Vertebrate Sensory Ganglia: Common and Divergent Features of the Transcriptional Programs Generating Their Functional Specialization

Loss of bhlha9 Impairs Thermotaxis and Formalin-Evoked Pain in a Sexually Dimorphic Manner

(2020) Manon Bohic et al.   Cell Reports

Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates

(2020) Louis Faure et al.   Nature Communications

The Emerging Role of Cranial Nerves in Shaping Craniofacial Development

(2019) Sonia Sudiwala et al.   GENESIS

Non-trigeminal nociceptive innervation of the posterior dura: implications to occipital headache

(2019) Rodrigo Noseda et al.   JOURNAL OF NEUROSCIENCE

Schwann Cell Precursors; Multipotent Glial Cells in Embryonic Nerves

(2019) Kristjan R. Jessen et al.   Frontiers in Molecular Neuroscience

PRDM12 Is Required for Initiation of the Nociceptive Neuron Lineage during Neurogenesis

(2019) Luca Bartesaghi et al.   Cell Reports

Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA

(2019) Simon Desiderio et al.   Cell Reports

A Cross-Species Analysis Reveals a General Role for Piezo2 in Mechanosensory Specialization of Trigeminal Ganglia from Tactile Specialist Birds

(2019) Eve R. Schneider et al.   Cell Reports

TrkB expression and dependence divides gustatory neurons into three subpopulations

(2019) Jennifer Rios-Pilier et al.   Neural Development

Pou4f1 defines a subgroup of Type I spiral ganglion neurons and is necessary for normal inner hair cell presynaptic Ca2+ signaling

(2019) Hanna E Sherrill et al.   JOURNAL OF NEUROSCIENCE

Extending the phenotype of MiTES: five new cases in three families with PRDM12 mutations

(2019) Arun C. Inamadar et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Proneural factors Ascl1 and Neurog2 contribute to neuronal subtype identities by establishing distinct chromatin landscapes

(2019) Begüm Aydin et al.   NATURE NEUROSCIENCE

The Role of Voltage-Gated Sodium Channels in Pain Signaling

(2019) David L. Bennett et al.   PHYSIOLOGICAL REVIEWS

An Atlas of Vagal Sensory Neurons and Their Molecular Specialization

(2019) Jussi Kupari et al.   Cell Reports

Differences between dorsal root and trigeminal ganglion nociceptors in mice revealed by translational profiling

(2019) Salim Megat et al.   JOURNAL OF NEUROSCIENCE

Spatiotemporal structure of cell fate decisions in murine neural crest

(2019) Ruslan Soldatov et al.   SCIENCE

Human Dorsal Root Ganglia

(2019) Rainer Viktor Haberberger et al.   Frontiers in Cellular Neuroscience

RUNX transcription factors: orchestrators of development

(2019) Renaud Mevel et al.   DEVELOPMENT

Muscle-selective RUNX3 dependence of sensorimotor circuit development

(2019) Yiqiao Wang et al.   DEVELOPMENT

Specialized cutaneous Schwann cells initiate pain sensation

(2019) Hind Abdo et al.   SCIENCE

Taste bud formation depends on taste nerves

(2019) Di Fan et al.   eLife

Sour Sensing from the Tongue to the Brain

(2019) Jin Zhang et al.   CELL

Stereotyped transcriptomic transformation of somatosensory neurons in response to injury

(2019) Minh Q Nguyen et al.   eLife

Neurog2 Deficiency Uncovers a Critical Period of Cell Fate Plasticity and Vulnerability among Neural-Crest-Derived Somatosensory Progenitors

(2019) Stéphanie Ventéo et al.   Cell Reports

The Cochlear Spiral Ganglion Neurons: The Auditory Portion of the VIII Nerve

(2018) Francisco Carricondo et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Mid-face Toddler Excoriation Syndrome (MiTES) can be caused by autosomal recessive biallelic mutations in a gene for congenital insensitivity to pain, PRDM12

(2018) C. Moss et al.   BRITISH JOURNAL OF DERMATOLOGY

All in the family: proneural bHLH genes and neuronal diversity

(2018) Nicholas E. Baker et al.   DEVELOPMENT

Schwann cell precursor: a neural crest cell in disguise?

