Role of Wnt Signaling in Adult Hippocampal Neurogenesis in Health and Disease
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Role of Wnt Signaling in Adult Hippocampal Neurogenesis in Health and Disease
Authors
Keywords
-
Journal
Frontiers in Cell and Developmental Biology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-09-16
DOI
10.3389/fcell.2020.00860
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Targeting the Wnt/β-catenin pathway in neurodegenerative diseases: recent approaches and current challenges
- (2020) Annalucia Serafino et al. Expert Opinion on Drug Discovery
- sFRP3 inhibition improves age-related cellular changes in BubR1 progeroid mice
- (2019) Chang Hoon Cho et al. AGING CELL
- Differential changes in the number and morphology of the new neurons after chronic infusion of Wnt7a, Wnt5a and Dkk-1 in the adult hippocampus in vivo
- (2019) Abril Ortiz-Matamoros et al. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
- Valproic Acid Stimulates Hippocampal Neurogenesis via Activating the Wnt/β-Catenin Signaling Pathway in the APP/PS1/Nestin-GFP Triple Transgenic Mouse Model of Alzheimer’s Disease
- (2019) Qinghua Zeng et al. Frontiers in Aging Neuroscience
- Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease
- (2019) Elena P. Moreno-Jiménez et al. NATURE MEDICINE
- Quiescence Modulates Stem Cell Maintenance and Regenerative Capacity in the Aging Brain
- (2019) Georgios Kalamakis et al. CELL
- Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer’s Disease Patients
- (2019) Matthew K. Tobin et al. Cell Stem Cell
- Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling
- (2019) Yoshitaka Kase et al. Stem Cell Reports
- Is Alzheimer’s Disease a Neurogenesis Disorder?
- (2019) Se Hoon Choi et al. Cell Stem Cell
- Presymptomatic Treatment With Andrographolide Improves Brain Metabolic Markers and Cognitive Behavior in a Model of Early-Onset Alzheimer’s Disease
- (2019) Pedro Cisternas et al. Frontiers in Cellular Neuroscience
- Wnt5a promotes differentiation and development of adult-born neurons in the hippocampus by noncanonical Wnt signaling
- (2019) Sebastian B. Arredondo et al. STEM CELLS
- Human Hippocampal Neurogenesis Persists throughout Aging
- (2018) Maura Boldrini et al. Cell Stem Cell
- Impaired Wnt Signaling in the Prefrontal Cortex of Alzheimer’s Disease
- (2018) Jonas Folke et al. MOLECULAR NEUROBIOLOGY
- The role of adult hippocampal neurogenesis in brain health and disease
- (2018) Tomohisa Toda et al. MOLECULAR PSYCHIATRY
- Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults
- (2018) Shawn F. Sorrells et al. NATURE
- Tetrahydrohyperforin Increases Adult Hippocampal Neurogenesis in Wild-Type and APPswe/PS1ΔE9 Mice
- (2018) Ana C. Abbott et al. JOURNAL OF ALZHEIMERS DISEASE
- Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model
- (2018) Se Hoon Choi et al. SCIENCE
- The planar cell polarity protein VANG-1/Vangl negatively regulates Wnt/β-catenin signaling through a Dvl dependent mechanism
- (2018) Remco A. Mentink et al. PLoS Genetics
- Xanthoceraside modulates neurogenesis to ameliorate cognitive impairment in APP/PS1 transgenic mice
- (2017) Lin Zhu et al. Journal of Physiological Sciences
- Planar cell polarity in development and disease
- (2017) Mitchell T. Butler et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Adult hippocampal neurogenesis and cognitive flexibility — linking memory and mood
- (2017) Christoph Anacker et al. NATURE REVIEWS NEUROSCIENCE
- The amyloid hypothesis of Alzheimer's disease at 25 years
- (2016) Dennis J Selkoe et al. EMBO Molecular Medicine
- Activation of local inhibitory circuits in the dentate gyrus by adult-born neurons
- (2016) Liam J. Drew et al. HIPPOCAMPUS
- In vivo imaging of dendritic pruning in dentate granule cells
- (2016) J Tiago Gonçalves et al. NATURE NEUROSCIENCE
- Distinct Contribution of Adult-Born Hippocampal Granule Cells to Context Encoding
- (2016) Nathan B. Danielson et al. NEURON
- Human adult neurogenesis across the ages: An immunohistochemical study
- (2016) C. V. Dennis et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Hippocampal neurogenesis in the APP/PS1/nestin-GFP triple transgenic mouse model of Alzheimer’s disease
- (2016) Q. Zeng et al. NEUROSCIENCE
- Hippocampal neurogenesis: Learning to remember
- (2016) Orly Lazarov et al. PROGRESS IN NEUROBIOLOGY
- Frizzled-1 receptor regulates adult hippocampal neurogenesis
- (2016) Muriel D. Mardones et al. Molecular Brain
- Alzheimer's Disease and Hippocampal Adult Neurogenesis; Exploring Shared Mechanisms
- (2016) Carolyn Hollands et al. Frontiers in Neuroscience
- Age-related cognitive decline: Can neural stem cells help us?
