Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Molecular Signatures of Mouse TRPV1-Lineage Neurons Revealed by RNA-Seq Transcriptome Analysis

(2014) Samridhi C. Goswami et al.   JOURNAL OF PAIN

Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors

(2014) Srdjan Maksimovic et al.   NATURE

Piezo2 is required for Merkel-cell mechanotransduction

(2014) Seung-Hyun Woo et al.   NATURE

Single-cell RNA-seq reveals dynamic paracrine control of cellular variation

(2014) Alex K. Shalek et al.   NATURE

Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts

(2014) Brian J Wainger et al.   NATURE NEUROSCIENCE

Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing

(2014) Dmitry Usoskin et al.   NATURE NEUROSCIENCE

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

(2014) A. P. Patel et al.   SCIENCE

Defining the nociceptor transcriptome

(2014) Matthew Thakur et al.   Frontiers in Molecular Neuroscience

TRP Channels and Pain

(2013) David Julius   Annual Review of Cell and Developmental Biology

Analysis of gene expression in wild-type and Notch1 mutant retinal cells by single cell profiling

(2013) Karolina Mizeracka et al.   DEVELOPMENTAL DYNAMICS

Modality-Based Organization of Ascending Somatosensory Axons in the Direct Dorsal Column Pathway

(2013) J. Niu et al.   JOURNAL OF NEUROSCIENCE

 2 -1 Gene Deletion Affects Somatosensory Neuron Function and Delays Mechanical Hypersensitivity in Response to Peripheral Nerve Damage

(2013) R. Patel et al.   JOURNAL OF NEUROSCIENCE

Runx1 Controls Terminal Morphology and Mechanosensitivity of VGLUT3-expressing C-Mechanoreceptors

(2013) S. Lou et al.   JOURNAL OF NEUROSCIENCE

Genetic identification of C fibres that detect massage-like stroking of hairy skin in vivo

(2013) Sophia Vrontou et al.   NATURE

The transcriptional landscape of αβ T cell differentiation

(2013) Michael Mingueneau et al.   NATURE IMMUNOLOGY

The Sensory Neurons of Touch

(2013) Victoria E. Abraira et al.   NEURON

Etv1 Inactivation Reveals Proprioceptor Subclasses that Reflect the Level of NT3 Expression in Muscle Targets

(2013) Joriene C. de Nooij et al.   NEURON

Mapping Neuronal Diversity One Cell at a Time

(2013) H. Wichterle et al.   SCIENCE

The Cells and Circuitry for Itch Responses in Mice

(2013) S. K. Mishra et al.   SCIENCE

Tlx3 and Runx1 Act in Combination to Coordinate the Development of a Cohort of Nociceptors, Thermoceptors, and Pruriceptors

(2012) C. Lopes et al.   JOURNAL OF NEUROSCIENCE

Sensory Neuron Downregulation of the Kv9.1 Potassium Channel Subunit Mediates Neuropathic Pain following Nerve Injury

(2012) C. Tsantoulas et al.   JOURNAL OF NEUROSCIENCE

The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons

(2012) Hawon Cho et al.   NATURE NEUROSCIENCE

Nav1.8 expression is not restricted to nociceptors in mouse peripheral nervous system

(2012) Shannon D. Shields et al.   PAIN

Scaling Proprioceptor Gene Transcription by Retrograde NT3 Signaling

(2012) Jun Lee et al.   PLoS One

The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons

(2011) Lishi Li et al.   CELL

TRPC1 contributes to light-touch sensation and mechanical responses in low-threshold cutaneous sensory neurons

(2011) Sheldon R. Garrison et al.   JOURNAL OF NEUROPHYSIOLOGY

Cell Type-Specific Transcriptomics in the Brain

(2011) B. W. Okaty et al.   JOURNAL OF NEUROSCIENCE

Comprehensive qPCR profiling of gene expression in single neuronal cells

(2011) Ami Citri et al.   Nature Protocols

Sodium Channels in Normal and Pathological Pain

(2010) Sulayman D. Dib-Hajj et al.   Annual Review of Neuroscience

Multiple chronic pain states are associated with a common amino acid–changing allele in KCNS1

(2010) Michael Costigan et al.   BRAIN

A Genome-wide Drosophila Screen for Heat Nociception Identifies α2δ3 as an Evolutionarily Conserved Pain Gene

(2010) G. Gregory Neely et al.   CELL

Nociceptors: the sensors of the pain pathway

(2010) Adrienne E. Dubin et al.   JOURNAL OF CLINICAL INVESTIGATION

Distinct Transcriptomes Define Rostral and Caudal Serotonin Neurons

(2010) C. J. Wylie et al.   JOURNAL OF NEUROSCIENCE

Characterization of Two Runx1-Dependent Nociceptor Differentiation Programs Necessary for Inflammatory versus Neuropathic Pain

(2010) Omar Abdel Samad et al.   Molecular Pain

VGLUT2-Dependent Glutamate Release from Nociceptors Is Required to Sense Pain and Suppress Itch

(2010) Yang Liu et al.   NEURON

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Mrgprd-Expressing Polymodal Nociceptive Neurons Innervate Most Known Classes of Substantia Gelatinosa Neurons

(2009) H. Wang et al.   JOURNAL OF NEUROSCIENCE

Novel Subtype-Specific Genes Identify Distinct Subpopulations of Callosal Projection Neurons

(2009) B. J. Molyneaux et al.   JOURNAL OF NEUROSCIENCE

Transcriptional and Electrophysiological Maturation of Neocortical Fast-Spiking GABAergic Interneurons

(2009) B. W. Okaty et al.   JOURNAL OF NEUROSCIENCE

Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors

(2009) Rebecca P. Seal et al.   NATURE

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain

(2008) B. Abrahamsen et al.   SCIENCE