Bayesian evaluation of a physiologically based pharmacokinetic (PBPK) model for perfluorooctane sulfonate (PFOS) to characterize the interspecies uncertainty between mice, rats, monkeys, and humans: Development and performance verification

Published 2019 View Full Article

Title

Bayesian evaluation of a physiologically based pharmacokinetic (PBPK) model for perfluorooctane sulfonate (PFOS) to characterize the interspecies uncertainty between mice, rats, monkeys, and humans: Development and performance verification

Authors

Keywords

Interspecies extrapolation, Markov chain Monte Carlo (MCMC), Perfluoroalkyl substances (PFAS), Perfluorooctane sulfonate (PFOS), Physiologically based pharmacokinetic (PBPK) modeling, Risk assessment

Journal

ENVIRONMENT INTERNATIONAL

Volume 129, Issue -, Pages 408-422

Publisher

Elsevier BV

Online

2019-05-29

DOI

10.1016/j.envint.2019.03.058

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