(2018) Alessandro Furlan et al.   DEVELOPMENTAL BIOLOGY

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells

(2018) Minchul Kim et al.   GENES & DEVELOPMENT

Single-cell RNAseq reveals seven classes of colonic sensory neuron

(2018) James R F Hockley et al.   GUT

A Short History of Nearly Every Sense—The Evolutionary History of Vertebrate Sensory Cell Types

(2018) Gerhard Schlosser   INTEGRATIVE AND COMPARATIVE BIOLOGY

Comparative transcriptome profiling of the human and mouse dorsal root ganglia

(2018) Pradipta Ray et al.   PAIN

TAFA4 Reverses Mechanical Allodynia through Activation of GABAergic Transmission and Microglial Process Retraction

(2018) Charline Kambrun et al.   Cell Reports

Molecular Architecture of the Mouse Nervous System

(2018) Amit Zeisel et al.   CELL

Hair Cell Mechanotransduction Regulates Spontaneous Activity and Spiral Ganglion Subtype Specification in the Auditory System

(2018) Shuohao Sun et al.   CELL

Sensory Neuron Diversity in the Inner Ear Is Shaped by Activity

(2018) Brikha R. Shrestha et al.   CELL

Termination of cell-type specification gene programs by the miR-183 cluster determines the population sizes of low-threshold mechanosensitive neurons

(2018) Changgeng Peng et al.   DEVELOPMENT

Neural Sensing of Organ Volume

(2018) Benjamin D. Umans et al.   TRENDS IN NEUROSCIENCES

The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice

(2018) Swetha E. Murthy et al.   Science Translational Medicine

The Enteric Network: Interactions between the Immune and Nervous Systems of the Gut

(2017) Bryan B. Yoo et al.   IMMUNITY

The transcription factor Phox2b distinguishes between oral and non-oral sensory neurons in the geniculate ganglion

(2017) Lisa Ohman-Gault et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Hierarchical Specification of Pruriceptors by Runt-Domain Transcription Factor Runx1

(2017) Lu Qi et al.   JOURNAL OF NEUROSCIENCE

Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries

(2017) Valentina Boeva et al.   NATURE GENETICS

Piezos thrive under pressure: mechanically activated ion channels in health and disease

(2017) Swetha E. Murthy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Human vs. Mouse Nociceptors – Similarities and Differences

(2017) Charlotte Rostock et al.   NEUROSCIENCE

Distinct and common expression of receptors for inflammatory mediators in vagal nodose versus jugular capsaicin-sensitive/TRPV1-positive neurons detected by low input RNA sequencing

(2017) Jingya Wang et al.   PLoS One

Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest

(2017) Isabel Espinosa-Medina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biphasic functions for the GDNF-Ret signaling pathway in chemosensory neuron development and diversification

(2017) Christopher R. Donnelly et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p75 Is Required for the Establishment of Postnatal Sensory Neuron Diversity by Potentiating Ret Signaling

(2017) Zhijiang Chen et al.   Cell Reports

An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis

(2017) Haoran Zhang et al.   eLife

The Molecular Fingerprint of Dorsal Root and Trigeminal Ganglion Neurons

(2017) Douglas M. Lopes et al.   Frontiers in Molecular Neuroscience

Sox10 contributes to the balance of fate choice in dorsal root ganglion progenitors

(2017) Mariana Delfino-Machín et al.   PLoS One

Diversity amongst trigeminal neurons revealed by high throughput single cell sequencing

(2017) Minh Q. Nguyen et al.   PLoS One

Sensory Neurons that Detect Stretch and Nutrients in the Digestive System

(2016) Erika K. Williams et al.   CELL

Making sense out of spinal cord somatosensory development

(2016) Helen C. Lai et al.   DEVELOPMENT

The mouse Foxi3 transcription factor is necessary for the development of posterior placodes

(2016) Onur Birol et al.   DEVELOPMENTAL BIOLOGY

An ensemble of regulatory elements controls Runx3 spatiotemporal expression in subsets of dorsal root ganglia proprioceptive neurons

(2016) Elena Appel et al.   GENES & DEVELOPMENT

Identification of molecular signatures specific for distinct cranial sensory ganglia in the developing chick

(2016) Cedric Patthey et al.   Neural Development

The sacral autonomic outflow is sympathetic

(2016) I. Espinosa-Medina et al.   SCIENCE

Dissecting the pre-placodal transcriptome to reveal presumptive direct targets of Six1 and Eya1 in cranial placodes

(2016) Nick Riddiford et al.   eLife

Vagal Sensory Neuron Subtypes that Differentially Control Breathing

(2015) Rui B. Chang et al.   CELL

The evolutionarily conserved transcription factor PRDM12 controls sensory neuron development and pain perception

(2015) Vanja Nagy et al.   CELL CYCLE

Somatosensory neuron types identified by high-coverage single-cell RNA-sequencing and functional heterogeneity

(2015) Chang-Lin Li et al.   CELL RESEARCH

The melanocyte lineage in development and disease

(2015) R. L. Mort et al.   DEVELOPMENT

Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus

(2015) Aurore Thélie et al.   DEVELOPMENT

Establishing neural crest identity: a gene regulatory recipe

(2015) M. Simoes-Costa et al.   DEVELOPMENT

The requirement of histone modification by PRDM12 and Kdm4a for the development of pre-placodal ectoderm and neural crest in Xenopus

(2015) Shinya Matsukawa et al.   DEVELOPMENTAL BIOLOGY

Zeb Family Members and Boundary Cap Cells Underlie Developmental Plasticity of Sensory Nociceptive Neurons

(2015) David Ohayon et al.   DEVELOPMENTAL CELL

NeuroD1 reprograms chromatin and transcription factor landscapes to induce the neuronal program

(2015) A. Pataskar et al.   EMBO JOURNAL

Surgically implanted and non-invasive vagus nerve stimulation: a review of efficacy, safety and tolerability

(2015) E. Ben-Menachem et al.   EUROPEAN JOURNAL OF NEUROLOGY

Transcriptional control of neural crest specification into peripheral glia

(2015) Claire Jacob   GLIA

Dynamic expression of transcription factor Brn3b during mouse cranial nerve development

(2015) Szilard Sajgo et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Incoherent Feed-Forward Regulatory Loops Control Segregation of C-Mechanoreceptors, Nociceptors, and Pruriceptors

(2015) S. Lou et al.   JOURNAL OF NEUROSCIENCE

Transcriptional regulator PRDM12 is essential for human pain perception

(2015) Ya-Chun Chen et al.   NATURE GENETICS

Piezo2 is the principal mechanotransduction channel for proprioception

(2015) Seung-Hyun Woo et al.   NATURE NEUROSCIENCE

Extrinsic and intrinsic signals converge on the Runx1/CBFβ transcription factor for nonpeptidergic nociceptor maturation

(2015) Siyi Huang et al.   eLife

Six1 is a key regulator of the developmental and evolutionary architecture of sensory neurons in craniates

(2014) Hiroshi Yajima et al.   BMC BIOLOGY

Merkel Cells Transduce and Encode Tactile Stimuli to Drive Aβ-Afferent Impulses

(2014) Ryo Ikeda et al.   CELL

Establishing the pre-placodal region and breaking it into placodes with distinct identities

(2014) Jean-Pierre Saint-Jeannet et al.   DEVELOPMENTAL BIOLOGY

The evolutionary history of vertebrate cranial placodes – I: Cell type evolution

(2014) Cedric Patthey et al.   DEVELOPMENTAL BIOLOGY

Neural crest and placode interaction during the development of the cranial sensory system

(2014) Ben Steventon et al.   DEVELOPMENTAL BIOLOGY

Molecular Signatures of Mouse TRPV1-Lineage Neurons Revealed by RNA-Seq Transcriptome Analysis

(2014) Samridhi C. Goswami et al.   JOURNAL OF PAIN

Piezo2 is the major transducer of mechanical forces for touch sensation in mice

(2014) Sanjeev S. Ranade et al.   NATURE

Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing

(2014) Dmitry Usoskin et al.   NATURE NEUROSCIENCE

TNF-α/TNFR1 Signaling Is Required for the Development and Function of Primary Nociceptors

(2014) Michael A. Wheeler et al.   NEURON

The gentle touch receptors of mammalian skin

(2014) A. Zimmerman et al.   SCIENCE

Parasympathetic ganglia derive from Schwann cell precursors

(2014) I. Espinosa-Medina et al.   SCIENCE

Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity

(2014) Isaac M Chiu et al.   eLife

Early embryonic specification of vertebrate cranial placodes

(2014) Gerhard Schlosser   Wiley Interdisciplinary Reviews-Developmental Biology

Defining the nociceptor transcriptome

(2014) Matthew Thakur et al.   Frontiers in Molecular Neuroscience

A boy with homozygous microdeletion of NEUROG1 presents with a congenital cranial dysinnervation disorder [Moebius syndrome variant]

(2013) Julia C Schröder et al.   Behavioral and Brain Functions

Prdm12 Is Induced by Retinoic Acid and Exhibits Anti-proliferative Properties through the Cell Cycle Modulation of P19 Embryonic Carcinoma Cells

(2013) Chia-Ming Yang et al.   CELL STRUCTURE AND FUNCTION

Sox proteins: regulators of cell fate specification and differentiation

(2013) Y. Kamachi et al.   DEVELOPMENT

Signaling mechanisms controlling cranial placode neurogenesis and delamination

(2013) Rhonda N.T. Lassiter et al.   DEVELOPMENTAL BIOLOGY

Coexpression of Runx1 and Runx3 in mechanoreceptive dorsal root ganglion neurons

(2013) Masaaki Yoshikawa et al.   Developmental Neurobiology

The transcription factor Hmx1 and growth factor receptor activities control sympathetic neurons diversification

(2013) Alessandro Furlan et al.   EMBO JOURNAL

GATA3 controls the specification of prosensory domain and neuronal survival in the mouse cochlea

(2013) Xiong-jian Luo et al.   HUMAN MOLECULAR GENETICS

Runx1 Controls Terminal Morphology and Mechanosensitivity of VGLUT3-expressing C-Mechanoreceptors

(2013) S. Lou et al.   JOURNAL OF NEUROSCIENCE

The Star-Nosed Mole Reveals Clues to the Molecular Basis of Mammalian Touch

(2013) Kristin A. Gerhold et al.   PLoS One

Comprehensive RNA-Seq Expression Analysis of Sensory Ganglia with a Focus on Ion Channels and GPCRs in Trigeminal Ganglia

(2013) Stavros Manteniotis et al.   PLoS One

Genetic Control of the Segregation of Pain-Related Sensory Neurons Innervating the Cutaneous versus Deep Tissues

(2013) Fu-Chia Yang et al.   Cell Reports

TAFA4, a Chemokine-like Protein, Modulates Injury-Induced Mechanical and Chemical Pain Hypersensitivity in Mice

(2013) Marie-Claire Delfini et al.   Cell Reports

Early Development of the Vertebrate Inner Ear

(2012) MARTA MagariÑos et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear

(2012) M. Ahmed et al.   DEVELOPMENT

The Prdm family: expanding roles in stem cells and development

(2012) T. Hohenauer et al.   DEVELOPMENT

Hmx1 is required for the normal development of somatosensory neurons in the geniculate ganglion

(2012) Lely A. Quina et al.   DEVELOPMENTAL BIOLOGY

Neural crest delamination and migration: From epithelium-to-mesenchyme transition to collective cell migration

(2012) Eric Theveneau et al.   DEVELOPMENTAL BIOLOGY

The peripheral sensory nervous system in the vertebrate head: A gene regulatory perspective

(2012) Timothy Grocott et al.   DEVELOPMENTAL BIOLOGY

Brn3a/Pou4f1 regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord

(2012) Min Zou et al.   DEVELOPMENTAL BIOLOGY

Positional differences of axon growth rates between sensory neurons encoded by runx3

(2012) Francois Lallemend et al.   EMBO JOURNAL

Autonomic neurocristopathy-associated mutations in PHOX2B dysregulate Sox10 expression

(2012) Mayumi Nagashimada et al.   JOURNAL OF CLINICAL INVESTIGATION

Combinatorial Expression of Brn3 Transcription Factors in Somatosensory Neurons: Genetic and Morphologic Analysis

(2012) T. C. Badea et al.   JOURNAL OF NEUROSCIENCE

c-Maf Is Required for the Development of Dorsal Horn Laminae III/IV Neurons and Mechanoreceptive DRG Axon Projections

(2012) J. Hu et al.   JOURNAL OF NEUROSCIENCE

Tlx3 and Runx1 Act in Combination to Coordinate the Development of a Cohort of Nociceptors, Thermoceptors, and Pruriceptors

(2012) C. Lopes et al.   JOURNAL OF NEUROSCIENCE

The Transcription Factor c-Maf Controls Touch Receptor Development and Function

(2012) H. Wende et al.   SCIENCE

Molecular interactions underlying the specification of sensory neurons

(2012) Francois Lallemend et al.   TRENDS IN NEUROSCIENCES

Dual embryonic origin of the mammalian otic vesicle forming the inner ear

(2011) L. Freyer et al.   DEVELOPMENT

Differential contribution ofNeurog1andNeurog2on the formation of cranial ganglia along the anterior-posterior axis

(2011) Masumi Takano-Maruyama et al.   DEVELOPMENTAL DYNAMICS

Dependence on the transcription factor Shox2 for specification of sensory neurons conveying discriminative touch

(2011) Hind Abdo et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Brn3a and Islet1 Act Epistatically to Regulate the Gene Expression Program of Sensory Differentiation

(2011) I. M. Dykes et al.   JOURNAL OF NEUROSCIENCE

Transcription Factor Short Stature Homeobox 2 Is Required for Proper Development of Tropomyosin-Related Kinase B-Expressing Mechanosensory Neurons

(2011) A. Scott et al.   JOURNAL OF NEUROSCIENCE

Developmental Profiling of Spiral Ganglion Neurons Reveals Insights into Auditory Circuit Assembly

(2011) C. C. Lu et al.   JOURNAL OF NEUROSCIENCE

Isl1 Is required for multiple aspects of motor neuron development

(2011) Xingqun Liang et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Phenotypic Switching of Nonpeptidergic Cutaneous Sensory Neurons following Peripheral Nerve Injury

(2011) Ting Wang et al.   PLoS One

Homeoprotein Phox2b commands a somatic-to-visceral switch in cranial sensory pathways

(2011) F. D'Autreaux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ongoing roles of Phox2 homeodomain transcription factors during neuronal differentiation

(2010) E. Coppola et al.   DEVELOPMENT

Homozygous Mutations in NEUROD1 Are Responsible for a Novel Syndrome of Permanent Neonatal Diabetes and Neurological Abnormalities

(2010) O. Rubio-Cabezas et al.   DIABETES

Glial but not neuronal development in the cochleo-vestibular ganglion requires Sox10

(2010) Ingrid Breuskin et al.   JOURNAL OF NEUROCHEMISTRY

Characterization of Two Runx1-Dependent Nociceptor Differentiation Programs Necessary for Inflammatory versus Neuropathic Pain

(2010) Omar Abdel Samad et al.   Molecular Pain

Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation

(2010) Iain M Dykes et al.   Neural Development

Canal Cristae Growth and Fiber Extension to the Outer Hair Cells of the Mouse Ear Require Prox1 Activity

(2010) Bernd Fritzsch et al.   PLoS One

Epibranchial ganglia orchestrate the development of the cranial neurogenic crest

(2010) E. Coppola et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brn3a regulates the transition from neurogenesis to terminal differentiation and represses non-neural gene expression in the trigeminal ganglion

(2009) Jason Lanier et al.   DEVELOPMENTAL DYNAMICS

Runx3 is required for the specification of TrkC-expressing mechanoreceptive trigeminal ganglion neurons

(2009) Kouji Senzaki et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Molecular Identification of Rapidly Adapting Mechanoreceptors and Their Developmental Dependence on Ret Signaling

(2009) Wenqin Luo et al.   NEURON

Low-Threshold Mechanoreceptor Subtypes Selectively Express MafA and Are Specified by Ret Signaling

(2009) Steeve Bourane et al.   NEURON

Development, plasticity and modulation of visceral afferents

(2008) Julie A. Christianson et al.   BRAIN RESEARCH REVIEWS

Dynamic regulation of the expression of neurotrophin receptors by Runx3

(2008) S. Nakamura et al.   DEVELOPMENT

A central role for Islet1 in sensory neuron development linking sensory and spinal gene regulatory programs

(2008) Yunfu Sun et al.   NATURE NEUROSCIENCE

Transient receptor potential channels: targeting pain at the source

(2008) Ardem Patapoutian et al.   NATURE REVIEWS DRUG DISCOVERY

Prdm Proto-Oncogene Transcription Factor Family Expression and Interaction with the Notch-Hes Pathway in Mouse Neurogenesis

(2008) Emi Kinameri et al.   PLoS One

Tlx3 exerts context-dependent transcriptional regulation and promotes neuronal differentiation from embryonic stem cells

(2008) T. Kondo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A human mutation in Phox2b causes lack of CO2 chemosensitivity, fatal central apnea, and specific loss of parafacial neurons

(2008) V. Dubreuil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA