGY
- Neonatal exposure to perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) causes neurobehavioural defects in adult mice
- (2007) N. Johansson et al. NEUROTOXICOLOGY
- Thyroid hormone status and pituitary function in adult rats given oral doses of perfluorooctanesulfonate (PFOS)
- (2007) Shu-Ching Chang et al. TOXICOLOGY
- Lipid homeostasis and oxidative stress in the liver of male rats exposed to perfluorododecanoic acid
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