Long noncoding RNA MEG3 induces cholestatic liver injury by interaction with PTBP1 to facilitate shp mRNA decay

Nuclear Receptors as Therapeutic Targets in Liver Disease: Are We There Yet?

(2016) Swetha Rudraiah et al.   Annual Review of Pharmacology and Toxicology

Upregulation of lncRNA MEG3 promotes hepatic insulin resistance via increasing FoxO1 expression

(2016) Xiang Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A novel long noncoding RNA Lnc-HC binds hnRNPA2B1 to regulate expressions of Cyp7a1 and Abca1 in hepatocytic cholesterol metabolism

(2016) Xi Lan et al.   HEPATOLOGY

Bcl2 is a critical regulator of bile acid homeostasis by dictating Shp and lncRNA H19 function

(2016) Yuxia Zhang et al.   Scientific Reports

The Long Noncoding RNA Pnky Regulates Neuronal Differentiation of Embryonic and Postnatal Neural Stem Cells

(2015) Alexander D. Ramos et al.   Cell Stem Cell

Interactions Between Nuclear Receptor SHP and FOXA1 Maintain Oscillatory Homocysteine Homeostasis in Mice

(2015) Hiroyuki Tsuchiya et al.   GASTROENTEROLOGY

Long noncoding RNADANCRincreases stemness features of hepatocellular carcinoma by derepression ofCTNNB1

(2015) Sheng-xian Yuan et al.   HEPATOLOGY

Small heterodimer partner/neuronal PAS domain protein 2 axis regulates the oscillation of liver lipid metabolism

(2015) Sang Min Lee et al.   HEPATOLOGY

Epigenetic Regulation of the lncRNA MEG3 and Its Target c-MET in Pancreatic Neuroendocrine Tumors

(2015) Sita D. Modali et al.   MOLECULAR ENDOCRINOLOGY

MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA–DNA triplex structures

(2015) Tanmoy Mondal et al.   Nature Communications

Inhibitory effects of long noncoding RNA MEG3 on hepatic stellate cells activation and liver fibrogenesis

(2014) Yong He et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Long noncoding RNA in liver diseases

(2014) Kenji Takahashi et al.   HEPATOLOGY

E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network

(2014) Yuxia Zhang et al.   HEPATOLOGY

The Long Noncoding RNAs NEAT1 and MALAT1 Bind Active Chromatin Sites

(2014) Jason A. West et al.   MOLECULAR CELL

An Evolutionarily Conserved Long Noncoding RNA TUNA Controls Pluripotency and Neural Lineage Commitment

(2014) Nianwei Lin et al.   MOLECULAR CELL

Noncoding RNA and its associated proteins as regulatory elements of the immune system

(2014) Martin Turner et al.   NATURE IMMUNOLOGY

Mechanisms of STAT3 activation in the liver of FXR knockout mice

(2013) Guodong Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Genome-wide transcriptome analysis identifies novel gene signatures implicated in human chronic liver disease

(2013) Rana L. Smalling et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Long Noncoding RNAs: Past, Present, and Future

(2013) J. T. Y. Kung et al.   GENETICS

MicroRNA-433 Inhibits Liver Cancer Cell Migration by Repressing the Protein Expression and Function of cAMP Response Element-binding Protein

(2013) Zhihong Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of the Mitochondrial Localization of the Nuclear Receptor SHP and Regulation of Its Subcellular Distribution by Interaction with Bcl2 and HNF4α

(2013) Yuxia Zhang et al.   PLoS One

Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination

(2013) Je-Hyun Yoon et al.   Nature Communications

Long non-coding RNAgadd7interacts with TDP-43 and regulatesCdk6mRNA decay

(2012) Xuefeng Liu et al.   EMBO JOURNAL

Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice

(2012) Bo Kong et al.   HEPATOLOGY

MEG3 noncoding RNA: a tumor suppressor

(2012) Yunli Zhou et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

LincRNA-p21 Suppresses Target mRNA Translation

(2012) Je-Hyun Yoon et al.   MOLECULAR CELL

Zinc-induced Dnmt1 expression involves antagonism between MTF-1 and nuclear receptor SHP

(2012) Y. Zhang et al.   NUCLEIC ACIDS RESEARCH

Regulation of miR-200c by nuclear receptors PPARα, LRH-1 and SHP

(2011) Yuxia Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA

(2011) Marcella Cesana et al.   CELL

Nuclear receptor SHP inhibition of Dnmt1 expression via ERRγ

(2011) Yuxia Zhang et al.   FEBS LETTERS

Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes

(2011) Elaine Studer et al.   HEPATOLOGY

Diurnal Regulation of the Early Growth Response 1 (Egr-1) Protein Expression by Hepatocyte Nuclear Factor 4α (HNF4α) and Small Heterodimer Partner (SHP) Cross-talk in Liver Fibrosis

(2011) Yuxia Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-coding RNAs in human disease

(2011) Manel Esteller   NATURE REVIEWS GENETICS

Overexpression of nuclear receptor SHP in adipose tissues affects diet-induced obesity and adaptive thermogenesis

(2010) Imene Tabbi-Anneni et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Novel Polymorphisms of Nuclear Receptor SHP Associated with Functional and Structural Changes

(2010) Taofeng Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Receptor SHP, a Death Receptor That Targets Mitochondria, Induces Apoptosis and Inhibits Tumor Growth

(2010) Y. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer

(2010) Jiayi Wang et al.   NUCLEIC ACIDS RESEARCH

Bile acids: regulation of synthesis

(2009) John Y. L. Chiang   JOURNAL OF LIPID RESEARCH

Multiple roles for polypyrimidine tract binding (PTB) proteins in trypanosome RNA metabolism

(2009) M. Z. Stern et al.   RNA

Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein

(2008) Kirsty Sawicka et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Selective Loss ofMEG3Expression and Intergenic Differentially Methylated Region Hypermethylation in theMEG3/DLK1Locus in Human Clinically Nonfunctioning Pituitary Adenomas

(2008) Roger Gejman et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM