H19 potentiates let-7 family expression through reducing PTBP1 binding to their precursors in cholestasis

Post-Translational Modifications in Polypyrimidine Tract Binding Proteins PTBP1 and PTBP2

(2018) Jeffrey M. Pina et al.   BIOCHEMISTRY

The cholangiocyte primary cilium in health and disease

(2018) Adrian P. Mansini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cholangiocyte-derived exosomal long noncoding RNA H19 promotes cholestatic liver injury in mouse and humans

(2018) Xiaojiaoyang Li et al.   HEPATOLOGY

Loss of PDK4 switches the hepatic NF-κB/TNF pathway from pro-survival to pro-apoptosis

(2018) Jianguo Wu et al.   HEPATOLOGY

Long noncoding RNA H19 interacts with polypyrimidine tract-binding protein 1 to reprogram hepatic lipid homeostasis

(2018) Chune Liu et al.   HEPATOLOGY

H19 promotes cholestatic liver fibrosis by preventing ZEB1-mediated inhibition of epithelial cell adhesion molecule

(2017) Yongfeng Song et al.   HEPATOLOGY

The Interplay of LncRNA-H19 and Its Binding Partners in Physiological Process and Gastric Carcinogenesis

(2017) Li Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bile acids and their receptors

(2017) Emmanuelle Martinot et al.   MOLECULAR ASPECTS OF MEDICINE

HMGA2, a driver of inflammation, is associated with hypermethylation in acute liver injury

(2017) Huimin Huang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Lin28 and let-7: roles and regulation in liver diseases

(2016) Kelly McDaniel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Long noncoding RNA MEG3 induces cholestatic liver injury by interaction with PTBP1 to facilitate shp mRNA decay

(2016) Li Zhang et al.   HEPATOLOGY

Pyruvate Dehydrogenase Kinase 4 Deficiency Results in Expedited Cellular Proliferation through E2F1-Mediated Increase of Cyclins

(2016) Jonathan Choiniere et al.   MOLECULAR PHARMACOLOGY

Arsenic silences hepatic PDK4 expression through activation of histone H3K9 methylatransferase G9a

(2016) Xi Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Bcl2 is a critical regulator of bile acid homeostasis by dictating Shp and lncRNA H19 function

(2016) Yuxia Zhang et al.   Scientific Reports

Small heterodimer partner/neuronal PAS domain protein 2 axis regulates the oscillation of liver lipid metabolism

(2015) Sang Min Lee et al.   HEPATOLOGY

The H19 Long non-coding RNA in cancer initiation, progression and metastasis – a proposed unifying theory

(2015) Eli Raveh et al.   Molecular Cancer

Human polypyrimidine tract-binding protein interacts with mitochondrial tRNAThrin the cytosol

(2015) Aline Marnef et al.   NUCLEIC ACIDS RESEARCH

MicroRNAs and Benign Biliary Tract Diseases

(2015) Steven O'Hara et al.   SEMINARS IN LIVER DISEASE

Biogenesis and regulation of the let-7 miRNAs and their functional implications

(2015) Hosuk Lee et al.   Protein & Cell

Secretin Stimulates Biliary Cell Proliferation by Regulating Expression of MicroRNA 125b and MicroRNA let7a in Mice

(2014) Shannon Glaser et al.   GASTROENTEROLOGY

E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network

(2014) Yuxia Zhang et al.   HEPATOLOGY

Therapeutic targeting of microRNAs: current status and future challenges

(2014) Zhonghan Li et al.   NATURE REVIEWS DRUG DISCOVERY

The H19/let-7 double-negative feedback loop contributes to glucose metabolism in muscle cells

(2014) Yuan Gao et al.   NUCLEIC ACIDS RESEARCH

RNA-Binding Protein PTB and MicroRNA-221 Coregulate AdipoR1 Translation and Adiponectin Signaling

(2013) Y. Lustig et al.   DIABETES

MicroRNA-433 Inhibits Liver Cancer Cell Migration by Repressing the Protein Expression and Function of cAMP Response Element-binding Protein

(2013) Zhihong Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Imprinted H19 LncRNA Antagonizes Let-7 MicroRNAs

(2013) Amanda N. Kallen et al.   MOLECULAR CELL

Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs

(2013) D. Ustianenko et al.   RNA

The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r

(2012) Andrew Keniry et al.   NATURE CELL BIOLOGY

Zinc-induced Dnmt1 expression involves antagonism between MTF-1 and nuclear receptor SHP

(2012) Y. Zhang et al.   NUCLEIC ACIDS RESEARCH

Polypyrimidine Tract Binding Protein (hnRNP I) Is Possibly a Conserved Modulator of miRNA-Mediated Gene Regulation

(2012) Bart Engels et al.   PLoS One

Lin28A and Lin28B Inhibit let-7 MicroRNA Biogenesis by Distinct Mechanisms

(2011) Elena Piskounova et al.   CELL

The Lin28/let-7 Axis Regulates Glucose Metabolism

(2011) Hao Zhu et al.   CELL

Analysis of the host microRNA response toSalmonellauncovers the control of major cytokines by thelet-7family

(2011) Leon N Schulte et al.   EMBO JOURNAL

Diurnal Regulation of the Early Growth Response 1 (Egr-1) Protein Expression by Hepatocyte Nuclear Factor 4α (HNF4α) and Small Heterodimer Partner (SHP) Cross-talk in Liver Fibrosis

(2011) Yuxia Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of MicroRNA let-7i Depresses Maturation and Functional State of Dendritic Cells in Response to Lipopolysaccharide Stimulation via Targeting Suppressor of Cytokine Signaling 1

(2011) M. Zhang et al.   JOURNAL OF IMMUNOLOGY

Polypyrimidine Tract-Binding Protein 2 Binds to Selective, Intronic Messenger RNA and MicroRNA Targets in the Mouse Testis

(2010) Mingang Xu et al.   BIOLOGY OF REPRODUCTION

Novel Polymorphisms of Nuclear Receptor SHP Associated with Functional and Structural Changes

(2010) Taofeng Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3

(2010) Yu Wang et al.   JOURNAL OF HEPATOLOGY

Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis

(2010) Gracjan Michlewski et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Primary biliary cirrhosis is associated with altered hepatic microRNA expression

(2009) Kerstien A. Padgett et al.   JOURNAL OF AUTOIMMUNITY

Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein

(2008) Kirsty Sawicka et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Epigenetic mutations of the imprinted IGF2-H19 domain in Silver-Russell syndrome (SRS): results from a large cohort of patients with SRS and SRS-like phenotypes

(2008) D Bartholdi et al.   JOURNAL OF MEDICAL GENETICS

Lin28 Mediates the Terminal Uridylation of let-7 Precursor MicroRNA

(2008) Inha Heo et al.   MOLECULAR CELL