Long non-coding RNAs in liver diseases: Focusing on nonalcoholic fatty liver disease, alcohol-related liver disease, and cholestatic liver disease

The Roles and Mechanisms of lncRNAs in Liver Fibrosis

(2020) Zhi He et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cholangiocyte-Derived Exosomal lncRNA H19 Promotes Macrophage Activation and Hepatic Inflammation under Cholestatic Conditions

(2020) Xiaojiaoyang Li et al.   Cells

The mechanism of lncRNA H19 in fibrosis and its potential as novel therapeutic target

(2020) Xiaoying Jiang et al.   MECHANISMS OF AGEING AND DEVELOPMENT

H19 potentiates let-7 family expression through reducing PTBP1 binding to their precursors in cholestasis

(2019) Li Zhang et al.   Cell Death & Disease

LncRNA-H19 promotes hepatic lipogenesis by directly regulating miR-130a/PPARγ axis in nonalcoholic fatty liver disease

(2019) Jun Liu et al.   BIOSCIENCE REPORTS

Long non‐coding RNA H19 contributes to cholangiocyte proliferation and cholestatic liver fibrosis in biliary atresia

(2019) Yongtao Xiao et al.   HEPATOLOGY

Long non‐coding RNA (lncRNA) H19 induces hepatic steatosis through activating MLXIPL and mTORC1 networks in hepatocytes

(2019) Hao Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Long noncoding RNA lncARSR promotes hepatic lipogenesis via Akt/SREBP-1c pathway and contributes to the pathogenesis of nonalcoholic steatohepatitis

(2018) Ming Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

LncRNA Gm5091 alleviates alcoholic hepatic fibrosis by sponging miR-27b/23b/24 in mice

(2018) Bo Zhou et al.   CELL BIOLOGY INTERNATIONAL

Long Noncoding RNA lncSHGL Recruits hnRNPA1 to Suppress Hepatic Gluconeogenesis and Lipogenesis

(2018) Junpei Wang et al.   DIABETES

Long noncoding RNA H19 interacts with polypyrimidine tract-binding protein 1 to reprogram hepatic lipid homeostasis

(2018) Chune Liu et al.   HEPATOLOGY

Long noncoding RNA lncARSR promotes hepatic cholesterol biosynthesis via modulating Akt/SREBP-2/HMGCR pathway

(2018) Jiabin Huang et al.   LIFE SCIENCES

Novel and emerging therapies for cholestatic liver diseases

(2018) Jordan Goldstein et al.   LIVER INTERNATIONAL

The Long Non-coding RNA MEG3/miR-let-7c-5p Axis Regulates Ethanol-Induced Hepatic Steatosis and Apoptosis by Targeting NLRC5

(2018) Qin Wang et al.   Frontiers in Pharmacology

lncRNA MEG3 promotes hepatic insulin resistance by serving as a competing endogenous RNA of miR-214 to regulate ATF4 expression

(2018) Xiang Zhu et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

A liver-specific long noncoding RNA with a role in cell viability is elevated in human nonalcoholic steatohepatitis

(2017) Biljana Atanasovska et al.   HEPATOLOGY

The role of long noncoding RNA H19 in gender disparity of cholestatic liver injury in multidrug resistance 2 gene knockout mice

(2017) Xiaojiaoyang Li et al.   HEPATOLOGY

H19 promotes cholestatic liver fibrosis by preventing ZEB1-mediated inhibition of epithelial cell adhesion molecule

(2017) Yongfeng Song et al.   HEPATOLOGY

Down-regulation of lncRNA-NEAT1 alleviated the non-alcoholic fatty liver disease via mTOR/S6K1 signaling pathway

(2017) Xiang Wang   JOURNAL OF CELLULAR BIOCHEMISTRY

Mechanisms of hepatic stellate cell activation

(2017) Takuma Tsuchida et al.   Nature Reviews Gastroenterology & Hepatology

Altered expression of MALAT1 lncRNA in nonalcoholic steatohepatitis fibrosis regulates CXCL5 in hepatic stellate cells

(2017) Fatjon Leti et al.   Translational Research

How do lncRNAs regulate transcription?

(2017) Yicheng Long et al.   Science Advances

Transcriptional and Post-transcriptional Gene Regulation by Long Non-coding RNA

(2017) Iain M. Dykes et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Upregulation of lncRNA MEG3 promotes hepatic insulin resistance via increasing FoxO1 expression

(2016) Xiang Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Alcoholic Liver Disease in Asia, Europe, and North America

(2016) Suthat Liangpunsakul et al.   GASTROENTEROLOGY

Long noncoding RNA MEG3 induces cholestatic liver injury by interaction with PTBP1 to facilitate shp mRNA decay

(2016) Li Zhang et al.   HEPATOLOGY

Unique features of long non-coding RNA biogenesis and function

(2016) Jeffrey J. Quinn et al.   NATURE REVIEWS GENETICS

Long noncoding RNA MALAT1 promotes hepatic steatosis and insulin resistance by increasing nuclear SREBP-1c protein stability

(2016) Caifeng Yan et al.   Scientific Reports

LncRNA SRA promotes hepatic steatosis through repressing the expression of adipose triglyceride lipase (ATGL)

(2016) Gang Chen et al.   Scientific Reports

MALAT1 functions as a competing endogenous RNA to mediate Rac1 expression by sequestering miR-101b in liver fibrosis

(2015) Fujun Yu et al.   CELL CYCLE

Conjugated bile acid-activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression

(2015) Masayuki Nagahashi et al.   HEPATOLOGY

Long non-coding RNA MALAT1 regulates hyperglycaemia induced inflammatory process in the endothelial cells

(2015) Prasanth Puthanveetil et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Nonalcoholic fatty liver disease, metabolic risk factors, and hepatocellular carcinoma: An open question

(2015) Letiția Adela Maria Streba   WORLD JOURNAL OF GASTROENTEROLOGY

Conjugated bile acids promote cholangiocarcinoma cell invasive growth through activation of sphingosine 1-phosphate receptor 2

(2014) Runping Liu et al.   HEPATOLOGY

Regulatory non-coding RNAs: revolutionizing the RNA world

(2014) Biao Huang et al.   MOLECULAR BIOLOGY REPORTS

Functional interactions among microRNAs and long noncoding RNAs

(2014) Je-Hyun Yoon et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Evolutionary conservation of long non-coding RNAs; sequence, structure, function

(2013) Per Johnsson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Tackling Structures of Long Noncoding RNAs

(2013) Irina Novikova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Global burden of alcoholic liver diseases

(2013) Jürgen Rehm et al.   JOURNAL OF HEPATOLOGY

Signaling Pathways Differentially Affect RNA Polymerase II Initiation, Pausing, and Elongation Rate in Cells

(2013) Charles G. Danko et al.   MOLECULAR CELL

Retinoic acids and hepatic stellate cells in liver disease

(2012) Young-Sun Lee et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Landscape of transcription in human cells

(2012) Sarah Djebali et al.   NATURE

The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r

(2012) Andrew Keniry et al.   NATURE CELL BIOLOGY

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

(2011) Leonardo Salmena et al.   CELL

Molecular Mechanisms of Long Noncoding RNAs

(2011) Kevin C. Wang et al.   MOLECULAR CELL

lincRNAs act in the circuitry controlling pluripotency and differentiation

(2011) Mitchell Guttman et al.   NATURE

Role of nuclear receptor SHP in metabolism and cancer

(2010) Yuxia Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

MicroRNA sponges: Progress and possibilities

(2010) M. S. Ebert et al.   RNA

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY