Comprehensive RNA-Seq Expression Analysis of Sensory Ganglia with a Focus on Ion Channels and GPCRs in Trigeminal Ganglia

Decreased expression of the satiety signal receptor CCKAR is responsible for increased growth and body weight during the domestication of chickens

(2013) Ian C. Dunn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Systematic and quantitative mRNA expression analysis of TRP channel genes at the single trigeminal and dorsal root ganglion level in mouse

(2013) Ine Vandewauw et al.   BMC NEUROSCIENCE

Genetic identification of C fibres that detect massage-like stroking of hairy skin in vivo

(2013) Sophia Vrontou et al.   NATURE

Kv1.1 Channels Act as Mechanical Brake in the Senses of Touch and Pain

(2013) Jizhe Hao et al.   NEURON

Expression Profile of Ectopic Olfactory Receptors Determined by Deep Sequencing

(2013) Caroline Flegel et al.   PLoS One

Pirt functions as an endogenous regulator of TRPM8

(2013) Zongxiang Tang et al.   Nature Communications

Application of array comparative genomic hybridization in 102 patients with epilepsy and additional neurodevelopmental disorders

(2012) Magdalena Bartnik et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Link Between Pain and Olfaction in an Inherited Sodium Channelopathy

(2012) Frank Zufall et al.   ARCHIVES OF NEUROLOGY

Expression patterns of anoctamin 1 and anoctamin 2 chloride channels in the mammalian nose

(2012) Kristin Dauner et al.   CELL AND TISSUE RESEARCH

Peripheral hyperpolarization-activated cyclic nucleotide-gated channels contribute to inflammation-induced hypersensitivity of the rat temporomandibular joint

(2012) R.J. Hatch et al.   EUROPEAN JOURNAL OF PAIN

P2X7receptor in the trigeminal sensory nuclear complex contributes to tactile allodynia/hyperalgesia following trigeminal nerve injury

(2012) G. Ito et al.   EUROPEAN JOURNAL OF PAIN

Transcriptomes of Mouse Olfactory Epithelium Reveal Sexual Differences in Odorant Detection

(2012) Meng-Shin Shiao et al.   Genome Biology and Evolution

Two Mechanisms Involved in Trigeminal CGRP Release: Implications for Migraine Treatment

(2012) Paul L. Durham et al.   HEADACHE

General Olfactory Sensitivity Database (GOSdb): Candidate Genes and their Genomic Variations

(2012) Ifat Keydar et al.   HUMAN MUTATION

Inhibition of 5-HT3 receptors-activated currents by cannabinoids in rat trigeminal ganglion neurons

(2012) Bo Shi et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Study of autosomal recessive osteogenesis imperfecta in Arabia reveals a novel locus defined byTMEM38Bmutation

(2012) Ranad Shaheen et al.   JOURNAL OF MEDICAL GENETICS

Sensory Neuron Downregulation of the Kv9.1 Potassium Channel Subunit Mediates Neuropathic Pain following Nerve Injury

(2012) C. Tsantoulas et al.   JOURNAL OF NEUROSCIENCE

A-type K+channels encoded by Kv4.2, Kv4.3 and Kv1.4 differentially regulate intrinsic excitability of cortical pyramidal neurons

(2012) Yarimar Carrasquillo et al.   JOURNAL OF PHYSIOLOGY-LONDON

GPR56 and the Developing Cerebral Cortex: Cells, Matrix, and Neuronal Migration

(2012) Kathleen Singer et al.   MOLECULAR NEUROBIOLOGY

Progesterone Produces Antinociceptive and Neuroprotective Effects in Rats with Microinjected Lysophosphatidic Acid in the Trigeminal Nerve Root

(2012) Min Ji Kim et al.   Molecular Pain

Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity

(2012) Robert E Sorge et al.   NATURE MEDICINE

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Mutations in potassium channel KCNT1—a novel driver of epilepsy pathogenesis

(2012) Katie Kingwell   Nature Reviews Neurology

Expression of P2X1 and P2X4 receptors in rat trigeminal ganglion neurons

(2012) Hidetaka Kuroda et al.   NEUROREPORT

Enhanced SCN7A/Nax expression contributes to bone cancer pain by increasing excitability of neurons in dorsal root ganglion

(2012) C.B. Ke et al.   NEUROSCIENCE

Transcriptional expression of voltage-gated Na+ and voltage-independent K+ channels in the developing rat superficial dorsal horn

(2012) M.L. Blankenship et al.   NEUROSCIENCE

The Schizophrenia-Associated Kv11.1-3.1 Isoform Results in Reduced Current Accumulation during Repetitive Brief Depolarizations

(2012) Juliane Heide et al.   PLoS One

Trigeminal Ganglion Neurons of Mice Show Intracellular Chloride Accumulation and Chloride-Dependent Amplification of Capsaicin-Induced Responses

(2012) Nicole Schöbel et al.   PLoS One

Dynamic modulation of ANO1/TMEM16A HCO3- permeability by Ca2+/calmodulin

(2012) J. Jung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammatory Signals Enhance Piezo2-Mediated Mechanosensitive Currents

(2012) Adrienne E. Dubin et al.   Cell Reports

TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells

(2012) K. Quick et al.   Open Biology

Increased Expression of Sodium Channel Subunit Nav1.1 in the Injured Dorsal Root Ganglion After Peripheral Nerve Injury

(2011) Wei Wang et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Orexin Receptors: Pharmacology and Therapeutic Opportunities

(2011) Thomas E. Scammell et al.   Annual Review of Pharmacology and Toxicology

Molecular evolution of a chordate specific family of G protein-coupled receptors

(2011) Stefan Kurtenbach et al.   BMC EVOLUTIONARY BIOLOGY

Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to treatment in patients with major depressive disorder

(2011) Alberto Chiesa et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Anoctamin 2/TMEM16B: a calcium-activated chloride channel in olfactory transduction

(2011) Simone Pifferi et al.   EXPERIMENTAL PHYSIOLOGY

Chemosensory Ca2+Dynamics Correlate with Diverse Behavioral Phenotypes in Human Sperm

(2011) Thomas Veitinger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Up-regulation of Cavβ3Subunit in Primary Sensory Neurons Increases Voltage-activated Ca2+Channel Activity and Nociceptive Input in Neuropathic Pain

(2011) Li Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Brain Expression of Kv3 Subunits During Development, Adulthood and Aging and in a Murine Model of Alzheimer’s Disease

(2011) Enrica Boda et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors

(2011) Katherine C. Murray et al.   JOURNAL OF NEUROPHYSIOLOGY

An Autocrine Neuronal Interleukin-6 Loop Mediates Chloride Accumulation and NKCC1 Phosphorylation in Axotomized Sensory Neurons

(2011) S. Pieraut et al.   JOURNAL OF NEUROSCIENCE

Oncostatin M Induces Heat Hypersensitivity by gp130-Dependent Sensitization of TRPV1 in Sensory Neurons

(2011) Michiel Langeslag et al.   Molecular Pain

Potassium Channels as a Potential Therapeutic Target for Trigeminal Neuropathic and Inflammatory Pain

(2011) Mamoru Takeda et al.   Molecular Pain

Loss-of-function mutations in sodium channel Nav1.7 cause anosmia

(2011) Jan Weiss et al.   NATURE

Computational methods for transcriptome annotation and quantification using RNA-seq

(2011) Manuel Garber et al.   NATURE METHODS

KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man

(2011) Matthias Heidenreich et al.   NATURE NEUROSCIENCE

Galanin receptor-expressing dorsal horn neurons: Role in nociception

(2011) Laurie L. Lemons et al.   NEUROPEPTIDES

Role of peripheral 5-HT4, 5-HT6, and 5-HT7 receptors in development and maintenance of secondary mechanical allodynia and hyperalgesia

(2011) Beatriz Godínez-Chaparro et al.   PAIN

Pirt, a TRPV1 Modulator, Is Required for Histamine-Dependent and -Independent Itch

(2011) Kush N. Patel et al.   PLoS One

Nasal Chemosensory-Stimulation Evoked Activity Patterns in the Rat Trigeminal Ganglion Visualized by In Vivo Voltage-Sensitive Dye Imaging

(2011) Markus Rothermel et al.   PLoS One

Regulation of Cysteinyl Leukotriene Receptor 2 Expression—A Potential Anti-Tumor Mechanism

(2011) Cecilia Magnusson et al.   PLoS One

Transient receptor potential cation channel, subfamily C, member 5 (TRPC5) is a cold-transducer in the peripheral nervous system

(2011) K. Zimmermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transient receptor potential vanilloid 1 (TRPV1)-expressing neurons

(2011) S.-J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HCN2 Ion Channels Play a Central Role in Inflammatory and Neuropathic Pain

(2011) E. C. Emery et al.   SCIENCE

Sodium Channels in Normal and Pathological Pain

(2010) Sulayman D. Dib-Hajj et al.   Annual Review of Neuroscience

LPA Receptors: Subtypes and Biological Actions

(2010) Ji Woong Choi et al.   Annual Review of Pharmacology and Toxicology

Molecular determination of selectivity of the site 3 modulator (BmK I) to sodium channels in the CNS: a clue to the importance of Nav1.6 in BmK I-induced neuronal hyperexcitability

(2010) Huiqiong He et al.   BIOCHEMICAL JOURNAL

Overexpression of leucine-rich repeat-containing G protein-coupled receptor 5 in colorectal cancer

(2010) Hiroshi Uchida et al.   CANCER SCIENCE

Tmem16b is Specifically Expressed in the Cilia of Olfactory Sensory Neurons

(2010) Sebastian Rasche et al.   CHEMICAL SENSES

Association of thromboxane A2 receptor (TBXA2R) gene polymorphism in patients with aspirin-intolerant acute urticaria

(2010) N. S. Palikhe et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Orexins/Hypocretins: Pain Regulation and Cellular Actions

(2010) Lih-Chu Chiou et al.   CURRENT PHARMACEUTICAL DESIGN

Pain as a channelopathy

(2010) Ramin Raouf et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of Voltage-Gated KCNQ/Kv7 Channels by Anticonvulsant Retigabine Attenuates Mechanical Allodynia of Inflammatory Temporomandibular Joint in Rats

(2010) Wen Xu et al.   Molecular Pain

Aquaporin 1, a Potential Therapeutic Target for Migraine with Aura

(2010) Guang-Yin Xu et al.   Molecular Pain

A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura

(2010) Ronald G Lafrenière et al.   NATURE MEDICINE

G-protein coupled receptor 35 (GPR35) activation and inflammatory pain: Studies on the antinociceptive effects of kynurenic acid and zaprinast

(2010) Cristina Cosi et al.   NEUROPHARMACOLOGY

Dural afferents express acid-sensing ion channels: A role for decreased meningeal pH in migraine headache

(2010) Jin Yan et al.   PAIN

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

(2010) S. F. Traynelis et al.   PHARMACOLOGICAL REVIEWS

Coexistence of up-regulated NMDA receptor 1 and glutamate on nerves, vessels and transformed tenocytes in tendinopathy

(2010) N. Schizas et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Sfrp5 Is an Anti-Inflammatory Adipokine That Modulates Metabolic Dysfunction in Obesity

(2010) N. Ouchi et al.   SCIENCE

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Made for “anchorin”: Kv7.2/7.3 (KCNQ2/KCNQ3) channels and the modulation of neuronal excitability in vertebrate axons

(2010) Edward C. Cooper   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Kv2.1 and silent Kv subunits underlie the delayed rectifier K+ current in cultured small mouse DRG neurons

(2009) Elke Bocksteins et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Molecular and Cellular Mechanisms of Trigeminal Chemosensation

(2009) Kristin A. Gerhold et al.   Annals of the New York Academy of Sciences

Neuropathic Pain: A Maladaptive Response of the Nervous System to Damage

(2009) Michael Costigan et al.   Annual Review of Neuroscience

Antagonism of Human Adiponectin Receptors and Their Membrane Progesterone Receptor Paralogs by TNFα and a Ceramidase Inhibitor

(2009) Brian R. Kupchak et al.   BIOCHEMISTRY

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents

(2009) Tatjana Haitina et al.   BMC GENOMICS

Differential expression of neuronal voltage-gated sodium channel mRNAs during the development of the rat trigeminal ganglion

(2009) Jonas Thun et al.   BRAIN RESEARCH

Chloride regulation in the pain pathway

(2009) Theodore J. Price et al.   BRAIN RESEARCH REVIEWS

Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced Pruritus

(2009) Qin Liu et al.   CELL

Variant Ionotropic Glutamate Receptors as Chemosensory Receptors in Drosophila

(2009) Richard Benton et al.   CELL

Hyperpolarization-activated cyclic-nucleotide gated 4 (HCN4) protein is expressed in a subset of rat dorsal root and trigeminal ganglion neurons

(2009) Hyun-jung Cho et al.   CELL AND TISSUE RESEARCH

Purinergic Receptors and Pain

(2009) Geoffrey Burnstock   CURRENT PHARMACEUTICAL DESIGN

Differential expression of sphingosine-1-phosphate receptors 1-5 in the developing nervous system

(2009) H. Meng et al.   DEVELOPMENTAL DYNAMICS

Patents related to therapeutic activation of KATPand K2Ppotassium channels for neuroprotection: ischemic/hypoxic/anoxic injury and general anesthetics

(2009) Susan IV Judge et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Involvement of Pro-Nociceptive 5-HT2AReceptor in the Pathogenesis of Medication-Overuse Headache

(2009) Weera Supornsilpchai et al.   HEADACHE

Shedding light on DARC: the role of the Duffy antigen/receptor for chemokines in inflammation, infection and malignancy

(2009) K. Horne et al.   INFLAMMATION RESEARCH

Physiological and pathophysiological roles of adiponectin and adiponectin receptors in the integrated regulation of metabolic and cardiovascular diseases

(2009) T Yamauchi et al.   INTERNATIONAL JOURNAL OF OBESITY

Activation of an Olfactory Receptor Inhibits Proliferation of Prostate Cancer Cells

(2009) Eva M. Neuhaus et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emerging Peripheral Receptor Targets for Deep-tissue Craniofacial Pain Therapies

(2009) R. Ambalavanar et al.   JOURNAL OF DENTAL RESEARCH

Mrgprd Enhances Excitability in Specific Populations of Cutaneous Murine Polymodal Nociceptors

(2009) K. K. Rau et al.   JOURNAL OF NEUROSCIENCE

A Key Role for gp130 Expressed on Peripheral Sensory Nerves in Pathological Pain

(2009) M. Andratsch et al.   JOURNAL OF NEUROSCIENCE

Calcium-activated chloride currents in olfactory sensory neurons from mice lacking bestrophin-2

(2009) Simone Pifferi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Inflammation-induced increase in hyperpolarization-activated, cyclic nucleotide-gated channel protein in trigeminal ganglion neurons and the effect of buprenorphine

(2009) H.-J. Cho et al.   NEUROSCIENCE

Immunohistochemical colocalization of TREK-1, TREK-2 and TRAAK with TRP channels in the trigeminal ganglion cells

(2009) Yoshio Yamamoto et al.   NEUROSCIENCE LETTERS

Targeting voltage-gated calcium channels for neuropathic pain management

(2009) Danielle Perret et al.   Neurotherapeutics

Differential regulation of TRP channels in a rat model of neuropathic pain

(2009) Susanne Staaf et al.   PAIN

ANO2 is the cilial calcium-activated chloride channel that may mediate olfactory amplification

(2009) Aaron B. Stephan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Orphan endogenous lipids and orphan GPCRs: A good match

(2009) Heather B. Bradshaw et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Pirt, a Phosphoinositide-Binding Protein, Functions as a Regulatory Subunit of TRPV1

(2008) Andrew Y. Kim et al.   CELL

Expression Cloning of TMEM16A as a Calcium-Activated Chloride Channel Subunit

(2008) Björn Christian Schroeder et al.   CELL

TRPs in Our Senses

(2008) Nils Damann et al.   CURRENT BIOLOGY

RNA-seq: An assessment of technical reproducibility and comparison with gene expression arrays

(2008) J. C. Marioni et al.   GENOME RESEARCH

A high-density association screen of 155 ion transport genes for involvement with common migraine

(2008) Dale R. Nyholt et al.   HUMAN MOLECULAR GENETICS

De novoexpression of Kv6.3 contributes to changes in vascular smooth muscle cell excitability in a hypertensive mice strain

(2008) Alejandro Moreno-Domínguez et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels

(2008) Diana M Bautista et al.   NATURE NEUROSCIENCE

Transient receptor potential channels: targeting pain at the source

(2008) Ardem Patapoutian et al.   NATURE REVIEWS DRUG DISCOVERY

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS

Retigabine, the specific KCNQ channel opener, blocks ectopic discharges in axotomized sensory fibres

(2008) Carolina Roza et al.   PAIN

Activation of interleukin-1β receptor suppresses the voltage-gated potassium currents in the small-diameter trigeminal ganglion neurons following peripheral inflammation

(2008) Mamoru Takeda et al.   PAIN

Voltage-gated calcium channels in chronic pain: emerging role of alternative splicing

(2008) Leigh Anne Swayne et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Heterologous expression of human mPRα, mPRβ and mPRγ in yeast confirms their ability to function as membrane progesterone receptors

(2008) Jessica L. Smith et al.   STEROIDS

Changes in the expression of NaV1.7, NaV1.8 and NaV1.9 in a distinct population of dorsal root ganglia innervating the rat knee joint in a model of chronic inflammatory joint pain

(2007) Iain T. Strickland et al.   EUROPEAN JOURNAL OF PAIN

Modulation of pain transmission by G-protein-coupled receptors

(2007) Hui-Lin Pan et al.   PHARMACOLOGY & THERAPEUTICS