- (2016) Benedetta Artegiani et al. Aging-US
- Wnt-Frizzled/Planar Cell Polarity Signaling: Cellular Orientation by Facing the Wind (Wnt)
- (2015) Yingzi Yang et al. Annual Review of Cell and Developmental Biology
- Andrographolide activates the canonical Wnt signalling pathway by a mechanism that implicates the non-ATP competitive inhibition of GSK-3β: autoregulation of GSK-3βin vivo
- (2015) Cheril Tapia-Rojas et al. BIOCHEMICAL JOURNAL
- Stage-Specific Changes in Neurogenic and Glial Markers in Alzheimer’s Disease
- (2015) Antigoni Ekonomou et al. BIOLOGICAL PSYCHIATRY
- Voluntary Running Attenuates Memory Loss, Decreases Neuropathological Changes and Induces Neurogenesis in a Mouse Model of Alzheimer's Disease
- (2015) Cheril Tapia-Rojas et al. BRAIN PATHOLOGY
- Canonical and noncanonical Wnt signaling in neural stem/progenitor cells
- (2015) Nora Bengoa-Vergniory et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Ethosuximide Induces Hippocampal Neurogenesis and Reverses Cognitive Deficits in an Amyloid-β Toxin-induced Alzheimer Rat Model via the Phosphatidylinositol 3-Kinase (PI3K)/Akt/Wnt/β-Catenin Pathway
- (2015) Shashi Kant Tiwari et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Aberrant Wnt signaling pathway in medial temporal lobe structures of Alzheimer’s disease
- (2015) Jesper Riise et al. JOURNAL OF NEURAL TRANSMISSION
- The Wnt Adaptor Protein ATP6AP2 Regulates Multiple Stages of Adult Hippocampal Neurogenesis
- (2015) S. T. Schafer et al. JOURNAL OF NEUROSCIENCE
- Maturation and Functional Integration of New Granule Cells into the Adult Hippocampus
- (2015) Nicolas Toni et al. Cold Spring Harbor Perspectives in Biology
- Adult Neurogenesis in Neurodegenerative Diseases: Figure 1.
- (2015) Beate Winner et al. Cold Spring Harbor Perspectives in Biology
- A septo-temporal molecular gradient of sfrp3 in the dentate gyrus differentially regulates quiescent adult hippocampal neural stem cell activation
- (2015) Jiaqi Sun et al. Molecular Brain
- Andrographolide Stimulates Neurogenesis in the Adult Hippocampus
- (2015) Lorena Varela-Nallar et al. NEURAL PLASTICITY
- Andrographolide reduces cognitive impairment in young and mature AβPPswe/PS-1 mice
- (2015) Felipe G Serrano et al. Molecular Neurodegeneration
- Targeting neurogenesis ameliorates danger assessment in a mouse model of Alzheimer's disease
- (2014) Adi Shruster et al. BEHAVIOURAL BRAIN RESEARCH
- Genetic manipulation of adult-born hippocampal neurons rescues memory in a mouse model of Alzheimer’s disease
- (2014) Kevin Richetin et al. BRAIN
- Wnt signalling in neuronal differentiation and development
- (2014) Nibaldo C. Inestrosa et al. CELL AND TISSUE RESEARCH
- Wnt/β-Catenin Signaling in Alzheimer’s Disease
- (2014) Giancarlo Ferrari et al. CNS & Neurological Disorders-Drug Targets
- The Wnt cries many: Wnt regulation of neurogenesis through tissue patterning, proliferation, and asymmetric cell division
- (2014) Holger Bielen et al. Developmental Neurobiology
- Neurogenesis in the Normal Ageing Hippocampus: A Mini-Review
- (2014) D�sir�e R.M. Seib et al. GERONTOLOGY
- Identification of Key Residues and Regions Important for Porcupine-mediated Wnt Acylation
- (2014) Jessica Rios-Esteves et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The cell biology of planar cell polarity
- (2014) Danelle Devenport JOURNAL OF CELL BIOLOGY
- Chronic hypoxia induces the activation of the Wnt/β-catenin signaling pathway and stimulates hippocampal neurogenesis in wild-type and APPswe-PS1ΔE9 transgenic mice in vivo
- (2014) Lorena Varela-Nallar et al. Frontiers in Cellular Neuroscience
- Wnt signaling in the nervous system and in Alzheimer's disease
- (2014) N. C. Inestrosa et al. Journal of Molecular Cell Biology
- Curcumin-Loaded Nanoparticles Potently Induce Adult Neurogenesis and Reverse Cognitive Deficits in Alzheimer’s Disease Model via Canonical Wnt/β-Catenin Pathway
- (2013) Shashi Kant Tiwari et al. ACS Nano
- Dynamics of Hippocampal Neurogenesis in Adult Humans
- (2013) Kirsty L. Spalding et al. CELL
- Loss of Dickkopf-1 Restores Neurogenesis in Old Age and Counteracts Cognitive Decline
- (2013) Désirée R.M. Seib et al. Cell Stem Cell
- Secreted Frizzled-Related Protein 3 Regulates Activity-Dependent Adult Hippocampal Neurogenesis
- (2013) Mi-Hyeon Jang et al. Cell Stem Cell
- Drosophila ATP6AP2/VhaPRR functions both as a novel planar cell polarity core protein and a regulator of endosomal trafficking
- (2013) Tobias Hermle et al. EMBO JOURNAL
- Wnt7a Regulates Multiple Steps of Neurogenesis
- (2013) Q. Qu et al. MOLECULAR AND CELLULAR BIOLOGY
- Wnt signaling in the regulation of adult hippocampal neurogenesis
- (2013) Lorena Varela-Nallar et al. Frontiers in Cellular Neuroscience
- The Role of Ryk and Ror Receptor Tyrosine Kinases in Wnt Signal Transduction
- (2013) J. Green et al. Cold Spring Harbor Perspectives in Biology
- Stearoyl CoA Desaturase Is Required to Produce Active, Lipid-Modified Wnt Proteins
- (2013) Jessica Rios-Esteves et al. Cell Reports
- Aging brain microenvironment decreases hippocampal neurogenesis through Wnt-mediated survivin signaling
- (2012) Carlos J. Miranda et al. AGING CELL
- Signaling mechanisms regulating adult neural stem cells and neurogenesis
- (2012) Roland Faigle et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Wnt/β-Catenin Signaling and Disease
- (2012) Hans Clevers et al. CELL
- Investigating Tonic Wnt Signaling Throughout the Adult CNS and in the Hippocampal Neurogenic Niche of BatGal and Ins-TopGal Mice
- (2012) David S. Garbe et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Stem cell maintenance in the adult mammalian hippocampus: A matter of signal integration?
- (2012) Tobias J. Schwarz et al. Developmental Neurobiology
- Optical controlling reveals time-dependent roles for adult-born dentate granule cells
- (2012) Yan Gu et al. NATURE NEUROSCIENCE
- A novel functional low-density lipoprotein receptor-related protein 6 gene alternative splice variant is associated with Alzheimer's disease
- (2012) Marcelo A. Alarcón et al. NEUROBIOLOGY OF AGING
- Unique Processing During a Period of High Excitation/Inhibition Balance in Adult-Born Neurons
- (2012) Antonia Marín-Burgin et al. SCIENCE
- Secreted and Transmembrane Wnt Inhibitors and Activators
- (2012) C.-M. Cruciat et al. Cold Spring Harbor Perspectives in Biology
- Wnt/Ca2+ signaling pathway: a brief overview
- (2011) Antara De ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Amyloid Precursor Protein Processing and Alzheimer's Disease
- (2011) Richard J. O'Brien et al. Annual Review of Neuroscience
- Wnt3a stimulation elicits G-protein-coupled receptor properties of mammalian Frizzled proteins
- (2011) Alexey Koval et al. BIOCHEMICAL JOURNAL
- In Vivo Clonal Analysis Reveals Self-Renewing and Multipotent Adult Neural Stem Cell Characteristics
- (2011) Michael A. Bonaguidi et al. CELL
- Division-Coupled Astrocytic Differentiation and Age-Related Depletion of Neural Stem Cells in the Adult Hippocampus
- (2011) Juan M. Encinas et al. Cell Stem Cell
- Voluntary Running and Environmental Enrichment Restores Impaired Hippocampal Neurogenesis in a Triple Transgenic Mouse Model of Alzheimers Disease
- (2011) J. J. Rodriguez et al. Current Alzheimer Research
- Wnt Signaling Gradients Establish Planar Cell Polarity by Inducing Vangl2 Phosphorylation through Ror2
- (2011) Bo Gao et al. DEVELOPMENTAL CELL
- Reduction in paracrine Wnt3 factors during aging causes impaired adult neurogenesis
- (2011) Masahiro Okamoto et al. FASEB JOURNAL
- 4- to 6-week-old adult-born hippocampal neurons influence novelty-evoked exploration and contextual fear conditioning
- (2011) Christine A. Denny et al. HIPPOCAMPUS
- Resolving New Memories: A Critical Look at the Dentate Gyrus, Adult Neurogenesis, and Pattern Separation
- (2011) James B. Aimone et al. NEURON
- Maturation time of new granule cells in the dentate gyrus of adult macaque monkeys exceeds six months
- (2011) S. J. Kohler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis
- (2011) O. Karalay et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Low proliferation and differentiation capacities of adult hippocampal stem cells correlate with memory dysfunction in humans
- (2010) R. Coras et al. BRAIN
- Wnt/Frizzled Signaling Requires dPRR, the Drosophila Homolog of the Prorenin Receptor
- (2010) Tina Buechling et al. CURRENT BIOLOGY
- Widespread deficits in adult neurogenesis precede plaque and tangle formation in the 3xTg mouse model of Alzheimer’s disease
- (2010) Laura K. Hamilton et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer’s disease-linked APPswe/PS1ΔE9 mice
- (2010) Yuan-Shih Hu et al. FASEB JOURNAL
- Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors
- (2010) L. Grumolato et al. GENES & DEVELOPMENT
- Effects of adult-generated granule cells on coordinated network activity in the dentate gyrus
- (2010) Clay O. Lacefield et al. HIPPOCAMPUS
- Wnt/beta-catenin is involved in the proliferation of hippocampal neural stem cells induced by hypoxia
- (2010) X.-P. Cui et al. IRISH JOURNAL OF MEDICAL SCIENCE
- Increased BMP6 Levels in the Brains of Alzheimer's Disease Patients and APP Transgenic Mice Are Accompanied by Impaired Neurogenesis
- (2010) L. Crews et al. JOURNAL OF NEUROSCIENCE
- Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice
- (2010) Michael Demars et al. JOURNAL OF NEUROSCIENCE RESEARCH
- New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?
- (2010) Wei Deng et al. NATURE REVIEWS NEUROSCIENCE
- Decreased numbers of progenitor cells but no response to antidepressant drugs in the hippocampus of elderly depressed patients
- (2010) Paul J. Lucassen et al. NEUROPHARMACOLOGY
- International Union of Basic and Clinical Pharmacology. LXXX. The Class Frizzled Receptors
- (2010) G. Schulte PHARMACOLOGICAL REVIEWS
- Murine Features of Neurogenesis in the Human Hippocampus across the Lifespan from 0 to 100 Years
- (2010) Rolf Knoth et al. PLoS One
- Lithium Improves Hippocampal Neurogenesis, Neuropathology and Cognitive Functions in APP Mutant Mice
- (2010) Anna Fiorentini et al. PLoS One
- Prox1 Is Required for Granule Cell Maturation and Intermediate Progenitor Maintenance During Brain Neurogenesis
- (2010) Alfonso Lavado et al. PLOS BIOLOGY
- Signaling in Adult Neurogenesis
- (2009) Hoonkyo Suh et al. Annual Review of Cell and Developmental Biology
- Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
- (2009) Bryan T. MacDonald et al. DEVELOPMENTAL CELL
- Wnt5a regulates distinct signalling pathways by binding to Frizzled2
- (2009) Akira Sato et al. EMBO JOURNAL
- Increased Dickkopf-1 expression in transgenic mouse models of neurodegenerative disease
- (2009) Maria Cristina Rosi et al. JOURNAL OF NEUROCHEMISTRY
- Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis
- (2009) Tomoko Kuwabara et al. NATURE NEUROSCIENCE
- Neurod1 is essential for the survival and maturation of adult-born neurons
- (2009) Zhengliang Gao et al. NATURE NEUROSCIENCE
- Wnt signaling in development and disease
- (2009) Jennifer L. Freese et al. NEUROBIOLOGY OF DISEASE
- Endogenous Wnt Signaling Maintains Neural Progenitor Cell Potency
- (2009) Eric M. Wexler et al. STEM CELLS
- Failure of Neuronal Maturation in Alzheimer Disease Dentate Gyrus
- (2008) Bin Li et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Early age-related changes in adult hippocampal neurogenesis in C57 mice
- (2008) Nada M.-B. Ben Abdallah et al. NEUROBIOLOGY OF AGING
- Impaired Adult Neurogenesis in the Dentate Gyrus of a Triple Transgenic Mouse Model of Alzheimer's Disease
- (2008) José J. Rodríguez et al. PLoS One
- Pattern Separation in the Human Hippocampal CA3 and Dentate Gyrus
- (2008) A. Bakker et al. SCIENCE
- Alternative Wnt Signaling Is Initiated by Distinct Receptors
- (2008) R. van Amerongen et al. Science Signaling
- Aging does not alter the number or phenotype of putative stem/progenitor cells in the neurogenic region of the hippocampus
- (2006) Bharathi Hattiangady et al. NEUROBIOLOGY OF AGING
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started